Authors:
Piotr Cybulski Goodvalley Agro S.A., Dworcowa 25, 77-320 Przechlewo, Poland

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Katrin Strutzberg-Minder IVD Gesellschaft für Innovative Veterinärdiagnostik mbH, 30926 Seelze-Letter, Germany

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Edyta Michalik Goodvalley Agro S.A., Dworcowa 25, 77-320 Przechlewo, Poland

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Radosław Kondratiuk Goodvalley Agro S.A., Dworcowa 25, 77-320 Przechlewo, Poland

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Artur Jabłoński Department of Pathology and Veterinary Diagnostics, Institute of Veterinary Medicine, Warsaw University of Life Sciences – SGGW, Nowoursynowska 159C, 02-776 Warsaw, Poland

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Abstract

Nowadays, the three strongly beta-haemolytic spirochaetes, Brachyspira hyodysenteriae, Brachyspira suanatina and Brachyspira hampsonii are thought to be causative agents of swine dysentery, an economically devastating disease of grow-finish pigs characterised by severe mucohaemorrhagic diarrhoea. B. hyodysenteriae has been reported in most leading swine-producing regions. B. suanatina and B. hampsonii have been successfully recovered from faecal samples collected in a few countries only. The present study was performed in March 2023 on faecal samples originating from nine Polish finisher farms with 6,000 to 18,000 animals in a location. Samples were obtained from 40 diarrhoeic finishers. Nucleic acid extracted from the samples was analysed using multiplex PCR for Brachyspira spp. From a total of nine sample populations examined in our study, the genetic material of B. hampsonii was identified in two. To the best of our knowledge, this is the first report on molecular detection of B. hampsonii on pig farms outside North America, Belgium and Germany. Our research highlights the need for increased focus directed on laboratory testing strategies, the lack of which may perplex swine practitioners and severely hinder a definite diagnosis.

  • Anonymous (2022): Animal and Plant Health Agency. Great Britain Pig Quarterly Report: Disease Surveillance and Emerging Threats. Volume 26: Quarter 2 of 2022 (April to June). APHA, Addlestone, United Kingdom. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1107082/2022_Q2_Pigs_final.pdf (accessed on 28 June 2023).

    • Search Google Scholar
    • Export Citation
  • Barcellos, D. E., Mathiesen, M. R., de Uzeda, M., Kader, I. I. and Duhamel, G. E. (2000): Prevalence of Brachyspira species isolated from diarrhoeic pigs in Brazil. Vet. Rec. 146, 398403.

    • Search Google Scholar
    • Export Citation
  • Boye, M., Baloda, S. B., Leser, T. D. and Møller, K. (2001): Survival of Brachyspira hyodysenteriae and B. pilosicoli in terrestrial microcosms. Vet. Microbiol. 81, 3340.

    • Search Google Scholar
    • Export Citation
  • Burrough, E. R., Strait, E. L., Kinyon, J. M., Bower, L. P., Madson, D. M., Wilberts, B. L., Schwartz, K. J., Frana, T. S. and Songer, J. G. (2012): Comparative virulence of clinical Brachyspira spp. isolates in inoculated pigs. J. Vet. Diagn. Invest. 24, 10251034.

    • Search Google Scholar
    • Export Citation
  • Chander, Y., Primus, A., Oliveira, S. and Gebhart, C. J. (2012): Phenotypic and molecular characterization of a novel strongly hemolytic Brachyspira species, provisionally designated “Brachyspira hampsonii. J. Vet. Diagnost Invest. 24, 903910.

    • Search Google Scholar
    • Export Citation
  • Cybulski, P., Strutzberg-Minder, K., Michalik, E., Kondratiuk, R. and Jabłoński, A. (2023): First molecular detection of Brachyspira suanatina on pig farms in Poland. J. Vet. Res. 67, 353359.

    • Search Google Scholar
    • Export Citation
  • Davis, A. J., Smith, S. C. and Moore, R. J. (2005): The Brachyspira hyodysenteriae ftnA gene: DNA vaccination and real-time PCR quantification of bacteria in a mouse model of disease. Curr. Microbiol. 50, 285291.

