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  • 1 Szent István University Department of Obstetrics and Reproduction, Faculty of Veterinary Science István u. 2 H-1078 Budapest Hungary
  • 2 Awassi Corporation Bakonszeg Hungary
  • 3 University of Thessaly Clinic of Reproduction and Obstetrics, Veterinary Faculty Karditsa Greece
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The objective of this study was to evaluate the effect of long-term melatonin treatment applied during the non-breeding season on semen characteristics, endocrine function of testicles and baseline level of insulin-like growth factor-I (IGF-I) in Awassi rams kept in the temperate continental zone of Europe and used as semen donors in an artificial insemination (AI) programme. On 23 February (day 0), slow-release melatonin implants were inserted subcutaneously into rams (n = 8). Control animals (n = 8) received no treatment. In both groups, basic semen parameters (concentration, total motility, fast and slow forward motility, morphology), GnRH-induced testosterone response and basal IGF-I concentration were evaluated on days 0, 47 and 71. No differences were found in concentration of spermatozoa, total motility, and numbers of spermatozoa with fast and slow progressive motility and normal/abnormal morphology between the melatonin-treated and the control group. However, in melatonin-treated animals, basal and GnRH-induced testosterone levels were slightly elevated on day 47 and became significantly higher on day 71 (P < 0.05) as compared to controls. There was no difference in plasma IGF-I levels between the groups. In conclusion, slow-release melatonin applied during the non-breeding season improves testicular testosterone production but does not influence the semen characteristics and the IGF-I level of semen donor Awassi rams used in an AI programme and kept in the temperate continental zone of Europe.

  • Arendt, J. (1995): Physiology of the pineal: role in photoperiodic seasonal functions. In: Arendt, J. (ed.) Melatonin and the Mammalian Pineal Gland. Chapman & Hall, London. pp. 110–158.

    Arendt J. , '', in Melatonin and the Mammalian Pineal Gland , (1995 ) -.

  • Arendt, J., Symons, A. M., Laud, C. and Pryde, S. J. (1983): Melatonin can induce early onset of the breeding season in ewes. J. Endocrinol. 97 , 395–400.

    Pryde S. J. , 'Melatonin can induce early onset of the breeding season in ewes ' (1983 ) 97 J. Endocrinol. : 395 -400.

    • Search Google Scholar
  • Bourla, A. (1991): Effect of melatonin implants on the characteristics and on the freezability of Karagouniko rams’ semen. Ph.D. Thesis. Aristotle University of Thessaloniki, Greece.

    Bourla A. , '', in Effect of melatonin implants on the characteristics and on the freezability of Karagouniko rams’ semen , (1991 ) -.

    • Search Google Scholar
  • Casao, A., Vega, S., Palacin, I., Perez-Pe, R., Lavina, A., Quintin, F. J., Sevilla, E., Abecia, J. A., Cebrian-Perez, J. A., Forcada, F. and Muino-Blanco, T. (2008): Effects of melatonin implants during non-breeding season on sperm motility and reproductive parameters in Rasa Aragonesa rams. Reprod. Domest. Anim. Epub ahead of print, 15 October 2008. PMID 18954380.

  • Chemineau, P., Berthelot, X., Daveau, A., Maurice, F., Vignié, C. and Malpaux, B. (1993): Can melatonin be used in out of breeding season reproduction in domestic animals? Contracept. Fertil. Sex. 21 , 733–738.

    Malpaux B. , 'Can melatonin be used in out of breeding season reproduction in domestic animals? ' (1993 ) 21 Contracept. Fertil. Sex. : 733 -738.

    • Search Google Scholar
  • Chemineau, P., Daveau, A., Cognié, Y., Aumont, G. and Chesneau, D. (2004): Seasonal ovulatory activity exists in tropical Creole female goats and Black Belly ewes subjected to a temperate photoperiod. BMC Physiology 4 , 12–23.

