The aim of the study was to establish normal reference echocardiographic values for three Hungarian dog breeds, and to determine the potential dependence of intracardiac parameters on body weight, age and gender. M-mode and two-dimensional echocardiography were performed on 95 clinically healthy dogs including 45 Hungarian Vizslas, 28 Mudis and 22 Hungarian Greyhounds. Linear intracardiac measurements included interventricular septal thickness (IVS), left ventricular internal diameter (LVID), left ventricular posterior wall thickness (LVPW) both in systole and diastole, as well as left atrial internal diameter (LAD), and aortic diameter (AOD) in early diastole. Fractional shortening (FS), end-diastolic and end-systolic left ventricular volumes (EDV and ESV), as well as LAD:AOD ratio were calculated from the linear parameters. Mean, range and standard deviation of measurements were calculated for each breed. Body weight positively correlated in all three breeds with all left ventricular dimensions, such as IVS d , IVS s , LVID d , LVIDD s , LVPW d and LVPW s parameters. LA values showed positive correlations to body weight in all three breeds. AOD and LA demonstrated a positive correlation with body weight in Hungarian Vizslas and Mudis, whilst the LAD:AOD ratio was related to body weight only in Mudis. Gender did not correlate with any of the measured echocardiographic parameters in any breeds. In Mudis, a positive correlation was found between the LAD:AOD ratio and age, as well as between the LAD:AOD ratio and E point to septal separation (EPSS).
Baade, H., Schober, K. and Oechtering, G. (2002): Echocardiographic reference values in West Highland White Terrier with special regard to right heart function (in German). Tierärztl. Prax. 30 , (K) 172–179.
Oechtering G. , 'Echocardiographic reference values in West Highland White Terrier with special regard to right heart function (in German) ' (2002 ) 30 Tierärztl. Prax. : 172 -179.
Bavegems, V., Duchateau, L., Stanislas, U. and De Rick, A. (2007): Echocardiographic reference values in Whippets. Vet. Radiol. Ultrasound 48 , 230–238.
Rick A. , 'Echocardiographic reference values in Whippets ' (2007 ) 48 Vet. Radiol. Ultrasound : 230 -238.
Belanger, M. C. (2005): Echocardiography. In: Ettinger, S. J. and Feldman, E. C. (eds) Textbook of Veterinary Internal Medicine. Diseases of the Dog and Cat. 6th edition. Elsevier Saunders, St. Louis, Missouri. pp. 331–326.
Belanger M. C. , '', in Textbook of Veterinary Internal Medicine. Diseases of the Dog and Cat , (2005 ) -.
Boon, J. A. (1998): Evaluation of size, function, and hemodynamics. In: Boon, J. A. (ed.) Manual of Veterinary Echocardiography. Williams & Wilkins, Baltimore. pp. 160–175.
Boon J. A. , '', in Manual of Veterinary Echocardiography , (1998 ) -.
Boon, J., Wingfield, W. E. and Miller, C. W. (1983): Echocardiographic indices in the normal dog. Vet. Radiol. 24 , 214–221.
Miller C. W. , 'Echocardiographic indices in the normal dog ' (1983 ) 24 Vet. Radiol. : 214 -221.
Bonagura, J. D. (1983): M-mode echocardiography: basic principles. Vet. Clin. North Am., Small Anim. Pract. 13 , 299–319.
Bonagura J. D. , 'M-mode echocardiography: basic principles ' (1983 ) 13 Vet. Clin. North Am., Small Anim. Pract. : 299 -319.
Bonagura, J. D. and Fuentes, V. L. (2000): Echocardiography. In: Ettinger, S. J. and Feldman, E. C. (eds) Textbook of Veterinary Internal Medicine. Diseases of the Dog and Cat. 5th edition. W. B. Saunders, Philadelphia. pp. 834–873.
Fuentes V. L. , '', in Textbook of Veterinary Internal Medicine. Diseases of the Dog and Cat , (2000 ) -.
Brown, D. J., Rush, J. E., MacGregor, J., Ross Jr., J. N., Brewer, B. and Rand, W. M. (2003): Mmode echocardiographic ratio indices in normal dogs, cats, and horses: a novel quantitative method. J. Vet. Intern. Med. 17 , 653–662.
Rand W. M. , 'Mmode echocardiographic ratio indices in normal dogs, cats, and horses: a novel quantitative method ' (2003 ) 17 J. Vet. Intern. Med. : 653 -662.
Child, J. S., Krivokapich, J. and Perloff, J. K. (1981): Effect of LV-size in mitral E point to ventricular septal separation in assessment of cardiac performance. Am. Heart J. 101 , 797–805.
Perloff J. K. , 'Effect of LV-size in mitral E point to ventricular septal separation in assessment of cardiac performance ' (1981 ) 101 Am. Heart J. : 797 -805.
Crippa, L., Ferro, E., Melloni, E., Brambrilla, P. and Cavaletti, E (1992): Echocardiographic parameters and indices in the normal Beagle dog. Lab. Anim. 26 , 190–195.
