Authors:
Márta M.-Hamvas University of Debrecen Department of Botany, Faculty of Science and Technology Egyetem tér 1 H-4010 Debrecen Hungary

Search for other papers by Márta M.-Hamvas in
Current site
Google Scholar
PubMed
Close
,
C. Máthé University of Debrecen Department of Botany, Faculty of Science and Technology Egyetem tér 1 H-4010 Debrecen Hungary

Search for other papers by C. Máthé in
Current site
Google Scholar
PubMed
Close
,
G. Vasas University of Debrecen Department of Botany, Faculty of Science and Technology Egyetem tér 1 H-4010 Debrecen Hungary

Search for other papers by G. Vasas in
Current site
Google Scholar
PubMed
Close
,
Katalin Jámbrik University of Debrecen Department of Botany, Faculty of Science and Technology Egyetem tér 1 H-4010 Debrecen Hungary

Search for other papers by Katalin Jámbrik in
Current site
Google Scholar
PubMed
Close
,
Mária Papp University of Debrecen Department of Botany, Faculty of Science and Technology Egyetem tér 1 H-4010 Debrecen Hungary

Search for other papers by Mária Papp in
Current site
Google Scholar
PubMed
Close
,
D. Beyer University of Debrecen Department of Botany, Faculty of Science and Technology Egyetem tér 1 H-4010 Debrecen Hungary

Search for other papers by D. Beyer in
Current site
Google Scholar
PubMed
Close
,
Ilona Mészáros University of Debrecen Department of Botany, Faculty of Science and Technology Egyetem tér 1 H-4010 Debrecen Hungary

Search for other papers by Ilona Mészáros in
Current site
Google Scholar
PubMed
Close
, and
G. Borbély University of Debrecen Department of Botany, Faculty of Science and Technology Egyetem tér 1 H-4010 Debrecen Hungary

Search for other papers by G. Borbély in
Current site
Google Scholar
PubMed
Close
Restricted access

This work focuses on the comparative analysis of the effects of two cyanobacterial toxins of different chemical structure cylindrospermopsin (CYN) and microcystin-LR (MC-LR) on the white mustard (Sinapis alba L.) seedlings. Both cyanotoxins reduced significantly the fresh mass and the length of cotyledons, hypocotyls and main roots of seedlings in a concentration dependent manner. For various mustard organs the 50% inhibitory concentration values (IC50) of growth were between 3–5 μg ml−1 for MC-LR and between 5–10 μg ml−1 for CYN, respectively. Cyanotoxins altered the development of cotyledons, the accumulation of photosynthetically active pigments and anthocyanins. Low MC-LR concentrations (0.01 and 0.1 μg ml−1) stimulated anthocyanin formation in the cotyledons but higher than 1 μg ml-1 MC-LR concentrations strongly inhibited it. The CYN treated chlorotic cotyledons were violet coloured in consequence of high level of anthocyanins, while MC-LR induced chlorosis was accompanied by the appearance of necrotic patches. Necrosis and increases of peroxidase enzyme activity (POD) are general stress responses but these alterations were characteristic only for MC-LR treated mustard plants. These findings provide experimental evidences of developmental alterations induced by protein synthesis and protein phosphatase inhibitory cyanotoxins (CYN and MC-LR) in a model dicotyledonous plant.

  • Abe, T., Lawson, T., Weyers, J. D. B., Codd, G. A. (1996) Microcystin-LR inhibits photosynthesis of Phaseolus vulgaris primary leaves: Implications for current spray irrigation practice. New Phytol. 133, 651–658.

    Codd G. A. , 'Microcystin-LR inhibits photosynthesis of Phaseolus vulgaris primary leaves: Implications for current spray irrigation practice ' (1996 ) 133 New Phytol. : 651 -658 .

    • Search Google Scholar
  • Abrahams, S., Tanner, G. J., Larkin, P. J., Ashton, A. (2002) Identification and biochemical characterization of mutants in the proanthocyanidin pathway in Arabidopsis. Plant Physiol. 130, 561–576.

    Ashton A. , 'Identification and biochemical characterization of mutants in the proanthocyanidin pathway in Arabidopsis ' (2002 ) 130 Plant Physiol. : 561 -576 .

    • Search Google Scholar
  • Allwood, E. G., Davies, D. R., Gerrish, C., Ellis, B. E., Bolwell, G. P. (1999) Phosphorylation of phenylalanine ammonia-lyase: evidence for a novel protein kinase and identification of the phosphorylated residue. FEBS Lett. 457, 47–52.

