Acta Biologica Hungarica
Volume/Issue:
Volume 60: Issue 4
Distribution of oxytocin-immunoreactive neuronal elements in the rat spinal cord
Authors:
Julianna Jójárt University of Szeged Department of Anatomy Szeged Hungary

Search for other papers by Julianna Jójárt in
Current site
Google Scholar
PubMed Close
,
I. Jójárt Erzsébet Hospital Department of Medicine Hódmezővásárhely Hungary

Search for other papers by I. Jójárt in
Current site
Google Scholar
PubMed Close
,
Krisztina Boda University of Szeged Department of Medical Informatics Szeged Hungary

Search for other papers by Krisztina Boda in
Current site
Google Scholar
PubMed Close
,
Márta Gálfi University of Szeged Gyula Juhász Faculty of Education, Institute of Applied Natural Science Szeged Hungary

Search for other papers by Márta Gálfi in
Current site
Google Scholar
PubMed Close
,
A. Mihály University of Szeged Department of Anatomy Szeged Hungary

Search for other papers by A. Mihály in
Current site
Google Scholar
PubMed Close
,
Zs. B.-Baldauf University of Szeged Department of Anatomy Szeged Hungary

Search for other papers by Zs. B.-Baldauf in
Current site
Google Scholar
PubMed Close
, and
M. Vecsernyés University of Debrecen Pharmaceutical Technology Department Debrecen Hungary

Search for other papers by M. Vecsernyés in
Current site
Google Scholar
PubMed Close
Pages:
333–346
Online Publication Date:
16 Dec 2009
Publication Date:
01 Dec 2009
Article Category:
Research Article
DOI:
https://doi.org/10.1556/abiol.60.2009.4.1
Keywords:
Oxytocin; distribution; immunocytochemistry; radioimmunoassay; spinal cord
Restricted access

We investigated the distribution of oxytocin in rat spinal cord using immunocytochemistry and radioimmunoassay (RIA). Each segment of the spinal cord from cervical to coccygeal contained oxytocin-immunoreactive fibers. The Rexed laminae I and II of the dorsal horn showed moderate to intense immunoreactivity. A dense network was found around the central canal where some fibers apposed the ependyma. The autonomic centers of the spinal cord at the thoracolumbar and sacral segments were heavily innervated. Few fibers were found around the motoneurons. In the white matter, the immunoreactivity was localized mainly in the dorsal part of the lateral funiculus, in the pars funicularis of the nucleus intermediolateralis and in a longitudinal network of the lateral funiculus below the spinal cord surface. Some fibers from this network entered the pia mater. RIA measurements revealed that the cervical spinal cord had lower oxytocin content than that found in either the thoracic, lumbar, sacral or coccygeal region. Our results show that the distribution of oxytocin-immunoreactive fibers in the spinal cord correlates with anatomic locations related to nociceptive, autonomic and motor functions. We assume that oxytocin-containing axons play a role in secreting oxytocin directly into the liquor space of the spinal cord.

  • Argiolas, A., Melis, M. R. (2004) The role of oxytocin and the paraventricular nucleus in the sexual behaviour of male mammals. Physiol. Behav. 83 , 309–317.

    Melis M. R. , 'The role of oxytocin and the paraventricular nucleus in the sexual behaviour of male mammals ' (2004 ) 83 Physiol. Behav. : 309 -317 .

    • Search Google Scholar

  • Arletti, R., Benelli, A., Bertolini, A. (1993) Influence of oxytocin on nociception and morphine antinociception. Neuropeptides 24 , 125–129.

    Bertolini A. , 'Influence of oxytocin on nociception and morphine antinociception ' (1993 ) 24 Neuropeptides : 125 -129 .

    • Search Google Scholar

  • Benoussaidh, A., Maurin, Y., Rampin, O. (2004) Spinal effects of oxytocin on uterine motility in anesthetized rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 287 , R446–R453.

    Rampin O. , 'Spinal effects of oxytocin on uterine motility in anesthetized rats ' (2004 ) 287 Am. J. Physiol. Regul. Integr. Comp. Physiol. : R446 -R453 .

    • Search Google Scholar

  • Buijs, R. M. (1978) Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat. Pathways to the limbic system, medulla oblongata and spinal cord. Cell Tiss. Res. 192 , 423–435.

    Buijs R. M. , 'Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat. Pathways to the limbic system, medulla oblongata and spinal cord ' (1978 ) 192 Cell Tiss. Res. : 423 -435 .

