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  • 1 Szent István University Department of Animal Hygiene, Herd Health and Veterinary Ethology, Faculty of Veterinary Science István u. 2 H-1078 Budapest Hungary
  • 2 Szent István University Clinic for Large Animals, Faculty of Veterinary Science Üllő Hungary
  • 3 Szent István University Department of Biomathematics and Informatics, Faculty of Veterinary Science Budapest Hungary
  • 4 Private Veterinarian Martonvásár Hungary
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The objective of this study was to determine some metabolic and other factors predicting the risk of postpartum uterine disease (PUD), and the effects of puerperal metritis (PM) on metabolic status, reproduction and milk yield were analysed. A total of 105 Holstein-Friesian cows were included, and sampled on day < −14 prepartum and days 4, 10–14, 28–35 and 56–63 postpartum for metabolic tests. From day 4 the development of PUD, and from days 28–35 the ovarian activity was monitored. When grade ≥ 1 + ketonuria was present on day 4 postpartum, this indicated a higher probability of PUD [odds ratio (OR) 2.64; P < 0.05] including PM occurring on days 10–14 (OR: 2.65; P < 0.05). Plasma nonesterified fatty acid (NEFA) concentrations > 0.200 mmol/l on days < −14 prepartum indicated a higher risk of uterine diseases (OR: 3.44; P < 0.05). The odds of PUD increased, depending on whether a body condition score (BCS) loss of ≥ 1.0 occurred between days < −14 and 28–35 (OR: 2.82; P < 0.05), between days < −14 and 10–14 (OR: 4.79; P < 0.01) or between days 10–14 and 28–35 (OR: 10.81; P < 0.01). PM was more probable (OR: 27.3; P < 0.001) in cows with retained placenta. The risk of uterine diseases was lower in multiparous than in primiparous cows (OR: 0.29; P < 0.01). PM increased the risk of ovarian inactivity between days 28 and 35 (OR: 2.83; P < 0.05). Cows affected with PM (PM+ cows) showed lower milk production on day 4 (kg; P < 0.05) and lower milk production (P < 0.05), milk fat and milk protein production (kg; P < 0.01; P < 0.01) in the first 100 days of lactation than did PM− cows.

  • Agresti, A. (1990): Categorical Data Analysis. Wiley, New York. pp. 59–66.

    Agresti A. , '', in Categorical Data Analysis , (1990 ) -.

  • Bertics, S. J., Grummer, R. R., Cadorniga-Valino, C., LaCount, D. W. and Stoddard, E. E. (1992): Effect of prepartum dry matter intake on liver triglyceride concentration and postpartum lactation. J. Dairy Sci. 75 , 1914–1922.

    Stoddard E. E. , 'Effect of prepartum dry matter intake on liver triglyceride concentration and postpartum lactation ' (1992 ) 75 J. Dairy Sci. : 1914 -1922.

    • Search Google Scholar
  • Brydl, E. (1995): Prevention of peripartal metabolic disorders with multiphase feeding in dairy cows (in Hungarian, with English abstract). Magyar Állatorvosok Lapja 50 , 600–607.

    Brydl E. , 'Prevention of peripartal metabolic disorders with multiphase feeding in dairy cows (in Hungarian, with English abstract) ' (1995 ) 50 Magyar Állatorvosok Lapja : 600 -607.

    • Search Google Scholar
  • Brydl, E., Jurkovich, V., Könyves, L., Tegzes, L. and Kálmán, I. (2003): Occurrence of subclinical metabolic disorders in dairy cows in Hungary in 2001 (in Hungarian, with English abstract). Magyar Állatorvosok Lapja 125 , 393–400.

    Kálmán I. , 'Occurrence of subclinical metabolic disorders in dairy cows in Hungary in 2001 (in Hungarian, with English abstract) ' (2003 ) 125 Magyar Állatorvosok Lapja : 393 -400.

    • Search Google Scholar
  • De Rensis, F. and Scaramuzzi, R. J. (2003): Heat stress and seasonal effects on reproduction in the dairy cow — a review. Theriogenology 60 , 1139–1151.

    Scaramuzzi R. J. , 'Heat stress and seasonal effects on reproduction in the dairy cow — a review ' (2003 ) 60 Theriogenology : 1139 -1151.

    • Search Google Scholar
  • Dirksen, G. H., Liebich, H. G. and Mayer, E. (1999): Adaptive changes of the ruminal mucosa and their functional and clinical significance. Bov. Pract. 20 , 116–120.

    Mayer E. , 'Adaptive changes of the ruminal mucosa and their functional and clinical significance ' (1999 ) 20 Bov. Pract. : 116 -120.

