View More View Less
  • 1 Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences Division of Reproductive Biology Tuwima 10 10-748 Olsztyn Poland
  • | 2 University of Warmia and Mazury Department of Human Physiology Olsztyn Poland
  • | 3 University of Warmia and Mazury Department of Neurology and Neurosurgery, Faculty of Medical Sciences Olsztyn Poland
Restricted access

Purchase article

USD  $25.00

1 year subscription (Individual Only)

USD  $836.00

Previously, we have shown that the activity of noradrenergic nerve fibres increased and the steroid content changed in porcine ovaries with dexamethasone-(DXM-) induced polycystic status. To better understand the role of the ovarian nerves in the formation of cystic status, the morphology and steroidogenic activity of the ovaries of DXM-treated gilts after denervation of the gonads were investigated in this study. Ovarian denervation was performed on day 3 of the first studied oestrous cycle and then, on days 7–21 of the cycle, DXM was administered. Following neurectomy and DXM treatment, cysts, medium-sized follicles and corpora lutea were not present, while the number of small-sized follicles increased. Denervation and DXM application led to a reduction in the number of dopamine-β-hydroxylase- and/or neuropeptide Y-immunoreactive nerve fibres. The concentrations of progesterone, androstenedione, testosterone and oestradiol-17β in the follicular fluid and/or in the wall of small-sized follicles of the experimental gilts were lower than in the controls. A similar result was demonstrated for P450scc, 3β-HSD and P450arom protein contents in the small follicles. Our data showed that DXM was not able to stimulate the formation of cysts in denervated porcine ovaries, indicating that the ovarian peripheral nerves might participate in the aetiopathogenesis of polycystic status.

  • Baranowska, B., Chmielowska, M., Radzikowska, M., Borowiec, M., Rogulski, K. and Wasilewska-Dziubinska, E. (1999): Effects of neuropeptide Y (NPY), galanin and vasoactive intestinal peptide (VIP) on pituitary hormone release and ovarian steroidogenesis. Neurol. Endocrinol. Lett. 20, 385–389.

    Wasilewska-Dziubinska E. , 'Effects of neuropeptide Y (NPY), galanin and vasoactive intestinal peptide (VIP) on pituitary hormone release and ovarian steroidogenesis ' (1999 ) 20 Neurol. Endocrinol. Lett. : 385 -389.

    • Search Google Scholar
  • Barria, A., Leyton, V., Ojeda, S. and Lara, H. (1993): Ovarian steroidal response to gonadotropins and beta-adrenergic stimulation enhanced in polycystic ovary syndrome: role of sympathetic innervation. Endocrinology 133, 2696–2703.

    Lara H. , 'Ovarian steroidal response to gonadotropins and beta-adrenergic stimulation enhanced in polycystic ovary syndrome: role of sympathetic innervation ' (1993 ) 133 Endocrinology : 2696 -2703.

    • Search Google Scholar
  • Burden, H. and Lawrence, I. (1977): The effects of denervation on the localization of delta5-3betahydroxysteroid dehydrogenase activity in the rat ovary during pregnancy. Acta Anat. 97, 286–290.

    Lawrence I. , 'The effects of denervation on the localization of delta5-3betahydroxysteroid dehydrogenase activity in the rat ovary during pregnancy ' (1977 ) 97 Acta Anat. : 286 -290.

    • Search Google Scholar
  • Dziadkowiec, J., Danilczuk, H. and Rembiesa, R. (1982a): Biosynthesis of progesterone in rat placenta. Endokrynol. Pol. 33, 201–207.

    Rembiesa R. , 'Biosynthesis of progesterone in rat placenta ' (1982 ) 33 Endokrynol. Pol. : 201 -207.

    • Search Google Scholar
  • Dziadkowiec, J., Warchoł, A. and Rembiesa, R. (1982b): Biosynthesis of estrogens in pregnant rats. Endokrynol. Pol. 33, 4–6.

    Rembiesa R. , 'Biosynthesis of estrogens in pregnant rats ' (1982 ) 33 Endokrynol. Pol. : 4 -6.

