Acta Biologica Hungarica
Volume/Issue:
Volume 61: Issue 3
Effects of crude oil and oil fractions on the liver P450-dependent monooxygenase activities and antioxidant defence system of different freshwater fish species
Authors:
Aranka Deér University of Szeged Department of Biochemistry and Molecular Biology Szeged Hungary

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Mária Henczová University of Szeged Department of Biochemistry and Molecular Biology Szeged Hungary

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L. Banka University of Szeged Department of Biochemistry and Molecular Biology Szeged Hungary

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Zs. Varanka University of Szeged Department of Biochemistry and Molecular Biology Szeged Hungary

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J. Nemcsók University of Szeged Department of Biochemistry and Molecular Biology Szeged Hungary

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Pages:
262–273
Online Publication Date:
19 Aug 2010
Publication Date:
01 Sep 2010
Article Category:
Research Article
DOI:
https://doi.org/10.1556/abiol.61.2010.3.3
Keywords:
Crude oil; oil fractions; liver P450-dependent monooxygenases; antioxidant defence system; freshwater fish
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The effects of crude oil (Szeged-Algyő, Hungary) and oil fractions (F1: rich in aromatics; F2 fraction: free from aromatics) were investigated on liver CYP1A isoenzymes and antioxidant defence system following their i.p. injection into different freshwater fish species: carp ( Cyprinus carpio L.), silver carp ( Hyphothalmichtys molitrix V.), and European eel ( Anquilla anquilla ). A dose of 2 mL kg −1 crude oil enhanced EROD activity 8-fold in carp and only 5-fold in eel after 3 days. Oil fraction F1 caused only a 2-fold induction in EROD activity only in carp, while F2 fraction caused significant inhibition in all three investigated fish species. The antioxidant parameters [lipid peroxidation (LP), catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione (GSH)] were measured following the treatment. A decrease of 50% in CAT activity was observed after oil treatment. The GSH level enhanced, resulting the protective effects against LP. The same dose of crude oil but a longer duration time resulted in lower CYP1A induction in carp and antioxidant parameters had returned close to control. In all treatments the EROD isoenzymes proved to be more sensitive and the effects of oil treatment showed species to be different. Carp proved to be more sensitive than eel or silver carp.

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Cover Acta Biologica Hungarica
Acta Biologica Hungarica
Print ISSN:
0236-5383
Online ISSN:
1588-256X

Senior editors

Editor(s)-in-Chief: Elekes, Károly

Editorial Board

    1. Csányi, Vilmos (Göd)
    1. Dudits, Dénes (Szeged)
    1. Falus, András (Budapest)
    1. Fischer, Ernő (Pécs)
    1. Gábriel, Róbert (Pécs)
    1. Gulya, Károly (Szeged)
    1. Gulyás, Balázs (Stockholm)
    1. Hajós, Ferenc (Budapest)
    1. Hámori, József (Budapest)
    1. Heszky, László (Gödöllő)
    1. Hideg, Éva (Szeged)
    1. E. Ito (Sanuki)
    1. Janda, Tibor (Martonvásár)
    1. Kavanaugh, Michael P. (Missoula)
    1. Kása, Péter (Szeged)
    1. Klein, Éva (Stockholm)
    1. Kovács, János (Budapest)
    1. Brigitte Mauch-Mani (Neuchâtel)
    1. Nässel, Dick R. (Stockholm)
    1. Nemcsók, János (Szeged)
    1. Péczely, Péter (Gödöllő)
    1. Roberts, D. F. (Newcastle-upon-Tyne)
    1. Sakharov, Dimitri A. (Moscow)
    1. Singh, Meharvan (Fort Worth)
    1. Sipiczky, Mátyás (Debrecen)
    1. Szeberényi, József (Pécs)
    1. Székely, György (Debrecen)
    1. Tari, Irma (Szeged)
    1. Vágvölgyi, Csaba (Szeged),
    1. L. Zaborszky (Newark)

 

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Acta Biologica Hungarica
Language English
Size  
Year of
Foundation		 1950
Publication
Programme		 changed title
Volumes
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per Year		  
Founder Magyar Tudományos Akadémia
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Address		 H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
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ISSN 0236-5383 (Print)
ISSN 1588-256X (Online)

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