    • Search Google Scholar

  • Buijs, R. M. (1980) Vasopressin and Oxytocin Innervation of the Rat Brain. A Light- and Electronmicroscopical Study. PhD Thesis, Amsterdam.

  • Buijs, R. M. (1983) Vasopressin and oxytocin — their role in neurotransmission. Pharmac. Ther. 22 , 127–141.

    Buijs R. M. , 'Vasopressin and oxytocin — their role in neurotransmission ' (1983 ) 22 Pharmac. Ther. : 127 -141 .

    • Search Google Scholar

  • Condés-Lara, M., González, N. M., Martínez-Lorenzana, G., Delgado, O. L., Freund-Mercier, M. J. (2003) Actions of oxytocin and interactions with glutamate on spontaneous and evoked dorsal spinal cord neuronal activities. Brain Res. 976 , 75–81.

    Freund-Mercier M. J. , 'Actions of oxytocin and interactions with glutamate on spontaneous and evoked dorsal spinal cord neuronal activities ' (2003 ) 976 Brain Res. : 75 -81 .

    • Search Google Scholar

  • Daddona, M. M., Haldar, J. (1994) Opioid modulation of oxytocin release from spinal cord synaptosomes. Neuroreport 5 , 1833–1835.

    Haldar J. , 'Opioid modulation of oxytocin release from spinal cord synaptosomes ' (1994 ) 5 Neuroreport : 1833 -1835 .

    • Search Google Scholar

  • Dogterom, J., Van Wimersma Greidanus, T. B., Swaab, D. F. (1977) Evidence for the release of vasopressin and oxytocin into cerebrospinal fluid: measurements in plasma and CSF of intact and hypophysectomized rats. Neuroendocrinology 24 , 108–118.

    Swaab D. F. , 'Evidence for the release of vasopressin and oxytocin into cerebrospinal fluid: measurements in plasma and CSF of intact and hypophysectomized rats ' (1977 ) 24 Neuroendocrinology : 108 -118 .

    • Search Google Scholar

  • Gibson, S. J., Polak, J. M., Bloom, S. R., Wall, P. D. (1981) The distribution of nine peptides in rat spinal cord with special emphasis on the substantia gelatinosa and on the area around the central canal (lamina X). J. Comp. Neurol. 201 , 65–79.

    Wall P. D. , 'The distribution of nine peptides in rat spinal cord with special emphasis on the substantia gelatinosa and on the area around the central canal (lamina X) ' (1981 ) 201 J. Comp. Neurol. : 65 -79 .

    • Search Google Scholar

  • Gilbey, M. P., Coote, J. H., Fleetwood-Walker, S., Peterson, D. F. (1982) The influence of the paraventriculo-spinal pathway, and oxytocin and vasopressin on sympathetic preganglionic neurones. Brain Res. 251 , 283–290.

    Peterson D. F. , 'The influence of the paraventriculo-spinal pathway, and oxytocin and vasopressin on sympathetic preganglionic neurones ' (1982 ) 251 Brain Res. : 283 -290 .

    • Search Google Scholar

  • Hallbeck, M., Larhammar, D., Blomqvist, A. (2001) Neuropeptide expression in rat paraventricular hypothalamic neurons that project to the spinal cord. J. Comp. Neurol. 433 , 222–238.

    Blomqvist A. , 'Neuropeptide expression in rat paraventricular hypothalamic neurons that project to the spinal cord ' (2001 ) 433 J. Comp. Neurol. : 222 -238 .

    • Search Google Scholar

  • Hawthorn, J., Ang, V. T. Y., Jenkins, J. S. (1985) Effect of lesions in the hypothalamic paraventricular, supraoptic and suprachiasmatic nuclei on vasopressin and oxytocin in rat brain and spinal cord. Brain Res. 346 , 51–57.

    Jenkins J. S. , 'Effect of lesions in the hypothalamic paraventricular, supraoptic and suprachiasmatic nuclei on vasopressin and oxytocin in rat brain and spinal cord ' (1985 ) 346 Brain Res. : 51 -57 .

    • Search Google Scholar

  • Hosoya, Y., Matsukawa, M., Okado, N., Sugiura, Y., Kohno, K. (1995) Oxytocinergic innervation to the upper thoracic sympathetic preganglionic neurons in the rat. A light and electron microscopical study using a combined retrograde transport and immunocytochemical technique. Exp. Brain Res. 107 , 9–16.

    Kohno K. , 'Oxytocinergic innervation to the upper thoracic sympathetic preganglionic neurons in the rat. A light and electron microscopical study using a combined retrograde transport and immunocytochemical technique ' (1995 ) 107 Exp. Brain Res. : 9 -16 .