    Bolwell G. P. , 'Phosphorylation of phenylalanine ammonia-lyase: evidence for a novel protein kinase and identification of the phosphorylated residue ' (1999 ) 457 FEBS Lett. : 47 -52 .

    • Search Google Scholar
  • Armstrong, J., Armstrong, W. (2001) An overview of the effects of phytotoxins on Phragmites australis in relation to die-back. Aquatic Bot. 69, 251–268.

    Armstrong W. , 'An overview of the effects of phytotoxins on Phragmites australis in relation to die-back ' (2001 ) 69 Aquatic Bot. : 251 -268 .

    • Search Google Scholar
  • Arnon, D. I. (1949) Copper enzymes in chloroplasts: polyphenol oxidases in Beta vulgaris. Plant Physiol. 24, 1–15.

    Arnon D. I. , 'Copper enzymes in chloroplasts: polyphenol oxidases in Beta vulgaris ' (1949 ) 24 Plant Physiol. : 1 -15 .

    • Search Google Scholar
  • Banker, R., Carmeli, S., Hadas, O., Teltsch, B., Porat, R., Sukenik, A. (1997) Identification of cylindrospermopsin in Aphanizomenon ovalisporum (Cyanophyceae) isolated from lake Kinneret, Israel. J. Phycol. 33, 613–616.

    Sukenik A. , 'Identification of cylindrospermopsin in Aphanizomenon ovalisporum (Cyanophyceae) isolated from lake Kinneret, Israel ' (1997 ) 33 J. Phycol. : 613 -616 .

    • Search Google Scholar
  • Beyer, D., Surányi, G., Vasas, G., Roszik, J., Erdődi, F., M.-Hamvas, M., Bácsi, I., Bátori, R., Serfőző, Z., Szigeti, Z. M., Vereb, G., Demeter, Z., Gonda, S., Máthé, C. (2009) Cylindrospermopsin induces alterations of root histology and microtubule organization in common reed (Phragmites australis) plantlets cultured in vitro. Toxicon 54, 440–449.

    Máthé C. , 'Cylindrospermopsin induces alterations of root histology and microtubule organization in common reed (Phragmites australis) plantlets cultured in vitro ' (2009 ) 54 Toxicon : 440 -449 .

    • Search Google Scholar
  • Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding. Anal. Biochem. 72, 248–254.

    Bradford M. M. , 'A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principle of protein-dye binding ' (1976 ) 72 Anal. Biochem. : 248 -254 .

    • Search Google Scholar
  • Carmichael, W. W., Azevedo, S. M. F. O., An, J. S., Molica, R. J. R., Jochimsen, E. M., Lau, S., Rinehart, K. L., Shaw, G. R., Eaglesham, G. K. (2001) Human fatalities from cyanobacteria: chemical and biological evidence for cyanotoxins. Environ. Health Persp. 109, 663–668.

    Eaglesham G. K. , 'Human fatalities from cyanobacteria: chemical and biological evidence for cyanotoxins ' (2001 ) 109 Environ. Health Persp. : 663 -668 .

    • Search Google Scholar
  • Chalker-Scott, L. (1999) Environmental significance of anthocyanins in plant responses. Photochem. Photobiol. 70, 1–9.

    Chalker-Scott L. , 'Environmental significance of anthocyanins in plant responses ' (1999 ) 70 Photochem. Photobiol. : 1 -9 .

    • Search Google Scholar
  • Chen, J., Song, L., Dai, J., Gan, N., Liu, Z. (2004) Effects of microcystins on the growth and the activity of superoxide dismutase and peroxidase of rape (Brassica napus L.) and rice (Oryza sativa L.). Toxicon 43, 393–400.

    Liu Z. , 'Effects of microcystins on the growth and the activity of superoxide dismutase and peroxidase of rape (Brassica napus L.) and rice (Oryza sativa L.) ' (2004 ) 43 Toxicon : 393 -400 .

    • Search Google Scholar
  • Chong, M. W. K., Wong, B. S. F., Lam, P. K. S., Shaw, G. R., Seawright, A. A. (2002) Toxicity and uptake mechanism of cylindrospermopsin and lophyrotomin in primary rat hepatocytes. Toxicon 40, 205–211.

    Seawright A. A. , 'Toxicity and uptake mechanism of cylindrospermopsin and lophyrotomin in primary rat hepatocytes ' (2002 ) 40 Toxicon : 205 -211 .