    • Search Google Scholar
    • Export Citation
  • Deplazes P., Eckert J., von Samson-Himmelstjerna G., Zahner H. and Teil V (2013): Diagnostik, In: Lehrbuch der Parasitologie für die Tiermedizin [in German], Enke Verlag, Stuttgart, pp. 508524.

    • Search Google Scholar
    • Export Citation
  • Dors, A., Czyżewska-Dors, E. and Woźniakowski, G. (2019): A survey on the occurrence of Brachyspira pilosicoli and Brachyspira hyodysenteriae in growing-finishing pigs. F1000Research 8, 1702.

    • Search Google Scholar
    • Export Citation
  • Duhamel, G. E. (2001): Comparative pathology and pathogenesis of naturally acquired and experimentally induced colonic spirochetosis. Anim. Health Res. Rev. 2, 317.

    • Search Google Scholar
    • Export Citation
  • Durmic, Z., Pethick, D. W., Mullan, B. P., Accioly, J. M., Schulze, H. and Hampson, D. J. (2002): Evaluation of large intestinal parameters associated with dietary treatments designed to reduce the occurrence of swine dysentery. Br. J. Nutr. 88, 159169.

    • Search Google Scholar
    • Export Citation
  • Fellström, C., Pettersson, B., Johansson, K. E., Lundeheim, N. and Gunnarsson, A. (1996): Prevalence of Serpulina species in relation to diarrhea and feed medication in pig-rearing herds in Sweden. Am. J. Vet. Res. 57, 807811.

    • Search Google Scholar
    • Export Citation
  • Hampson, J. D. and Burrough, E. R. (2019): Swine dysentery and brachyspiral colitis In: Diseases of Swine, 11th Edition. Editor(s): Jeffrey J. Zimmerman, Locke A. Karriker, Alejandro Ramirez, Kent J. Schwartz, Gregory W. Stevenson, Jianqiang Zhang. pp. 951970.

    • Search Google Scholar
    • Export Citation
  • Hampson, D. J., La, T. and Phillips, N. D. (2015): Emergence of Brachyspira species and strains: reinforcing the need for surveillance. Porc. Health Manag. 12, 18.

    • Search Google Scholar
    • Export Citation
  • Harris, D. L., Glock, R. D., Christensen, C. R. and Kinyon, J. M. (1972): Inoculation of pigs with Treponema hyodysenteriae (new species) and reproduction of the disease. Vet. Med. Sm. Anim. Clin. 67, 6164.

    • Search Google Scholar
    • Export Citation
  • Jacobson, M., Lindberg, R., Jonasson, R., Fellström, C. and Jensen-Waern, M. (2007): Consecutive pathological and immunological alterations during experimentally induced swine dysentery − a study performed by repeated endoscopy and biopsy samplings through an intestinal cannula. Res. Vet. Sci. 82, 287298.

    • Search Google Scholar
    • Export Citation
  • Jansson, D. S., Johansson, K. E., Olofsson, T., Råsbäck, T., Vågsholm, I., Pettersson B, Gunnarsson, A. and Fellström, C. (2004): Brachyspira hyodysenteriae and other strongly beta-haemolytic and indole-positive spirochaetes isolated from mallards (Anas platyrhynchos). J. Med. Microbiol. 53, 293300.

    • Search Google Scholar
    • Export Citation
  • Mahu, M., de Jong, E., De Pauw, N., Vande Maele, L., Vandenbroucke, V., Vandersmissen, T., Miry, C., Pasmans, F., Haesebrouck, F., Martel, A. and Boyen, F. (2014): First isolation of “Brachyspira hampsonii” from pigs in Europe. Vet. Rec. 174, 47.

    • Search Google Scholar
    • Export Citation
  • Martínez-Lobo, F. J., Hidalgo, Á., García, M., Argüello, H., Naharro, G., Carvajal, A. and Rubio, P. (2013): First identification of “Brachyspira hampsonii” in wild European waterfowl. PLoS One 8, e82626.

