View More View Less
  • 1 Clinical Unit of Internal Medicine Small Animals, University of Veterinary Medicine Vienna, , Veterinärplatz 1, 1210Vienna, , Austria
  • | 2 IDEXX Laboratories, Kornwestheim, , Germany
  • | 3 Clinical Pathology Platform, Veterinary University Vienna, Vienna, , Austria
  • | 4 Institute of Parasitology, Department of Pathobiology, Veterinary University Vienna, Vienna, , Austria
Restricted access

Purchase article

USD  $25.00

1 year subscription (Individual Only)

USD  $836.00

Abstract

A four-year-old intact male Boxer, that had a history of travelling to Serbia, was referred for lethargy and anaemia. Shortly before the dog was referred, it was diagnosed twice with an infection with Babesia canis and was treated with imidocarb both times. A blood smear evaluation was indicative of the presence of intraerythrocytic piroplasms. After receiving inconclusive results regarding the type of piroplasm, the dog was diagnosed with simultaneous infections with B. canis and Babesia gibsoni via real-time polymerase chain reaction (rt-PCR) testing. The dog was treated with imidocarb, atovaquone and azithromycin, and in a follow-up examination, the PCR results were negative for B. canis and B. gibsoni. Several weeks later, the dog was presented again, and a PCR was positive for B. gibsoni. After atovaquone and azithromycin failed to eliminate the parasites, a therapy attempt using metronidazole, clindamycin and doxycycline was initiated. Six months after diagnosis, the treatment appeared successful in eliminating B. gibsoni. This case report describes the clinical findings of the co-infection and the initiated diagnostic and therapeutic approaches.

  • Almendros, A. , Burchell, R. and Wierenga, J. (2020): An alternative combination therapy with metronidazole, clindamycin and doxycycline for Babesia gibsoni (Asian genotype) in dogs in Hong Kong. J. Vet. Med. Sci. 82, 13341340.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Baneth, G. (2018): Antiprotozoal treatment of canine babesiosis. Vet. Parasitol. 254, 5863.

  • Barić Rafaj, R. , Kuleš, J. , Selanec, J. , Vrkić, N. , Zovko, V. , Zupančič, M. , Trampuš Bakija, A. , Matijatko, V. , Crnogaj, M. and Mrljak, V. (2013): Markers of coagulation activation, endothelial stimulation, and inflammation in dogs with babesiosis. J. Vet. Intern. Med. 27, 11721178.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Birkenheuer, A. , Marr, H. , Wilson, J. , Breitschwerdt, E. and Qurollo, B. (2018): Babesia gibsoni cytochrome b mutations in canine blood samples submitted to a US veterinary diagnostic laboratory. J. Vet. Intern. Med. 32, 19651969.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Carcy, B. , Randazzo, S. , Depoix, D. , Adaszek, L. , Cardoso, L. , Baneth, G. , Gorenflot, A. and Schetters, T. (2015): Classification of Babesia canis strains in Europe based on polymorphism of the Bc28.1-gene from the Babesia canis Bc28 multigene family. Vet. Parasitol. 211, 111123.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Checa, R. , Fidalgo, L. E. , Montoya, A. , López, A. M. , Barrera, J. P. , Gálvez, R. , Sánchez de la Nieta, S. , Marino, V. , Sarquis, J. and Miró, G. (2019): The role of healthy dog carriers of Babesia microti-like piroplasms. Parasit. Vectors 12, 127.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Checa, R. , Montoya, A. , Ortega, N. , González-Fraga, J. L. , Bartolomé, A. , Gálvez, R. , Marino, V. and Miró, G. (2017): Efficacy, safety and tolerance of imidocarb dipropionate versus atovaquone or buparvaquone plus azithromycin used to treat sick dogs naturally infected with the Babesia microti-like piroplasm. Parasit. Vectors 10, 145.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Davitkov, D. , Vucicevic, M. , Stevanovic, J. , Krstic, V. , Tomanovic, S. , Glavinic, U. and Stanimirovic, Z. (2015): Clinical babesiosis and molecular identification of Babesia canis and Babesia gibsoni infections in dogs from Serbia. Acta Vet. Hung. 63, 199208.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Demeter, Z. , Palade, E. A. , Balogh, É. , Jakab, Cs. , Farkas, R. , Tánczos, B. and Hornok, S. (2011): Postmortem small babesia-like morphology of Babesia canis – Short communication. Acta Vet. Hung. 59, 427432.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Duscher, G. G. , Fuehrer, H. P. and Kübber-Heiss, A. (2014): Fox on the run – molecular surveillance of fox blood and tissue for the occurrence of tick-borne pathogens in Austria. Parasit. Vectors 7, 521.