    • Search Google Scholar

  • Jenkins, J. S., Ang, V. T., Hawthorn, J., Rossor, M. N., Iversen, L. L. (1984) Vasopressin, oxytocin and neurophysins in the human brain and spinal cord. Brain Res. 291 , 111–117.

    Iversen L. L. , 'Vasopressin, oxytocin and neurophysins in the human brain and spinal cord ' (1984 ) 291 Brain Res. : 111 -117 .

    • Search Google Scholar

  • Jójárt, I., Vecsernyés, M., Jójárt, J., Laczi, F., Szabó, G., Kovács, G. L., Janáky, T., László, F. A., Telegdy, G. (1989) Acute effects of peripheral histamine administration on arginine-8-vasopressin and oxytocin levels in rat spinal cord. Endocrinologia Experimentalis 23 , 229–233.

    Telegdy G. , 'Acute effects of peripheral histamine administration on arginine-8-vasopressin and oxytocin levels in rat spinal cord ' (1989 ) 23 Endocrinologia Experimentalis : 229 -233 .

    • Search Google Scholar

  • Krukoff, T. L., Ciriello, J., Calaresu, F. R. (1985) Segmental distribution of peptide- and 5HT-like immunoreactivity in nerve terminals and fibers of the thoracolumbar sympathetic nuclei of the cat. J. Comp. Neurol. 240 , 103–116.

    Calaresu F. R. , 'Segmental distribution of peptide- and 5HT-like immunoreactivity in nerve terminals and fibers of the thoracolumbar sympathetic nuclei of the cat ' (1985 ) 240 J. Comp. Neurol. : 103 -116 .

    • Search Google Scholar

  • Lang, R. E., Heil, J., Ganten, D., Hermann, K., Rascher, W., Unger, T. (1983) Ef fect of lesions in the paraventricular nucleus of the hypothalamus on vasopressin and oxytocin contents in brainstem and spinal cord of rat. Brain Res. 260 , 326–329.

    Unger T. , 'Ef fect of lesions in the paraventricular nucleus of the hypothalamus on vasopressin and oxytocin contents in brainstem and spinal cord of rat ' (1983 ) 260 Brain Res. : 326 -329 .

    • Search Google Scholar

  • Loup, F., Tribollet, E., Dubois-Dauphin, M., Pizzolato, G., Dreifuss, J. J. (1989) Localization of oxytocin biding sites in the human brainstem and upper spinal cord: an autoradiographic study. Brain Res. 500 , 223–230.

    Dreifuss J. J. , 'Localization of oxytocin biding sites in the human brainstem and upper spinal cord: an autoradiographic study ' (1989 ) 500 Brain Res. : 223 -230 .

    • Search Google Scholar

  • Lowry, O. H., Rosebrough, N. J., Farr, A. L., Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193 , 265–275.

    Randall R. J. , 'Protein measurement with the Folin phenol reagent ' (1951 ) 193 J. Biol. Chem. : 265 -275 .

    • Search Google Scholar

  • Lukic, D., Haldar, J. (1993) Isotonic and hypertonic saline act as stressful stimuli for oxytocinergic system of the pituitary, hypothalamus and spinal cord. Life Sci. 53 , 579–584.

    Haldar J. , 'Isotonic and hypertonic saline act as stressful stimuli for oxytocinergic system of the pituitary, hypothalamus and spinal cord ' (1993 ) 53 Life Sci. : 579 -584 .

    • Search Google Scholar

  • Miaskowski, C., Ong, G. L., Haldar, J. (1987) Cyclic variations in spinal cord levels of oxytocin and vasopressin during the stages of the rat estrous cycle. Endocrinology 120 , 1685–1687.

    Haldar J. , 'Cyclic variations in spinal cord levels of oxytocin and vasopressin during the stages of the rat estrous cycle ' (1987 ) 120 Endocrinology : 1685 -1687 .

    • Search Google Scholar

  • Miaskowski, C., Ong, G. L., Lukic, D., Haldar, J. (1988) Immobilization stress affects oxytocin and vasopressin levels in hypothalamic and extrahypothalamic sites. Brain Res. 458 , 137–141.

    Haldar J. , 'Immobilization stress affects oxytocin and vasopressin levels in hypothalamic and extrahypothalamic sites ' (1988 ) 458 Brain Res. : 137 -141 .

