Authors:
,
,
, and
Anja Strobl
Anja Strobl
Department for Companion Animals, Small Animal Clinic, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210, Vienna , Austria
Search for other papers by Anja Strobl in
Current site
Google Scholar
PubMed
Search for other papers by Anja Strobl in
Current site
Google Scholar
PubMed
Frank Künzel
Frank Künzel
Department for Companion Animals, Small Animal Clinic, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210, Vienna , Austria
Search for other papers by Frank Künzel in
Current site
Google Scholar
PubMed
Search for other papers by Frank Künzel in
Current site
Google Scholar
PubMed
Alexander Tichy
Alexander Tichy
Department of Biomedical Sciences, University of Veterinary Medicine Vienna, Vienna , Austria
Search for other papers by Alexander Tichy in
Current site
Google Scholar
PubMed
Search for other papers by Alexander Tichy in
Current site
Google Scholar
PubMed
Michael Leschnik
michael.leschnik@vetmeduni.ac.at
https://orcid.org/0000-0001-6312-8579
Michael Leschnik
Department for Companion Animals, Small Animal Clinic, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210, Vienna , Austria
Search for other papers by Michael Leschnik in
Current site
Google Scholar
PubMed
Search for other papers by Michael Leschnik in
Current site
Google Scholar
PubMed
Abstract
The purpose of this study was to investigate retrospectively the prevalence of the complicated and uncomplicated forms of babesiosis and to evaluate various laboratory and clinical parameters of dogs infected with Babesia canis in order to assess their prognostic value regarding the outcomes of the disease. Medical records, complete blood count and serum biochemical analysis from the animal hospital information system of 240 dogs were reviewed and evaluated retrospectively. Binary logistic regression analysis was used to ascertain correlations between alterations in the obtained parameters and survival probability. The results showed that creatinine levels of more than 5 mg/dL and phosphate levels of more than 3 mmol/L have a highly significant link to death (P ≤ 0.001). Albumin levels of <2.2 g/dL (P = 0.003) and a rectal body temperature below 38 °C (P ≤ 0.001) may also serve as prognostic markers for the severity of the disease. If renal involvement was present, 33.9% of the dogs died, while 40.0% of the dogs died in the presence of pancreatitis. The parameters creatinine, phosphate, albumin and rectal temperature serve as reliable predictive markers of an increased risk of death in the case of an infection with B. canis.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
Cacció, S. M., Antunovic, B., Moretti, A., Mangili, V., Marinculic, A., Rafaj Baric, R., Slemenda, S. B. and Pieniazek, N. J. (2002): Molecular characterisation of Babesia canis canis and Babesia canis vogeli from naturally infected European dogs. Vet. Parasitol. 106, 285–292.
-
Carcy, B., Randazzo, S., Depoix, D., Adaszek, L., Cardoso, L. and Baneth, G. (2015): Classification of Babesia canis strains in Europe based on polymorphism of the Bc28.1-gene from the Babesia canis Bc28 multigene family. Vet. Parasitol. 211, 111–123.
-
Duscher, G., Feiler, A., Leschnik, M. and Joachim, A. (2013): Seasonal and spatial distribution of ixodid tick species feeding on naturally infested dogs from Eastern Austria and the influence of acaricides/repellents on these parameters. Parasit. Vectors 6, 76.
-
Eckersall, P. D. and Bell, R. (2010): Acute phase proteins: biomarkers of infection and inflammation in veterinary medicine. Vet. J. 185, 23–27.
-
Eichenberger, R. M., Riond, B., Willi, B., Hofmann-Lehmann, R. and Deplazes, P. (2016): Prognostic markers in acute Babesia canis infections. J. Vet. Intern. Med. 30, 174–182.
-
Furlanello, T., Fiorio, F., Caldin, M., Lubas, G. and Solano-Gallego, L. (2005): Clinicopathological findings in naturally occurring cases of babesiosis caused by large form Babesia from dogs of northeastern Italy. Vet. Parasitol. 134, 77–85.
