Authors:
Estefanía Sereno-Bruno Instituto de Ciencias de la Tierra y Ambientales de La Pampa (Consejo Nacional de Investigaciones Científicas y Técnicas – Facultad de Ciencias Naturales Universidad Nacional de La Pampa), Santa Rosa, La Pampa, Argentina

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Lumila Fuchs Instituto Nacional de Tecnología Agropecuaria, Anguil, La Pampa, Argentina

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Jorge Oyhenart Instituto de Ciencias de la Tierra y Ambientales de La Pampa (Consejo Nacional de Investigaciones Científicas y Técnicas – Facultad de Ciencias Naturales Universidad Nacional de La Pampa), Santa Rosa, La Pampa, Argentina

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Abstract

There are no recommended drugs to treat cattle infected with the protozoan Tritrichomonas foetus (TF). Ivermectin, widely used in the treatment of intestinal parasites, was found effective against some protozoa growing in vitro. Here, its effectiveness against a TF line was investigated. Trophozoites were incubated in media with increasing concentrations of ivermectin and mortality was determined after 24 h. Ivermectin killed cells with a mean maximum effective concentration (EC50) of 2.47 μg mL−1. The effective concentration of ivermectin was rather high for a formulation suitable for systemic treatment. However, topical treatment of animals against TF could still be considered and tested.

  • Baltzell, P., Newton, H. and O’Connor, A. M. (2013): A critical review and meta-analysis of the efficacy of whole-cell killed Tritrichomonas foetus vaccines in beef cattle. J. Vet. Intern. Med. 27, 760770. https://doi.org/10.1111/jvim.12112.

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  • Bondurant, R. H. (2005): Venereal diseases of cattle: natural history, diagnosis, and the role of vaccines in their control. Vet. Clin. North Am. Food Anim. Pract. 21, 383408. https://doi.org/10.1016/j.cvfa.2005.03.002.

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    • Export Citation
  • Castro Rodrigues, D., Buzullini C., Arantes Pereira T., Cayeiro Curz B., Vinicius Costa Gomes L., Edésio Soares V., Souza Azeredo Bastos T., Monteiro L., Zanetti Lopes W., Pereira de Oliveira G. and da Costa A. (2018): Avermectin toxicity in bovines less than thirty days old. Res. Vet. Sci. 118:403-412. https://doi.org/10.1016/j.rvsc.2018.04.003.

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  • Clark, N., Hafner, M., Kouril, M., Muhlich, J., Niepel, M., Williams, E., Sorger, P. and Medvedovic, M. (2016): GRcalculator: an online tool for calculating and mining drug response data. Available: https://figshare.com/articles/poster/GRcalculator_an_online_tool_for_calculating_and_mining_drug_response_data/4244408/1. https://doi.org/10.6084/m9.figshare.4244408.v1.

    • Search Google Scholar
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  • Crump, A. (2017): Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations. J. Antibiot. 70, 495505. https://doi.org/10.1038/ja.2017.11.

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  • Formiga, F. R., Leblanc, R., de Souza Rebouças, J., Farias, L. P., de Oliveira, R. N. and Pena, L. (2021): Ivermectin: an award-winning drug with expected antiviral activity against COVID-19. J. Contr. Release 329, 758761. https://doi.org/10.1016/j.jconrel.2020.10.009.

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  • González-Salazar, F., Mata-Cárdenas, B. D., Rivera Silva, G., Garza-González, J. N., Cortes-Gutiérrez, E. I. and Vargas-Villarreal, J. (2012): In vitro effects of ivermectin upon Trichomonas vaginalis trophozoites. Lat. Am. J. Pharm. 31, 156158.

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  • Hafner, M., Niepel, M., Chung, M. and Sorger, P. K. (2016): Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs. Nat. Methods 13, 521527. https://doi.org/10.1038/nmeth.3853.

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  • Hashemi, N., Ommi, D., Kheyri, P., Khamesipour, F., Setzer, W. N. and Benchimol, M. (2021): A review study on the anti-trichomonas activities of medicinal plants. Int. J. Parasitol. Drugs Drug Resist. 15, 92104. https://doi.org/10.1016/j.ijpddr.2021.01.002.

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  • Katz, N., Araújo, N., Coelho, P. M. Z., Morel, C. M., Linde-Arias, A. R., Yamada, T., Horimatsu, Y., Suzuki, K., Sunazuka, T. and Ōmura, S. (2017): Ivermectin efficacy against Biomphalaria, intermediate host snail vectors of Schistosomiasis. J. Antibiot. 70, 680684. https://doi.org/10.1038/ja.2017.31.