    Chesneau D. , 'Seasonal ovulatory activity exists in tropical Creole female goats and Black Belly ewes subjected to a temperate photoperiod ' (2004 ) 4 BMC Physiology : 12 -23.

    • Search Google Scholar
  • Chemineau, P., Malpaux, B., Delgadillo, J. A., Guérin, Y., Ravault, J. P., Thimonier, J. and Pelletier, J. (1992): Control of sheep and goat reproduction: use of light and melatonin. Anim. Reprod. Sci. 30 , 157–184.

    Pelletier J. , 'Control of sheep and goat reproduction: use of light and melatonin ' (1992 ) 30 Anim. Reprod. Sci. : 157 -184.

    • Search Google Scholar
  • Chemineau, P., Pelletier, J., Guerin, Y., Colas, G., Ravault, J. P., Toure, G., Almeida, G., Thimonier, J. and Ortavant, R. (1998): Photoperiodic and melatonin treatments for the control of seasonal reproduction in sheep and goats. Reprod. Nutr. Dev. 28 , 409–422.

    Ortavant R. , 'Photoperiodic and melatonin treatments for the control of seasonal reproduction in sheep and goats ' (1998 ) 28 Reprod. Nutr. Dev. : 409 -422.

    • Search Google Scholar
  • Csernus, V. (1981): Antibodies of high affinity and specificity for radioimmunological determination of progesterone, testosterone and estradiol-17β. In: Advances in Steroid Analysis: Proceedings of the Symposium on the Analysis of Steroids. 20–22 May 1981, Eger, Hungary.

  • English, J., Poulton, A. L., Arendt, J. and Symons, A. M. (1986): A comparison of the efficiency of melatonin treatments in advancing oestrus in ewes. J. Reprod. Fertil. 77 , 321–327.

    Symons A. M. , 'A comparison of the efficiency of melatonin treatments in advancing oestrus in ewes ' (1986 ) 77 J. Reprod. Fertil. : 321 -327.

    • Search Google Scholar
  • Fitzgerald, J. A. and Stellflug, J. N. (1991): Effects of melatonin on seasonal changes in reproduction of rams. J. Anim. Sci. 69 , 264–275.

    Stellflug J. N. , 'Effects of melatonin on seasonal changes in reproduction of rams ' (1991 ) 69 J. Anim. Sci. : 264 -275.

    • Search Google Scholar
  • Karsch, G. J., Bittman, E. L., Foster, D. L., Goodman, R. L., Legan, S. J. and Robinson, J. (1984): Neuroendocrine basis of seasonal reproduction. Recent Prog. Horm. Res. 40 , 185–232.

    Robinson J. , 'Neuroendocrine basis of seasonal reproduction ' (1984 ) 40 Recent Prog. Horm. Res. : 185 -232.

    • Search Google Scholar
  • Kaya, A., Aksoy, M., Baspinar, N., Yildiz, C. and Ataman, M. B. (2001): Effect of melatonin implantation to sperm donor rams on post-thaw viability and acrosomal integrity of sperm cells in the breeding and non-breeding season. Reprod. Domest. Anim. 36 , 211–215.

    Ataman M. B. , 'Effect of melatonin implantation to sperm donor rams on post-thaw viability and acrosomal integrity of sperm cells in the breeding and non-breeding season ' (2001 ) 36 Reprod. Domest. Anim. : 211 -215.

    • Search Google Scholar
  • Kennaway, D. J. and Gilmore, T. A. (1985): Effects of melatonin implants in ram lambs. J. Reprod. Fertil. 73 , 85–91.

    Gilmore T. A. , 'Effects of melatonin implants in ram lambs ' (1985 ) 73 J. Reprod. Fertil. : 85 -91.

    • Search Google Scholar
  • Kokolis, N. A., Theodosiadou, E., Tsantarliotou, M., Rekkas, C., Goulas, P. and Smokovitis, A. (2000): The effect of melatonin implants on blood testosterone and acrosin activity in spermatozoa of the ram. Andrologia 32 , 107–114.