    • Search Google Scholar

  • Nilaver, G., Zimmerman, E. A., Wilkins, J., Michaels, J., Hoffman, D., Silverman, A. J. (1980) Magnocellular hypothalamic projections to the lower brain stem and spinal cord of the rat. Immunocytochemical evidence for predominance of the oxytocin-neurophysin system compared to the vasopressin-neurophysin system. Neuroendocrinol. 30 , 150–158.

    Silverman A. J. , 'Magnocellular hypothalamic projections to the lower brain stem and spinal cord of the rat. Immunocytochemical evidence for predominance of the oxytocin-neurophysin system compared to the vasopressin-neurophysin system ' (1980 ) 30 Neuroendocrinol. : 150 -158 .

    • Search Google Scholar

  • Pandita, R. K., Nylén, A., Andersson, K.-E. (1998) Oxytocin-induced stimulation and inhibition of bladder activity in normal conscious rats — influence of nitric oxide synthase inhibition. Neuroscience 85 , 1113–1119.

    Andersson K.-E. , 'Oxytocin-induced stimulation and inhibition of bladder activity in normal conscious rats — influence of nitric oxide synthase inhibition ' (1998 ) 85 Neuroscience : 1113 -1119 .

    • Search Google Scholar

  • Petras, J. M., Cummings, J. F. (1972) Autonomic neurons in the spinal cord of the rhesus monkey: a correlation of the findings of cytoarchitectonics and sympathectomy with fiber degeneration following dorsal rhizotomy. J. Comp. Neurol. 146 , 189–218.

    Cummings J. F. , 'Autonomic neurons in the spinal cord of the rhesus monkey: a correlation of the findings of cytoarchitectonics and sympathectomy with fiber degeneration following dorsal rhizotomy ' (1972 ) 146 J. Comp. Neurol. : 189 -218 .

    • Search Google Scholar

  • Pittman, Q. J., Riphagen, C. L., Lederis, K. (1984) Release of immunoassayable neurohypophyseal peptides from rat spinal cord, in vivo . Brain Res. 300 , 321–326.

    Lederis K. , 'Release of immunoassayable neurohypophyseal peptides from rat spinal cord, in vivo ' (1984 ) 300 Brain Res. : 321 -326 .

    • Search Google Scholar

  • Raggenbass, M. (2001) Vasopressin- and oxytocin-induced activity in the central nervous system: electrophysiological studies using in-vitro systems. Prog. Neurobiol. 64 , 307–326.

    Raggenbass M. , 'Vasopressin- and oxytocin-induced activity in the central nervous system: electrophysiological studies using in-vitro systems ' (2001 ) 64 Prog. Neurobiol. : 307 -326 .

    • Search Google Scholar

  • Reiter, M. K., Kremarik, P., Freund-Mercier, M. J., Stoeckel, M. E., Desaulles, E., Feltz, P. (1994) Localization of oxytocin binding sites in the thoracic and upper lumbar spinal cord of the adult and postnatal rat: a histoautoradiographic study. Eur. J. Neurosci. 6 , 98–104.

    Feltz P. , 'Localization of oxytocin binding sites in the thoracic and upper lumbar spinal cord of the adult and postnatal rat: a histoautoradiographic study ' (1994 ) 6 Eur. J. Neurosci. : 98 -104 .

    • Search Google Scholar

  • Robinson, D. A., Wei, F., Wang, G. D., Li, P., Kim, S. J., Vogt, S. K., Muglia, L. J., Zhuo, M. (2002) Oxytocin mediates stress-induced analgesia in adult mice. J. Physiol. 540 , 593–606.

    Zhuo M. , 'Oxytocin mediates stress-induced analgesia in adult mice ' (2002 ) 540 J. Physiol. : 593 -606 .

    • Search Google Scholar

  • Rousselot, P., Papadopoulos, G., Merighi, A., Poulain, D. A., Theodosis, D. T. (1990) Oxytocinergic innervation of the rat spinal cord. An electron microscopic study. Brain Res. 529 , 178–184.

    Theodosis D. T. , 'Oxytocinergic innervation of the rat spinal cord. An electron microscopic study ' (1990 ) 529 Brain Res. : 178 -184 .

    • Search Google Scholar

  • Sansone, G. R., Gerdes, C. A., Steinman, J. L., Winslow, J. T., Ottenweller, J. E., Komisaruk, B. R., Insel, T. R. (2002) Vaginocervical stimulation releases oxytocin within the spinal cord in rats. Neuroendocrinology 75 , 306–315.