    • Search Google Scholar
  • Codd, G. A., Metcalf, J. S., Beattie, K. A. (1999) Retention of Microcystis aeruginosa and microcystin by salad lettuce (Lactuca sativa) after spray irrigation with water containing cyanobacteria. Toxicon. 37, 1181–1185.

    Beattie K. A. , 'Retention of Microcystis aeruginosa and microcystin by salad lettuce (Lactuca sativa) after spray irrigation with water containing cyanobacteria ' (1999 ) 37 Toxicon. : 1181 -1185 .

    • Search Google Scholar
  • Cohen, P. (1989) The structure and regulation of protein phosphatases. Annu. Rev. Biochem. 58, 435–508.

    Cohen P. , 'The structure and regulation of protein phosphatases ' (1989 ) 58 Annu. Rev. Biochem. : 435 -508 .

    • Search Google Scholar
  • Dixon, R. A., Paiva, N. L. (1995) Stress induced phenylpropanoid metabolism. Plant Cell 7, 1085–1097.

    Paiva N. L. , 'Stress induced phenylpropanoid metabolism ' (1995 ) 7 Plant Cell : 1085 -1097 .

    • Search Google Scholar
  • Frosch, S., Bergfeld, R., Mohr, H. (1976) Light control of plastogenesis and ribulosebisphosphate carboxylase level in mustard seedling cotyledons. Planta 133, 53–56.

    Mohr H. , 'Light control of plastogenesis and ribulosebisphosphate carboxylase level in mustard seedling cotyledons ' (1976 ) 133 Planta : 53 -56 .

    • Search Google Scholar
  • Gácsi, M., Antal, O., Vasas, G., Máthé, Cs., Borbély, G., Saker, M. L., Győri, J., Farkas, A., Vehovszky, Á., Bánfalvy, G. (2009) Comparative study of cyanotoxins affecting cytoskeletal and chromatin structure in CHO-K1 cells. Toxicol. in Vitro 23, 710–718.

    Bánfalvy G. , 'Comparative study of cyanotoxins affecting cytoskeletal and chromatin structure in CHO-K1 cells ' (2009 ) 23 Toxicol. in Vitro : 710 -718 .

    • Search Google Scholar
  • Gehringer, M. M., Kewada, V., Coates, N., Downing, T. G. (2003) The use of Lepidium sativum in a plant bioassay system for the detection of microcystin-LR. Toxicon 41, 871–876.

    Downing T. G. , 'The use of Lepidium sativum in a plant bioassay system for the detection of microcystin-LR ' (2003 ) 41 Toxicon : 871 -876 .

    • Search Google Scholar
  • Glitz, D. C., Liu-Glitz, L., McClure, J. W., Huerta, A. J. (2004) Effects of a PAL inhibitor on phenolic accumulation and UV-B tolerance in Spirodela intermedia (Koch). J. Exp. Bot. 55, 919–927.

    Huerta A. J. , 'Effects of a PAL inhibitor on phenolic accumulation and UV-B tolerance in Spirodela intermedia (Koch) ' (2004 ) 55 J. Exp. Bot. : 919 -927 .

    • Search Google Scholar
  • Hale, K. L., McGrath, S. P., Lombi, E., Stack, S. M., Terry, N., Pickering, I. J., George, G. N., Pilon-Smith, E. A. H. (2001) Molybdenum sequestration in Brassica species. A role for anthocyanins? Plant Physiol. 126, 1391–1402.

    Pilon-Smith E. A. H. , 'Molybdenum sequestration in Brassica species. A role for anthocyanins? ' (2001 ) 126 Plant Physiol. : 1391 -1402 .

    • Search Google Scholar
  • Hodges, D. M., Nozzolillo, C. (1996) Anthocyanin and anthocyanoplast content of Cruciferous seedlings subjected to mineral nutrient deficiencies. J. Plant Physiol. 147, 749–754.

    Nozzolillo C. , 'Anthocyanin and anthocyanoplast content of Cruciferous seedlings subjected to mineral nutrient deficiencies ' (1996 ) 147 J. Plant Physiol. : 749 -754 .

    • Search Google Scholar
  • Holton, T. A., Cornish, E. C. (1995) Genetics and biochemistry of anthocyanin biosynthesis. Plant Cell 7, 1071–1083.

    Cornish E. C. , 'Genetics and biochemistry of anthocyanin biosynthesis ' (1995 ) 7 Plant Cell : 1071 -1083 .

