Authors:
Federica Giorda Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D’Aosta, via Bologna 148, 10154, Torino, Italy
Institute of Animal Health, University of Las Palmas de Gran Canaria, Arucas, Las Palmas, Spain

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Giovanni Di Guardo Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy

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Katia Varello Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D’Aosta, via Bologna 148, 10154, Torino, Italy

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Alessandra Pautasso Department of Prevention, Local Veterinary Services (ASL1 Imperiese), Bussana di Sanremo, Imperia, Italy

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Eva Sierra Institute of Animal Health, University of Las Palmas de Gran Canaria, Arucas, Las Palmas, Spain

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Maria Domenica Pintore Department of Prevention, Local Veterinary Services (ASL VCO), Domodossola (VB), Italy

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Carla Grattarola Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D’Aosta, via Bologna 148, 10154, Torino, Italy

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Erika Molica Colella Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna, Brescia, Italy

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Enrica Berio Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D’Aosta, via Bologna 148, 10154, Torino, Italy

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Maria Goria Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D’Aosta, via Bologna 148, 10154, Torino, Italy

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Elena Bozzetta Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D’Aosta, via Bologna 148, 10154, Torino, Italy

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Cristina Casalone Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D’Aosta, via Bologna 148, 10154, Torino, Italy

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Barbara Iulini Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D’Aosta, via Bologna 148, 10154, Torino, Italy

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https://orcid.org/0000-0002-6037-5184
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Abstract

Dolphin morbillivirus (DMV) is a pathogen of great concern in free-ranging cetaceans. Confirmation and staging of morbillivirus infections rely on histology and immunohistochemistry (IHC), following molecular detection. As at the present time no specific antibodies (Abs) against DMV are available, two heterologous Abs have been used worldwide for the examinations of morbillivirus infections of cetaceans. One is a monoclonal Ab (MoAb) prepared against the N protein of canine distemper virus (CDV), whereas the other is a polyclonal Ab raised in rabbits against rinderpest virus (RPV). Both Abs are known to show cross-reactivity with DMV. In this study we compared the labelling quality and the neuroanatomical distribution of staining with these two Abs by means of IHC analysis. To this end, serial sections of the target organs from ten free-ranging stranded cetaceans, previously diagnosed as being infected with DMV by PCR and/or serology, were subjected to IHC. The brain, lungs and lymph nodes of one animal were found to be positive with both Abs. From two other animals, the brain and the spleen, respectively, tested positive only with the polyclonal Ab. In the positive brain tissues, multifocal immunostaining was observed, with similar staining location and extent, with the two antibodies tested. Our results suggest that the polyclonal anti-RPV Ab might have a stronger binding activity to DMV than the anti-CDV MoAb. Nevertheless, the elaboration and use of specific anti-DMV Abs might be essential to guarantee conclusive results in diagnostic and pathogenetic investigations.

  • Amude, A. M., Alfieri, A. F. and Alfieri, A. A. (2010): Use of immunohistochemistry and molecular assays such as RT-PCR for precise post mortem diagnosis of distemper-related encephalitis. In: Méndez-Vilas, A. (ed.) Current Research, Technology and Education Topics in Applied Microbiology and Microbial Biotechnology, Formatex, Spain. pp. 15391545.

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  • Di Guardo, G., Proietto, U., Di Francesco, C. E., Marsilio, F., Zaccaroni, A., Scaravelli, D., Mignone, W., Garibaldi, F., Kennedy, S., Forster, F., Iulini, B., Bozzetta, E. and Casalone, C. (2010): Cerebral toxoplasmosis in striped dolphins (Stenella coeruleoalba) stranded along the Ligurian Sea coast of Italy. Vet. Pathol. 47, 245253.

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  • Díaz-Delgado, J., Groch, K. R., Sierra, E., Sacchini, S., Zucca, D., Quesada-Canales, Ó., Arbelo, M., Fernández, A., Santos, E., Ikeda, J., Carvalho, R., Azevedo, A. F., Lailson-Brito, J. Jr., Flach, L., Ressio, R., Kanamura, C. T., Sansone, M., Favero, C., Porter, B. F., Centelleghe, C., Mazzariol, S., Di Renzo, L., Di Francesco, G., Di Guardo, G. and Catão- Dias, J. L. (2019): Comparative histopathologic and viral immunohistochemical studies on CeMV infection among Western Mediterranean, Northeast-Central, and Southwestern Atlantic cetaceans. PloS One 14, 121.

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  • Díaz-Delgado, J., Sierra, E., Vela, A. I., Arbelo, M., Zucca, D., Groch, K. R. and Fernández, A. (2017): Coinfection by Streptococcus phocae and cetacean morbillivirus in a short-beaked common dolphin Delphinus delphis. Dis. Aquat. Org. 124, 247252.

