Authors:
Yu Mao Hunan Agricultural University, Changsha, Hunan 410128, P. R. China

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Jin Jun Li Hunan Agricultural University, Changsha, Hunan 410128, P. R. China

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Yuan Liu Hunan Agricultural University, Changsha, Hunan 410128, P. R. China

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Wei Dong Hunan Agricultural University, Changsha, Hunan 410128, P. R. China

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Pei Pang Hunan Agricultural University, Changsha, Hunan 410128, P. R. China

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Zhi Bang Deng Hunan Agricultural University, Changsha, Hunan 410128, P. R. China

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Porcine circovirus type 2- (PCV2-) associated reproductive disorders and enteritis have commonly been observed on PCV2-contaminated pig farms in recent years. In order to investigate disorders of intestinal immunity in piglets infected by PCV2 during the fetal period, 9 PCV2b-infected piglets and 6 non-infected piglets at one day of age were selected and euthanised prior to suckling. Samples of mesenteric lymph nodes (MLNs) and duodena were collected to investigate factors related to intestinal immunity and to detect lymphocytic apoptosis. The results indicated that there were no significant changes in the levels of IL-2, IL-10 and transforming growth factor-β (TGF-β) in the PCV2b-infected piglets but IFN-γ levels were significantly lower (P < 0.01) and IL-4 levels were significantly higher (P < 0.05) in infected piglets than in the controls. Furthermore, lymphocytic apoptosis increased in PCV2b-infected piglets and CD4+ to CD8+ ratios were lower in these piglets than in the controls. These findings suggest vertical transmission of PCV2b to fetuses, leading to an imbalance of intestinal immune function in piglets.

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  • Allan, G. M., McNeilly, F., Meehan, B. M., Kennedy, S., Mackie, D. P., Ellis, J. A., Clark, E. G., Espuna, E., Saubi, N., Riera, P., Botner, A. and Charreyre, C. E. (1999): Isolation and characterisation of circoviruses from pigs with wasting syndromes in Spain, Denmark and Northern Ireland. Vet. Microbiol. 66, 115123.

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  • Baró, J., Segalés, J. and Martínez, J. (2015): Porcine circovirus type 2 (PCV2) enteric disease: an independent condition or part of the systemic disease? Vet. Microbiol. 176, 8387.

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  • Bianco, C., Felice, V., Panarese, S., Marrocco, R., Ostanello, F., Brunetti, B., Muscatello, L. V., Leotti, G., Vila, T., Joisel, F. and Sarli, G. (2014): Quantitative immunohistochemical assessment of IgA, IgM, IgG and antigen-specific immunoglobulin secreting plasma cells in pig small intestinal lamina propria. Vet. Immunol. Immunopathol. 160, 281287.

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  • Cecere, T. E., Meng, X. J., Pelzer, K., Todd, S. M., Beach, N. M., Ni, Y. Y. and Leroith, T. (2012): Co-infection of porcine dendritic cells with porcine circovirus type 2a (PCV2a) and genotype II porcine reproductive and respiratory syndrome virus (PRRSV) induces CD4(+) CD25(+) FoxP3(+) T cells in vitro. Vet. Microbiol. 160, 233239.

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  • de Castro, A. M., Cruz, T. F., Salgado, V. R., Kanashiro, T. M., Ferrari, K. L., Brandão, P. E. and Richtzenhain, L. J. (2012): Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil. Acta Vet. Scand. 54, 29.

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  • Deng, Z. B., Yuan, A. W., Luo, W., Wang, N. D., Gong, Q. L., Yu, X. L. and Xue, L. Q. (2013): Transmission of porcine circovirus type 2b (PCV2b) in Kunming mice. Acta Vet. Hung. 61, 234243.

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  • Hansen, M. S., Hjulsager, C. K., Bille-Hansen, V., Hauqeqaard, S., Dupont, K., Hoqedal, P., Kunstmann, L. and Larsen, L. E. (2010): Selection of method is crucial for the diagnosis of porcine circovirus type 2 associated reproductive failures. Vet. Microbiol. 144, 203209.