    • Search Google Scholar
  • Hotchkiss, J., Aitkinson, L. E. and Knobil, E. (1971): Time course of serum estrogen and luteinizing hormone (LH) concentration during the menstrual cycle of the rhesus monkey. Endocrinology 89, 177–183.

    Knobil E. , 'Time course of serum estrogen and luteinizing hormone (LH) concentration during the menstrual cycle of the rhesus monkey ' (1971 ) 89 Endocrinology : 177 -183.

    • Search Google Scholar
  • Huang, T-J. and Li, P. (2001): Dexamethasone inhibits luteinizing hormone-induced synthesis of steroidogenic acute regulatory protein in cultured rat preovulatory follicles. Biol. Reprod. 64, 163–170.

    Li P. , 'Dexamethasone inhibits luteinizing hormone-induced synthesis of steroidogenic acute regulatory protein in cultured rat preovulatory follicles ' (2001 ) 64 Biol. Reprod. : 163 -170.

    • Search Google Scholar
  • Jana, B. and Majewski, M. (2007): Influence of the peripheral nervous system on ovarian function (in Polish). Med. Wet. 63, 1163–1167.

    Majewski M. , 'Influence of the peripheral nervous system on ovarian function (in Polish) ' (2007 ) 63 Med. Wet. : 1163 -1167.

    • Search Google Scholar
  • Jana, B., Dzienis, A., Pańczyszyn, J., Rogozińska, A., Wojtkiewicz, J., Skobowiat, C. and Majewski, M. (2005a): Denervation of the porcine ovaries performed during the early luteal phase influenced morphology and function of the gonad. Reprod. Biol. 1, 69–82.

    Majewski M. , 'Denervation of the porcine ovaries performed during the early luteal phase influenced morphology and function of the gonad ' (2005 ) 1 Reprod. Biol. : 69 -82.

    • Search Google Scholar
  • Jana, B., Dzienis, A., Rogozińska, A., Piskuła, M., Jedlinska-Krakowska, M., Wojtkiewicz, J. and Majewski, M. (2005b): Dexamethasone-induced changes in sympathetic innervation of porcine ovaries and in their steroidogenic activity. J. Reprod. Dev. 6, 715–725.

    Majewski M. , 'Dexamethasone-induced changes in sympathetic innervation of porcine ovaries and in their steroidogenic activity ' (2005 ) 6 J. Reprod. Dev. : 715 -725.

    • Search Google Scholar
  • Jana, B., Dzienis, A., Wojtkiewicz, J., Kaczmarek, M. and Majewski, M. (2007): Surgical denervation of porcine ovaries during the middle luteal phase of the oestrous cycle changes their morphology and steroidogenic activity. Acta Vet. Hung. 55, 107–122.

    Majewski M. , 'Surgical denervation of porcine ovaries during the middle luteal phase of the oestrous cycle changes their morphology and steroidogenic activity ' (2007 ) 55 Acta Vet. Hung. : 107 -122.

    • Search Google Scholar
  • Jana, B., Kozłowska, A., Andronowska, A. and Jedlińska-Krakowska, M. (2008): The effect of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β and IL-6 on chorioamnion secretion of prostaglandins (PG)F2α and E2 in pigs. Reprod. Biol. 8, 57–68.

    Jedlińska-Krakowska M. , 'The effect of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β and IL-6 on chorioamnion secretion of prostaglandins (PG)F2α and E2 in pigs ' (2008 ) 8 Reprod. Biol. : 57 -68.

    • Search Google Scholar
  • Karalus, U., Downey, B. and Ainsworth, L. (1990): Maintenance of ovulatory cycles and pregnancy in prepubertal gilts treated with PMSG and hCG. Anim. Reprod. Sci. 22, 235–241.

    Ainsworth L. , 'Maintenance of ovulatory cycles and pregnancy in prepubertal gilts treated with PMSG and hCG ' (1990 ) 22 Anim. Reprod. Sci. : 235 -241.

    • Search Google Scholar
  • Kawate, N., Inaba, T. and Mori, J. (1993): Effects of cortisol on the amounts of estradiol-17β and progesterone secreted and the number of luteinizing hormone receptors in cultured bovine granulosa cells. Anim. Reprod. Sci. 32, 15–25.