    • Search Google Scholar
    • Export Citation
  • Dyachenko, V. , Pantchev, N. , Balzer, H. J. , Meyersen, A. and Straubinger, R. K. (2012): First case of Anaplasma platys infection in a dog from Croatia. Parasit. Vectors 5, 49.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Farkas, R. , Takács, N. , Hornyák, Á. , Nachum-Biala, Y. , Hornok, S. and Baneth, G. (2015): First report on Babesia cf. microti infection of red foxes (Vulpes vulpes) from Hungary. Parasit. Vectors 8, 55.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Furlanello, T. , Fiorio, F. , Caldin, M. , Lubas, G. and Solano-Gallego, L. (2005): Clinicopathological findings in naturally occurring cases of babesiosis caused by large form Babesia from dogs of northeastern Italy. Vet. Parasitol. 134, 7785.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Gabrielli, S. , Otašević, S. , Ignjatović, A. , Savić, S. , Fraulo, M. , Arsić-Arsenijević, V. , Momčilović, S. and Cancrini, G. (2015): Canine babesioses in noninvestigated areas of Serbia. Vector Borne Zoonotic Dis. 15, 535538.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Globokar Vrhovec, M. , Pantchev, N. , Failing, K. , Bauer, C. , Travers-Martin, N. and Zahner, H. (2017): Retrospective analysis of canine vector-borne diseases (CVBD) in Germany with emphasis on the endemicity and risk factors of leishmaniosis. Parasitol. Res. 116 (Suppl. 1 ),131144.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Hodžić, A. , Mrowietz, N. , Cézanne, R. , Bruckschwaiger, P. , Punz, S. , Habler, V. E. , Tomsik, V. , Lazar, J. , Duscher, G. G. , Glawischnig, W. and Fuehrer, H. P. (2018): Occurrence and diversity of arthropod-transmitted pathogens in red foxes (Vulpes vulpes) in western Austria, and possible vertical (transplacental) transmission of Hepatozoon canis. Parasitology 145, 335344.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Janjić, F. , Sarvan, D. , Tomanović, S. , Ćuk, J. , Krstić, V. , Radonjić, V. , Kovačević Filipović, M. and Ajtić, J. (2019): A short-term and long-term relationship between occurrence of acute canine babesiosis and meteorological parameters in Belgrade, Serbia. Ticks Tick Borne Dis. 10, 101273.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Jongejan, F. , Su, B. L. , Yang, H. J. , Berger, L. , Bevers, J. , Liu, P. C. , Fang, J. C. , Cheng, Y. W. , Kraakman, C. and Plaxton, N. (2018): Molecular evidence for the transovarial passage of Babesia gibsoni in Haemaphysalis hystricis (Acari: Ixodidae) ticks from Taiwan: a novel vector for canine babesiosis. Parasit. Vectors 11, 134.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Kirk, K. , Levy, J. K. and Crawford, P. C. (2017): Efficacy of azithromycin and compounded atovaquone for treatment of Babesia gibsoni in dogs. J. Vet. Intern. Med. 31, 11081112.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Kuo, C. , Zhao, C. , Cheng, T. , Tsou, C. , Li, Y. , Zhang, Y. , Hsieh, M. , Haung, S. and Chen, W. (2020): Rapid identification of Babesia canis and Babesia gibsoni (Asian genotype) in canine blood samples using a customized portable real-time PCR analyzer and TaqMan-based assay. Ticks Tick Borne Dis. 11, 101362.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Leschnik, M. (2020): Focus on common small animal vector-borne diseases in central and southeastern Europe. Acta Vet. Beograd 70, 147169.