Cavaletti E. , 'Echocardiographic parameters and indices in the normal Beagle dog ' (1992 ) 26 Lab. Anim. : 190 -195.
Della Torre, P. K., Kirby, A. C., Church, D. B. and Malik, R. (2000): Echocardiographic measurements in Greyhounds, Whippets and Italian Greyhounds — dogs with a similar conformation but different size. Austr. Vet. J. 78 , 49–55.
Malik R. , 'Echocardiographic measurements in Greyhounds, Whippets and Italian Greyhounds — dogs with a similar conformation but different size ' (2000 ) 78 Austr. Vet. J. : 49 -55.
Gooding, J. P., Robinson, W. F. and Mews, G. C. (1986): Echocardiographic assessment of left ventricular dimensions in clinically normal English Cocker Spaniels. Am. J. Vet. Res. 47 , 296–300.
Mews G. C. , 'Echocardiographic assessment of left ventricular dimensions in clinically normal English Cocker Spaniels ' (1986 ) 47 Am. J. Vet. Res. : 296 -300.
Hansson, K., Häggström, J., Kvart, C. and Lord, P. (2002): Left atrial to aortic root indices using two-dimensional and M-mode echocardiography in Cavalier King Charles Spaniels with and without left atrial enlargement. Vet. Radiol. Ultrasound 43 , 568–575.
Lord P. , 'Left atrial to aortic root indices using two-dimensional and M-mode echocardiography in Cavalier King Charles Spaniels with and without left atrial enlargement ' (2002 ) 43 Vet. Radiol. Ultrasound : 568 -575.
Hetyey, Cs., Vörös, K. and Reiczigel, J. (2005): Comparison of two-dimensional echocardiographic measurements of the left atrium in healthy dogs. Acta Vet. Hung. 53 , 23–33.
Reiczigel J. , 'Comparison of two-dimensional echocardiographic measurements of the left atrium in healthy dogs ' (2005 ) 53 Acta Vet. Hung. : 23 -33.
Jacobs, G. and Mahjoob, K. (1988): Multiple regression analysis, using body size and cardiac cycle length in predicting echocardiographic variables in dogs. Am. J. Vet. Res. 49 , 1290–1294.
Mahjoob K. , 'Multiple regression analysis, using body size and cardiac cycle length in predicting echocardiographic variables in dogs ' (1988 ) 49 Am. J. Vet. Res. : 1290 -1294.
Kayar, A., Gonul, R., Or, M. E. and Uysal, A. (2006): M-mode echocardiographic parameters and indices in the normal German Shepherd dog. Vet. Radiol. Ultrasound 47 , 482–486.
Uysal A. , 'M-mode echocardiographic parameters and indices in the normal German Shepherd dog ' (2006 ) 47 Vet. Radiol. Ultrasound : 482 -486.
Kienle, R. D. and Thomas, W. P. (1995): Echocardiography, recommended methods for echocardiographic measurements. In: Nyland, T. G. and Mattoon, J. S. (eds) Veterinary Diagnostic Ultrasound. W. B. Saunders, Philadelphia. pp. 206–208.
Thomas W. P. , '', in Veterinary Diagnostic Ultrasound , (1995 ) -.
Kienle, R. D. and Thomas, W. P. (2002): Echocardiography. In: Nyland, T. G. and Mattoon, J. S. (eds) Small Animal Diagnostic Ultrasound. 2nd edition. W. B. Saunders, Philadelphia. pp. 354–424.
Thomas W. P. , '', in Small Animal Diagnostic Ultrasound , (2002 ) -.
Kirberger, R. M. (1991): Mitral valve E point to ventricular septal separation in the dog. J. S. Afr. Vet. Med. Assoc. 62 , 163–166.
Kirberger R. M. , 'Mitral valve E point to ventricular septal separation in the dog ' (1991 ) 62 J. S. Afr. Vet. Med. Assoc. : 163 -166.
Kosztolich, A. (1995): Clinical-cardiological Examinations of Mitral Valve Insufficiency in the Dog (in German). PhD Thesis. Vet.-Med. Univ., Wien.
Kosztolich, A. (1996): Clinical-cardiological examinations of mitral valve insufficiency in the dog (in German). Kleintierprax. 41 , 705–720.
Kosztolich A. , 'Clinical-cardiological examinations of mitral valve insufficiency in the dog (in German) ' (1996 ) 41 Kleintierprax : 705 -720.
Lombard, C. W. (1984): Normal values of the canine M-mode echocardiogram. J. Am. Vet. Med. Assoc. 185 , 988–992.
Lombard C. W. , 'Normal values of the canine M-mode echocardiogram ' (1984 ) 185 J. Am. Vet. Med. Assoc. : 988 -992.
Lonsdale, R. A., Labuc, R. H. and Robertson, I. D. (1998): Echocardiographic parameters in training compared with non-training dogs. Vet. Radiol. Ultrasound 39 , 325–330.