    Smokovitis A. , 'The effect of melatonin implants on blood testosterone and acrosin activity in spermatozoa of the ram ' (2000 ) 32 Andrologia : 107 -114.

    • Search Google Scholar
  • Kouimtzis, S. A., Belibasaki, S. and Doney, J. M. (1989): Melatonin advances and condenses the onset of seasonal breeding in Greek dairy ewes. Anim. Prod. 48 , 399–405.

    Doney J. M. , 'Melatonin advances and condenses the onset of seasonal breeding in Greek dairy ewes ' (1989 ) 48 Anim. Prod. : 399 -405.

    • Search Google Scholar
  • Leitold, J., Hinger, S., Kulcsár, M. and Huszenicza, Gy. (2004): Antler deformity and its surgical removal in a castrated roebuck ( Capreolus capreolus L.). Magyar Állatorvosok Lapja 126 , 231–236.

    Huszenicza Gy. , 'Antler deformity and its surgical removal in a castrated roebuck (Capreolus capreolus L.) ' (2004 ) 126 Magyar Állatorvosok Lapja : 231 -236.

    • Search Google Scholar
  • Lincoln, G. A. (1994): Effects of placing micro-implants of melatonin in the pars tuberalis, pars distalis and the lateral septum of the forebrain on the secretion of FSH and prolactin, and testicular size in rams. J. Endocrinol. 142 , 267–276.

    Lincoln G. A. , 'Effects of placing micro-implants of melatonin in the pars tuberalis, pars distalis and the lateral septum of the forebrain on the secretion of FSH and prolactin, and testicular size in rams ' (1994 ) 142 J. Endocrinol. : 267 -276.

    • Search Google Scholar
  • Lincoln, G. A. and Ebling, F. J. P. (1985): Effect of constant-release implants of melatonin on seasonal cycles in reproduction, prolactin secretion and moulting in rams. J. Reprod. Fertil. 73 , 241–253.

    Ebling F. J. P. , 'Effect of constant-release implants of melatonin on seasonal cycles in reproduction, prolactin secretion and moulting in rams ' (1985 ) 73 J. Reprod. Fertil. : 241 -253.

    • Search Google Scholar
  • Lincoln, G. A. and Kelly, R. W. (1989): Test of ML23 as an antagonist to the effects of melatonin in the ram. J. Reprod. Fertil. 86 , 737–743.

    Kelly R. W. , 'Test of ML23 as an antagonist to the effects of melatonin in the ram ' (1989 ) 86 J. Reprod. Fertil. : 737 -743.

    • Search Google Scholar
  • Lincoln, G. A., Almeida, O. F. X., Klandorf, H. and Cunningham, R. A. (1982): Hourly fluctuations in the blood levels of melatonin, prolactin, luteinizing hormone, follicle-stimulating hormone, testosterone, triiodothyronine, thyroxine and cortisol in rams under artificial photoperiods and the effect of cranial sympathectomy. J. Endocrinol. 92 , 237–250.

    Cunningham R. A. , 'Hourly fluctuations in the blood levels of melatonin, prolactin, luteinizing hormone, follicle-stimulating hormone, testosterone, triiodothyronine, thyroxine and cortisol in rams under artificial photoperiods and the effect of cranial sympathectomy ' (1982 ) 92 J. Endocrinol. : 237 -250.

    • Search Google Scholar
  • Lindsay, D. R., Pelletier, J., Pisselet, C. and Courot, M. (1984): Changes in photoperiod and nutrition and their effect on testicular growth of rams. J. Reprod. Fertil. 71 , 351–356.

    Courot M. , 'Changes in photoperiod and nutrition and their effect on testicular growth of rams ' (1984 ) 71 J. Reprod. Fertil. : 351 -356.

    • Search Google Scholar
  • Mabjeesh, S. J., Gal-Garber, O. and Shamay, A. (2007): Effect of photoperiod in the third trimester of gestation on milk production and circulating hormones in dairy goats. J. Dairy Sci. 90 , 699–705.