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  • Kawashima, K., Tsunemitsu, H., Horino, R., Katsuda, K., Onodera, T., Shoji, T., Kubo, M., Haritani, M. and Murakami, Y. (2003): Effects of dexamethasone on the pathogenesis of porcine circovirus type 2 infection in piglets. J. Comp. Pathol. 129, 294302.

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  • Kekarainen, T., Montoya, M., Mateu, E. and Segalés, E. (2008): Porcine circovirus type 2 induced interleukin-10 modulates recall antigen responses. J. Gen. Virol. 89, 760765.

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  • Kim, J., Ha, Y., Jung, K., Choi, C. and Chae, C. (2004): Enteritis associated with porcine circovirus 2 in pigs. Can. J. Vet. Res. 68, 218221.

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  • Marco-Ramell, A., Miller, I., Nöbauer, K., Möginger, U., Segalés, J., Razzazi-Fazeli, E., Kolarich, D. and Bassols, A. (2014): Proteomics on porcine haptoglobin and IgG/IgA show protein species distribution and glycosylation pattern to remain similar in PCV2-SD infection. J. Proteomics 101, 205216.

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  • O’Connor, B., Gauvreau, H., West, K., Bogdan, J., Ayroud, M., Clark, E. G., Konoby, C., Allan, G. and Ellis, J. A. (2001): Multiple porcine circovirus 2-associated abortions and reproductive failure in a multisite swine production unit. Can. Vet. J. 42, 551553.

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  • Opriessnig, T., Madson, D. M., Roof, M., Layton, S. M., Ramamoorthy, S., Meng, X. J. and Halbur, P. G. (2011): Experimental reproduction of porcine circovirus type 2 (PCV2)-associated enteritis in pigs infected with PCV2 alone or concurrently with Lawsonia intracellularis or Salmonella typhimurium. J. Comp. Pathol. 145, 261270.

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  • Studdert, M. J. (1993): Circoviridae: new viruses of pigs, parrots and chickens. Aust. Vet. J. 70, 121122.

  • West, K. H., Bystrom, J. M., Wojnarowicz, C., Shantz, N., Jacobson, M., Allan, G. M., Haines, D. M., Clark, E. G., Krakowka, S., McNeilly, F., Konoby, C., Martin, K. and Ellis, J. A. (1990): Myocarditis and abortion associated with intrauterine infection of sows with porcine circovirus 2. J. Vet. Diagn. Invest. 11, 530532.

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Senior editors

Editor-in-Chief: Ferenc BASKA

 

Editorial Board

  • Béla DÉNES (National Food Chain Safety Office, Budapest Hungary)
  • Edit ESZTERBAUER (Veterinary Medical Research Institute, Budapest, Hungary)
  • Hedvig FÉBEL (National Agricultural Innovation Centre, Herceghalom, Hungary)
  • László FODOR (University of Veterinary Medicine, Budapest, Hungary)
  • Balázs HARRACH (Veterinary Medical Research Institute, Budapest, Hungary)
  • Peter MASSÁNYI (Slovak University of Agriculture in Nitra, Nitra, Slovak Republic)
  • Béla NAGY (Veterinary Medical Research Institute, Budapest, Hungary)
  • Tibor NÉMETH (University of Veterinary Medicine, Budapest, Hungary)
  • Zsuzsanna NEOGRÁDY (University of Veterinary Medicine, Budapest, Hungary)
  • Alessandra PELAGALLI (University of Naples Federico II, Naples, Italy)
  • Kurt PFISTER (Ludwig-Maximilians-University of Munich, Munich, Germany)
  • László SOLTI (University of Veterinary Medicine, Budapest, Hungary)
  • József SZABÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Péter VAJDOVICH (University of Veterinary Medicine, Budapest, Hungary)
  • János VARGA (University of Veterinary Medicine, Budapest, Hungary)
  • Štefan VILČEK (University of Veterinary Medicine in Kosice, Kosice, Slovak Republic)
  • Károly VÖRÖS (University of Veterinary Medicine, Budapest, Hungary)
  • Herbert WEISSENBÖCK (University of Veterinary Medicine, Vienna, Austria)
  • Attila ZSARNOVSZKY (Szent István University, Gödöllő, Hungary)