    • Search Google Scholar
    • Export Citation
  • Kimsey, P. B., Darien, B. J., Kendrick, J. W. and Franti, C. E. (1980): Bovine trichomoniasis: diagnosis and treatment. J. Am. Vet. Med. Assoc. 177, 616619.

    • Search Google Scholar
    • Export Citation
  • Love, D., Fajt, V. R., Hairgrove, T., Jones, M. and Thompson, J. A. (2017): Metronidazole for the treatment of Tritrichomonas foetus in bulls. BMC Vet. Res. 13, 107. https://doi.org/10.1186/s12917-017-0999-2.

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  • Martin, K. A., Henderson, J. and Brewer, M. T. (2021): Bovine trichomonosis cases in the United States 2015-2019. Front. Vet. Sci. 8, 692199. https://doi.org/10.3389/fvets.2021.692199.

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  • Martinez, F. G., Fuchs, L., Ramirez, R., Breccia, J. and Oyhenart, J. (2018): Evaluation of Tritrichomonas foetus infection clearance in heifers immunized with a single intravaginal dose of formaldehyde fixed strain B1 cells. Vet. Parasitol. 255, 3237. https://doi.org/10.1016/j.vetpar.2018.03.019.

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  • Oyhenart, J. (2020): Retrospective cohort study for the identification of true-positive farms over 12-year of enforced program for Tritrichomonas foetus eradication in La Pampa, Argentina. Vet. Parasitol. Reg. Stud. Rep. 22, 100498. https://doi.org/10.1016/j.vprsr.2020.100498.

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  • Reis, T. A. R., Oliveira-da-Silva, J. A., Tavares, G. S. V., Mendonça, D. V. C., Freitas, C. S., Costa, R. R., Lage, D. P., Martins, V. T., Machado, A. S., Ramos, F. F., Silva, A. M., Ludolf, F., Antinarelli, L. M. R., Brito, R. C. F., Chávez-Fumagalli, M. A., Humbert, M. V., Roatt, B. M., Coimbra, E. S. and Coelho, E. A. F. (2021): Ivermectin presents effective and selective antileishmanial activity in vitro and in vivo against Leishmania infantum and is therapeutic against visceral leishmaniasis. Exp. Parasitol. 221, 108059. https://doi.org/10.1016/j.exppara.2020.108059.

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  • Skirrow, S., BonDurant, R., Farley, J. and Correa, J. (1985): Efficacy of ipronidazole against trichomoniasis in beef bulls. J. Am. Vet. Med. Assoc. 187, 405407.

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  • World Assembly, of Delegates of the OIE (2018): Trichomonosis. Office of International Epizootics, chapter 3.4.15.

  • Yao, C. (2021): Control and eradication of bovine trichomonosis in Wyoming, USA by testing and culling positive bulls. Vet. Res. 52, 129. https://doi.org/10.1186/s13567-021-00996-w.

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Senior editors

Editor-in-Chief: Ferenc BASKA

Editorial assistant: Szilvia PÁLINKÁS

 

Editorial Board

  • Mária BENKŐ (Acta Veterinaria Hungarica, Budapest, Hungary)
  • Gábor BODÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Béla DÉNES (University of Veterinary Medicine, Budapest Hungary)
  • Edit ESZTERBAUER (Veterinary Medical Research Institute, Budapest, Hungary)
  • Hedvig FÉBEL (National Agricultural Innovation Centre, Herceghalom, Hungary)
  • László FODOR (University of Veterinary Medicine, Budapest, Hungary)
  • János GÁL (University of Veterinary Medicine, Budapest, Hungary)
  • Balázs HARRACH (Veterinary Medical Research Institute, Budapest, Hungary)
  • Peter MASSÁNYI (Slovak University of Agriculture in Nitra, Nitra, Slovak Republic)
  • Béla NAGY (Veterinary Medical Research Institute, Budapest, Hungary)
  • Tibor NÉMETH (University of Veterinary Medicine, Budapest, Hungary)
  • Zsuzsanna NEOGRÁDY (University of Veterinary Medicine, Budapest, Hungary)
  • Dušan PALIĆ (Ludwig Maximilian University, Munich, Germany)
  • Alessandra PELAGALLI (University of Naples Federico II, Naples, Italy)
  • Kurt PFISTER (Ludwig-Maximilians-University of Munich, Munich, Germany)
  • László SOLTI (University of Veterinary Medicine, Budapest, Hungary)
  • József SZABÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Péter VAJDOVICH (University of Veterinary Medicine, Budapest, Hungary)
  • János VARGA (University of Veterinary Medicine, Budapest, Hungary)
  • Štefan VILČEK (University of Veterinary Medicine in Kosice, Kosice, Slovak Republic)
  • Károly VÖRÖS (University of Veterinary Medicine, Budapest, Hungary)
  • Herbert WEISSENBÖCK (University of Veterinary Medicine, Vienna, Austria)
  • Attila ZSARNOVSZKY (Szent István University, Gödöllő, Hungary)