    Mori J. , 'Effects of cortisol on the amounts of estradiol-17β and progesterone secreted and the number of luteinizing hormone receptors in cultured bovine granulosa cells ' (1993 ) 32 Anim. Reprod. Sci. : 15 -25.

    • Search Google Scholar
  • Kotwica, J. and Williams, G. L. (1982): Relationship of plasma testosterone concentrations to pituitary-ovarian hormone secretion during the bovine estrous cycle and the effects of testosterone propionate administration during luteal regression. Biol. Reprod. 27, 790–801.

    Williams G. L. , 'Relationship of plasma testosterone concentrations to pituitary-ovarian hormone secretion during the bovine estrous cycle and the effects of testosterone propionate administration during luteal regression ' (1982 ) 27 Biol. Reprod. : 790 -801.

    • Search Google Scholar
  • Kozłowska, A. (2009): The innervation and steroidogenic activity of cystic ovaries of pigs (in Polish). PhD Thesis. IRZiBŻ PAN, Olsztyn.

    Kozłowska A. , '', in The innervation and steroidogenic activity of cystic ovaries of pigs (in Polish) , (2009 ) -.

  • Kozłowska, A., Majewski, M. and Jana, B. (2009): Expression of steroidogenic enzymes in porcine polycystic ovaries. Folia Histochem. Cytobiol. 47, 257–264.

    Jana B. , 'Expression of steroidogenic enzymes in porcine polycystic ovaries ' (2009 ) 47 Folia Histochem. Cytobiol. : 257 -264.

    • Search Google Scholar
  • Kozłowska, A., Wojtkiewicz, J., Majewski, M. and Jana, B. (2011): Localization of substance P, calcitonin gene related peptide and galanin in the nerve fibres of porcine cystic ovaries. Folia Histochem. Cytobiol. 49, 622–630.

    Jana B. , 'Localization of substance P, calcitonin gene related peptide and galanin in the nerve fibres of porcine cystic ovaries ' (2011 ) 49 Folia Histochem. Cytobiol. : 622 -630.

    • Search Google Scholar
  • Lawrence, I. and Burden, H. (1980): The origin of the extrinsic adrenergic innervation to the rat ovary. Anat. Rec. 196, 51–59.

    Burden H. , 'The origin of the extrinsic adrenergic innervation to the rat ovary ' (1980 ) 196 Anat. Rec. : 51 -59.

    • Search Google Scholar
  • Majewski, M. and Heym, C. (1991): The origin of ovarian neuropeptide Y (NPY)-immunoreactive nerve fibres from the inferior mesenteric ganglion in the pig. Cell Tissue Res. 266, 591–596.

    Heym C. , 'The origin of ovarian neuropeptide Y (NPY)-immunoreactive nerve fibres from the inferior mesenteric ganglion in the pig ' (1991 ) 266 Cell Tissue Res. : 591 -596.

    • Search Google Scholar
  • Morales-Ledesma, L., Linares, R., Rosas, G., Morán, C., Chavira, R., Cárdenas, M. and Domínguez, R. (2010): Unilateral sectioning of the superior ovarian nerve of rats with polycystic ovarian syndrome restores ovulation in the innervated ovary. Reprod. Biol. Endocrinol. 8, 99. doi: 10.1186/1477-7827-8-99.

    Domínguez R. , 'Unilateral sectioning of the superior ovarian nerve of rats with polycystic ovarian syndrome restores ovulation in the innervated ovary ' (2010 ) 8 Reprod. Biol. Endocrinol. : 99 -.

    • Search Google Scholar
  • Myrsen, U., Ahren, B. and Sundler, F. (1996): Dexamethasone-induced neuropeptide Y expression in rat islet endocrine cells. Rapid reversibility and partial prevention by insulin. Diabetes 45, 1306–1316.

    Sundler F. , 'Dexamethasone-induced neuropeptide Y expression in rat islet endocrine cells ' (1996 ) 45 Rapid reversibility and partial prevention by insulin. Diabetes : 1306 -1316.

    • Search Google Scholar
  • Nakamura, Y. (1990): Treatment of polycystic ovary syndrome: an overview. Horm. Res. 33(Suppl. 2), 31.

