Acta Veterinaria Hungarica
Volume/Issue:
Volume 58: Issue 4
Vertebral osteomyelitis and meningomyelitis caused by Pasteurella canis in a dog — Clinicopathological case report
Authors: Péter Csébi 1 , Csaba Jakab 2 , Katalin Jánosi 3 , Boglárka Sellyei 5 , Tamás Ipolyi 1 , Zoltán Szabó 4 , Attila Arany-Tóth 1 , and Tibor Németh 1
View More View Less
  • 1 Faculty of Veterinary Science, Szent István University Department and Clinic of Surgery and Ophthalmology István utca 2 H-1078 Budapest Hungary
  • 2 Faculty of Veterinary Science, Szent István University István utca 2 H-1078 Budapest Hungary
  • 3 Faculty of Veterinary Science, Szent István University István utca 2 H-1078 Budapest Hungary
  • 4 Faculty of Veterinary Science, Szent István University István utca 2 H-1078 Budapest Hungary
  • 5 Veterinary Medical Research Institute of the Hungarian Academy of Sciences Hungária krt. 21 H-1143 Budapest Hungary
DOI:
https://doi.org/10.1556/avet.58.2010.4.2
Page Count:
413–421
Publication Date:
01 Dec 2010
Online Publication Date:
18 Nov 2010
Article Category:
Research Article
Restricted access

Purchase article

USD  $25.00

1 year subscription (Individual Only)

USD  $836.00
Purchase Online Subscription

  • Purchase article

    USD  $25.00

  • 1 year subscription (Individual Only)

    USD  $836.00

A clinicopathological case study of vertebral osteomyelitis caused by Pasteurella canis in a 2.5-year-old male Jack Russell Terrier is presented. The case was characterised by a chronic course with signs of spinal pain and acute paraplegia. The diagnosis was established by radiography, myelography, post-myelographic CT examination, and laboratory tests including routine blood work and cerebrospinal fluid (CSF) cytology, and confirmed by postmortem pathological and microbiological examinations. Diagnostic imaging showed severe osteolysis, ventral spondylosis and spinal cord compression at the 4th and 5th lumbar vertebrae. The blood tests revealed mild leukocytosis and anaemia, while CSF cytology showed lymphocytic and mononuclear pleocytosis. Necropsy demonstrated severe osteomyelitis and meningomyelitis, but the source of infection could not be established. To the authors’ knowledge, this is the first description of canine vertebral osteomyelitis caused by this organism.

  • Adamo, P. F. and Cherubini, G. B. (2001): Discospondylitis associated with three unreported bacteria in the dog. J. Small Anim. Pract. 42 , 352–355.

    Cherubini G. B. , 'Discospondylitis associated with three unreported bacteria in the dog ' (2001 ) 42 J. Small Anim. Pract. : 352 -355.

    • Search Google Scholar

  • Allison, K. and Clarridge, J. E. (2005): Long-term respiratory tract infection with canine-associated Pasteurella dagmatis and Neisseria canis in a patient with chronic bronchiectasis. J. Clin. Microbiol. 43 , 4272–4274.

    Clarridge J. E. , 'Long-term respiratory tract infection with canine-associated Pasteurella dagmatis and Neisseria canis in a patient with chronic bronchiectasis ' (2005 ) 43 J. Clin. Microbiol. : 4272 -4274.

    • Search Google Scholar

  • Barrow, G. I. and Feltham, R. K. A. (1993): Cowan and Steel’s Manual for the Identification of Medical Bacteria. Third edition. Cambridge University Press, New York, USA.

    Feltham R. K. A. , '', in Cowan and Steel’s Manual for the Identification of Medical Bacteria , (1993 ) -.

  • Baldrias, L., Frost, A. J. and O’Boyle, D. (1988): The isolation of Pasteurella -like organisms from tonsillar region of dogs and cats. J. Small Anim. Pract. 29 , 63–68.

    O’Boyle D. , 'The isolation of Pasteurella-like organisms from tonsillar region of dogs and cats ' (1988 ) 29 J. Small Anim. Pract. : 63 -68.

    • Search Google Scholar

  • Bradney, I. W. (1985): Vertebral osteomyelitis due to Nocardia in a dog. Aust. Vet. J. 62 , 315–316.

    Bradney I. W. , 'Vertebral osteomyelitis due to Nocardia in a dog ' (1985 ) 62 Aust. Vet. J. : 315 -316.

    • Search Google Scholar

  • Dunbar, M. and Vulgamott, J. C. (1981): Thoracic and vertebral osteomyelitis caused by actinomycosis in a dog. Vet. Med. Small Anim. Clin. 76 , 1159–1161.

    Vulgamott J. C. , 'Thoracic and vertebral osteomyelitis caused by actinomycosis in a dog ' (1981 ) 76 Vet. Med. Small Anim. Clin. : 1159 -1161.