Robertson I. D. , 'Echocardiographic parameters in training compared with non-training dogs ' (1998 ) 39 Vet. Radiol. Ultrasound : 325 -330.
Mashiro, I., Nelson, R. R., Cohn, J. H. and Franciosa, J. A. (1976): Ventricular dimensions measured noninvasively by echocardiography in the awake dog. J. Appl. Physiol. 41 , 953–959
Franciosa J. A. , 'Ventricular dimensions measured noninvasively by echocardiography in the awake dog ' (1976 ) 41 J. Appl. Physiol. : 953 -959.
Morrison, S. A., Moise, N. S., Scarlett, J., Mohammed, H. and Yeager, A. E. (1992): Effect of breed and body weight on echocardiographic values in four breeds of dogs of differing somatotype. J. Vet. Intern. Med. 6 , 220–224.
Yeager A. E. , 'Effect of breed and body weight on echocardiographic values in four breeds of dogs of differing somatotype ' (1992 ) 6 J. Vet. Intern. Med. : 220 -224.
O’Grady, M. R., Bonagura, J. D., Powers, J. D. and Herring, D. S. (1986): Quantitative cross-sectional echocardiography in the normal dog. Vet. Radiol. 27 , 34–49.
Herring D. S. , 'Quantitative cross-sectional echocardiography in the normal dog ' (1986 ) 27 Vet. Radiol. : 34 -49.
Page, A., Edmunds, G. and Atwell, R. B. (1993): Echocardiographic values in the Greyhound. Aust. Vet. J. 70 , 361–364.
Atwell R. B. , 'Echocardiographic values in the Greyhound ' (1993 ) 70 Aust. Vet. J. : 361 -364.
Rishniw, M. and Erb, H. N. (2000): Evaluation of four 2-dimensional echocardiographic methods of assessing left atrial size in dogs. J. Vet. Intern. Med. 14 , 429–435.
Erb H. N. , 'Evaluation of four 2-dimensional echocardiographic methods of assessing left atrial size in dogs ' (2000 ) 14 J. Vet. Intern. Med. : 429 -435.
Sahn, D., Demaria, A., Kisslo, J. and Weymann, A. (1978): Recommendation regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 58 , 1072–1083.
Weymann A. , 'Recommendation regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements ' (1978 ) 58 Circulation : 1072 -1083.
Schober, K., Fuentes, V. E., Baade, H. and Oechtering, G. (2002): Echocardiographic reference values in Boxer dogs (in German). Tierärztl. Prax. 30 , 417–426.
Oechtering G. , 'Echocardiographic reference values in Boxer dogs (in German) ' (2002 ) 30 Tierärztl. Prax. : 417 -426.
Sisson, D. and Schauffer, D. (1991): Changes in linear dimensions of the heart, relative to body weight, as measured by M-mode echocardiography in growing dogs. Am. J. Vet. Res. 52 , 1591–1596.
Schauffer D. , 'Changes in linear dimensions of the heart, relative to body weight, as measured by M-mode echocardiography in growing dogs ' (1991 ) 52 Am. J. Vet. Res. : 1591 -1596.
Snyder, P. S., Sato, T. and Atkins, C. E. (1995): A comparison of echocardiographic indices of the nonracing healthy Greyhound to reference values from other breeds. Vet. Radiol. Ultrasound 36 , 387–392.
Atkins C. E. , 'A comparison of echocardiographic indices of the nonracing healthy Greyhound to reference values from other breeds ' (1995 ) 36 Vet. Radiol. Ultrasound : 387 -392.
Thomas, W. P. (1984): Two-dimensional, real-time echocardiography in the dog. Vet. Radiol. 25 , 50–64.
Thomas W. P. , 'Two-dimensional, real-time echocardiography in the dog ' (1984 ) 25 Vet. Radiol. : 50 -64.
Thomas, W. P., Gaber, C. E., Jacobs, G. J., Kaplan, P. M., Lombard, C. W., Moise, N. S. and Moses, B. L. (1993): Recommendations for standards in transthoracic two-dimensional echocardiography in the dog and cat. J. Vet. Intern. Med. 7 , 247–252.
Moses B. L. , 'Recommendations for standards in transthoracic two-dimensional echocardiography in the dog and cat ' (1993 ) 7 J. Vet. Intern. Med. : 247 -252.
Vollmar, A. (1999): Echocardiographic measurements in the Irish Wolfhound: reference values for the breed. J. Am. Anim. Hosp. Assoc. 35 , 271–277.
Vollmar A. , 'Echocardiographic measurements in the Irish Wolfhound: reference values for the breed ' (1999 ) 35 J. Am. Anim. Hosp. Assoc. : 271 -277.
Ware, W. A. (2007): Overview in echocardiography. In: Ware, W. A. (ed.): Cardiovascular Disease in Small Animal Medicine. Manson Publishing Ltd., London. pp. 68–90.
Ware W. A. , '', in Cardiovascular Disease in Small Animal Medicine , (2007 ) -.