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L. M. Jesus Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes Av. 28 de Setembro, 87, 5° andar, Vila Isabel, Rio de Janeiro, Brasil

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P. R. C. Abreu Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes Av. 28 de Setembro, 87, 5° andar, Vila Isabel, Rio de Janeiro, Brasil

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Marcela C. Almeida Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes Av. 28 de Setembro, 87, 5° andar, Vila Isabel, Rio de Janeiro, Brasil

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Lavínia C. Brito Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes Av. 28 de Setembro, 87, 5° andar, Vila Isabel, Rio de Janeiro, Brasil

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Sheila F. Soares Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes Av. 28 de Setembro, 87, 5° andar, Vila Isabel, Rio de Janeiro, Brasil

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D. E. De Souza Departamento de Farmacologia e Psicobiologia, Instituto de Biologia Roberto Alcantara Gomes Av. 28 de Setembro, 87, 5° andar, Vila Isabel, Rio de Janeiro, Brasil

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Luciana C. Bernardo Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes Av. 28 de Setembro, 87, 5° andar, Vila Isabel, Rio de Janeiro, Brasil

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A. S. Fonseca Departamento de Farmacologia e Psicobiologia, Instituto de Biologia Roberto Alcantara Gomes Av. 28 de Setembro, 87, 5° andar, Vila Isabel, Rio de Janeiro, Brasil

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M. Bernardo-Filho Departamento de Biofísica e Biometria, Instituto de Biologia Roberto Alcantara Gomes Av. 28 de Setembro, 87, 5° andar, Vila Isabel, Rio de Janeiro, Brasil

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Since ancient times propolis has been employed for many human purposes because to their favourable properties. Blood constituents labeled with technetium-99m (99mTc) have been used in nuclear medicine procedures. Some authors have reported that synthetic or natural drugs can interfere with the labeling of blood constituents with 99mTc. The aim of this work was to evaluate the action of a propolis extract on the labeling of blood elements with 99mTc. Samples of whole blood of male Wistar rats were incubated in sequence with an aqueous propolis extract at different concentrations, stannous chloride and 99mTc, as sodium pertechnetate. Blood samples were centrifuged to separate plasma and blood cells, soluble and insoluble fractions of plasma and blood cells were also separated after precipitation in trichloroacetic acid solution and centrifugation. The radioactivity was counted and the percentage of incorporated radioactivity (%ATI) for each fraction was calculated. The data obtained showed that the aqueous propolis extract used decreased significantly the %ATI in plasma proteins at higher concentration studied. Results suggest that at high concentration the constituents of this extract could alter the labeling of plasma proteins competing with same binding sites of the 99mTc on the plasma proteins or acting as antioxidant compounds.

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Editorial Board

    1. Csányi, Vilmos (Göd)
    1. Dudits, Dénes (Szeged)
    1. Falus, András (Budapest)
    1. Fischer, Ernő (Pécs)
    1. Gábriel, Róbert (Pécs)
    1. Gulya, Károly (Szeged)
    1. Gulyás, Balázs (Stockholm)
    1. Hajós, Ferenc (Budapest)
    1. Hámori, József (Budapest)
    1. Heszky, László (Gödöllő)
    1. Hideg, Éva (Szeged)
    1. E. Ito (Sanuki)
    1. Janda, Tibor (Martonvásár)
    1. Kavanaugh, Michael P. (Missoula)
    1. Kása, Péter (Szeged)
    1. Klein, Éva (Stockholm)
    1. Kovács, János (Budapest)
    1. Brigitte Mauch-Mani (Neuchâtel)
    1. Nässel, Dick R. (Stockholm)
    1. Nemcsók, János (Szeged)
    1. Péczely, Péter (Gödöllő)
    1. Roberts, D. F. (Newcastle-upon-Tyne)
    1. Sakharov, Dimitri A. (Moscow)
    1. Singh, Meharvan (Fort Worth)
    1. Sipiczky, Mátyás (Debrecen)
    1. Szeberényi, József (Pécs)
    1. Székely, György (Debrecen)
    1. Tari, Irma (Szeged)
    1. Vágvölgyi, Csaba (Szeged),
    1. L. Zaborszky (Newark)

 

Acta Biologica Hungarica
P.O. Box 35
H-8237 Tihany, Hungary
Phone: (36 87) 448 244 ext. 103
Fax: (36 87) 448 006
E-mail: elekes@tres.blki.hu

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Acta Biologica Hungarica
Language English
Size  
Year of
Foundation
1950
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5383 (Print)
ISSN 1588-256X (Online)