    • Search Google Scholar

  • Dupuy, O., Garrabé, E., Bordier, L., Boyer, B., Goasguen, O., Mayaudon, H. and Bauduceau, B. (2006): Pasteurella dagmatis spondylodiscitis in a diabetic patient (in French). Rev. Med. Intern. 27 , 803–804.

    Bauduceau B. , 'Pasteurella dagmatis spondylodiscitis in a diabetic patient (in French) ' (2006 ) 27 Rev. Med. Intern. : 803 -804.

    • Search Google Scholar

  • Fajfar-Whetstone, C. J., Coleman, L., Biggs, D. R. and Fox, B. C. (1995): Pasteurella multocida septicemia and subsequent Pasteurella dagmatis septicemia in a diabetic patient. J. Clin. Microbiol. 33 , 202–204.

    Fox B. C. , 'Pasteurella multocida septicemia and subsequent Pasteurella dagmatis septicemia in a diabetic patient ' (1995 ) 33 J. Clin. Microbiol. : 202 -204.

    • Search Google Scholar

  • Frederiksen, W. (1973): Pasteurella taxonomy and nomenclature. Contr. Microbiol. Immunol. 2 , 170–176.

    Frederiksen W. , 'Pasteurella taxonomy and nomenclature ' (1973 ) 2 Contr. Microbiol. Immunol. : 170 -176.

    • Search Google Scholar

  • Garcia-Hejl, C., Bigaillon, C., Garcia, C., Dupuy, O., Gros, C., Garrabe, E. and Cavallo, J. D. (2007): Pasteurella dagmatis : an unusual cause of vertebral osteomyelitis (in French). Pathol. Biol. (Paris) 55 , 340–342.

    Cavallo J. D. , 'Pasteurella dagmatis: an unusual cause of vertebral osteomyelitis (in French) ' (2007 ) 55 Pathol. Biol. (Paris) : 340 -342.

    • Search Google Scholar

  • Gautier, A-L., Dubois, D., Escande, F., Avril, J-L., Trieu-Cuot, P. and Gaillot, O. (2005): Rapid and accurate identification of human isolates of Pasteurella and related species by sequencing the sodA gene. J. Clin. Microbiol. 43 , 2307–2314.

    Gaillot O. , 'Rapid and accurate identification of human isolates of Pasteurella and related species by sequencing the sodA gene ' (2005 ) 43 J. Clin. Microbiol. : 2307 -2314.

    • Search Google Scholar

  • Hara, H., Ochiai, T., Morishima, T., Arashima, Y., Kumasaka, K. and Kawano, K. Y. (2002): Pasteurella canis osteomyelitis and cutaneous abscess after a domestic dog bite. J. Am. Acad. Dermatol. 46 , 151–152.

    Kawano K. Y. , 'Pasteurella canis osteomyelitis and cutaneous abscess after a domestic dog bite ' (2002 ) 46 J. Am. Acad. Dermatol. : 151 -152.

    • Search Google Scholar

  • Jerram, R. M. and Dewey, C. W. (1998): Suspected spinal epidural empyema and associated vertebral osteomyelitis (physitis) in a dog. J. Vet. Emerg. Crit. Care 8 , 103–108.

    Dewey C. W. , 'Suspected spinal epidural empyema and associated vertebral osteomyelitis (physitis) in a dog ' (1998 ) 8 J. Vet. Emerg. Crit. Care : 103 -108.

    • Search Google Scholar

  • Johnston, D. E. and Summers, B. A. (1971): Osteomyelitis of the lumbar vertebrae in dogs caused by grass-seed foreign bodies. Aust. Vet. J. 47 , 289–294.

    Summers B. A. , 'Osteomyelitis of the lumbar vertebrae in dogs caused by grass-seed foreign bodies ' (1971 ) 47 Aust. Vet. J. : 289 -294.

    • Search Google Scholar

  • Mitten, R. W. (1974): Vertebral osteomyelitis in the dog due to Nocardia -like organisms. J. Small Anim. Pract. 15 , 563–570.

    Mitten R. W. , 'Vertebral osteomyelitis in the dog due to Nocardia-like organisms ' (1974 ) 15 J. Small Anim. Pract. : 563 -570.

    • Search Google Scholar

  • Moore, M. P. (1992): Discospondylitis. Vet. Clin. North Am.: Small Anim. Pract. 22 , 1027–1034.

    Moore M. P. , 'Discospondylitis ' (1992 ) 22 Vet. Clin. North Am.: Small Anim. Pract. : 1027 -1034.

    • Search Google Scholar

  • Murphy, E. (2008): Microbiology of animal bites. Clinical Microbiology Newsletter 30 , 47–50.

    Murphy E. , 'Microbiology of animal bites ' (2008 ) 30 Clinical Microbiology Newsletter : 47 -50.