    • Search Google Scholar
  • Gaál, T., Roberts, C. J., Reid, I. M., Dew, A. M. and Copp, C. M. (1983): Blood composition and liver fat in post parturient dairy cows. Vet. Rec. 113 , 53–54.

    Copp C. M. , 'Blood composition and liver fat in post parturient dairy cows ' (1983 ) 113 Vet. Rec. : 53 -54.

    • Search Google Scholar
  • Goff, J. P. (2003): Managing the transition cow — considerations for optimising energy and protein balance and immune function. Cattle Pract. 11 , 51–63.

    Goff J. P. , 'Managing the transition cow — considerations for optimising energy and protein balance and immune function ' (2003 ) 11 Cattle Pract. : 51 -63.

    • Search Google Scholar
  • Grummer, R. R. (1995): Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. J. Anim. Sci. 73 , 2820–2833.

    Grummer R. R. , 'Impact of changes in organic nutrient metabolism on feeding the transition dairy cow ' (1995 ) 73 J. Anim. Sci. : 2820 -2833.

    • Search Google Scholar
  • Grummer, R. R., Mashek, D. G. and Hayrili, A. (2004): Dry matter intake and energy balance in the transition period. Vet. Clin. Food Anim. Sci. 20 , 447–470.

    Hayrili A. , 'Dry matter intake and energy balance in the transition period ' (2004 ) 20 Vet. Clin. Food Anim. Sci. : 447 -470.

    • Search Google Scholar
  • Haraszti, J. (1993): Sexual function and reproductive disorders of the cow (Chapter II. 1). In: Haraszti, J. and Zöldág, L. (eds) Obstetrics and Reproduction of Domestic Animals (in Hungarian). Mezőgazda Kiadó, Budapest. pp. 327–415.

    Haraszti J. , '', in Obstetrics and Reproduction of Domestic Animals (in Hungarian) , (1993 ) -.

    • Search Google Scholar
  • Harris, T. G., Battaglia, D. F., Brown, M. E., Brown, M. B., Carlson, N. E., Viguie, C., Williams, C. Y. and Karsch, F. J. (2000): Prostaglandins mediate the endotoxin-induced suppression of pulsatile gonadotropin-releasing hormone and luteinising hormone secretion in the ewe. Endocrinology 141 , 1050–1058.

    Karsch F. J. , 'Prostaglandins mediate the endotoxin-induced suppression of pulsatile gonadotropin-releasing hormone and luteinising hormone secretion in the ewe ' (2000 ) 141 Endocrinology : 1050 -1058.

    • Search Google Scholar
  • Hayrili, A., Grummer, R. R., Nordheim, E. V. and Cump, P. M. (2002): Animal and dietary factors affecting feed intake during the pre-fresh transition period in Holsteins. J. Dairy Sci. 85 , 3430–3443.

    Cump P. M. , 'Animal and dietary factors affecting feed intake during the pre-fresh transition period in Holsteins ' (2002 ) 85 J. Dairy Sci. : 3430 -3443.

    • Search Google Scholar
  • Hollander, M. and Wolfe, D. A. (1999): Nonparametric Statistical Methods. Second edition. John Wiley and Sons, New York. pp. 27–33 and 68–75.

    Wolfe D. A. , '', in Nonparametric Statistical Methods , (1999 ) -.

  • Holtenius, K., Agenas, S., Delavaud, C. and Chilliard, Y. (2003): Effects of feed intensity during the dry period. 2. Metabolic and hormonal responses. J. Dairy Sci. 86 , 883–891.

    Chilliard Y. , 'Effects of feed intensity during the dry period. 2. Metabolic and hormonal responses ' (2003 ) 86 J. Dairy Sci. : 883 -891.

    • Search Google Scholar
  • Husvéth, F., Karsai, F. and Gaál, T. (1982): Changes in certain lipid components of the blood plasma and liver of dairy cows during the perinatal period (in Hungarian, with English abstract). Magyar Állatorvosok Lapja 37 , 689–696.

    Gaál T. , 'Changes in certain lipid components of the blood plasma and liver of dairy cows during the perinatal period (in Hungarian, with English abstract) ' (1982 ) 37 Magyar Állatorvosok Lapja : 689 -696.

    • Search Google Scholar
  • Huszenicza, Gy., Fodor, M., Gacs, M., Kulcsár, M., Dohmen, M. J. W., Vámos, M., Porkoláb, L., Kégl, T., Bartyik, J., Lohuis, J. H. C. M., Jánosi, Sz. and Szita, G. (1999): Uterine bacteriology, resumption of cyclic ovarian activity and fertility in postpartum cows kept in larges-cale dairy herds. Reprod. Domest. Anim. 34 , 237–245.

