View More View Less
  • 1 Shiraz University, P.O. Box 71441-69155, Shiraz, Iran
  • | 2 Shiraz University, P.O. Box 71441-69155, Shiraz, Iran
Restricted access

Purchase article

USD  $25.00

1 year subscription (Individual Only)

USD  $836.00

The study compares the effect of one-time administration of nonsteroidal and/or steroidal anti-inflammatory combinations by topical or intramuscular (IM) routes to pigeons with monosodium urate (MSU)-induced arthritis. Forty-five adult domestic pigeons were assigned into nine equal groups: NC, negative control; PC, positive control with arthritis; sham, sham control; T1, meloxicam + hydrocortisone; T2, dexamethasone + piroxicam; T3, meloxicam + dexamethasone; T4, hydrocortisone + piroxicam; T5, dexamethasone + hydrocortisone; T6, meloxicam + piroxicam. Arthritis was also induced in T1 to T6 birds. Meloxicam and dexamethasone were administered by IM injection and the other drugs topically right after the induction of arthritis. Different drug combinations significantly decreased one-leg standing time. Induction of arthritis significantly increased TNF-α and IL-6 levels in synovial fluid and serum corticosterone and epinephrine in the PC group. Administration of drugs to birds of Groups T1 and T5 did not significantly change corticosterone concentration, while all different drug combinations decreased epinephrine level. Drug combinations that demonstrated better analgesic effect more strongly reduced serum epinephrine concentration. Meloxicam + hydrocortisone was the most effective combination in reducing inflammatory cytokines. In conclusion, one-time combination therapy with anti-inflammatory agents was effective in the acute management of inflammatory pain due to MSU-induced arthritis in pigeons, even by the topical route.

  • Brune, K., Walz, D. and Bucher, K. E. (1974): The avian microcrystal arthritis I. Simultaneous recording of nociception and temperature effect in the inflamed joint. Agents Actions 4, 2126.

    • Search Google Scholar
    • Export Citation
  • Cavalcanti, N. G., Marques, C. D., Lins e Lins, T. U., Pereira, M. C., Rêgo, M. J., Duarte, A. L., Pitta, I. R. and Pitta, M. G. (2016): Cytokine profile in gout: inflammation driven by IL-6 and IL-18? Immunol. Invest. 45, 383395.

    • Search Google Scholar
    • Export Citation
  • Cockrem, J. F., Barrett, D. P., Candy, E. J. and Potter, M. A. (2009): Corticosterone responses in birds: individual variation and repeatability in Adelie penguins (Pygoscelis adeliae) and other species, and the use of power analysis to determine sample sizes. Gen. Comp. Endocrinol. 163, 158168.

    • Search Google Scholar
    • Export Citation
  • Cole, G. A., Paul-Murphy, J., Krugner-Higby, L., Klauer, J. M., Medlin, S. E., Keuler, N. S. and Sladky, K. K. (2009): Analgesic effects of IM administration of meloxicam in Hispaniolan parrots (Amazona ventralis) with experimentally induced arthritis. Am. J. Vet. Res. 70, 14711476.

    • Search Google Scholar
    • Export Citation
  • Dhanasekar, C. and Rasool, M. (2016): Morin, a dietary bioflavonol suppresses monosodium urate crystal-induced inflammation in an animal model of acute gouty arthritis with reference to NLRP3 inflammasome, hypo-xanthine phospho-ribosyl transferase, and inflammatory mediators. Eur. J. Pharmacol. 786, 116127.

    • Search Google Scholar
    • Export Citation
  • di Comite, G., Marinosci, A., Di Matteo, P., Manfredi, A., Rovere-Querini, P., Baldissera, E., Aiello, P., Corti, A. and Sabbadini, M. G. (2006): Neuroendocrine modulation induced by selective blockade of TNF-alpha in rheumatoid arthritis. Ann. N. Y. Acad. Sci. 1069, 428437.

    • Search Google Scholar
    • Export Citation
  • Faires, J. S. and McCarty, D. J. (1962): Acute arthritis in man and dog after intrasynovial injection of sodium urate crystals. The Lancet 280, 682685.

    • Search Google Scholar
    • Export Citation
  • Feldmann, M. (2002): Development of anti-TNF therapy for rheumatoid arthritis. Nat. Rev. Immunol. 2, 364371.

  • Floersheim, G. L., Brune, K. and Seiler, K. (1973): Colchicine in avian sodium urate and calcium pyrophosphate microcrystal arthritis. Agents Actions 3, 2023.

    • Search Google Scholar
    • Export Citation
  • Gentle, M. J., Hocking, P. M., Bernard, R. and Dunn, L. N. (1999): Evaluation of intraarticular opioid analgesia for the relief of articular pain in the domestic fowl. Pharmacol. Biochem. Behav. 63, 339343.

    • Search Google Scholar
    • Export Citation
  • Guerne, P. A., Terkeltaub, R., Zuraw, B. and Lotz, M. (1989): Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes. Arthritis Rheum. 32, 14431452.