    • Search Google Scholar
  • Huang, W., Xin, W., Li, D., Liu, Y. (2008) Microcystin-RR induced apoptosis in tobacco BY-2 suspension cells is mediated by reactive oxygen species and mitochondrial permeability transition pore status. Toxicol. in Vitro 22, 328–337.

    Liu Y. , 'Microcystin-RR induced apoptosis in tobacco BY-2 suspension cells is mediated by reactive oxygen species and mitochondrial permeability transition pore status ' (2008 ) 22 Toxicol. in Vitro : 328 -337 .

    • Search Google Scholar
  • Järvenpää, S., Lundberg-Niinistö, C., Spoof, L., Sjövall, O., Tyystjärvi, E., Meriluoto, J. (2007) Effects of microcystins on broccoli and mustard, and analysis of accumulated toxin by liquid chromatography-mass spectrometry. Toxicon 49(6), 865–874.

    Meriluoto J. , 'Effects of microcystins on broccoli and mustard, and analysis of accumulated toxin by liquid chromatography-mass spectrometry ' (2007 ) 49 Toxicon : 865 -874 .

    • Search Google Scholar
  • Kinnear, S. H. W., Fabbro, L. D., Duivenvoorden, L. J. (2008) Variable growth responses of water thyme (Hydrilla verticillata) to whole-cell extracts of Cylindrospermopsis raciborskii. Arch. Environ. Contam. Toxicol. 54, 187–194.

    Duivenvoorden L. J. , 'Variable growth responses of water thyme (Hydrilla verticillata) to whole-cell extracts of Cylindrospermopsis raciborskii ' (2008 ) 54 Arch. Environ. Contam. Toxicol. : 187 -194 .

    • Search Google Scholar
  • Kós, P., Gorzó, G., Surányi, G., Borbély, G. (1995) Simple and efficient method for isolation and measurement of cyanobacterial hepatotoxins by plant tests (Sinapis alba). Anal. Biochem. 225, 49–53.

    Borbély G. , 'Simple and efficient method for isolation and measurement of cyanobacterial hepatotoxins by plant tests (Sinapis alba) ' (1995 ) 225 Anal. Biochem. : 49 -53 .

    • Search Google Scholar
  • Kurki-Helasmo, K., Meriluoto, J. (1998) Microcystin uptake inhibits growth and protein phosphatase activity in mustard (Sinapis alba L.) seedlings. Toxicon 36, 1921–1926.

    Meriluoto J. , 'Microcystin uptake inhibits growth and protein phosphatase activity in mustard (Sinapis alba L.) seedlings ' (1998 ) 36 Toxicon : 1921 -1926 .

    • Search Google Scholar
  • Lange, H., Shropshire, W., Mohr, H. (1971) An analysis of phytochrome-mediated anthocyanin synthesis. Plant Physiol. 47, 649–655.

    Mohr H. , 'An analysis of phytochrome-mediated anthocyanin synthesis ' (1971 ) 47 Plant Physiol. : 649 -655 .

    • Search Google Scholar
  • Luan, S. (2003) Protein phosphatases in plants. Annu. Rev. Plant Biol. 54, 63–92.

    Luan S. , 'Protein phosphatases in plants ' (2003 ) 54 Annu. Rev. Plant Biol. : 63 -92 .

    • Search Google Scholar
  • MacKintosh, C., Beattie, K. A., Klumpp, S., Cohen, P., Codd, G. A. (1990) Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants. FEBS Lett. 264, 187–192.

    Codd G. A. , 'Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants ' (1990 ) 264 FEBS Lett. : 187 -192 .

    • Search Google Scholar
  • MacKintosh, C., Diplexcito, J. (2003) Naturally occurring inhibitors of serine/threonine phosphatases. In: Wells, J., Hunter, T., Karin, M., Farquhar, M., Thompson, B. (eds) Handbook of Cell Signaling. Vol. 1. Elsevier Science Publ., USA, pp. 607–611.

    Diplexcito J. , '', in Handbook of Cell Signaling. Vol. 1 , (2003 ) -.

  • Máthé, C., M.-Hamvas, M., Vasas, G., Surányi, G., Bácsi, I., Beyer, D., Tóth, S., TÍmár, M., Borbély, G. (2007) Microcystin-LR, a cyanobacterial toxin, induces growth inhibition and histological alterations in common reed (Phragmites australis) plants regenerated from embryonic calli. New Phytol. 176, 824–835.

    Borbély G. , 'Microcystin-LR, a cyanobacterial toxin, induces growth inhibition and histological alterations in common reed (Phragmites australis) plants regenerated from embryonic calli ' (2007 ) 176 New Phytol. : 824 -835 .