    Szita G. , 'Uterine bacteriology, resumption of cyclic ovarian activity and fertility in postpartum cows kept in larges-cale dairy herds ' (1999 ) 34 Reprod. Domest. Anim. : 237 -245.

    • Search Google Scholar
  • Huszenicza, Gy., Kulcsár, M., Dieleman, S. J., Nikolic, J. A., Jánosi, Sz., Kóródi, P., Kátai, L., Bartyik, J. and Rudas, P. (1998): Endocrine alterations and resumption of cyclic ovarian function in dairy cows affected by various forms of hyperketonaemia in early weeks of lactation. In: Wensing, T. (ed.) Production Diseases in Farm Animals. Book of Abstracts of 10th IPCD, 24–28 August, Utrecht, The Netherlands, Wageningen Press, p. 239.

    Rudas P. , '', in Production Diseases in Farm Animals. Book of Abstracts of 10th IPCD , (1998 ) -.

    • Search Google Scholar
  • Huszenicza, Gy., Kulcsár, M. and Rudas, P. (2002): Clinical endocrinology of thyroid gland function in ruminants. Vet. Med. Czech 47 , 199–210.

    Rudas P. , 'Clinical endocrinology of thyroid gland function in ruminants ' (2002 ) 47 Vet. Med. Czech : 199 -210.

    • Search Google Scholar
  • Ingvartsen, K. L. (2006): Feeding and management-related diseases in the transition cow. Physiological adaptations around calving and strategies to reduce feeding-related diseases. Anim. Feed Sci. Technol. 126 , 175–213.

    Ingvartsen K. L. , 'Feeding and management-related diseases in the transition cow. Physiological adaptations around calving and strategies to reduce feeding-related diseases ' (2006 ) 126 Anim. Feed Sci. Technol. : 175 -213.

    • Search Google Scholar
  • Jorritsma, R., Wensing, T., Kruip, T. A. M., Vos, P. L. A. M. and Noordhuizen, J. P. T. M. (2003): Metabolic changes in early lactation and impaired reproductive performance in dairy cows. Vet. Res. 34 , 11–26.

    Noordhuizen J. P. T. M. , 'Metabolic changes in early lactation and impaired reproductive performance in dairy cows ' (2003 ) 34 Vet. Res. : 11 -26.

    • Search Google Scholar
  • Kaneene, J. B. and Miller, R. (1995): Risk factors for metritis in Michigan dairy cattle using herd- and cow-based modelling approaches. Prev. Vet. Med. 23 , 183–200.

    Miller R. , 'Risk factors for metritis in Michigan dairy cattle using herd- and cow-based modelling approaches ' (1995 ) 23 Prev. Vet. Med. : 183 -200.

    • Search Google Scholar
  • Kim, I. H. and Suh, G. H. (2003): Effect of the amount of body condition loss from the dry to near calving periods on the subsequent body condition change, occurrence of postpartum diseases, metabolic parameters and reproductive performance in Holstein dairy cows. Theriogenology 60 , 1445–1456.

    Suh G. H. , 'Effect of the amount of body condition loss from the dry to near calving periods on the subsequent body condition change, occurrence of postpartum diseases, metabolic parameters and reproductive performance in Holstein dairy cows ' (2003 ) 60 Theriogenology : 1445 -1456.

    • Search Google Scholar
  • Könyves, L., Szenci, O., Jurkovich, V., Tegzes, L., Tirián, A., Solymosi, N., Gyulay, Gy. and Brydl, E. (2009): Periparturient risk assessment for retained placenta in dairy cows. Acta Vet. Brno (submitted for publication).

  • Kutas, F. (1965): Determination of net acid-base excretion in the urine of cattle. Acta Vet. Hung. 15 , 147–153.

    Kutas F. , 'Determination of net acid-base excretion in the urine of cattle ' (1965 ) 15 Acta Vet. Hung. : 147 -153.

    • Search Google Scholar
  • Maizon, D. O., Oltenacu, P. A., Gröhn, Y. T., Srawderman, R. L. and Emanuelson, U. (2004): Effects of diseases on reproductive performance in Swedish Red and White dairy cattle. Prev. Vet. Med. 66 , 113–126.

    Emanuelson U. , 'Effects of diseases on reproductive performance in Swedish Red and White dairy cattle ' (2004 ) 66 Prev. Vet. Med. : 113 -126.

