Authors:
Mehmet Akif Kilinc Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Bingöl University, 12000 Merkez/Bingöl, Turkey

Search for other papers by Mehmet Akif Kilinc in
Current site
Google Scholar
PubMed
Close
https://orcid.org/0000-0003-1577-1556
and
Ali Risvanli Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Kyrgyz-Turkish Manas University, Bishkek, Kyrgyzstan

Search for other papers by Ali Risvanli in
Current site
Google Scholar
PubMed
Close
Restricted access

Abstract

The aim of the present study was to determine asprosin levels in cows, the relationship of this hormone with postpartum disorders and β-hydroxybutyric acid, and also the potential of asprosin to be a marker for postpartum diseases. The study was designed as a two-stage trial. In the first stage, blood asprosin and β-hydroxybutyric acid levels of 20 healthy Simmental cows aged 3–4 years were measured at the time of calving, and on days 3, 6, 9, 12 and 15 postpartum. In the second stage, 200 cows were divided into two groups: (1) healthy (n = 100) and (2) diseased (placental retention, hypocalcaemia, metritis, lameness, abomasal displacement, mastitis; n = 100); asprosin and β-hydroxybutyric acid concentrations of the blood were assessed on day 15 postpartum. In conclusion, the asprosin level was found to be at measurable levels in cows, and a negative correlation with β-hydroxybutyric acid was found. According to these findings, the data obtained from this study could be used for the prevention, control and treatment of some postpartum disorders associated with ketosis and for developing novel hypotheses concerning the actions of this hormone. It was concluded that further studies are required to reveal the associations between asprosin and postpartum disorders.

  • Abdelli, A. , Raboisson, D. , Kaidi, R. , Ibrahim, B. , Kalem, A. and Iguer-Ouada, M. (2017): Elevated non-esterified fatty acid and β-hydroxybutyrate in transition dairy cows and their association with reproductive performance and disorders: a meta-analysis. Theriogenology 93 ,99104.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Alan, M. , Gurlek, B. , Yilmaz, A. , Aksit, M. , Aslanipour, B. , Gulhan, I. , Mehmet, C. and Taner, C. E. (2019): Asprosin: a novel peptide hormone related to insulin resistance in women with polycystic ovary syndrome. Gynecol. Endocrinol. 35, 220223.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Bach, K. D. , Heuwieser, W. and McArt, J. A. A. (2016): Technical note: comparison of 4 electronic handheld meters for diagnosing hyperketonemia in dairy cows. J. Dairy Sci. 99, 91369142.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Bastan, A. and Gürbulak, G. (2012): Metabolic disorders. In: Semacan, A. , Kaymaz, M. , Fındık, M. , Rişvanlı, A. and Köker, A. (eds) Farm Animal Obstetrics and Gynecology [in Turkish]. Medipres, Malatya. pp. 469506.

    • Search Google Scholar
    • Export Citation
  • Booth, A. , Magnuson, A. , Fouts, J. and Foster, M. T. (2016): Adipose tissue: an endocrine organ playing a role in metabolic regulation. Horm. Mol. Biol. Clin. Investig. 26 ,2542.

    • Search Google Scholar
    • Export Citation
  • Chapinal, N. , Carson, M. , Duffield, T. , Capel, M. , Godden, S. , Overton, M. , Santos, J. and LeBlanc, S. (2011): The association of serum metabolites with clinical disease during the transition period. J. Dairy Sci. 94 ,48974903.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Dohoo, I. R. and Martin, S. (1984): Subclinical ketosis: prevalence and associations with production and disease. Can. J. Comp. Med. 48 ,1.

    • Search Google Scholar
    • Export Citation
  • Drackley, J. K. (1999): Biology of dairy cows during the transition period: The final frontier? J. Dairy Sci. 82 ,22592273.