    • Search Google Scholar
  • McElhiney, J., Lawton, L. A., Leifert, C. (2001) Investigations into the inhibitory effects of microcystins on plant growth and the toxicity of plant tissues following exposure. Toxicon 39, 1411–1420.

    Leifert C. , 'Investigations into the inhibitory effects of microcystins on plant growth and the toxicity of plant tissues following exposure ' (2001 ) 39 Toxicon : 1411 -1420 .

    • Search Google Scholar
  • Metcalf, J. S., Barakate, A., Codd, G. A. (2004) Inhibition of plant protein synthesis by the cyanobacterial hepatotoxin, cylindrospermopsin. FEMS Microbiol. Lett. 235, 125–129.

    Codd G. A. , 'Inhibition of plant protein synthesis by the cyanobacterial hepatotoxin, cylindrospermopsin ' (2004 ) 235 FEMS Microbiol. Lett. : 125 -129 .

    • Search Google Scholar
  • Metcalf, J. S., Lindsay, J., Beattie, K. A., Birmingham, S., Saker, M. L., Törökné, A. K., Codd, G. A. (2002) Toxicity of cylindrospermopsin to the brine shrimp Artemia salina: comparisons with protein synthesis inhibitors and microcystins. Toxicon 40, 1115–1120.

    Codd G. A. , 'Toxicity of cylindrospermopsin to the brine shrimp Artemia salina: comparisons with protein synthesis inhibitors and microcystins ' (2002 ) 40 Toxicon : 1115 -1120 .

    • Search Google Scholar
  • M.-Hamvas, M., Veres, Sz., Mészáros, I., Máthé, Cs., Borbély, Gy. (2002) Mikrocisztin-LR hatása a mustár csÍranövények sziklevelének pigmentösszetételére és fotoszintetikus aktivitására. (Influence of microcystin-LR on the photosynthetic activity and pigment composition.) Hidrológiai Közlöny 82, 80–82. (In Hungarian with English abstract.)

    Borbély Gy. , 'Mikrocisztin-LR hatása a mustár csÍranövények sziklevelének pigmentösszetételére és fotoszintetikus aktivitására ' (2002 ) 82 Hidrológiai Közlöny : 80 -82 .

    • Search Google Scholar
  • M.-Hamvas, M., Máthé, Cs., Molnár, E., Vasas, G., Grigorszky, I., Borbely, G. (2003) Microcystin-LR alters the growth, anthocyanin content and single-stranded DNase enzyme activities in Sinapis alba L. seedlings. Aquat. Toxicol. 62, 1–9.

    Borbely G. , 'Microcystin-LR alters the growth, anthocyanin content and single-stranded DNase enzyme activities in Sinapis alba L. seedlings ' (2003 ) 62 Aquat. Toxicol. : 1 -9 .

    • Search Google Scholar
  • Mitrovic, S. M., Pflugmacher, S., James, K. J., Furey, A. (2004) Anatoxin-a elicits an increase in peroxidase and glutathione S-transferase activity in aquatic plants. Aquat. Toxicol. 68, 185–192.

    Furey A. , 'Anatoxin-a elicits an increase in peroxidase and glutathione S-transferase activity in aquatic plants ' (2004 ) 68 Aquat. Toxicol. : 185 -192 .

    • Search Google Scholar
  • Mohr, H. (1972) Lectures on Photomorphogenesis. Springer, Berlin, Heidelberg, New York.

    Mohr H. , '', in Lectures on Photomorphogenesis , (1972 ) -.

  • Mohr, H. (1982) Phytochrome and gene expression. In: Héléne, C., Charlier, M., Montenay-Garestier, Th., Laustriat, G. (eds) Trends in Photobiology. Plenum Press, New York, London, pp. 515–530.

    Mohr H. , '', in Trends in Photobiology , (1982 ) -.

  • Molnár, E., M.-Hamvas, M., Máthé, Cs., Vasas, G., Grigorszky, I., Borbély, Gy. (2000) Cianotoxinok hatása növényi peroxidázok aktivitására. (The alteration of peroxidase activity in cyanotoxin treated plants.) Hidrológiai Közlöny, 5–6, 871–872. (In Hungarian with English abstract.)

    Borbély Gy. , 'Cianotoxinok hatása növényi peroxidázok aktivitására ' (2000 ) 5–6 Hidrológiai Közlöny : 871 -872 .