    • Search Google Scholar
  • Mateus, L., Lopes da Costa, L., Diniz, P. and Ziecik, A. J. (2003): Relationship between endotoxin and prostaglandin (PGE 2 and PGFM) concentrations and ovarian function in dairy cows with puerperal endometritis. Anim. Reprod. Sci. 76 , 143–154.

    Ziecik A. J. , 'Relationship between endotoxin and prostaglandin (PGE2 and PGFM) concentrations and ovarian function in dairy cows with puerperal endometritis ' (2003 ) 76 Anim. Reprod. Sci. : 143 -154.

    • Search Google Scholar
  • Mulligan, F. J., O’Grady, L., Rice, D. A. and Doherty, M. L. (2006): A herd health approach to dairy cow nutrition and production diseases of the transition cow. Anim. Reprod. Sci. 96 , 331–353.

    Doherty M. L. , 'A herd health approach to dairy cow nutrition and production diseases of the transition cow ' (2006 ) 96 Anim. Reprod. Sci. : 331 -353.

    • Search Google Scholar
  • Mulvany, P. (1977): Dairy cow condition scoring. NIRD paper No. 4468.

  • Opsomer, G., Grohn, I. T., Hertl, J., Coryn, M., Deluyker, H. and de Kruif, A. (2000): Risk factors for post partum ovarian dysfunction in high producing dairy cows in Belgium: a field study. Theriogenology 53 , 841–857.

    Kruif A. , 'Risk factors for post partum ovarian dysfunction in high producing dairy cows in Belgium: a field study ' (2000 ) 53 Theriogenology : 841 -857.

    • Search Google Scholar
  • Sheldon, I. M., Lewis, G. S., LeBlanc, S. and Gilbert, R. O. (2006): Defining postpartum uterine disease in cattle. Theriogenology 65 , 1516–1530.

    Gilbert R. O. , 'Defining postpartum uterine disease in cattle ' (2006 ) 65 Theriogenology : 1516 -1530.

    • Search Google Scholar
  • Thatcher, W. W., Bilby, T. L., Bartolome, J. A., Silvestre, F., Staples, C. R. and Santos, J. E. P. (2006): Strategies to improve fertility in the modern dairy cow. Theriogenology 65 , 30–44.

    Santos J. E. P. , 'Strategies to improve fertility in the modern dairy cow ' (2006 ) 65 Theriogenology : 30 -44.

    • Search Google Scholar
  • Valz, P. D. and Thompson, M. E. (1994): Exact inference for Kendall’s S and Spearman’s Rho with extensions to Fisher’s exact test in r × c contingency tables. J. Comput. Graph. Stat. 3 , 459–472.

    Thompson M. E. , 'Exact inference for Kendall’s S and Spearman’s Rho with extensions to Fisher’s exact test in r × c contingency tables ' (1994 ) 3 J. Comput. Graph. Stat. : 459 -472.

    • Search Google Scholar
  • Walker, P. G. (1954): A colorimetric method for the estimation of acetoacetate. Biochem. J. 58 , 699–704.

    Walker P. G. , 'A colorimetric method for the estimation of acetoacetate ' (1954 ) 58 Biochem. J. : 699 -704.

    • Search Google Scholar
  • Williams, C. Y., Harris, T. G., Battaglia, D. F., Viguié, C. and Krasch, F. J. (2001): Endotoxin inhibits pituitary responsiveness to gonadotropin-releasing hormone. Endocrinology 142 , 1915–1922.

    Krasch F. J. , 'Endotoxin inhibits pituitary responsiveness to gonadotropin-releasing hormone ' (2001 ) 142 Endocrinology : 1915 -1922.

    • Search Google Scholar
  • Yeon-Kyung, H. and Ill-Hwa, K. (2005): Risk factors for retained placenta and the effect of retained placenta on the occurrence of postpartum diseases and subsequent reproductive performance in dairy cows. J. Vet. Sci. 6 , 53–59.

    Ill-Hwa K. , 'Risk factors for retained placenta and the effect of retained placenta on the occurrence of postpartum diseases and subsequent reproductive performance in dairy cows ' (2005 ) 6 J. Vet. Sci. : 53 -59.

    • Search Google Scholar
  • Zamet, C. N., Colenbrander, V. F., Erb, R. E., Callahan, C. J., Chew, B. P. and Moeller, N. J. (1979): Variables associated with peripartum traits in dairy cows. Interrelationships among disorders and their effects on intake of feed and on intake on reproductive efficiency. Theriogenology 11 , 245–260.

    Moeller N. J. , 'Variables associated with peripartum traits in dairy cows. Interrelationships among disorders and their effects on intake of feed and on intake on reproductive efficiency ' (1979 ) 11 Theriogenology : 245 -260.

    • Search Google Scholar

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