    • Search Google Scholar
    • Export Citation
  • Møller, K., Jensen, T. K., Jorsal, S. E., Leser, T. D. and Carstensen, B. (1998): Detection of Lawsonia intracellularis, Serpulina hyodysenteriae, weakly beta-hemolytic intestinal spirochaetes, Salmonella enterica, and Escherichia coli from swine herds with and without diarrhoea among growing pigs. Vet. Microbiol. 62, 5972.

    • Search Google Scholar
    • Export Citation
  • Neirynck, W., Boyen, F., Chantziaras, I., Vandersmissen, T., Vyt, P., Haesebrouck, F., Dewulf, J. and Maes, D. (2020): Implementation and evaluation of different eradication strategies for Brachyspira hyodysenteriae. Porc. Health Manag. 6, 27.

    • Search Google Scholar
    • Export Citation
  • Olson, L. D. (1995): Survival of Serpulina hyodysenteriae in an effluent lagoon. J. Am. Vet. Med. Assoc. 207, 14701472.

  • Patterson, A. H., Rubin, J. E., Fernando, C., Costa, M. O., Harding, J. C. and Hill, J. E. (2013) Fecal shedding of Brachyspira spp. on a farrow-to-finish swine farm with a clinical history of ‘‘Brachyspira hampsonii’’-associated colitis. BMC Vet. Res. 9, 137.

    • Search Google Scholar
    • Export Citation
  • Pluske, J. R., Siba, P. M., Pethick, D. W., Durmic, Z., Mullan, B. P. and Hampson, D. J. (1996): The incidence of swine dysentery in pigs can be reduced by feeding diets that limit the amount of fermentable substrate entering the large intestine. J. Nutr. 126, 29202933.

    • Search Google Scholar
    • Export Citation
  • Råsbäck, T., Jansson, D. S., Johansson, K. E. and Fellström, C. (2007): A novel enteropathogenic, strongly haemolytic spirochaete isolated from pig and mallard, provisionally designated ‘Brachyspira suanatina' sp. nov. Environ. Microbiol. 9, 983991.

    • Search Google Scholar
    • Export Citation
  • Rohde, J., Habighorst-Blome, K. and Seehusen, F. (2014): Brachyspira hampsonii” clade I isolated from Belgian pigs imported to Germany. Vet. Microbiol. 168, 432435.

    • Search Google Scholar
    • Export Citation
  • Rohde, J., Majzoub-Altweck, M., Falkenau, A., Hermanns, W., Burrough, E. R., Ritzmann, M. and Stadler, J. (2018): Occurrence of dysentery-like diarrhoea associated with Brachyspira suanatina infection on a German fattening pig farm. Vet. Rec. 182, 195.

    • Search Google Scholar
    • Export Citation
  • Rubin, J. E., Costa, M. O., Hill, J. E., Kittrell, H. E., Fernando, C., Huang, Y., O'Connor, B. and Harding, J. C. (2013a): Reproduction of mucohaemorrhagic diarrhea and colitis indistinguishable from swine dysentery following experimental inoculation with “Brachyspira hampsonii” strain 30446. PLoS One 8, e57146.

    • Search Google Scholar
    • Export Citation
  • Rubin, J. E., Harms, N. J., Fernando, C., Soos, C., Detmer, S. E., Harding, J. C. and Hill, J. E. (2013b): Isolation and characterization of Brachyspira spp. including “Brachyspira hampsonii” from lesser snow geese (Chen caerulescens caerulescens) in the Canadian Arctic. Microb. Ecol. 66, 813822.

    • Search Google Scholar
    • Export Citation
  • Siba, P. M., Pethick, D. W. and Hampson, D. J. (1996): Pigs experimentally infected with Serpulina hyodysenteriae can be protected from developing swine dysentery by feeding them a highly digestible diet. Epidem. Infect. 116, 207216.

    • Search Google Scholar
    • Export Citation
  • Song, Y., La, T., Phillips, N. D., Bellgard, M. I. and Hampson, D. J. (2009): A reverse vaccinology approach to swine dysentery vaccine development. Vet. Microbiol. 137, 111119.

