View More View Less
  • 1 Zagazig University Microbiology Department, Faculty of Science Zagazig Egypt
  • | 2 Egyptian Atomic Energy Authority Inshas, Cairo Egypt
Restricted access

The potency for production of cystathionine γ-lyase (CGL) by the fungal isolates was screened. Among the tested twenty-two isolates, Aspergillus carneus was the potent CGL producer (6.29 U/mg), followed by A. ochraceous (6.03 U/mg), A. versicolor (2.51 U/mg), A. candidus (2.12 U/mg), A. niveus and Penicillium notatum (2.0 U/mg). The potent six isolates producing CGL was characterized morphologically, A. carneus KF723837 was further molecularly characterized based on the sequence of 18S–28S rDNA. Upon sulfur starvation, the yield of A. carneus extracellular CGL was increased by about 1.7- and 4.1-fold comparing to non-sulfur starved and L-methionine free medium, respectively. Also, the uptake of L-methionine was duplicated upon sulfur starvation, assuming the activation of specific transporters for L-methionine and efflux of CGL. Also, the intracellular thiols and GDH activity of A. carneus was strongly increased by S starvation, revealing the activation of in vivo metabolic antioxidant systems. Upon irradiation of A. carneus by 2.0 kGy of γ-rays, the activity of CGL was increased by two-fold, regarding to control, with an obvious decreases on its yield upon further doses. Practically, CGL activity from the solid A. carneus cultures, using rice bran as substrate, was increased by 1.2-fold, comparing to submerged cultures, under optimum conditions.

  • Aziz, N.H., Mahrous, S. R. (2004) Effect of γ-irradiation on aflatoxin B1 production by A. flavus and chemical composition of three crop seeds. Nahrung-Food, 48, 234–238.

    Mahrous S. R. , 'Effect of γ-irradiation on aflatoxin B1 production by A. flavus and chemical composition of three crop seeds ' (2004 ) 48 Nahrung-Food : 234 -238.

    • Search Google Scholar
  • Benko, P. V., Wood, T. C., Segel, I. H. (1967) Specificity and regulation of the methionine transport in filamentous fungi. Arch. Biochem. Biophys. 122, 783–804.

    Segel I. H. , 'Specificity and regulation of the methionine transport in filamentous fungi ' (1967 ) 122 Arch. Biochem. Biophys. : 783 -804.

    • Search Google Scholar
  • Booth, C. (1971) The Genus Fusarium. Commonwealth Mycological Institute, Lincoln, LIN, United Kingdom.

    Booth C. , '', in The Genus Fusarium , (1971 ) -.

  • Boysen, M. E., Jacobsson, K.-G., Schnurer, J. (2000) Molecular identification of species from the Penicillium requeforti group associated with spoiled animal feed. Appl. Environ. Micobiol. 66, 1525–1526.

    Schnurer J. , 'Molecular identification of species from the Penicillium requeforti group associated with spoiled animal feed ' (2000 ) 66 Appl. Environ. Micobiol. : 1525 -1526.

    • Search Google Scholar
  • Bruinenberg, P. G., De Roou, G., Limsowtin, G. (1997) Purification and characterization of cystathionine gamma lyase from Lactococcus lactis cremoris SK11: possible role in flavor compound formation during cheese maturation. Appl. Environ. Microbiol. 63, 561–566.

    Limsowtin G. , 'Purification and characterization of cystathionine gamma lyase from Lactococcus lactis cremoris SK11: possible role in flavor compound formation during cheese maturation ' (1997 ) 63 Appl. Environ. Microbiol. : 561 -566.

    • Search Google Scholar
  • Chen, S. C. A., Halliday, C. L., Meyer, W. (2002) A review of nucleic acid-based diagnostic tests for systemic mycoses with an emphasis on polymerase chain reaction-based assays. Med. Mycol. 40, 333–357.

    Meyer W. , 'A review of nucleic acid-based diagnostic tests for systemic mycoses with an emphasis on polymerase chain reaction-based assays ' (2002 ) 40 Med. Mycol. : 333 -357.