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  • Geraci, J. R. and Lounsbury, V. J. (2005): Marine Mammals Ashore: A Field Guide for Strandings. 2nd ed. National Aquarium in Baltimore, Baltimore, MD. 382 pp.

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  • Giorda, F., Ballardini, M., Di Guardo, G., Pintore, M. D., Grattarola, C., Iulini, B., Mignone, W., Goria, M., Serracca, L., Varello, K., Dondo, A., Acutis, P. L., Garibaldi, F., Scaglione, F. E., Gustinelli, A., Mazzariol, S., Di Francesco, C. E., Tittarelli, C., Casalone, C. and Pautasso, A. (2017): Postmortem findings in cetaceans found stranded in the Pelagos sanctuary, Italy, 2007–14. J. Wildl. Dis. 53, 795803.

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  • Pautasso, A., Iulini, B., Grattarola, C., Giorda, F., Goria, M., Peletto, S., Masoero, L., Mignone, W., Varello, K., Petrella, A., Carbone, A., Pintore, A., Denurra, D., Scholl, F., Cersini, A., Puleio, R., Purpari, G., Lucifora, G., Fusco, G., Di Guardo, G., Mazzariol, S. and Casalone C. (2019): Novel dolphin morbillivirus (DMV) outbreak among Mediterranean striped dolphins Stenella coeruleoalba in Italian waters. Dis. Aquat. Org. 132, 215220.

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  • Peletto, S., Caruso, C., Cerutti, F., Modesto, P., Biolatti, C. Pautasso, A., Grattarola, C., Giorda, F., Mazzariol, S., Mignone, W., Masoero, L., Casalone, C. and Acutis, P. L. (2018): Efficient isolation on Vero.DogSLAMtag cells and full genome characterization of Dolphin Morbillivirus (DMV) by next generation sequencing. Sci. Rep. 8, 18.

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  • Sergeant, E. S. G. (2018): Epitools Epidemiological Calculators, Ausvet Pty Ltd. Available from: http://epitools.ausvet.com.au.

  • Smedley, R. C., Patterson, J. S., Miller, R., Massey, J. P., Wise, A. G., Maes, R. K., Wu, P., Kaneene, J. B. and Kiupel, M. (2007): Sensitivity and specificity of monoclonal and polyclonal immunohistochemical staining for West Nile virus in various organs from American crows (Corvus brachyrhynchos). BMC Infect. Dis. 7, 19.

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  • Stanton, J. B., Brown, C. C., Poet, S., Lipscomb, T. P., Saliki, J. and Frasca, S., Jr. (2004): Retrospective differentiation of canine distemper virus and phocine distemper virus in phocids. J. Wildl. Dis. 40, 5359.

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  • Van Bressem, M. F., Duignan, P. J., Banyard, A., Barbieri, M., Colegrove, K. M., De Guise, S., Di Guardo, G., Dobson, A., Domingo, M., Fauquier, D., Fernandez, A., Goldstein, T., Grenfell, B., Groch, K. R., Gulland, F., Jensen, B. A., Jepson, P. D., Hall, A., Kuiken, T., Mazzariol, S., Morris, S. E., Nielsen, O., Raga, J. A., Rowles, T. K., Saliki, J., Sierra, E., Stephens, N., Stone, B., Tomo, I., Wang, J., Waltzek, T. and Wellehan, J. F. (2014): Cetacean morbillivirus: current knowledge and future directions. Viruses 6, 51455181.

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  • Verna, F., Giorda, F., Miceli, I., Rizzo, G., Pautasso, A., Romano, A., Iulini, B., Pintore, M. D., Mignone, W., Grattarola, C., Bozzetta, E., Varello, K., Dondo, A., Casalone, C. and Goria, M. (2017): Detection of morbillivirus infection by RT-PCR RFLP analysis in cetaceans and carnivores. J. Virol. Methods 247, 2227.

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  • Yang, W. C., Pang, V. F., Jeng, C. R., Chou, L. S. and Chueh, L. L. (2006): Morbilliviral infection in a pygmy sperm whale (Kogia breviceps) from Taiwanese waters. Vet. Microbiol. 116, 6976.