    • Search Google Scholar
    • Export Citation
  • Hocking, P. M., Gentle, M. J., Bernard, R. and Dunn, L. N. (1997): Evaluation of a protocol for determining the effectiveness of pretreatment with local analgesics for reducing experimentally induced articular pain in domestic fowl. Res. Vet. Sci. 63, 263267.

    • Search Google Scholar
    • Export Citation
  • Hocking, P. M., Robertson, G. W. and Gentle, M. J. (2001): Effects of anti-inflammatory steroid drugs on pain coping behaviours in a model of articular pain in the domestic fowl. Res. Vet. Sci. 71, 161166.

    • Search Google Scholar
    • Export Citation
  • Hocking, P. M., Robertson, G. W. and Gentle, M. J. (2005): Effects of non-steroidal antiinflammatory drugs on pain-related behaviour in a model of articular pain in the domestic fowl. Res. Vet. Sci. 78, 6975.

    • Search Google Scholar
    • Export Citation
  • Kou, Y. Y., Li, Y. F., Xu, M., Li, W. Y., Yang, M. and Li, R. L. (2015): Effects of RuPeng15 Powder (RPP15) on monosodium urate crystal-induced gouty arthritis in rats. Evid. Based Complement. Alternat. Med. doi:10.1155/2015/527019

    • Search Google Scholar
    • Export Citation
  • Le Maho, Y., Karmann, H., Briot, D., Handrich, Y., Robin, J. P., Mioskowski, E., Cherel, Y. and Farni, J. (1992): Stress in birds due to routine handling and a technique to avoid it. Am. J. Physiol. 263, R775781.

    • Search Google Scholar
    • Export Citation
  • Leppert, W. and Buss, T. (2012): The role of corticosteroids in the treatment of pain in cancer patients. Curr. Pain Headache Rep. 16, 307313.

    • Search Google Scholar
    • Export Citation
  • Liu-Bryan, R., Scott, P., Sydlaske, A., Rose, D. M. and Terkeltaub, R. (2005): Innate immunity conferred by toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation. Arthritis Rheum. 52, 29362946.

    • Search Google Scholar
    • Export Citation
  • Machin, K. L. (2014): Recognition and treatment of pain in birds. In: Egger, C. M., Love, L. and Doherty, T. (eds) Pain Management in Veterinary Practice. First edition. John Wiley & Sons, Inc. pp. 407415.

    • Search Google Scholar
    • Export Citation
  • Malik, A. and Valentine, A. (2018): Pain in birds: a review for veterinary nurses. Vet. Nursing J. 33, 1125.

  • Mazor-Thomas, J. E., Mann, P. E., Karas, A. Z. and Tseng, F. (2014): Pain-suppressed behaviors in the red-tailed hawk (Buteo jamaicensis). Appl. Anim. Behav. Sci. 152, 8391.

    • Search Google Scholar
    • Export Citation
  • Paul-Murphy, J., Sladky, K. K., McCutcheon, R. A., Steege, E. and Converse, A. K. (2005): Using positron emission tomography imaging of the parrot brain to study response to clinical pain. Paper presented at the 2005 Annual Conference of the Academy of Molecular Imaging. Orlando (FL), March 18-23, 2005.

    • Search Google Scholar
    • Export Citation
  • Plumb, D. C. (2008): Plumb's Veterinary Drug Handbook, 6th edition. Blackwell Publishing, USA.

  • Riviere, J. E. and Papich, M. G. (2009): Veterinary Pharmacology and Therapeutics. 9th edition. Wiley-Blackwell, USA.

  • Rohde, F., Schusser, B., Hron, T., Farkašová, H., Plachy, J., Härtle, S., Hejnar, J., Elleder, D. and Kaspers, B. (2018): Characterization of chicken tumor necrosis factor-α, a long missed cytokine in birds. Front. Immunol. 9, 605. doi:10.3389/fimmu.2018.00605

    • Search Google Scholar
    • Export Citation
  • Sharara-Chami, R. I., Joachim, M., Pacak, K. and Majzoub, J. A. (2010): Glucocorticoid treatment – effect on adrenal medullary catecholamine production. Shock 33, 213217.

    • Search Google Scholar
    • Export Citation
  • Steer, J. H., Kroeger, K. M., Abraham, L. J. and Joyce, D. A. (2000): Glucocorticoids suppress tumor necrosis factor-alpha expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-kappa B and c-Jun-activating transcription factor-2 binding sites in the promoter. J. Biol. Chem. 275, 1843218440.

    • Search Google Scholar
    • Export Citation
  • Tennant, F. (2013): The physiologic effects of pain on the endocrine system. Pain Ther. 2, 7586.

Author information is available in PDF.
Please, download the file from HERE.

The manuscript preparation instructions is available in PDF.
Please, download the file from HERE.