    Nakamura Y. , 'Treatment of polycystic ovary syndrome: an overview ' (1990 ) 33 Horm. Res. : 31 -.

    • Search Google Scholar
  • Rosa-e-Silva, A. A., Prajiante, T. M., Almeida, F. H., Guimaraes, M. A. and Lunardi, L. O. (1997): Ovarian granulosa and theca interstitial cells: a morphological and physiological analysis in guanethidine denervated rats at pre-puberty. Cell. Mol. Biol. 43, 409–416.

    Lunardi L. O. , 'Ovarian granulosa and theca interstitial cells: a morphological and physiological analysis in guanethidine denervated rats at pre-puberty ' (1997 ) 43 Cell. Mol. Biol. : 409 -416.

    • Search Google Scholar
  • Swindle, M. M., Moody, D. C. and Phillips, L. D. (1992): Swine as Models in Biomedical Research. Iowa State University Press, Ames, Iowa. pp. 1–312.

    Phillips L. D. , '', in Swine as Models in Biomedical Research , (1992 ) -.

  • Szafranska, B., Ziecik, A. J. and Okrasa, S. (2002): Primary antisera against selected steroids or proteins and secondary antisera against γ-globulins — an available tool for studies of reproductive processes. Reprod. Biol. 5, 187–203.

    Okrasa S. , 'Primary antisera against selected steroids or proteins and secondary antisera against γ-globulins — an available tool for studies of reproductive processes ' (2002 ) 5 Reprod. Biol. : 187 -203.

    • Search Google Scholar
  • Tsang, P. C., Walton, J. S. and Hansel, W. (1990): Oxytocin-specific RNA, oxytocin and progesterone concentrations in corpora lutea of heifers treated with oxytocin. J. Reprod. Fertil. 89, 77–84.

    Hansel W. , 'Oxytocin-specific RNA, oxytocin and progesterone concentrations in corpora lutea of heifers treated with oxytocin ' (1990 ) 89 J. Reprod. Fertil. : 77 -84.

    • Search Google Scholar
  • Warnes, K. E., Morris, M. J., Symonds, M. E., Philips, I. D., Clarke, I. J., Owens, J. A. and McMillen, I. C. (1998): Effects of increasing gestation, cortisol and maternal undernutrition on hypothalamic neuropeptide Y expression in the sheep fetus. J. Neuroendocrinol. 10, 51–57.

    McMillen I. C. , 'Effects of increasing gestation, cortisol and maternal undernutrition on hypothalamic neuropeptide Y expression in the sheep fetus ' (1998 ) 10 J. Neuroendocrinol. : 51 -57.

    • Search Google Scholar

Author information is available in PDF.
Please, download the file from HERE.

The manuscript preparation instructions is available in PDF.
Please, download the file from HERE.

Senior editors

Editor-in-Chief: Mária BENKŐ

Managing Editor: András SZÉKELY

Editorial Board

  • Béla DÉNES (National Food Chain Safety Office, Budapest Hungary)
  • Edit ESZTERBAUER (Veterinary Medical Research Institute, Budapest, Hungary)
  • Hedvig FÉBEL (National Agricultural Innovation Centre, Herceghalom, Hungary)
  • László FODOR (University of Veterinary Medicine, Budapest, Hungary)
  • Balázs HARRACH (Veterinary Medical Research Institute, Budapest, Hungary)
  • Peter MASSÁNYI (Slovak University of Agriculture in Nitra, Nitra, Slovak Republic)
  • Béla NAGY (Veterinary Medical Research Institute, Budapest, Hungary)
  • Tibor NÉMETH (University of Veterinary Medicine, Budapest, Hungary)
  • Zsuzsanna NEOGRÁDY (University of Veterinary Medicine, Budapest, Hungary)
  • Alessandra PELAGALLI (University of Naples Federico II, Naples, Italy)
  • Kurt PFISTER (Ludwig-Maximilians-University of Munich, Munich, Germany)
  • László SOLTI (University of Veterinary Medicine, Budapest, Hungary)
  • József SZABÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Péter VAJDOVICH (University of Veterinary Medicine, Budapest, Hungary)
  • János VARGA (University of Veterinary Medicine, Budapest, Hungary)
  • Štefan VILČEK (University of Veterinary Medicine in Kosice, Kosice, Slovak Republic)
  • Károly VÖRÖS (University of Veterinary Medicine, Budapest, Hungary)
  • Herbert WEISSENBÖCK (University of Veterinary Medicine, Vienna, Austria)
  • Attila ZSARNOVSZKY (Szent István University, Gödöllő, Hungary)