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Senior editors

Editor-in-Chief: Ferenc BASKA

 

Editorial Board

  • Béla DÉNES (National Food Chain Safety Office, Budapest Hungary)
  • Edit ESZTERBAUER (Veterinary Medical Research Institute, Budapest, Hungary)
  • Hedvig FÉBEL (National Agricultural Innovation Centre, Herceghalom, Hungary)
  • László FODOR (University of Veterinary Medicine, Budapest, Hungary)
  • Balázs HARRACH (Veterinary Medical Research Institute, Budapest, Hungary)
  • Peter MASSÁNYI (Slovak University of Agriculture in Nitra, Nitra, Slovak Republic)
  • Béla NAGY (Veterinary Medical Research Institute, Budapest, Hungary)
  • Tibor NÉMETH (University of Veterinary Medicine, Budapest, Hungary)
  • Zsuzsanna NEOGRÁDY (University of Veterinary Medicine, Budapest, Hungary)
  • Alessandra PELAGALLI (University of Naples Federico II, Naples, Italy)
  • Kurt PFISTER (Ludwig-Maximilians-University of Munich, Munich, Germany)
  • László SOLTI (University of Veterinary Medicine, Budapest, Hungary)
  • József SZABÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Péter VAJDOVICH (University of Veterinary Medicine, Budapest, Hungary)
  • János VARGA (University of Veterinary Medicine, Budapest, Hungary)
  • Štefan VILČEK (University of Veterinary Medicine in Kosice, Kosice, Slovak Republic)
  • Károly VÖRÖS (University of Veterinary Medicine, Budapest, Hungary)
  • Herbert WEISSENBÖCK (University of Veterinary Medicine, Vienna, Austria)
  • Attila ZSARNOVSZKY (Szent István University, Gödöllő, Hungary)

ACTA VETERINARIA HUNGARICA
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Centre for Agricultural Research
Hungarian Academy of Sciences
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2022  
Web of Science  
Total Cites
WoS
972
Journal Impact Factor 0.900
Rank by Impact Factor

Veterinary Sciences 95/143

Impact Factor
without
Journal Self Cites
0.900
5 Year
Impact Factor
1.1
Journal Citation Indicator 0.47
Rank by Journal Citation Indicator

Veterinary Sciences 103/170

Scimago  
Scimago
H-index
38
Scimago
Journal Rank
0.277
Scimago Quartile Score

Veterinary (miscellaneous) Q2

Scopus  
Scopus
Cite Score
1.9
Scopus
CIte Score Rank
General Veterinary 76/186 (59th PCTL)
Scopus
SNIP
0.475

2021  
Web of Science  
Total Cites
WoS
1040
Journal Impact Factor 0,959
Rank by Impact Factor Veterinary Sciences 103/144
Impact Factor
without
Journal Self Cites
0,876
5 Year
Impact Factor
1,222
Journal Citation Indicator 0,48
Rank by Journal Citation Indicator Veterinary Sciences 106/168
Scimago  
Scimago
H-index
36
Scimago
Journal Rank
0,313
Scimago Quartile Score Veterinary (miscellaneous) (Q2)
Scopus  
Scopus
Cite Score
1,7
Scopus
CIte Score Rank
General Veterinary 79/183 (Q2)
Scopus
SNIP
0,610

2020  
Total Cites 987
WoS
Journal
Impact Factor
0,955
Rank by Veterinary Sciences 101/146 (Q3)
Impact Factor  
Impact Factor 0,920
without
Journal Self Cites
5 Year 1,164
Impact Factor
Journal  0,57
Citation Indicator  
Rank by Journal  Veterinary Sciences 93/166 (Q3)
Citation Indicator   
Citable 49
Items
Total 49
Articles
Total 0
Reviews
Scimago 33
H-index
Scimago 0,395
Journal Rank
Scimago Veterinary (miscellaneous) Q2
Quartile Score  
Scopus 355/217=1,6
Scite Score  
Scopus General Veterinary 73/183 (Q2)
Scite Score Rank  
Scopus 0,565
SNIP  
Days from  145
submission  
to acceptance  
Days from  150
acceptance  
to publication  
Acceptance 19%
Rate

 

2019  
Total Cites
WoS
798
Impact Factor 0,991
Impact Factor
without
Journal Self Cites
0,897
5 Year
Impact Factor
1,092
Immediacy
Index
0,119
Citable
Items
59
Total
Articles
59
Total
Reviews
0
Cited
Half-Life
9,1
Citing
Half-Life
9,2
Eigenfactor
Score
0,00080
Article Influence
Score
0,253
% Articles
in
Citable Items
100,00
Normalized
Eigenfactor
0,09791
Average
IF
Percentile
42,606
Scimago
H-index
32
Scimago
Journal Rank
0,372
Scopus
Scite Score
335/213=1,6
Scopus
Scite Score Rank
General Veterinary 62/178 (Q2)
Scopus
SNIP
0,634
Acceptance
Rate
18%

 

Acta Veterinaria Hungarica
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Acta Veterinaria Hungarica
Language English
Size A4
Year of
Foundation
1951
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
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Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-6290 (Print)
ISSN 1588-2705 (Online)

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