Authors:
Kinga Hadzsiev Department of Medical Genetics and Child Development Pécs, Hungary

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A. Tárnok Department of Paediatrics, University of Pécs Pécs, Hungary

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G. Kosztolányi Department of Medical Genetics and Child Development Research Group of Clinical Genetics of the Hungarian Academy of Sciences at the University of Pécs Pécs, Hungary

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K. Méhes Research Group of Clinical Genetics of the Hungarian Academy of Sciences at the University of Pécs Pécs, Hungary

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In a prospective study, the occurrence of malignancies in children referred to genetic counseling for congenital malformations, in their sibs, parents and grandparents was registered in 120 families by means of personal interviews. One hundred-and-twenty age matched subjects, admitted for acute respiratory infections or trauma, served as controls. No difference in the occurrence of tumors or leukemias between the two groups was found when the values of patients, sibs, and parents were compared. At the same time, the grandparents of probands with malformations had had significantly more malignancies than the grandparents of the controls. This may be explained by the fact that grandparents lived beyond the age of the usual onset of common cancers and leukemias.

  • Méhes, K., Weisenbach, J., Kajtár, P. (2003) Association of Wilms tumor with spinal dysraphism. Pediatr. Hematol. Oncol. 20, 261-264.

    'Association of Wilms tumor with spinal dysraphism ' () 20 Pediatr. Hematol. Oncol. : 261 -264 .

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  • Méhes K., Kosztolányi G. (2004) Clinical manifestations of genetic instability overlap one another. Pathol. Oncol. Res. 10, 12-16.

    'Clinical manifestations of genetic instability overlap one another ' () 10 Pathol. Oncol. Res. : 12 -16 .

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  • Merks, J. H. M., Caron, H. N., Hennekam, R. C. (2005) High incidence of malformation syndromes in a series of 1,073 children with cancer. Am. J. Med. Genet.134A, 132-143.

    'High incidence of malformation syndromes in a series of 1,073 children with cancer ' () 134A Am. J. Med. Genet. : 132 -143 .

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  • Stoll, C., Feingold, J. (2004) Do parents and grandparents of patients with achondroplasia have a higher cancer risk? Am. J. Med. Genet.130A, 165-168.

    'Do parents and grandparents of patients with achondroplasia have a higher cancer risk? ' () 130A Am. J. Med. Genet. : 165 -168 .

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  • Zhu, J. L., Basso, O., Hasle, H., Winther, J. F., Olsen, J. H., Olsen, J. (2002) Do parents of children with congenital malformations have a higher cancer risk? A nationwide study in Denmark. Br. J. Cancer 87, 524-528.

    'Do parents of children with congenital malformations have a higher cancer risk? A nationwide study in Denmark ' () 87 Br. J. Cancer : 524 -528 .

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  • Gundy, S., Babosa, M., Baki, M., Bodrogi, I. (2004) Increased predisposition to cancer in brothers and offspring of testicular tumor patients. Pathol. Oncol. Res. 10, 197-203.

    'Increased predisposition to cancer in brothers and offspring of testicular tumor patients ' () 10 Pathol. Oncol. Res. : 197 -203 .

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  • Hemminki, K., Eng, C. (2004) Clinical genetic counselling for familial cancers requires reliable data on familial cancer risks and general action plans. J. Med. Genet. 41, 801-807.

    'Clinical genetic counselling for familial cancers requires reliable data on familial cancer risks and general action plans ' () 41 J. Med. Genet. : 801 -807 .

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  • Méhes, K., Kajtár, P., Sándor, G., Scheel-Walter, M., Niethammer, D. (1998) Excess of mild errors of morphogenesis in childhood lymphoblastic leukemia. Am. J. Med. Genet. 75, 22-27.

    'Excess of mild errors of morphogenesis in childhood lymphoblastic leukemia ' () 75 Am. J. Med. Genet. : 22 -27 .

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  • Agha, M. M., Williams, J. I., Marrett, L., To, T., Zipursky, A., Dodds, L. (2005) Congenital abnormalities and childhood cancer. Cancer 103, 1939-1945.

    'Congenital abnormalities and childhood cancer ' () 103 Cancer : 1939 -1945 .

  • Friedman, J. M. (1997) Genetics and epidemiology, congenital anomalies and cancer (invited editorial). Am. J. Hum. Genet. 60, 469-473.

    'Genetics and epidemiology, congenital anomalies and cancer (invited editorial) ' () 60 Am. J. Hum. Genet. : 469 -473 .

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Editorial Board

    1. Csányi, Vilmos (Göd)
    1. Dudits, Dénes (Szeged)
    1. Falus, András (Budapest)
    1. Fischer, Ernő (Pécs)
    1. Gábriel, Róbert (Pécs)
    1. Gulya, Károly (Szeged)
    1. Gulyás, Balázs (Stockholm)
    1. Hajós, Ferenc (Budapest)
    1. Hámori, József (Budapest)
    1. Heszky, László (Gödöllő)
    1. Hideg, Éva (Szeged)
    1. E. Ito (Sanuki)
    1. Janda, Tibor (Martonvásár)
    1. Kavanaugh, Michael P. (Missoula)
    1. Kása, Péter (Szeged)
    1. Klein, Éva (Stockholm)
    1. Kovács, János (Budapest)
    1. Brigitte Mauch-Mani (Neuchâtel)
    1. Nässel, Dick R. (Stockholm)
    1. Nemcsók, János (Szeged)
    1. Péczely, Péter (Gödöllő)
    1. Roberts, D. F. (Newcastle-upon-Tyne)
    1. Sakharov, Dimitri A. (Moscow)
    1. Singh, Meharvan (Fort Worth)
    1. Sipiczky, Mátyás (Debrecen)
    1. Szeberényi, József (Pécs)
    1. Székely, György (Debrecen)
    1. Tari, Irma (Szeged)
    1. Vágvölgyi, Csaba (Szeged),
    1. L. Zaborszky (Newark)

 

Acta Biologica Hungarica
P.O. Box 35
H-8237 Tihany, Hungary
Phone: (36 87) 448 244 ext. 103
Fax: (36 87) 448 006
E-mail: elekes@tres.blki.hu

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Acta Biologica Hungarica
Language English
Size  
Year of
Foundation
1950
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5383 (Print)
ISSN 1588-256X (Online)