  • Leschnik, M. W. , Khanakah, G. , Duscher, G. , Wille-Piazzai, W. , Hörweg, C. , Joachim, A. and Stanek, G. (2012): Species, developmental stage and infection with microbial pathogens of engorged ticks removed from dogs and questing ticks. Med. Vet. Entomol. 26, 440446.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Łyp, P. , Adaszek, Ł. , Furmaga, B. and Winiarczyk, S. (2015): Identification of new 18S rRNA strains of Babesia canis isolated from dogs with subclinical babesiosis. Polish J. Vet. Sci. 18, 573577.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Matsuu, A. , Miyamoto, K. , Ikadai, H. , Okano, S. and Higuchi, S. (2006): Short report: cloning of the Babesia gibsoni cytochrome B gene and isolation of three single nucleotide polymorphisms from parasites present after atovaquone treatment. Am. J. Trop. Med. Hyg. 74, 593597.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Miró, G. , Checa, R. , Paparini, A. , Ortega, N. , González-Fraga, J. L. , Gofton, A. , Bartolomé, A. , Montoya, A. , Gálvez, R. , Mayo, P. P. and Irwin, P. (2015): Theileria annae (syn. Babesia microti-like) infection in dogs in NW Spain detected using direct and indirect diagnostic techniques: clinical report of 75 cases. Parasit. Vectors 8, 217.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Pantchev, N. , Pluta, S. , Huisinga, E. , Nather, S. , Scheufelen, M. , Globokar Vrhovec, M. , Schweinitz, A. , Hampel, H. and Straubinger, R. K. (2015): Tick-borne diseases (borreliosis, anaplasmosis, babesiosis) in German and Austrian dogs: Status quo and review of distribution, transmission, clinical findings, diagnostics and prophylaxis. J. Parasitol. Res. 114, (Suppl. 1), S19S54.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Potkonjak, A. , Gutiérrez, R. , Savić, S. , Vračar, V. , Nachum-Biala, Y. , Jurišić, A. , Kleinerman, G. , Rojas, A. , Petrović, A. , Baneth, G. and Harrus, S. (2016): Molecular detection of emerging tick-borne pathogens in Vojvodina, Serbia. Ticks Tick Borne Dis. 7, 199203.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Potkonjak, A. , Savić, S. , Spasojević Kosić, L. , Tasić Otašević, S. , Tomanović, S. and Kovacevic Filipovic, M. (2020): Consensus statement on epidemiological situation and expected frequency of canine vector-borne diseases in Serbia. Vet. Glas. 74, 211215.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • René-Martellet, M. , Chêne, J. , Chabanne, L. , Chalvet-Monfray, K. and Bourdoiseau, G. (2013): Clinical signs, seasonal occurrence and causative agents of canine babesiosis in France: results of a multiregional study. Vet. Parasitol. 197, 5058.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • René-Martellet, M. , Moro, C. , Chêne, J. , Bourdoiseau, G. , Chabanne, L. and Mavingui, P. (2015): Update on epidemiology of canine babesiosis in Southern France. BMC Vet. Res. 11, 223.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Solano-Gallego, L. and Baneth, G. (2011): Babesiosis in dogs and cats – expanding parasitological and clinical spectra. Vet. Parasitol. 181, 4860.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Solano-Gallego, L. , Sainz, Á. , Roura, X. , Estrada-Peña, A. and Miró, G. (2016): A review of canine babesiosis: the European perspective. Parasit. Vectors 9, 336.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Sonnberger, B. , Graf, B. , Straubinger, R. , Rackl, D. , Obwaller, A. , Peschke, R. , Shahi Barogh, B. , Joachim, A. and Fuehrer, H. P. (2021): Vector-borne pathogens in clinically healthy military working dogs in eastern Austria. Parasitol. Int. 84, 102410.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Teodorowski, O. , Kalinowski, M. , Skrzypczak, M. , Witt, K. , Madany, J. , Winiarczyk, S. and Adaszek, Ł. (2020): Babesia gibsoni infection in dogs in Poland. Polish J. Vet. Sci. 23, 469471.

    • Search Google Scholar
    • Export Citation
  • Wahlang, L. , Lakshmanan, B. , Thomas, N. , Bosewell, A. , Jain Jose, K. , Sunanda C. and Aravindakshan, T. V. (2019): Comparative analysis of conventional and real-time PCR for detection of haemoparasites in dogs. Indian J. Biotechnol. 18, 915.

    • Search Google Scholar
    • Export Citation
  • Yao, D. W. , Jiang, J. Y. , Yu, Z. Z. , Yao, D. Q. , Yang, D. J. and Zhao, Y. B. (2014): Canine babesiosis in China caused by Babesia gibsoni: A molecular approach. Iranian J. Parasitol. 9, 163168.

    • Search Google Scholar
    • Export Citation
  • Zahler, M. , Schein, E. , Rinder, H. and Gothe, R. (1998): Characteristic genotypes discriminate between Babesia canis isolates of differing vector specificity and pathogenicity to dogs. Parasitol. Res. 84, 544.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Zintl, A. , Finnerty, E. J. , Murphy, T. M. , de Waal, T. and Gray, J. S. (2011): Babesias of red deer (Cervus elaphus) in Ireland. Vet. Res. 42, 7.

    • Crossref
    • Search Google Scholar
    • Export Citation

Author information is available in PDF.
Please, download the file from HERE.

The manuscript preparation instructions is available in PDF.
Please, download the file from HERE.