-
Goddard, A., Wiinberg, B., Schoeman, J. P., Kristensen, A. T. and Kjelgaard-Hansen, M. (2013): Mortality in virulent canine babesiosis is associated with a consumptive coagulopathy. Vet. J. 196, 213–217.
-
Hornok, S., Edelhofer, R. and Farkas, R. (2006): Seroprevalence of canine babesiosis in Hungary suggesting breed predisposition. Parasitol. Res. 99, 638–642.
-
Irwin, P. J. (2009): Canine babesiosis: from molecular taxonomy to control. Parasit. Vectors 2 (Suppl. 1 ),S4.
-
Jacobson, L. S. (2006): The South African form of severe and complicated canine babesiosis: clinical advances 1994–2004. Vet. Parasitol. 138, 126–139.
-
Kirtz, G., Leschnik, M., Hooijberg, E. H., Tichy, A. and Leidinger, E. (2012): In-clinic laboratory diagnosis of canine babesiosis (Babesia canis canis) for veterinary practitioners in Central Europe. Tierärztl. Prax. 40, 87–94.
-
Kuleš, J., Bilić, P., Beer Ljubić, B., Gotić, J., Crnogaj, M., Brkljačić, M. and Mrljak, V. (2018): Glomerular and tubular kidney damage markers in canine babesiosis caused by Babesia canis. Ticks Tick Borne Dis. 9, 1508–1517.
-
Leschnik, M. W., Khanakah, G., Duscher, G., Wille-Piazzai, W., Hörweg, C., Joachim, A. and Stanek, G. (2012): Species, developmental stage and infection with microbial pathogens of engorged ticks removed from dogs and questing ticks. Med. Vet. Entomol. 26, 440–446.
-
Martinod, S., Laurent, N. and Moreau, Y. (1986): Resistance and immunity of dogs against Babesia canis in an endemic area. Vet. Parasitol. 19, 245–254.
-
Máthé, A., Vörös, K., Papp, L. and Reiczigel, J. (2006): Clinical manifestations of canine babesiosis in Hungary (63 cases). Acta Vet. Hung. 54, 367–385.
-
Matijatko, V., Kis, I., Torti, M., Brkljacić, M., Kucer, N. and Baric Rafaj, R. (2009): Septic shock in canine babesiosis. Vet. Parasitol. 162, 263–270.
-
Matijatko, V., Torti, M., Kiš, I., Šmit, I., Štoković, I., Vranješ-Đurić, T., Milanović, S., Mrljak, V. and Brkljačić, M. (2014): Serum cortisol and insulin concentrations in dogs naturally infected with Babesia canis. Vet. Arh. 84, 551–562.
-
Nel, M., Lobetti, R. G., Keller, N. and Thompson, P. N. (2004): Prognostic value of blood lactate, blood glucose, and hematocrit in canine babesiosis. J. Vet. Int. Med. 18, 471–476.
-
Schetters, T. (2019): Mechanisms involved in the persistence of Babesia canis infection in dogs. Pathogens 8, 94.
-
Schetters, T. P., Kleuskens, J. A., Van De Crommert, J., De Leeuw, P. W., Finizio, A. L. and Gorenflot, A. (2009): Systemic inflammatory responses in dogs experimentally infected with Babesia canis; a haematological study. Vet. Parasitol. 162, 7–15.
-
Solano-Gallego, L. and Baneth, G. (2011): Babesiosis in dogs and cats – expanding parasitological and clinical spectra. Vet. Parasitol. 181, 48–60.
-
Solano-Gallego, L., Sainz, Á., Roura, X., Estrada-Peña, A. and Miró, G. (2016): A review of canine babesiosis: the European perspective. Parasit. Vectors 9, 336.