    Insel T. R. , 'Vaginocervical stimulation releases oxytocin within the spinal cord in rats ' (2002 ) 75 Neuroendocrinology : 306 -315 .

    • Search Google Scholar

  • Sansone, G. R., Komisaruk, B. R. (2001) Evidence that oxytocin is an endogenous stimulator of autonomic sympathetic preganglionics: the pupillary dilatation response to vaginocervical stimulation in the rat. Brain Res. 898 , 265–271.

    Komisaruk B. R. , 'Evidence that oxytocin is an endogenous stimulator of autonomic sympathetic preganglionics: the pupillary dilatation response to vaginocervical stimulation in the rat ' (2001 ) 898 Brain Res. : 265 -271 .

    • Search Google Scholar

  • Sawchenko, P. E., Swanson, L. W. (1982) Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat. J. Comp. Neurol. 205 , 260–272.

    Swanson L. W. , 'Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat ' (1982 ) 205 J. Comp. Neurol. : 260 -272 .

    • Search Google Scholar

  • Silverman, A.-J., Zimmerman, E. A. (1983) Magnocellular neurosecretory system. Ann. Rev. Neurosci. 6 , 357–380.

    Zimmerman E. A. , 'Magnocellular neurosecretory system ' (1983 ) 6 Ann. Rev. Neurosci. : 357 -380 .

    • Search Google Scholar

  • Sofroniew, M. V. (1980) Projections from vasopressin, oxytocin, and neurophysin neurons to neural targets in the rat and human. J. Histochem. Cytochem. 28 , 475–478.

    Sofroniew M. V. , 'Projections from vasopressin, oxytocin, and neurophysin neurons to neural targets in the rat and human ' (1980 ) 28 J. Histochem. Cytochem. : 475 -478 .

    • Search Google Scholar

  • Sofroniew, M. V. (1985) Vasopressin, oxytocin and their related neurophysins. In: Björklund, A., Hökfelt, T. (eds) Handbook of Chemical Neuroanatomy. Vol. 4: GABA and Neuropeptides in the CNS, Part I, Elsevier, Amsterdam, pp. 93–165.

    Sofroniew M. V. , '', in Handbook of Chemical Neuroanatomy. Vol. 4: GABA and Neuropeptides in the CNS, Part I , (1985 ) -.

  • Sofroniew, M. V., Weindl, A. (1978) Extrahypothalamic neurophysin-containing perikarya, fiber pathways and fiber clusters in the rat brain. Endocrinology 102 , 334–337.

    Weindl A. , 'Extrahypothalamic neurophysin-containing perikarya, fiber pathways and fiber clusters in the rat brain ' (1978 ) 102 Endocrinology : 334 -337 .

    • Search Google Scholar

  • Sofroniew, M. V., Weindl, A., Schrell U., Wetzstein, R. (1981) Immunohistochemistry of vasopressin, oxytocin and neurophysin in the hypothalamus and extrahypothalamic regions of the human and primate brain. Acta Histochem. Suppl. 24 , 79–95.

  • Sternberger, L. A., Hardy, P. H., Jr., Cuculis, J. J., Meyer, H. G. (1970) The unlabeled antibody enzyme method of immunohistochemistry. Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes. J. Histochem. Cytochem. 18 , 315–333.

    Meyer H. G. , 'The unlabeled antibody enzyme method of immunohistochemistry. Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes ' (1970 ) 18 J. Histochem. Cytochem. : 315 -333 .

    • Search Google Scholar

  • Swanson, L. W., McKellar, S. (1979) The distribution of oxytocin- and neurophysin-stained fibers in the spinal cord of the rat and monkey. J. Comp. Neurol. 188 , 87–106.

    McKellar S. , 'The distribution of oxytocin- and neurophysin-stained fibers in the spinal cord of the rat and monkey ' (1979 ) 188 J. Comp. Neurol. : 87 -106 .

    • Search Google Scholar

  • Tribollet, E., Barberis, C., Arsenijevic, Y. (1997) Distribution of vasopressin and oxytocin receptors in the rat spinal cord: sex-related differences and effect of castration in pudendal motor nuclei. Neuroscience 78 , 499–509.

    Arsenijevic Y. , 'Distribution of vasopressin and oxytocin receptors in the rat spinal cord: sex-related differences and effect of castration in pudendal motor nuclei ' (1997 ) 78 Neuroscience : 499 -509 .

    • Search Google Scholar

  • White, J. D., Krause, J. E., McKelvy, J. F. (1986) In vivo biosynthesis and transport of oxytocin, vasopressin and neurophysin from the hypothalamus to the spinal cord. Neuroscience 17 , 133–140.

