View More View Less
  • 1 State Breeding Institute Nitra, Slovak Republic
  • 2 State Breeding Institute Nitra, Slovak Republic
  • 3 State Breeding Institute Nitra, Slovak Republic
  • 4 State Breeding Institute Nitra, Slovak Republic
  • 5 University of Veterinary Medicine Košice, Slovak Republic
  • 6 University of Veterinary Medicine Košice, Slovak Republic
  • 7 Department of Animal Breeding, Nutrition and Laboratory Animal Science, Faculty of Veterinary Science, Szent István University H-1078 Budapest, István u. 2, Hungary
  • 8 State Breeding Inspection Nitra, Slovak Republic
  • 9 Research Institute of Animal Production Nitra, Slovak Republic
Restricted access

Purchase article

USD  $25.00

1 year subscription (Individual Only)

USD  $836.00

Genetic variation at six microsatellite loci was analysed for five Thoroughbred subpopulations to determine the magnitude of genetic differentiation and the genetic relationships among the subpopulations. Significant deviations from Hardy-Weinberg equilibrium were shown for a number of locus-population combinations, with all subpopulations. The genetic diversities and relationships of five Thoroughbred subpopulations were evaluated using six microsatellites recommended by the International Society of Animal Genetics (ISAG). The allele frequencies, the effective numbers of alleles, and the observed and expected heterozygosities were calculated. POPGENE v. 1.31 (Yeh et al., 1997) was used to test for deviations from the Hardy-Weinberg (H-W) equilibrium and to assign FIS estimates (Weir, 1990). The utility of microsatellites for evaluating genetic diversity of horses is discussed.

  • Garza, J. C., Sladkin, M. and Freimer, N. B. (1995): Microsatellite allele frequencies in humans and chimpanzees, with implications for constraints on allele size. Mol. Biol. Evol. 12, 594-603.

    'Microsatellite allele frequencies in humans and chimpanzees, with implications for constraints on allele size. ' () 12 Mol. Biol. Evol. : 594 -603.

    • Search Google Scholar
  • Guérin, G., Bertaud, M. and Amigues, Y. (1994): Characterization of seven new horse microsatellites: HMS1, HMS2, HMS3, HMS5, HMS6, HMS7 and HMS8. Animal Genetics 25, 62.

    'Characterization of seven new horse microsatellites: HMS1, HMS2, HMS3, HMS5, HMS6, HMS7 and HMS8. ' () 25 Animal Genetics : 62..

    • Search Google Scholar
  • Hartl, D. L. and Clark, A. G. (1989): Principles of Population Genetics. 2nd edition. Sinauer Associates, Sunderland, MA.

    Principles of Population Genetics. , ().

  • Allen, P. J., Amos, W., Pomeroy, P. P. and Twiss, S. D. (1995): Microsatellite variation in grey seals show evidence of genetic differentiation between two British breeding colonies. Mol. Ecol. 4, 653-662.

    'Microsatellite variation in grey seals show evidence of genetic differentiation between two British breeding colonies. ' () 4 Mol. Ecol. : 653 -662.

    • Search Google Scholar
  • Breen, M., Lindgren, G., Binns, M. M., Norman, J., Irvin, Z., Bell, K., Sandberg, K. and Ellegren, H. (1997): Genetical and physical assignments of equine microsatellites - first integration of anchored markers in horse genome mapping. Mammalian Genome 8, 267-273.

    'Genetical and physical assignments of equine microsatellites - first integration of anchored markers in horse genome mapping. ' () 8 Mammalian Genome : 267 -273.

    • Search Google Scholar
  • Bowcock, A. M., Ruiz-Linares, A., Tomfohrde, J., Minch, E., Kidd, J. R. and Cavalli-Sforza, L. L. (1994): High resolution of human evolution with microsatellites. Nature 368, 455-457.

    'High resolution of human evolution with microsatellites. ' () 368 Nature : 455 -457.

  • Edwards, A., Hammond, H. A., Jin, L., Caskey, C. T. and Chakraborty, R. (1992): Genetic variation at five trimeric and tetrameric tandem repeats. Genomics 12, 241-253.

    'Genetic variation at five trimeric and tetrameric tandem repeats. ' () 12 Genomics : 241 -253.

    • Search Google Scholar
  • Ellegren, H., Johansson, M., Sandberg, K. and Andersson, L. (1992): Cloning of highly polymorphic microsatellites in the horse. Animal Genetics 23, 133-142.

    'Cloning of highly polymorphic microsatellites in the horse. ' () 23 Animal Genetics : 133 -142..

    • Search Google Scholar
  • Estoup, A., Solinac, M., Cournuet, J.-M., Goudet, J. and Scholl, A. (1996): Genetic differentiation of continental and island populations of Bombus terrestris in Europe. Mol. Ecol. 5, 19-31.

    'Genetic differentiation of continental and island populations of Bombus terrestris in Europe. ' () 5 Mol. Ecol. : 19 -31.