-
Stockham, S. L. and Scott, M. A. (2008): Calcium, phosphorus, magnesium, and their regulatory hormones. In: Stockham, S. L. and Scott, M. A. (eds) Fundamentals of Veterinary Clinical Pathology. 2nd edition. Wiley-Blackwell, Oxford. pp. 539–638.
-
Wong, D. M. and Wilkins, P. A. (2015): Defining the systemic inflammatory response syndrome in equine neonates. Vet. Clin. North Am. Equine Pract. 31, 463–481.
-
Zygner, W., Gójska-Zygner, O. and Wędrychowicz, H. (2012): Strong monovalent electrolyte imbalances in serum of dogs infected with Babesia canis. Ticks Tick Borne Dis. 3, 107–113.
ACTA VETERINARIA HUNGARICA
University of Veterinary Medicine,
H-1078 Budapest, István utca 2., Hungary
Phone: (36 20) 560 4183 (ed.-in-chief) or (36 1) 478 4100/8430 (editor)
E-mail: acta.veterinaria@univet.hu (ed.-in-chief)
Indexing and Abstracting Services:
- Biological Abstracts
- BIOSIS Previews
- CAB Abstracts
- Chemical Abstracts
- Current Contents: Agriculture, Biology and Environmental Sciences
- Elsevier Science Navigator
- Focus On: Veterinary Science and Medicine
- Global Health
- Index Medicus
- Index Veterinarius
- Medline
- Science Citation Index
- Science Citation Index Expanded (SciSearch)
- SCOPUS
- The ISI Alerting Services
- Zoological Abstracts
| 2023 | |
|---|---|
| Web of Science | |
| Journal Impact Factor | 0.7 |
| Rank by Impact Factor | Q3 (Veterinary Sciences) |
| Journal Citation Indicator | 0.4 |
| Scopus | |
| CiteScore | 1.8 |
| CiteScore rank | Q2 (General Veterinary) |
| SNIP | 0.39 |
| Scimago | |
| SJR index | 0.258 |
| SJR Q rank | Q3 |
| Acta Veterinaria Hungarica | |
|---|---|
| Publication Model | Hybrid |
| Submission Fee | none |
| Article Processing Charge | 1100 EUR/article |
| Printed Color Illustrations | 40 EUR (or 10 000 HUF) + VAT / piece |
| Regional discounts on country of the funding agency | World Bank Lower-middle-income economies: 50% World Bank Low-income economies: 100% |
| Further Discounts | Editorial Board / Advisory Board members: 50% Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100% |
| Subscription fee 2025 | Online subsscription: 832 EUR / 916 USD Print + online subscription: 960 EUR / 1054 USD |
| Subscription Information | Online subscribers are entitled access to all back issues published by Akadémiai Kiadó for each title for the duration of the subscription, as well as Online First content for the subscribed content. |
| Purchase per Title | Individual articles are sold on the displayed price. |
| Acta Veterinaria Hungarica | |
|---|---|
| Language | English |
| Size | A4 |
| Year of Foundation |
1951 |
| Volumes per Year |
1 |
| Issues per Year |
4 |
| Founder | Magyar Tudományos Akadémia |
| Founder's Address |
H-1051 Budapest, Hungary, Széchenyi István tér 9. |
| Publisher | Akadémiai Kiadó |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 0236-6290 (Print) |
| ISSN | 1588-2705 (Online) |
Monthly Content Usage
| Abstract Views | Full Text Views | PDF Downloads | |
|---|---|---|---|
| Jun 2024 | 69 | 0 | 0 |
| Jul 2024 | 51 | 0 | 0 |
| Aug 2024 | 60 | 0 | 0 |
| Sep 2024 | 61 | 0 | 0 |
| Oct 2024 | 157 | 3 | 4 |
| Nov 2024 | 60 | 0 | 0 |
| Dec 2024 | 14 | 1 | 1 |
Authors:
, , , , , , , and
Author:
Copyright Akadémiai Kiadó AKJournals is the trademark of Akadémiai Kiadó's journal publishing business branch.
Powered by PubFactory