    • Search Google Scholar
  • Navabpour, S., Morris, K., Allen, R., Harrison, E., A.-H.-Mackerness, S., Buchanan-Wollaston, V. (2003) Expression of senescence-enhanced genes in response to oxidative stress. J. Exp. Bot. 54, 2285–2292.

    Buchanan-Wollaston V. , 'Expression of senescence-enhanced genes in response to oxidative stress ' (2003 ) 54 J. Exp. Bot. : 2285 -2292 .

    • Search Google Scholar
  • Peuthert, A., Chakrabarti, S., Pflugmacher, S. (2007) Uptake of microcystin-LR and -LF (cyanobacterial toxins) in seedlings of several important agricultural plant species and the correlation with cellular damage (lipid peroxidation). Environ. Toxicol. 22, 436–442.

    Pflugmacher S. , 'Uptake of microcystin-LR and -LF (cyanobacterial toxins) in seedlings of several important agricultural plant species and the correlation with cellular damage (lipid peroxidation) ' (2007 ) 22 Environ. Toxicol. : 436 -442 .

    • Search Google Scholar
  • Pflugmacher, S., Codd, G. A., Steinberg, C. E. W. (1999) Effects of cyanobacterial toxin microcystin-LR on detoxication enzymes in aquatic plants. Environ. Toxicol. 14, 111–115.

    Steinberg C. E. W. , 'Effects of cyanobacterial toxin microcystin-LR on detoxication enzymes in aquatic plants ' (1999 ) 14 Environ. Toxicol. : 111 -115 .

    • Search Google Scholar
  • Pflugmacher, S. (2004) Promotion of oxidative stress in aquatic macrophyte Ceratophyllum demersum during biotransformation of the cyanobacterial toxin microcystin-LR. Aquat. Toxicol. 70, 169–178.

    Pflugmacher S. , 'Promotion of oxidative stress in aquatic macrophyte Ceratophyllum demersum during biotransformation of the cyanobacterial toxin microcystin-LR ' (2004 ) 70 Aquat. Toxicol. : 169 -178 .

    • Search Google Scholar
  • Pflugmacher, S., Aulhorn, M., Grimm, B. (2007) Influence of a cyanobacterial crude extract containing microcystin-LR on the physiology and antioxidative defence systems of different spinach variants. New Phytol. 175, 482–489.

    Grimm B. , 'Influence of a cyanobacterial crude extract containing microcystin-LR on the physiology and antioxidative defence systems of different spinach variants ' (2007 ) 175 New Phytol. : 482 -489 .

    • Search Google Scholar
  • Rakow, G., Raney, J. P., Relf-Eckstein, J., Rode, D. (2009) AC Pennant, AC Base and Andante yellow condiment mustard cultivars. Can. J. Plant Sci. 89, 331–336.

    Rode D. , 'AC Pennant, AC Base and Andante yellow condiment mustard cultivars ' (2009 ) 89 Can. J. Plant Sci. : 331 -336 .

    • Search Google Scholar
  • Rastogi, R. P., Sinha, R. P. (2009) Biotechnological and industrial significance of cyanobacterial secondary metabolites. Biotechnol. Adv. 27, 521–539.

    Sinha R. P. , 'Biotechnological and industrial significance of cyanobacterial secondary metabolites ' (2009 ) 27 Biotechnol. Adv. : 521 -539 .

    • Search Google Scholar
  • Reiss, T., Bergfeld, R., Link, G., Thien, W., Mohr, H. (1983) Photooxidative destruction of chloroplasts and its consequences for cytosolic enzyme levels and plant development. Planta 159, 518–528.

    Mohr H. , 'Photooxidative destruction of chloroplasts and its consequences for cytosolic enzyme levels and plant development ' (1983 ) 159 Planta : 518 -528 .

    • Search Google Scholar
  • Romanowska-Duda, Z., Mankiewicz, J., Tarczynska, M., Walter, Z., Zalewski, M. (2002) The effect of toxic cyanobacteria (Blue-Green Algae) on water plants and animal cells. Pol. J. Environ. Stud. 11, 561–566.

    Zalewski M. , 'The effect of toxic cyanobacteria (Blue-Green Algae) on water plants and animal cells ' (2002 ) 11 Pol. J. Environ. Stud. : 561 -566 .

    • Search Google Scholar
  • Ross, D. W., Brown, J., McCaffrey, J. P., Harmon, B. L., Davis, J. B. (2008) Cabbage seedpod weevil resistance in canola (Brassica napus L.), yellow mustard (Sinapis alba L.) and canola × yellow mustard hybrids. Can. J. Plant Sci. 88, 239–245.