    • Search Google Scholar
  • Jeffreys, A. J., Royale, N. J., Wilson, V. and Wong, Z. (1988): Spontaneous mutation rates to new alleles at tandem repetitive hypervariable loci in human DNA. Nature 332, 278-281.

    'Spontaneous mutation rates to new alleles at tandem repetitive hypervariable loci in human DNA. ' () 332 Nature : 278 -281.

    • Search Google Scholar
  • Kelly, R., Gibbs, M., Collick, A. and Jeffreys, A. J. (1991): Spontaneous mutation at hypervariable mouse minisatellite locus Ms6 - hm: flanking DNA sequence and analysis of germline and early somatic events. Proc. R. Soc. Lond. Ser. B Biol. Sci. 245, 235-245.

    'Spontaneous mutation at hypervariable mouse minisatellite locus Ms6 - hm: flanking DNA sequence and analysis of germline and early somatic events. ' () 245 Proc. R. Soc. Lond. Ser. B Biol. Sci. : 235 -245..

    • Search Google Scholar
  • Kimura, M. and Crow, J. F. (1964): The number of alleles that can be maintained in a finite population. Genetics 49, 725-738.

    'The number of alleles that can be maintained in a finite population. ' () 49 Genetics : 725 -738.

    • Search Google Scholar
  • Lade, J. A., Murray, N. D., Marks, C. A. and Robinson, N. A. (1996): Microsatellite differentiation between Phillip island and mainland Australian populations of the red fox (Vulpes vulpes). Mol. Ecol. 5, 81-87.

    'Microsatellite differentiation between Phillip island and mainland Australian populations of the red fox (Vulpes vulpes). ' () 5 Mol. Ecol. : 81 -87..

    • Search Google Scholar
  • Nei, M. (1973): Analysis of gene diversity in subdivided populations. Proc. Natl. Acad. Sci. USA 70, 3321-3323.

    'Analysis of gene diversity in subdivided populations. ' () 70 Proc. Natl. Acad. Sci. USA : 3321 -3323..

    • Search Google Scholar
  • Queller, D. C., Strassmann, J. E. and Hughes, C. R. (1993): Microsatellites and kinship. Trends Ecol. Evol. 8, 285-288.

    'Microsatellites and kinship. ' () 8 Trends Ecol. Evol. : 285 -288..

  • Yeh, F. C., Yang, R.-C., Boyle, T. B. J., Ye, Z.-H. and Mao, J. X. (1997): Popgene, the userfriendly shareware for population genetic analysis. Molecular Biology and Biotechnology Center, University of Alberta, Canada.

    Popgene, the userfriendly shareware for population genetic analysis. , ().

  • Weber, J. L. and Wong, C. (1993): Mutation of human short tandem repeats. Hum. Mol. Genet. 2, 1123-1128.

    'Mutation of human short tandem repeats. ' () 2 Hum. Mol. Genet. : 1123 -1128..

  • Weissenbach, J., Gyapay, G., Dib, C., Vignal, A., Morisette, J., Millaseau, P., Vaysseix, G. and Lathrop, M. (1992): A second generation linkage map of the human genome. Nature 359, 794-801.

    'A second generation linkage map of the human genome. ' () 359 Nature : 794 -801..

  • Weir, B. S. (1990): Genetic Data Analysis. Sinauer Associates, Sunderland, MA.

    Genetic Data Analysis. , ().

  • Paetkau, D. and Strobeck, C. (1995): The molecular basis and evolutionary history of microsatellite null allele in bears. Mol. Ecol. 4, 519-520.

    'The molecular basis and evolutionary history of microsatellite null allele in bears. ' () 4 Mol. Ecol. : 519 -520..

    • Search Google Scholar
  • Shriver, M. D., Jin, L., Chakraborty, R. and Boerwinkle, E. (1993): VNTR allele frequency distributions under the stepwise mutation model: a computer simulation approach. Genetics 134, 983-993.

    'VNTR allele frequency distributions under the stepwise mutation model: a computer simulation approach. ' () 134 Genetics : 983 -993..

    • Search Google Scholar
  • Tautz, D. (1993): Notes on the definition and nomenclature of tandemly repetitive DNA sequences. In: Pena, S. D. J., Chakraborty, R., Epplen, J. T. and Jeffreys, A. J. (eds) DNA Fingerprinting. State of the Science. Birkhauser Verlag, Basel. pp. 21-28.

    Notes on the definition and nomenclature of tandemly repetitive DNA sequences. , () 21 -28..

    • Search Google Scholar
  • Van Haeringen, H., Bowling, A. T., Stott, M. L., Lenstra, J. A. and Zwaagstra, K. A. (1994): A highly polymorphic horse microsatellite locus: VHL20. Animal Genetics 25, 207.

    'A highly polymorphic horse microsatellite locus: VHL20. ' () 25 Animal Genetics : 207.

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Sep 2020 2 0 0
Oct 2020 3 0 0
Nov 2020 3 0 0
Dec 2020 8 0 0
Jan 2021 3 0 0
Feb 2021 1 0 0
Mar 2021 0 0 0