  • Duerrschmid, C. , He, Y. , Wang, C. , Li, C. , Bournat, J. C. , Romere, C. , Saha, P. K. , Lee, M. E. , Phillips, K. J. and Jain, M. (2017): Asprosin is a centrally acting orexigenic hormone. Nat. Med. 23 ,1444.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Duffield, T. , Bagg, R. , DesCoteaux, L. , Bouchard, E. , Brodeur, M. , DuTremblay, D. , Keefe, G. , LeBlanc, S. and Dick, P. (2002): Prepartum monensin for the reduction of energy associated disease in postpartum dairy cows. J. Dairy Sci. 85 ,397405.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Duffield, T. , Lissemore, K. , McBride, B. and Leslie, K. (2009): Impact of hyperketonemia in early lactation dairy cows on health and production. J. Dairy Sci. 92 ,571580.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Fiorentin, E. L. , Tiecher, A. , Menegat, C. , Soares, C. , Aires, A. , Rocha, R. and Gonzalez, F. H. D. (2017): Accuracy of two hand-held electronic devices for determination of blood β-hydroxybutyrate in dairy cows. Rev. Bras. Saude Prod. Anim. 18 ,439445.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Geishauser, T. , Leslie, K. , Kelton, D. and Duffield, T. (2001): Monitoring for subclinical ketosis in dairy herds. Compendium 23 ,6571.

    • Search Google Scholar
    • Export Citation
  • Grummer, R. R. (1995): Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. J. Anim. Sci. 73 ,28202833.

  • Ingvartsen, K. L. (2006): Feeding- and management-related diseases in the transition cow: Physiological adaptations around calving and strategies to reduce feeding-related diseases. Anim. Feed Sci. Technol. 126 ,175213.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Kaufmann, T. B. , Drillich, M. , Tenhagen, B. A. and Heuwieser, W. (2010): Correlations between periparturient serum concentrations of non-esterified fatty acids, beta-hydroxybutyric acid, bilirubin, and urea and the occurrence of clinical and subclinical postpartum bovine endometritis. BMC Vet. Res. 6 ,16.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Kremer, W. , Noordhuizen-Stassen, E. , Grommers, F. , Schukken, Y. , Heeringa, R. , Brand, A. and Burvenich, C. (1993): Severity of experimental Escherichia coli mastitis in ketonemic and nonketonemic dairy cows. J. Dairy Sci. 76 ,34283436.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Leal Yepes, F. A. , Nydam, D. V. , Heuwieser, W. and Mann, S. (2018): Technical note: Evaluation of the diagnostic accuracy of 2 point-of-care β-hydroxybutyrate devices in stored bovine plasma at room temperature and at 37 °C. J. Dairy Sci. 101 ,64556461.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • LeBlanc, S. , Leslie, K. and Duffield, T. (2005): Metabolic predictors of displaced abomasum in dairy cattle. J. Dairy Sci. 88 ,159170.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Maylem, E. R. S. , Spicer, L. J. , Batalha, I. and Schutz, L. F. (2021): Discovery of a possible role of asprosin in ovarian follicular function. J. Mol. Endocrinol. 66 ,3544.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Ospina, P. , Nydam, D. , Stokol, T. and Overton, T. (2010): Association between the proportion of sampled transition cows with increased nonesterified fatty acids and β-hydroxybutyrate and disease incidence, pregnancy rate, and milk production at the herd level. J. Dairy Sci. 93 ,35953601.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Romere, C. , Duerrschmid, C. , Bournat, J. , Constable, P. , Jain, M. , Xia, F. , Saha, P. K. , Del Solar, M. , Zhu, B. and York, B. (2016): Asprosin, a fasting-induced glucogenic protein hormone. Cell 165 ,566579.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Suthar, V. , Canelas-Raposo, J. , Deniz, A. and Heuwieser, W. (2013): Prevalence of subclinical ketosis and relationships with postpartum diseases in European dairy cows. J. Dairy Sci. 96 ,29252938.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Ugur, K. and Aydin, S. (2019): Saliva and blood asprosin hormone concentration associated with obesity. Int. J. Endocrinol. 2019 ,18.

