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Háttér és célkitűzések

A szakkádikus szemmozgási paraméterek biomarkerként történő önálló használata egyes degeneratív neuropszhichiátriai kórképek felismerésében egyelőre kérdéses. Jelen vizsgálatunk célkitűzése egy olyan szakkádikus szemmozgásvizsgálati protokoll megvalósítása, amely a nemzetközi klinikai kutatásoknak megfelelően kialakított vizsgálati paraméterekkel jellemezhető. Továbbá egészséges vizsgált személyek szakkádparamétereinek a nemzetközileg publikált adatokkal való összehasonlítása, illetve a Boston Sütilopás feladatban használt kép vizuális tesztkörnyezetbe történő beépítésének disztraktor-hatásvizsgálata a szakkádikus paraméterekre.

Módszer

Vizsgálatainkat egészséges önkéntes alanyokon végeztük Tobii Pro X3-120 berendezéssel, két eltérő vizuális környezetet tartalmazó, egyéb tekintetben teljesen megegyező felépítésű, proszakkád és antiszakkád tesztek gap és overlap feladataiban. Az egyik csoport vizuális tesztkörnyezete standard szürke háttérből és fekete stimulusokból állt (STD tesztcsoport), a másiké a Boston Afázia Teszt Sütilopás képleírási feladatban használt képet és zöld-piros színű stimulusokat tartalmazott (BSL tesztcsoport).

Eredmények

A proszakkád és antiszakkád overlap latencia mindkét csoportban nagyobb volt, mint a gap feladatban. A vizsgálati alanyok életkora közepes erősségű módon korrelált az STD csoport proszakkád gap latenciájával, illetve a BSL csoport proszakkád overlap latencia, antiszakkád gap/overlap latencia és overlap időtartam értékével. A csoportok közötti életkori eltérés statisztikai kontrollja mellett nem találtunk különbséget a proszakkád és antiszakkád latencia, illetve csúcssebesség tekintetében. A szakkád időtartamok szignifi kánsan rövidebbek voltak a BSL csoportban. Az iránytévesztési ráta a proszakkád tesztben megegyezett; az antiszakkád gap időtartam, az overlap időtartam, illetve a gap iránytévesztési ráta szignifi káns csoportkülönbséget mutatott.

Következtetések

A nemzetközi sztenderdeknek megfelelő újszerű vizsgálati protokoll alkalmasnak látszik hagyományos neuropszichológiai tesztekkel és kutatócsoportunk közelmúltban kidolgozott automatikus beszédfelismerő algoritmusokat alkalmazó tesztjeivel kombinálva egészséges és demencia szindrómával élő személyek multimodális klinikai vizsgálatában történő felhasználásra.

Background and aims

The use of saccadic parameters as specifi c biomarkers in the diagnosis of degenerative neuropsychiatric disorders is still problematic. The aim of the current study was to 1) establish a protocol for saccadic eye movement measurements that is concordant with international clinical investigations; 2) compare saccadic parameters of healthy subjects with internationally published data, and 3) integrate the picture from Boston Cookie Theft test into the visual test environment and evaluate its distractor effects on saccadic parameters.

Methods

Healthy volunteers were assessed with Tobii Pro X3-120 eye tracker in two distinct visual settings, but otherwise identical test environment evaluating prosaccades and antisaccades in gap and overlap conditions. One group was assessed in a visual test environment based on a traditional uniform grey background with black stimuli (STD test group), while the visual test environment of the other group contained the Cookie Theft picture of the Boston Diagnostic Aphasia Examination with green and red stimuli (BSL group).

Results

Prosaccade and antisaccade latencies were signifi cantly longer in the overlap condition both in the BSL and STD groups. After controlling for age, the STD and BSL group did not differ in terms of prosaccade latency, antisaccade latency or peak velocity; only saccade durations were shorter in the BSL group. Saccadic direction error rate in the prosaccade task was identical in both groups, while the antisaccade gap duration, overlap duration and gap direction error rates showed signifi cant group differences.

The present, newly developed protocol conforms to international standards, and may be useful for multi-modal clinical studies assessing healthy subjects and people suffering from dementia, combined with traditional neuropsychological tasks and the speech recognition task recently developed by our research group.

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Senior editors

Editor(s)-in-Chief: Fülöp, Márta

Chair of the Editorial Board:
Molnár, Márk

          Area Editors

  • Bereczkei Tamás (Evolutionary psychology)
  • Demetrovics Zsolt (Clinical psychology)
  • Egyed Katalin (Developmental psychology)
  • Hámori Eszter (Clinical child psychology)
  • Molnárné Kovács Judit (Social psychology)
  • Rózsa Sándor (Personality psychology and psychometrics)
  • Nguyen Luu Lan Anh (Cross-cultural psychology)
  • Pléh Csaba (Book Review)
  • Sass Judit (Industrial and organizational psychology)
  • Szabó Éva (Educational psychology)
  • Urbán Róbert (Health psychology)
  • Csákvári Judit (Psychology of special education)
  • Faragó Klára (Organizational psychology)
  • Kéri Szabolcs (Experimental and Neuropsychology)

 

        Editorial Board

  • Czigler István
  • Császár Noémi
  • Csépe Valéria
  • Dúll Andrea
  • Ehmann Bea
  • Fülöp Márta
  • Gervai Judit
  • Kiss Enikő Csilla
  • Kiss Paszkál
  • Mészáros Judit
  • Molnár Márk
  • Németh Dezső
  • Oláh Attila
  • Péley Bernadette
  • Perczel-Forintos Dóra
  • Révész György
  • Winkler István

 

Secretary of the editorial board: 

  •  Saád Judit

 

Magyar Pszichológiai Szemle
ELTE PPK Pszichológiai Intézet
Address: H-1064 Budapest, Izabella u. 46.
E-mail: pszichoszemle@gmail.com

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2020  
Scimago
H-index
7
Scimago
Journal Rank
0,142
Scimago
Quartile Score
Psychology (miscellaneous) Q4
Scopus
Cite Score
17/111=0,2
Scopus
Cite Score Rank
General Psychology 199/203 (Q4)
Scopus
SNIP
0,079
Scopus
Cites
53
Scopus
Documents
24
Days from submission to acceptance 116
Days from acceptance to publication 225
Acceptance
Rate
81%

 

2019  
Scimago
H-index
6
Scimago
Journal Rank
0,139
Scimago
Quartile Score
Psychology (miscellaneous) Q4
Scopus
Cite Score
24/103=0,2
Scopus
Cite Score Rank
General Psychology 192/204 (Q4)
Scopus
SNIP
0,113
Scopus
Cites
35
Scopus
Documents
14
Acceptance
Rate
58%

 

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Magyar Pszichológiai Szemle
Language Hungarian
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1928
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2021 Volume 76
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ISSN 0025-0279 (Print)
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