    Davis J. B. , 'Cabbage seedpod weevil resistance in canola (Brassica napus L.), yellow mustard (Sinapis alba L.) and canola × yellow mustard hybrids ' (2008 ) 88 Can. J. Plant Sci. : 239 -245 .

    • Search Google Scholar
  • Saito, K., Yamazaki, M. (2002) Biochemistry and molecular biology of the late-stage of biosynthesis of anthocyanin: lessons from Perilla frutescens as a model plant. New Phytol. 155, 9–23.

    Yamazaki M. , 'Biochemistry and molecular biology of the late-stage of biosynthesis of anthocyanin: lessons from Perilla frutescens as a model plant ' (2002 ) 155 New Phytol. : 9 -23 .

    • Search Google Scholar
  • Saqrane, S., El Ghazali, I., Ouahid, Y., El Hassnib, M., El Hadrani, I., Bouarab, L., del Campo, F. F., Oudra, B., Vasconcelos, V. (2007) Phytotoxic effects of cyanobacteria extract on the aquatic plant Lemna gibba: microcystin accumulation, detoxication and oxidative stress induction. Aquat. Toxicol. 83, 284–294.

    Vasconcelos V. , 'Phytotoxic effects of cyanobacteria extract on the aquatic plant Lemna gibba: microcystin accumulation, detoxication and oxidative stress induction ' (2007 ) 83 Aquat. Toxicol. : 284 -294 .

    • Search Google Scholar
  • Smith, R. D., Walker, J. C. (1996) Plant protein phosphatases. Annu. Rev. Plant Phys. 47, 101–125.

    Walker J. C. , 'Plant protein phosphatases ' (1996 ) 47 Annu. Rev. Plant Phys. : 101 -125 .

    • Search Google Scholar
  • Spelt, C., Quattrocchio, F., Mol, J., Koes, R. (2002) ANTHOCYANIN 1 of Petunia controls pigment synthesis, vacuolar pH, and seed coat development by genetically distinct mechanisms. Plant Cell 14, 2121–2135.

    Koes R. , 'ANTHOCYANIN 1 of Petunia controls pigment synthesis, vacuolar pH, and seed coat development by genetically distinct mechanisms ' (2002 ) 14 Plant Cell : 2121 -2135 .

    • Search Google Scholar
  • Törökné, A. K., László, E., Chorus, I., Fastner, I., Heinze, R., Padisák, J., Barbosa, F. A. R. (2000) Water quality monitoring by Thamnotoxkit F (™) including cyanobacterial blooms. Water Sci. Technol. 42, 381–385.

    Barbosa F. A. R. , 'Water quality monitoring by Thamnotoxkit F (™) including cyanobacterial blooms ' (2000 ) 42 Water Sci. Technol. : 381 -385 .

    • Search Google Scholar
  • Vasas, G., Gáspár, A., Páger, C., Surányi, G., Máthé, C., M.-Hamvas, M., Borbély, G. (2004) Analysis of cyanobacterials toxins (anatoxin-a, cylindrospermopsin, microcystin-LR) by capillary electrophoresis. Electrophoresis 25, 108–115.

    Borbély G. , 'Analysis of cyanobacterials toxins (anatoxin-a, cylindrospermopsin, microcystin-LR) by capillary electrophoresis ' (2004 ) 25 Electrophoresis : 108 -115 .

    • Search Google Scholar
  • Vasas, G., Gáspár, A., Surányi, G., Batta, G., Gyémánt, G., M.-Hamvas, M., Máthé, C., Grigorszky, I., Molnár, E., Borbély, G. (2002) Capillary electrophoretic assay and purification of cylindrospermopsin, a cyanobacterial toxin from Aphanizomenon ovalisporum, by plant test (Blue-Green Sinapis Test). Anal. Biochem. 302, 95–103.

    Borbély G. , 'Capillary electrophoretic assay and purification of cylindrospermopsin, a cyanobacterial toxin from Aphanizomenon ovalisporum, by plant test (Blue-Green Sinapis Test) ' (2002 ) 302 Anal. Biochem. : 95 -103 .

    • Search Google Scholar
  • Weiss, J., Liebert, H. P., Braune, W. (2000) Influence of microcystin-RR on growth and photosynthetic capacity of the duckweed Lemna minor L. J. Appl. Bot. — Angew. Bot. 74, 100–105.

