Acta Veterinaria Hungarica
Volume/Issue:
Volume 57: Issue 3
Antimicrobial susceptibility of Pasteurella multocida isolated from swine and poultry
Authors: Boglárka Sellyei 1 , Zsuzsanna Varga 1 , Katalin Szentesi-Samu 2 , Éva Kaszanyitzky 2 , and Tibor Magyar 1
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  • 1 Veterinary Medical Research Institute of the Hungarian Academy of Sciences P.O. Box 18 H-1581 Budapest Hungary
  • 2 Veterinary Diagnostic Directorate Central Agricultural Office Budapest Hungary
DOI:
https://doi.org/10.1556/avet.57.2009.3.2
Page Count:
357–367
Publication Date:
01 Sep 2009
Online Publication Date:
27 Jul 2009
Article Category:
Research Article
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Pasteurella multocida causes infectious diseases in a wide range of animal species. Antimicrobial therapy is still an effective tool for treatment. Generally, P. multocida isolates are susceptible to most of the widely used commercial antimicrobial agents but their excessive and unjustified use accelerates the emergence of resistant strains. We defined the antimicrobial sensitivity pattern of 56 P. multocida strains isolated from poultry (20) and swine [16 P. multocida toxin (PMT) positive and 20 PMT negative] to 16 widely applied antibiotics (apramycin, cefquinome, chloramphenicol, colistin, doxycycline, enrofloxacin, erythromycin, florfenicol, flumequine, neomycin, oxolinic acid, penicillin, trimethoprim potentiated sulphamethoxazole, sulphonamide compounds, tetracycline, tulathromycin) by the disk diffusion method. The majority of the strains was susceptible to most of the antimicrobial agents tested. However, the resistance to sulphonamides, tetracyclines, first-generation quinolones and aminoglycosides was remarkable, and thus the use of these compounds for the treatment of infection caused by P. multocida is not recommended. On the other hand, the antimicrobial activity of the classical penicillin, the newer macrolide (tulathromycin), the third-generation fluoroquinolone (enrofloxacin) and the fourth-generation cephalosporin (cefquinome) proved to be satisfactory against this bacterium.

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Cover Acta Veterinaria Hungarica
Acta Veterinaria Hungarica
Print ISSN:
0236-6290
Online ISSN:
1588-2705
Keywords:
Pasteurella multocida ; swine; poultry; antibiotics

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