    • Search Google Scholar

  • Mutters, R., Ihm, P., Pohl, S., Frederiksen, W. and Mannheim, W. (1985): Reclassification of the genus Pasteurella Trevisan 1887 on the basis of deoxyribonucleic acid homology, with proposals for the new species Pasteurella dagmatis, Pasteurella canis, Pasteurella stomatis, Pasteurella anatis , and Pasteurella langaa . Int. J. Syst. Bacteriol. 35 , 309–322.

    Mannheim W. , 'Reclassification of the genus Pasteurella Trevisan 1887 on the basis of deoxyribonucleic acid homology, with proposals for the new species Pasteurella dagmatis, Pasteurella canis, Pasteurella stomatis, Pasteurella anatis, and Pasteurella langaa ' (1985 ) 35 Int. J. Syst. Bacteriol. : 309 -322.

    • Search Google Scholar

  • Platt, S. R. (2004): Neck and back pain. In: Platt, S. R. and Olby, N. J. (eds) BSAVA Manual of Canine and Feline Neurology. Third edition. BSAVA, Gloucester. pp. 210–212.

    Platt S. R. , '', in BSAVA Manual of Canine and Feline Neurology , (2004 ) -.

  • Puente Redondo, V. A., Gutierrez Martin, C. B., Garcia del Blanco, N., Antolín Ayala, M. I., Alonso Alonso, P. and Rodríguez Ferri, E. F. (2000): Systemic infection by Pasteurella canis biotype 1 in newborn puppies. J. Comp. Path. 123 , 195–197.

    Rodríguez Ferri E. F. , 'Systemic infection by Pasteurella canis biotype 1 in newborn puppies ' (2000 ) 123 J. Comp. Path. : 195 -197.

    • Search Google Scholar

  • Schwartz, M., Boettcher, I. C., Kramer, S. and Tipold, A. (2009): Two dogs with iatrogenic discospondylitis caused by methicillin-resistant Staphylococcus aureus : A case report. J. Small Anim. Pract. 50 , 201–205.

    Tipold A. , 'Two dogs with iatrogenic discospondylitis caused by methicillin-resistant Staphylococcus aureus: A case report ' (2009 ) 50 J. Small Anim. Pract. : 201 -205.

    • Search Google Scholar

  • Seim, H. B. (2007): Nonsurgical diseases of the spine. In: Fossum, T. W. (ed.) Small Animal Surgery. Third edition. Mosby, St. Louis. pp. 1514–1517.

    Seim H. B. , '', in Small Animal Surgery , (2007 ) -.

  • Sellyei, B., Wehmann, E., Makrai, L. and Magyar, T. (2010): Characterisation of Pasteurella dagmatis -like isolates recovered from the feline oral cavity. Vet. Microbiol. (in press; available online 27 March 2010; doi: 10.1016/j.vetmic.2010.03.022).

  • Smith, J. E. (1961): The aerobic bacteria of the nose and tonsils of healthy dogs. J. Comp. Pathol. 71 , 428–433.

    Smith J. E. , 'The aerobic bacteria of the nose and tonsils of healthy dogs ' (1961 ) 71 J. Comp. Pathol. : 428 -433.

    • Search Google Scholar

  • Soda, T., Ogura, K., Ishitogu, S., Niibayashi, H. and Yoshida, O. (2007): Pyogenic vertebral osteomyelitis after acute bacterial prostatitis: A case report. Int. J. Urol. 3 , 402–404.

    Yoshida O. , 'Pyogenic vertebral osteomyelitis after acute bacterial prostatitis: A case report ' (2007 ) 3 Int. J. Urol. : 402 -404.

    • Search Google Scholar

  • Talan, D. A., Citron, D. M., Abrahamion, F. M., Moran, G. J. and Goldstein, E. J. C. (1999): Bacteriologic analysis of infected dog and cat bites. The New England J. of Med. 340 , 85–92.

    Goldstein E. J. C. , 'Bacteriologic analysis of infected dog and cat bites ' (1999 ) 340 The New England J. of Med. : 85 -92.

    • Search Google Scholar

  • Thomas, W. B. (2000): Discospondylitis and other vertebral infections. Vet. Clin. North Am.: Small Anim. Pract. 30 , 169–181.

    Thomas W. B. , 'Discospondylitis and other vertebral infections ' (2000 ) 30 Vet. Clin. North Am.: Small Anim. Pract. : 169 -181.

    • Search Google Scholar
Cover Acta Veterinaria Hungarica
Acta Veterinaria Hungarica
Print ISSN:
0236-6290
Online ISSN:
1588-2705
Keywords:
Dog; vertebral osteomyelitis; Pasteurella canis

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Sep 2020 9 1 2
Oct 2020 1 0 0
Nov 2020 8 0 0
Dec 2020 0 0 0
Jan 2021 16 2 2
Feb 2021 6 0 0
Mar 2021 0 0 0