Senior editors

Editor-in-Chief: Mária BENKŐ

Managing Editor: András SZÉKELY

Editorial Board

  • Béla DÉNES (National Food Chain Safety Office, Budapest Hungary)
  • Edit ESZTERBAUER (Veterinary Medical Research Institute, Budapest, Hungary)
  • Hedvig FÉBEL (National Agricultural Innovation Centre, Herceghalom, Hungary)
  • László FODOR (University of Veterinary Medicine, Budapest, Hungary)
  • Balázs HARRACH (Veterinary Medical Research Institute, Budapest, Hungary)
  • Peter MASSÁNYI (Slovak University of Agriculture in Nitra, Nitra, Slovak Republic)
  • Béla NAGY (Veterinary Medical Research Institute, Budapest, Hungary)
  • Tibor NÉMETH (University of Veterinary Medicine, Budapest, Hungary)
  • Zsuzsanna NEOGRÁDY (University of Veterinary Medicine, Budapest, Hungary)
  • Alessandra PELAGALLI (University of Naples Federico II, Naples, Italy)
  • Kurt PFISTER (Ludwig-Maximilians-University of Munich, Munich, Germany)
  • László SOLTI (University of Veterinary Medicine, Budapest, Hungary)
  • József SZABÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Péter VAJDOVICH (University of Veterinary Medicine, Budapest, Hungary)
  • János VARGA (University of Veterinary Medicine, Budapest, Hungary)
  • Štefan VILČEK (University of Veterinary Medicine in Kosice, Kosice, Slovak Republic)
  • Károly VÖRÖS (University of Veterinary Medicine, Budapest, Hungary)
  • Herbert WEISSENBÖCK (University of Veterinary Medicine, Vienna, Austria)
  • Attila ZSARNOVSZKY (Szent István University, Gödöllő, Hungary)

ACTA VETERINARIA HUNGARICA
Institute for Veterinary Medical Research
Centre for Agricultural Research
Hungarian Academy of Sciences
P.O. Box 18, H-1581 Budapest, Hungary
Phone: (36 1) 467 4081 (ed.-in-chief) or (36 1) 213 9793 (editor) Fax: (36 1) 467 4076 (ed.-in-chief) or (36 1) 213 9793

Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • Chemical Abstracts
  • Current Contents: Agriculture, Biology and Environmental Sciences
  • Elsevier Science Navigator
  • Focus On: Veterinary Science and Medicine
  • Global Health
  • Index Medicus
  • Index Veterinarius
  • Medline
  • Science Citation Index
  • Science Citation Index Expanded (SciSearch)
  • SCOPUS
  • The ISI Alerting Services
  • Zoological Abstracts

 

2020  
Total Cites 987
WoS
Journal
Impact Factor
0,955
Rank by Veterinary Sciences 101/146 (Q3)
Impact Factor  
Impact Factor 0,920
without
Journal Self Cites
5 Year 1,164
Impact Factor
Journal  0,57
Citation Indicator  
Rank by Journal  Veterinary Sciences 93/166 (Q3)
Citation Indicator   
Citable 49
Items
Total 49
Articles
Total 0
Reviews
Scimago 33
H-index
Scimago 0,395
Journal Rank
Scimago Veterinary (miscellaneous) Q2
Quartile Score  
Scopus 355/217=1,6
Scite Score  
Scopus General Veterinary 73/183 (Q2)
Scite Score Rank  
Scopus 0,565
SNIP  
Days from  145
submission  
to acceptance  
Days from  150
acceptance  
to publication  
Acceptance 19%
Rate

 

2019  
Total Cites
WoS
798
Impact Factor 0,991
Impact Factor
without
Journal Self Cites
0,897
5 Year
Impact Factor
1,092
Immediacy
Index
0,119
Citable
Items
59
Total
Articles
59
Total
Reviews
0
Cited
Half-Life
9,1
Citing
Half-Life
9,2
Eigenfactor
Score
0,00080
Article Influence
Score
0,253
% Articles
in
Citable Items
100,00
Normalized
Eigenfactor
0,09791
Average
IF
Percentile
42,606
Scimago
H-index
32
Scimago
Journal Rank
0,372
Scopus
Scite Score
335/213=1,6
Scopus
Scite Score Rank
General Veterinary 62/178 (Q2)
Scopus
SNIP
0,634
Acceptance
Rate
18%

 

Acta Veterinaria Hungarica
Publication Model Hybrid
Submission Fee none
Article Processing Charge 1100 EUR/article
Printed Color Illustrations 40 EUR (or 10 000 HUF) + VAT / piece
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription fee 2022 Online subsscription: 710 EUR / 892 USD
Print + online subscription: 824 EUR / 1028 USD
Subscription Information Online subscribers are entitled access to all back issues published by Akadémiai Kiadó for each title for the duration of the subscription, as well as Online First content for the subscribed content.
Purchase per Title Individual articles are sold on the displayed price.

Acta Veterinaria Hungarica
Language English
Size A4
Year of
Foundation
1951
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-6290 (Print)
ISSN 1588-2705 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Aug 2021 0 0 0
Sep 2021 0 0 0
Oct 2021 0 0 0
Nov 2021 0 0 0
Dec 2021 104 12 14
Jan 2022 43 20 10
Feb 2022 0 0 0