    Braune W. , 'Influence of microcystin-RR on growth and photosynthetic capacity of the duckweed Lemna minor L ' (2000 ) 74 J. Appl. Bot. — Angew. Bot. : 100 -105 .

    • Search Google Scholar
  • Wharton, P. S., Nicholson, R. L. (2000) Temporal synthesis and radiolabellig of the sorghum 3-deoxyanthocyanidin phytoalexins and the anthocyanin, cyaniding 3-dimalonyl glucoside. New Phytol. 145, 457–469.

    Nicholson R. L. , 'Temporal synthesis and radiolabellig of the sorghum 3-deoxyanthocyanidin phytoalexins and the anthocyanin, cyaniding 3-dimalonyl glucoside ' (2000 ) 145 New Phytol. : 457 -469 .

    • Search Google Scholar
  • White, S. H., Duinvenvoorden, L. J., Fabbro, L. D. (2005) Absence of free-cylindrospermopsin bioconcentration in water thyme (Hydrilla verticillata). B. Environ. Contam. Tox. 75, 574–583.

    Fabbro L. D. , 'Absence of free-cylindrospermopsin bioconcentration in water thyme (Hydrilla verticillata) ' (2005 ) 75 B. Environ. Contam. Tox. : 574 -583 .

    • Search Google Scholar
  • Wiegand, C., Pflugmacher, S. (2005) Ecotoxicological effects of selected cyanobacterial secondary metabolites a short review. Toxicol. Appl. Pharmacol. 203, 201–218.

    Pflugmacher S. , 'Ecotoxicological effects of selected cyanobacterial secondary metabolites a short review ' (2005 ) 203 Toxicol. Appl. Pharmacol. : 201 -218 .

    • Search Google Scholar
  • Yin, L., Huang, J., Li, D., Liu, Y. (2005) Microcystin-RR uptake and ist effects on the growth of submerged macrophyte Vallisneria natans (lour.) hara. Environ. Toxicol. 20, 308–313.

    Liu Y. , 'Microcystin-RR uptake and ist effects on the growth of submerged macrophyte Vallisneria natans (lour.) hara ' (2005 ) 20 Environ. Toxicol. : 308 -313 .

    • Search Google Scholar
  • Collapse
  • Expand

Editorial Board

    1. Csányi, Vilmos (Göd)
    1. Dudits, Dénes (Szeged)
    1. Falus, András (Budapest)
    1. Fischer, Ernő (Pécs)
    1. Gábriel, Róbert (Pécs)
    1. Gulya, Károly (Szeged)
    1. Gulyás, Balázs (Stockholm)
    1. Hajós, Ferenc (Budapest)
    1. Hámori, József (Budapest)
    1. Heszky, László (Gödöllő)
    1. Hideg, Éva (Szeged)
    1. E. Ito (Sanuki)
    1. Janda, Tibor (Martonvásár)
    1. Kavanaugh, Michael P. (Missoula)
    1. Kása, Péter (Szeged)
    1. Klein, Éva (Stockholm)
    1. Kovács, János (Budapest)
    1. Brigitte Mauch-Mani (Neuchâtel)
    1. Nässel, Dick R. (Stockholm)
    1. Nemcsók, János (Szeged)
    1. Péczely, Péter (Gödöllő)
    1. Roberts, D. F. (Newcastle-upon-Tyne)
    1. Sakharov, Dimitri A. (Moscow)
    1. Singh, Meharvan (Fort Worth)
    1. Sipiczky, Mátyás (Debrecen)
    1. Szeberényi, József (Pécs)
    1. Székely, György (Debrecen)
    1. Tari, Irma (Szeged)
    1. Vágvölgyi, Csaba (Szeged),
    1. L. Zaborszky (Newark)

 

Acta Biologica Hungarica
P.O. Box 35
H-8237 Tihany, Hungary
Phone: (36 87) 448 244 ext. 103
Fax: (36 87) 448 006
E-mail: elekes@tres.blki.hu

Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • Chemical Abstracts
  • Current Contents: Agriculture
  • Biology and Environmental Sciences
  • Elsevier BIOBASE
  • Global Health
  • Index Medicus
  • Index Veterinarius
  • Medline
  • Referativnyi Zhurnal
  • Science Citation Index
  • Science Citation Index Expanded (SciSearch)
  • SCOPUS
  • The ISI Alerting Services
  • Zoological Abstracts

 

Acta Biologica Hungarica
Language English
Size  
Year of
Foundation
1950
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5383 (Print)
ISSN 1588-256X (Online)