    McKelvy J. F. , 'In vivo biosynthesis and transport of oxytocin, vasopressin and neurophysin from the hypothalamus to the spinal cord ' (1986 ) 17 Neuroscience : 133 -140 .

    • Search Google Scholar

  • Yang, J., Yang, Y., Chen J.-M., Liu, W.-Y., Wang, C.-H., Lin, B.-C. (2007) Central oxytocin enhances antinociception in the rat. Peptides 28 , 1113–1119.

    Lin B.-C. , 'Central oxytocin enhances antinociception in the rat ' (2007 ) 28 Peptides : 1113 -1119 .

    • Search Google Scholar

  • Yang, Z., Wheatley, M., Coote, J. H. (2002) Neuropeptides, amines and amino acids as mediators of the sympathetic effects of paraventricular nucleus activation in the rat. Exp. Physiol. 87 , 663–674.

    Coote J. H. , 'Neuropeptides, amines and amino acids as mediators of the sympathetic effects of paraventricular nucleus activation in the rat ' (2002 ) 87 Exp. Physiol. : 663 -674 .

    • Search Google Scholar

  • Yu, S.-Q., Lundeberg, T., Yu, L.-C. (2003) Involvement of oxytocin in spinal antinociception in rats with inflammation. Brain Res. 983 , 13–22.

    Yu L.-C. , 'Involvement of oxytocin in spinal antinociception in rats with inflammation ' (2003 ) 983 Brain Res. : 13 -22 .

    • Search Google Scholar
  • Collapse
  • Expand
Cover Acta Biologica Hungarica
Acta Biologica Hungarica
Print ISSN:
0236-5383
Online ISSN:
1588-256X

Senior editors

Editor(s)-in-Chief: Elekes, Károly

Editorial Board

    1. Csányi, Vilmos (Göd)
    1. Dudits, Dénes (Szeged)
    1. Falus, András (Budapest)
    1. Fischer, Ernő (Pécs)
    1. Gábriel, Róbert (Pécs)
    1. Gulya, Károly (Szeged)
    1. Gulyás, Balázs (Stockholm)
    1. Hajós, Ferenc (Budapest)
    1. Hámori, József (Budapest)
    1. Heszky, László (Gödöllő)
    1. Hideg, Éva (Szeged)
    1. E. Ito (Sanuki)
    1. Janda, Tibor (Martonvásár)
    1. Kavanaugh, Michael P. (Missoula)
    1. Kása, Péter (Szeged)
    1. Klein, Éva (Stockholm)
    1. Kovács, János (Budapest)
    1. Brigitte Mauch-Mani (Neuchâtel)
    1. Nässel, Dick R. (Stockholm)
    1. Nemcsók, János (Szeged)
    1. Péczely, Péter (Gödöllő)
    1. Roberts, D. F. (Newcastle-upon-Tyne)
    1. Sakharov, Dimitri A. (Moscow)
    1. Singh, Meharvan (Fort Worth)
    1. Sipiczky, Mátyás (Debrecen)
    1. Szeberényi, József (Pécs)
    1. Székely, György (Debrecen)
    1. Tari, Irma (Szeged)
    1. Vágvölgyi, Csaba (Szeged),
    1. L. Zaborszky (Newark)

 

Acta Biologica Hungarica
P.O. Box 35
H-8237 Tihany, Hungary
Phone: (36 87) 448 244 ext. 103
Fax: (36 87) 448 006
E-mail: elekes@tres.blki.hu

Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • Chemical Abstracts
  • Current Contents: Agriculture
  • Biology and Environmental Sciences
  • Elsevier BIOBASE
  • Global Health
  • Index Medicus
  • Index Veterinarius
  • Medline
  • Referativnyi Zhurnal
  • Science Citation Index
  • Science Citation Index Expanded (SciSearch)
  • SCOPUS
  • The ISI Alerting Services
  • Zoological Abstracts

 

Acta Biologica Hungarica
Language English
Size  
Year of
Foundation		 1950
Publication
Programme		 changed title
Volumes
per Year		  
Issues
per Year		  
Founder Magyar Tudományos Akadémia
Founder's
Address		 H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5383 (Print)
ISSN 1588-256X (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Jun 2024 8 0 0
Jul 2024 8 0 0
Aug 2024 30 1 0
Sep 2024 7 0 0
Oct 2024 63 0 0
Nov 2024 22 0 0
Dec 2024 0 0 0