ACTA VETERINARIA HUNGARICA
Institute for Veterinary Medical Research
Centre for Agricultural Research
Hungarian Academy of Sciences
P.O. Box 18, H-1581 Budapest, Hungary
Phone: (36 1) 287 7073 (ed.-in-chief) or (36 1) 467 4081 (editor)

E-mail: acta.veterinaria@univet.hu (ed.-in-chief)

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2022  
Web of Science  
Total Cites
WoS
972
Journal Impact Factor 0.900
Rank by Impact Factor

Veterinary Sciences 95/143

Impact Factor
without
Journal Self Cites
0.900
5 Year
Impact Factor
1.1
Journal Citation Indicator 0.47
Rank by Journal Citation Indicator

Veterinary Sciences 103/170

Scimago  
Scimago
H-index
38
Scimago
Journal Rank
0.277
Scimago Quartile Score

Veterinary (miscellaneous) Q2

Scopus  
Scopus
Cite Score
1.9
Scopus
CIte Score Rank
General Veterinary 76/186 (59th PCTL)
Scopus
SNIP
0.475

2021  
Web of Science  
Total Cites
WoS
1040
Journal Impact Factor 0,959
Rank by Impact Factor Veterinary Sciences 103/144
Impact Factor
without
Journal Self Cites
0,876
5 Year
Impact Factor
1,222
Journal Citation Indicator 0,48
Rank by Journal Citation Indicator Veterinary Sciences 106/168
Scimago  
Scimago
H-index
36
Scimago
Journal Rank
0,313
Scimago Quartile Score Veterinary (miscellaneous) (Q2)
Scopus  
Scopus
Cite Score
1,7
Scopus
CIte Score Rank
General Veterinary 79/183 (Q2)
Scopus
SNIP
0,610

2020  
Total Cites 987
WoS
Journal
Impact Factor
0,955
Rank by Veterinary Sciences 101/146 (Q3)
Impact Factor  
Impact Factor 0,920
without
Journal Self Cites
5 Year 1,164
Impact Factor
Journal  0,57
Citation Indicator  
Rank by Journal  Veterinary Sciences 93/166 (Q3)
Citation Indicator   
Citable 49
Items
Total 49
Articles
Total 0
Reviews
Scimago 33
H-index
Scimago 0,395
Journal Rank
Scimago Veterinary (miscellaneous) Q2
Quartile Score  
Scopus 355/217=1,6
Scite Score  
Scopus General Veterinary 73/183 (Q2)
Scite Score Rank  
Scopus 0,565
SNIP  
Days from  145
submission  
to acceptance  
Days from  150
acceptance  
to publication  
Acceptance 19%
Rate

 

2019  
Total Cites
WoS
798
Impact Factor 0,991
Impact Factor
without
Journal Self Cites
0,897
5 Year
Impact Factor
1,092
Immediacy
Index
0,119
Citable
Items
59
Total
Articles
59
Total
Reviews
0
Cited
Half-Life
9,1
Citing
Half-Life
9,2
Eigenfactor
Score
0,00080
Article Influence
Score
0,253
% Articles
in
Citable Items
100,00
Normalized
Eigenfactor
0,09791
Average
IF
Percentile
42,606
Scimago
H-index
32
Scimago
Journal Rank
0,372
Scopus
Scite Score
335/213=1,6
Scopus
Scite Score Rank
General Veterinary 62/178 (Q2)
Scopus
SNIP
0,634
Acceptance
Rate
18%

 

Acta Veterinaria Hungarica
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Acta Veterinaria Hungarica
Language English
Size A4
Year of
Foundation
1951
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-6290 (Print)
ISSN 1588-2705 (Online)

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