ACTA VETERINARIA HUNGARICA
Institute for Veterinary Medical Research
Centre for Agricultural Research
Hungarian Academy of Sciences
P.O. Box 18, H-1581 Budapest, Hungary
Phone: (36 1) 467 4081 (ed.-in-chief) or (36 1) 213 9793 (editor) Fax: (36 1) 467 4076 (ed.-in-chief) or (36 1) 213 9793

Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • Chemical Abstracts
  • Current Contents: Agriculture, Biology and Environmental Sciences
  • Elsevier Science Navigator
  • Focus On: Veterinary Science and Medicine
  • Global Health
  • Index Medicus
  • Index Veterinarius
  • Medline
  • Science Citation Index
  • Science Citation Index Expanded (SciSearch)
  • SCOPUS
  • The ISI Alerting Services
  • Zoological Abstracts

 

2020  
Total Cites 987
WoS
Journal
Impact Factor
0,955
Rank by Veterinary Sciences 101/146 (Q3)
Impact Factor  
Impact Factor 0,920
without
Journal Self Cites
5 Year 1,164
Impact Factor
Journal  0,57
Citation Indicator  
Rank by Journal  Veterinary Sciences 93/166 (Q3)
Citation Indicator   
Citable 49
Items
Total 49
Articles
Total 0
Reviews
Scimago 33
H-index
Scimago 0,395
Journal Rank
Scimago Veterinary (miscellaneous) Q2
Quartile Score  
Scopus 355/217=1,6
Scite Score  
Scopus General Veterinary 73/183 (Q2)
Scite Score Rank  
Scopus 0,565
SNIP  
Days from  145
sumbission  
to acceptance  
Days from  150
acceptance  
to publication  
Acceptance 19%
Rate

 

2019  
Total Cites
WoS
798
Impact Factor 0,991
Impact Factor
without
Journal Self Cites
0,897
5 Year
Impact Factor
1,092
Immediacy
Index
0,119
Citable
Items
59
Total
Articles
59
Total
Reviews
0
Cited
Half-Life
9,1
Citing
Half-Life
9,2
Eigenfactor
Score
0,00080
Article Influence
Score
0,253
% Articles
in
Citable Items
100,00
Normalized
Eigenfactor
0,09791
Average
IF
Percentile
42,606
Scimago
H-index
32
Scimago
Journal Rank
0,372
Scopus
Scite Score
335/213=1,6
Scopus
Scite Score Rank
General Veterinary 62/178 (Q2)
Scopus
SNIP
0,634
Acceptance
Rate
18%

 

Acta Veterinaria Hungarica
Publication Model Hybrid
Submission Fee none
Article Processing Charge 1100 EUR/article
Printed Color Illustrations 40 EUR (or 10 000 HUF) + VAT / piece
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription fee 2021 Online subsscription: 696 EUR / 872 USD
Print + online subscription: 804 EUR / 1004 USD
Subscription fee 2022 Online subsscription: 710 EUR / 892 USD
Print + online subscription: 824 EUR / 1028 USD
Subscription Information Online subscribers are entitled access to all back issues published by Akadémiai Kiadó for each title for the duration of the subscription, as well as Online First content for the subscribed content.
Purchase per Title Individual articles are sold on the displayed price.

Acta Veterinaria Hungarica
Language English
Size A4
Year of
Foundation
1951
Publication
Programme
2020 Volume 68
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-6290 (Print)
ISSN 1588-2705 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Apr 2021 2 0 0
May 2021 1 0 0
Jun 2021 1 0 0
Jul 2021 9 0 0
Aug 2021 1 0 0
Sep 2021 4 0 0
Oct 2021 0 0 0