    Shamay A. , 'Effect of photoperiod in the third trimester of gestation on milk production and circulating hormones in dairy goats ' (2007 ) 90 J. Dairy Sci. : 699 -705.

    • Search Google Scholar
  • Pelletier, J. and Ortavant, R. (1975 a ): Photoperiodic control of LH release in the ram. I. Influence of increasing and decreasing light photoperiods. Acta Endocrinol. (Copenhagen) 78 , 435–441.

    Ortavant R. , 'Photoperiodic control of LH release in the ram. I. Influence of increasing and decreasing light photoperiods ' (1975 ) 78 Acta Endocrinol. (Copenhagen) : 435 -441.

    • Search Google Scholar
  • Pelletier, J. and Ortavant, R. (1975 b ): Photoperiodic control of LH release in the ram. II. Lightandrogens interaction. Acta Endocrinol. (Copenhagen) 78 , 442–450.

    Ortavant R. , 'Photoperiodic control of LH release in the ram. II. Lightandrogens interaction ' (1975 ) 78 Acta Endocrinol. (Copenhagen) : 442 -450.

    • Search Google Scholar
  • Ramadan, T. A., Taha, T. A., Samak, M. A. and Hassan, A. (2009): Effectiveness of exposure to longday followed by melatonin treatment on semen characteristics of Damascus male goats during breeding and non-breeding seasons. Theriogenology 71 , 458–468.

    Hassan A. , 'Effectiveness of exposure to longday followed by melatonin treatment on semen characteristics of Damascus male goats during breeding and non-breeding seasons ' (2009 ) 71 Theriogenology : 458 -468.

    • Search Google Scholar
  • Rosa, H. J. D., Juniper, D. T. and Bryant, M. J. (2000): Effects of recent sexual experience and melatonin treatment of rams on plasma testosterone concentration, sexual behaviour and ability to induce ovulation in seasonally anoestrous ewes. J. Reprod. Fert. 120 , 169–176.

    Bryant M. J. , 'Effects of recent sexual experience and melatonin treatment of rams on plasma testosterone concentration, sexual behaviour and ability to induce ovulation in seasonally anoestrous ewes ' (2000 ) 120 J. Reprod. Fert. : 169 -176.

    • Search Google Scholar
  • Stellflug, J. N., Fitzgerald, J. A., Parker, C. F. and Bolt, D. (1988): Influence of concentration, duration and route of administration of melatonin on reproductive performance of springmated Polypay and Polypay-cross ewes. J. Anim. Sci. 66 , 1855–1863.

    Bolt D. , 'Influence of concentration, duration and route of administration of melatonin on reproductive performance of springmated Polypay and Polypay-cross ewes ' (1988 ) 66 J. Anim. Sci. : 1855 -1863.

    • Search Google Scholar
  • Schatten, H. and Constantinescu, G. M. (2007): Comparative Reproductive Biology. Blackwell Publishing, Oxford, UK. pp. 117–133.

    Constantinescu G. M. , '', in Comparative Reproductive Biology , (2007 ) -.

  • Tsantarliotou, M., Kokolis, N. A. and Smokovitis, A. (2008): Melatonin administration increased plasminogen activator activity in ram spermatozoa. Theriogenology 69 , 458–465.

    Smokovitis A. , 'Melatonin administration increased plasminogen activator activity in ram spermatozoa ' (2008 ) 69 Theriogenology : 458 -465.

    • Search Google Scholar
  • Tsiligianni, T. H., Cseh, S., Valasi, I., Faigl, V., Varinas, E., Samanti, F. and Amiridis, G. S. (2009): Effects of melatonin treatment on follicular development and oocyte quality in Chios ewes. Acta Vet. Hung. 57 , 331–335.

    Amiridis G. S. , 'Effects of melatonin treatment on follicular development and oocyte quality in Chios ewes ' (2009 ) 57 Acta Vet. Hung. : 331 -335.

    • Search Google Scholar

 

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