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  • 1 Russian Academy of Sciences Institute for Developmental Biology Vavilov str. 26 119991 Moscow Russia
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NO-generating drugs (SNP, SNAP, NaNO 2 ) activated the standard buccal rhythm and simultaneously slowed down the endogenous rhythm of the NO-synthesizing neuron B2 which enhances gut motility. In the B2, these drugs caused giant hyperpolarizing waves strongly associated with the buccal cycles. Hyperpolarizing waves on the B2 could also be induced by prolonged stimulation of the B2. The inhibitor of NO-synthase L-NNA or the NO scavanger PTIO abolished giant hyperpolarizing waves, depolarised the B2 and activated fast bursting in the B2. The results suggest that NO may be involved in coordination of radula and foregut movements.

  • Benjamin, P. R., Rose, R. M. (1979) Central generation of bursting in the feeding system of the snail, Lymnaea stagnalis. J. Exp. Biol. 80 , 93–118.

    Rose R. M. , 'Central generation of bursting in the feeding system of the snail, Lymnaea stagnalis ' (1979 ) 80 J. Exp. Biol. : 93 -118.

    • Search Google Scholar
  • Dyakonova, T. L., Dyakonova, V. E. (2007) Function of glutamate in a pattern-generating network is modified by nitric oxide. Russ. J. Physiol. 93 , 236–247 [in Russian].

    Dyakonova V. E. , 'Function of glutamate in a pattern-generating network is modified by nitric oxide ' (2007 ) 93 Russ. J. Physiol. : 236 -247.

    • Search Google Scholar
  • Elliott, C. J., Susswein, A. J. (2002) Comparative neuroethology of feeding control in molluscs. Review. J. Exp. Biol. 205 , 877–896.

    Susswein A. J. , 'Comparative neuroethology of feeding control in molluscs ' (2002 ) 205 Review. J. Exp. Biol. : 877 -896.

    • Search Google Scholar
  • Elphick, M. R., Kemenes, G., Staras, K., O’shea, M. (1995) Behavioral role for nitric oxide in chemosensory activation of feeding in a mollusc. J. Neurosci. 15 , 7653–7664.

    O’shea M. , 'Behavioral role for nitric oxide in chemosensory activation of feeding in a mollusc ' (1995 ) 15 J. Neurosci. : 7653 -7664.

    • Search Google Scholar
  • Ji-Ho Park, Straub, V. A., O’shea, M. (1998) Anterograde signaling by nitric oxide: characterization and in vitro reconstitution of an identified nitrergic synapse. J. Neurosci. 18 , 5463–5476.

    O’shea M. , 'Anterograde signaling by nitric oxide: characterization and in vitro reconstitution of an identified nitrergic synapse ' (1998 ) 18 J. Neurosci. : 5463 -5476.

    • Search Google Scholar
  • Moroz, L. L., Ji-Ho Park, Winlow, W. (1993) Nitric oxide activates buccal motor patterns in Lymnaea stagnalis. NeuroReport 4 , 643–646.

    Winlow W. , 'Nitric oxide activates buccal motor patterns in Lymnaea stagnalis ' (1993 ) 4 NeuroReport : 643 -646.

    • Search Google Scholar
  • Moroz, L. L., Dahlgren, R. L., Boudko, D., Sweedler, J. V., Lovell, P. (2005) Direct single cell determination of nitric oxide synthase related metabolites in identified nitrergic neurons. J. Inorg. Biochem. 99 , 929–939.

    Lovell P. , 'Direct single cell determination of nitric oxide synthase related metabolites in identified nitrergic neurons ' (2005 ) 99 J. Inorg. Biochem. : 929 -939.

    • Search Google Scholar
  • Perry, S. J., Straub, V. A., Kemenes, G., Santama, N., Worster, B. M., Burke, J. F., Benjamin, P. R. (1998) Neural modulation of gut motility by myomodulin peptides and acetylcholine in the snail Lymnaea. J. Neurophysiol. 79 , 2460–2474.

    Benjamin P. R. , 'Neural modulation of gut motility by myomodulin peptides and acetylcholine in the snail Lymnaea ' (1998 ) 79 J. Neurophysiol. : 2460 -2474.

    • Search Google Scholar
  • Sadamoto, H., Hatakeyama, D., Kojima, S., Fujito, S., Ito, E. (1998) Histochemical study on the relation between NO-generative neurons and central circuitry for feeding in the pond snail, Lymnaea stagnalis. Neurosci. Res. 32 , 57–63.

    Ito E. , 'Histochemical study on the relation between NO-generative neurons and central circuitry for feeding in the pond snail, Lymnaea stagnalis ' (1998 ) 32 Neurosci. Res. : 57 -63.

    • Search Google Scholar