  • Zhang, L. , Chen, C. , Zhou, N. , Fu, Y. and Cheng, X. (2019): Circulating asprosin concentrations are increased in type 2 diabetes mellitus and independently associated with fasting glucose and triglyceride. Clin. Chim. Acta 489 ,183188.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Collapse
  • Expand
Author informations are available in PDF.
Please, download the file from HERE

 

The manuscript preparation instructions are available in PDF.
Please, download the file from HERE

 

Senior editors

Editor-in-Chief: Ferenc BASKA

Editorial assistant: Szilvia PÁLINKÁS

 

Editorial Board

  • Mária BENKŐ (Acta Veterinaria Hungarica, Budapest, Hungary)
  • Gábor BODÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Béla DÉNES (University of Veterinary Medicine, Budapest Hungary)
  • Edit ESZTERBAUER (Veterinary Medical Research Institute, Budapest, Hungary)
  • Hedvig FÉBEL (National Agricultural Innovation Centre, Herceghalom, Hungary)
  • László FODOR (University of Veterinary Medicine, Budapest, Hungary)
  • János GÁL (University of Veterinary Medicine, Budapest, Hungary)
  • Balázs HARRACH (Veterinary Medical Research Institute, Budapest, Hungary)
  • Peter MASSÁNYI (Slovak University of Agriculture in Nitra, Nitra, Slovak Republic)
  • Béla NAGY (Veterinary Medical Research Institute, Budapest, Hungary)
  • Tibor NÉMETH (University of Veterinary Medicine, Budapest, Hungary)
  • Zsuzsanna NEOGRÁDY (University of Veterinary Medicine, Budapest, Hungary)
  • Dušan PALIĆ (Ludwig Maximilian University, Munich, Germany)
  • Alessandra PELAGALLI (University of Naples Federico II, Naples, Italy)
  • Kurt PFISTER (Ludwig-Maximilians-University of Munich, Munich, Germany)
  • László SOLTI (University of Veterinary Medicine, Budapest, Hungary)
  • József SZABÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Péter VAJDOVICH (University of Veterinary Medicine, Budapest, Hungary)
  • János VARGA (University of Veterinary Medicine, Budapest, Hungary)
  • Štefan VILČEK (University of Veterinary Medicine in Kosice, Kosice, Slovak Republic)
  • Károly VÖRÖS (University of Veterinary Medicine, Budapest, Hungary)
  • Herbert WEISSENBÖCK (University of Veterinary Medicine, Vienna, Austria)
  • Attila ZSARNOVSZKY (Szent István University, Gödöllő, Hungary)

ACTA VETERINARIA HUNGARICA
Institute for Veterinary Medical Research
Centre for Agricultural Research
Hungarian Academy of Sciences
P.O. Box 18, H-1581 Budapest, Hungary
Phone: (36 1) 287 7073 (ed.-in-chief) or (36 1) 467 4081 (editor)

E-mail: acta.veterinaria@univet.hu (ed.-in-chief)

Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • Chemical Abstracts
  • Current Contents: Agriculture, Biology and Environmental Sciences
  • Elsevier Science Navigator
  • Focus On: Veterinary Science and Medicine
  • Global Health
  • Index Medicus
  • Index Veterinarius
  • Medline
  • Science Citation Index
  • Science Citation Index Expanded (SciSearch)
  • SCOPUS
  • The ISI Alerting Services
  • Zoological Abstracts

 

2023  
Web of Science  
Journal Impact Factor 0.7
Rank by Impact Factor Q3 (Veterinary Sciences)
Journal Citation Indicator 0.4
Scopus  
CiteScore 1.8
CiteScore rank Q2 (General Veterinary)
SNIP 0.39
Scimago  
SJR index 0.258
SJR Q rank Q3

Acta Veterinaria Hungarica
Publication Model Hybrid
Submission Fee none
Article Processing Charge 1100 EUR/article
Printed Color Illustrations 40 EUR (or 10 000 HUF) + VAT / piece
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription fee 2025 Online subsscription: 832 EUR / 916 USD
Print + online subscription: 960 EUR / 1054 USD
Subscription Information Online subscribers are entitled access to all back issues published by Akadémiai Kiadó for each title for the duration of the subscription, as well as Online First content for the subscribed content.
Purchase per Title Individual articles are sold on the displayed price.

Acta Veterinaria Hungarica
Language English
Size A4
Year of
Foundation
1951
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-6290 (Print)
ISSN 1588-2705 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Feb 2024 42 1 0
Mar 2024 27 2 0
Apr 2024 56 1 1
May 2024 37 0 0
Jun 2024 28 1 1
Jul 2024 60 0 0
Aug 2024 0 0 0