    • Search Google Scholar
    • Export Citation
  • Taylor, D. J. and Alexander, T. J. (1971): The production of dysentery in swine by feeding cultures containing a spirochaete. Br. Vet. J. 127, 5861.

    • Search Google Scholar
    • Export Citation
  • Taylor, D. J., Simmons, J. R. and Laird, H. M. (1980): Production of diarrhoea and dysentery in pigs by feeding pure cultures of a spirochaete differing from Treponema hyodysenteriae. Vet. Rec. 106, 326332.

    • Search Google Scholar
    • Export Citation
  • Waters, W. R., Sacco, R. E., Dorn, A. D., Hontecillas, R., Zuckermann, F. A. and Wannemuehler, M. J. (1999): Systemic and mucosal immune responses of pigs to parenteral immunization with a pepsin-digested Serpulina hyodysenteriae bacterin. Vet. Immunol. Immunopathol. 69, 7587.

    • Search Google Scholar
    • Export Citation
  • Wilberts, B. L., Arruda, P. H., Warneke, H. L., Erlandson, K. R., Hammer, J. M. and Burrough, E. R. (2014): Cessation of clinical disease and spirochete shedding after tiamulin treatment in pigs experimentally infected with “Brachyspira hampsonii . Res. Vet. Sci. 97, 341347.

    • Search Google Scholar
    • Export Citation
  • Żmudzki, J., Szczotka, A., Nowak, A., Strzelecka, H., Grzesiak, A. and Pejsak, Z. (2012): Antimicrobial susceptibility of Brachyspira hyodysenteriae isolated from 21 Polish farms. Pol. J. Vet. Sci. 15, 259265.

    • Search Google Scholar
    • Export Citation
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Editor-in-Chief: Ferenc BASKA

Editorial assistant: Szilvia PÁLINKÁS

 

Editorial Board

  • Mária BENKŐ (Acta Veterinaria Hungarica, Budapest, Hungary)
  • Gábor BODÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Béla DÉNES (University of Veterinary Medicine, Budapest Hungary)
  • Edit ESZTERBAUER (Veterinary Medical Research Institute, Budapest, Hungary)
  • Hedvig FÉBEL (National Agricultural Innovation Centre, Herceghalom, Hungary)
  • László FODOR (University of Veterinary Medicine, Budapest, Hungary)
  • János GÁL (University of Veterinary Medicine, Budapest, Hungary)
  • Balázs HARRACH (Veterinary Medical Research Institute, Budapest, Hungary)
  • Peter MASSÁNYI (Slovak University of Agriculture in Nitra, Nitra, Slovak Republic)
  • Béla NAGY (Veterinary Medical Research Institute, Budapest, Hungary)
  • Tibor NÉMETH (University of Veterinary Medicine, Budapest, Hungary)
  • Zsuzsanna NEOGRÁDY (University of Veterinary Medicine, Budapest, Hungary)
  • Dušan PALIĆ (Ludwig Maximilian University, Munich, Germany)
  • Alessandra PELAGALLI (University of Naples Federico II, Naples, Italy)
  • Kurt PFISTER (Ludwig-Maximilians-University of Munich, Munich, Germany)
  • László SOLTI (University of Veterinary Medicine, Budapest, Hungary)
  • József SZABÓ (University of Veterinary Medicine, Budapest, Hungary)
  • Péter VAJDOVICH (University of Veterinary Medicine, Budapest, Hungary)
  • János VARGA (University of Veterinary Medicine, Budapest, Hungary)
  • Štefan VILČEK (University of Veterinary Medicine in Kosice, Kosice, Slovak Republic)
  • Károly VÖRÖS (University of Veterinary Medicine, Budapest, Hungary)
  • Herbert WEISSENBÖCK (University of Veterinary Medicine, Vienna, Austria)
  • Attila ZSARNOVSZKY (Szent István University, Gödöllő, Hungary)

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Acta Veterinaria Hungarica
Language English
Size A4
Year of
Foundation
1951
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per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
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