ACTA VETERINARIA HUNGARICA
Institute for Veterinary Medical Research
Centre for Agricultural Research
Hungarian Academy of Sciences
P.O. Box 18, H-1581 Budapest, Hungary
Phone: (36 1) 287 7073 (ed.-in-chief) or (36 1) 467 4081 (editor)

E-mail: actavet@vmri.hu (ed.-in-chief)

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2022  
Web of Science  
Total Cites
WoS
972
Journal Impact Factor 0.900
Rank by Impact Factor

Veterinary Sciences 95/143

Impact Factor
without
Journal Self Cites
0.900
5 Year
Impact Factor
1.1
Journal Citation Indicator 0.47
Rank by Journal Citation Indicator

Veterinary Sciences 103/170

Scimago  
Scimago
H-index
38
Scimago
Journal Rank
0.277
Scimago Quartile Score

Veterinary (miscellaneous) Q2

Scopus  
Scopus
Cite Score
1.9
Scopus
CIte Score Rank
General Veterinary 76/186 (59th PCTL)
Scopus
SNIP
0.475

2021  
Web of Science  
Total Cites
WoS
1040
Journal Impact Factor 0,959
Rank by Impact Factor Veterinary Sciences 103/144
Impact Factor
without
Journal Self Cites
0,876
5 Year
Impact Factor
1,222
Journal Citation Indicator 0,48
Rank by Journal Citation Indicator Veterinary Sciences 106/168
Scimago  
Scimago
H-index
36
Scimago
Journal Rank
0,313
Scimago Quartile Score Veterinary (miscellaneous) (Q2)
Scopus  
Scopus
Cite Score
1,7
Scopus
CIte Score Rank
General Veterinary 79/183 (Q2)
Scopus
SNIP
0,610

2020  
Total Cites 987
WoS
Journal
Impact Factor
0,955
Rank by Veterinary Sciences 101/146 (Q3)
Impact Factor  
Impact Factor 0,920
without
Journal Self Cites
5 Year 1,164
Impact Factor
Journal  0,57
Citation Indicator  
Rank by Journal  Veterinary Sciences 93/166 (Q3)
Citation Indicator   
Citable 49
Items
Total 49
Articles
Total 0
Reviews
Scimago 33
H-index
Scimago 0,395
Journal Rank
Scimago Veterinary (miscellaneous) Q2
Quartile Score  
Scopus 355/217=1,6
Scite Score  
Scopus General Veterinary 73/183 (Q2)
Scite Score Rank  
Scopus 0,565
SNIP  
Days from  145
submission  
to acceptance  
Days from  150
acceptance  
to publication  
Acceptance 19%
Rate

 

2019  
Total Cites
WoS
798
Impact Factor 0,991
Impact Factor
without
Journal Self Cites
0,897
5 Year
Impact Factor
1,092
Immediacy
Index
0,119
Citable
Items
59
Total
Articles
59
Total
Reviews
0
Cited
Half-Life
9,1
Citing
Half-Life
9,2
Eigenfactor
Score
0,00080
Article Influence
Score
0,253
% Articles
in
Citable Items
100,00
Normalized
Eigenfactor
0,09791
Average
IF
Percentile
42,606
Scimago
H-index
32
Scimago
Journal Rank
0,372
Scopus
Scite Score
335/213=1,6
Scopus
Scite Score Rank
General Veterinary 62/178 (Q2)
Scopus
SNIP
0,634
Acceptance
Rate
18%

 

Acta Veterinaria Hungarica
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Acta Veterinaria Hungarica
Language English
Size A4
Year of
Foundation
1951
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-6290 (Print)
ISSN 1588-2705 (Online)

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