Senior editors

Editor-in-Chief: Mária BENKŐ

Managing Editor: András SZÉKELY

Editorial Board

  • Béla DÉNES (National Food Chain Safety Office, Budapest Hungary)
  • Edit ESZTERBAUER (Veterinary Medical Research Institute, Budapest, Hungary)
  • Hedvig FÉBEL (National Agricultural Innovation Centre, Herceghalom, Hungary)
  • László FODOR (University of Veterinary Medicine, Budapest, Hungary)
  • Balázs HARRACH (Veterinary Medical Research Institute, Budapest, Hungary)
  • Peter MASSÁNYI (Slovak University of Agriculture in Nitra, Nitra, Slovak Republic)
  • Béla NAGY (Veterinary Medical Research Institute, Budapest, Hungary)
  • Tibor NÉMETH (University of Veterinary Medicine, Budapest, Hungary)
  • Zsuzsanna NEOGRÁDY (University of Veterinary Medicine, Budapest, Hungary)
  • Alessandra PELAGALLI (University of Naples Federico II, Naples, Italy)
  • Kurt PFISTER (Ludwig-Maximilians-University of Munich, Munich, Germany)
  • László SOLTI (University of Veterinary Medicine, Budapest, Hungary)
  • József SZABÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Péter VAJDOVICH (University of Veterinary Medicine, Budapest, Hungary)
  • János VARGA (University of Veterinary Medicine, Budapest, Hungary)
  • Štefan VILČEK (University of Veterinary Medicine in Kosice, Kosice, Slovak Republic)
  • Károly VÖRÖS (University of Veterinary Medicine, Budapest, Hungary)
  • Herbert WEISSENBÖCK (University of Veterinary Medicine, Vienna, Austria)
  • Attila ZSARNOVSZKY (Szent István University, Gödöllő, Hungary)

ACTA VETERINARIA HUNGARICA
Institute for Veterinary Medical Research
Centre for Agricultural Research
Hungarian Academy of Sciences
P.O. Box 18, H-1581 Budapest, Hungary
Phone: (36 1) 467 4081 (ed.-in-chief) or (36 1) 213 9793 (editor) Fax: (36 1) 467 4076 (ed.-in-chief) or (36 1) 213 9793

Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • Chemical Abstracts
  • Current Contents: Agriculture, Biology and Environmental Sciences
  • Elsevier Science Navigator
  • Focus On: Veterinary Science and Medicine
  • Global Health
  • Index Medicus
  • Index Veterinarius
  • Medline
  • Science Citation Index
  • Science Citation Index Expanded (SciSearch)
  • SCOPUS
  • The ISI Alerting Services
  • Zoological Abstracts

 

2020  
Total Cites 987
WoS
Journal
Impact Factor
0,955
Rank by Veterinary Sciences 101/146 (Q3)
Impact Factor  
Impact Factor 0,920
without
Journal Self Cites
5 Year 1,164
Impact Factor
Journal  0,57
Citation Indicator  
Rank by Journal  Veterinary Sciences 93/166 (Q3)
Citation Indicator   
Citable 49
Items
Total 49
Articles
Total 0
Reviews
Scimago 33
H-index
Scimago 0,395
Journal Rank
Scimago Veterinary (miscellaneous) Q2
Quartile Score  
Scopus 355/217=1,6
Scite Score  
Scopus General Veterinary 73/183 (Q2)
Scite Score Rank  
Scopus 0,565
SNIP  
Days from  145
sumbission  
to acceptance  
Days from  150
acceptance  
to publication  
Acceptance 19%
Rate

 

2019  
Total Cites
WoS
798
Impact Factor 0,991
Impact Factor
without
Journal Self Cites
0,897
5 Year
Impact Factor
1,092
Immediacy
Index
0,119
Citable
Items
59
Total
Articles
59
Total
Reviews
0
Cited
Half-Life
9,1
Citing
Half-Life
9,2
Eigenfactor
Score
0,00080
Article Influence
Score
0,253
% Articles
in
Citable Items
100,00
Normalized
Eigenfactor
0,09791
Average
IF
Percentile
42,606
Scimago
H-index
32
Scimago
Journal Rank
0,372
Scopus
Scite Score
335/213=1,6
Scopus
Scite Score Rank
General Veterinary 62/178 (Q2)
Scopus
SNIP
0,634
Acceptance
Rate
18%

 

Acta Veterinaria Hungarica
Publication Model Hybrid
Submission Fee none
Article Processing Charge 1100 EUR/article
Printed Color Illustrations 40 EUR (or 10 000 HUF) + VAT / piece
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription fee 2021 Online subsscription: 696 EUR / 872 USD
Print + online subscription: 804 EUR / 1004 USD
Subscription fee 2022 Online subsscription: 710 EUR / 892 USD
Print + online subscription: 824 EUR / 1028 USD
Subscription Information Online subscribers are entitled access to all back issues published by Akadémiai Kiadó for each title for the duration of the subscription, as well as Online First content for the subscribed content.
Purchase per Title Individual articles are sold on the displayed price.

Acta Veterinaria Hungarica
Language English
Size A4
Year of
Foundation
1951
Publication
Programme
2020 Volume 68
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-6290 (Print)
ISSN 1588-2705 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Apr 2021 54 0 0
May 2021 8 0 0
Jun 2021 10 0 0
Jul 2021 10 0 0
Aug 2021 11 0 0
Sep 2021 5 0 0
Oct 2021 0 0 0