    • Search Google Scholar
  • De-Aguirre, L., Hurst, S. F., Choi, J. S., Shin, J. H., Hinrikson, H. P., Morrison, C. J. (2004) Rapid differentiation of Aspergillus species from other medically important opportunistic molds and yeasts by PCR-enzyme immunoassay. J. Clin. Microbiol. 42, 3495–3504.

    Morrison C. J. , 'Rapid differentiation of Aspergillus species from other medically important opportunistic molds and yeasts by PCR-enzyme immunoassay ' (2004 ) 42 J. Clin. Microbiol. : 3495 -3504.

    • Search Google Scholar
  • De Angelis, M., Curtin, A. C., Mac Sweeney, P., Faccia, M., Gobbetti, M. (2002) Lactobacillus reuteri DSM 20016: purification and characterization of cystathionine gamma lyase and use as adjunct starter in cheese making. J. Dairy Res. 69, 255–267.

    Gobbetti M. , 'Lactobacillus reuteri DSM 20016: purification and characterization of cystathionine gamma lyase and use as adjunct starter in cheese making ' (2002 ) 69 J. Dairy Res. : 255 -267.

    • Search Google Scholar
  • Delavier-Klutchko, C., Flavin, M. (1965) Enzymatic synthesis and cleavage of cystathionine in fungi and bacteria. J. Biol. Chem. 240, 2537–2549.

    Flavin M. , 'Enzymatic synthesis and cleavage of cystathionine in fungi and bacteria ' (1965 ) 240 J. Biol. Chem. : 2537 -2549.

    • Search Google Scholar
  • Domsch, K. H., Gams, W., Anderson, T. (1980) Compendium of Soil Fungi. Academic Press. IHW Verlag, Eching, Germany.

    Anderson T. , '', in Compendium of Soil Fungi , (1980 ) -.

  • Domsch, K. H., Gams, W., Anderson, T. (2007) Compendium of Soil Fungi. 2nd Edition. IHW Verlag, Eching, Germany.

    Anderson T. , '', in Compendium of Soil Fungi , (2007 ) -.

  • Dupont, J., Magnin, S., Marti, A., Brousse, M. (1999) Molecular tools for identification of Penicillium starter cultures used in food industry. Int. J. Food Microbiol. 49, 109–118.

    Brousse M. , 'Molecular tools for identification of Penicillium starter cultures used in food industry ' (1999 ) 49 Int. J. Food Microbiol. : 109 -118.

    • Search Google Scholar
  • Ellis, M. B. (1971) Dematiaceous Hyphomycetes. Commonwealth Mycological Institute, Kew, Surrey, England.

    Ellis M. B. , '', in Dematiaceous Hyphomycetes , (1971 ) -.

  • El-Sayed, A. S. A., Khalaf, S. A., Aziz, H. A. (2013) Characterization of homocysteine γ-lyase from submerged and solid cultures of Aspergillus fumigatus ASH (JX006238). J. Microbiol. Biotechnol. 23, 499–510.

    Aziz H. A. , 'Characterization of homocysteine γ-lyase from submerged and solid cultures of Aspergillus fumigatus ASH (JX006238) ' (2013 ) 23 J. Microbiol. Biotechnol. : 499 -510.

    • Search Google Scholar
  • El-Sayed, A. S. A. (2009) L-Methioninase production by Aspergillus flavipes under solid-state fermentation. J. Basic Microbiol. 49, 331–341.

    El-Sayed A. S. A. , 'L-Methioninase production by Aspergillus flavipes under solid-state fermentation ' (2009 ) 49 J. Basic Microbiol. : 331 -341.

    • Search Google Scholar
  • El-Sayed, A. S. A. (2010) Microbial L-methioninase, molecular characterization and therapeutic applications. Appl. Microbiol. Biotechnol. 86, 445–467.

    El-Sayed A. S. A. , 'Microbial L-methioninase, molecular characterization and therapeutic applications ' (2010 ) 86 Appl. Microbiol. Biotechnol. : 445 -467.

    • Search Google Scholar
  • El-Sayed, A. S. A. (2011) Purification and characterization of a new L-methioninase from Aspergillus flavipes under solid state fermentation. J. Microbiol. 49, 130–140.

    El-Sayed A. S. A. , 'Purification and characterization of a new L-methioninase from Aspergillus flavipes under solid state fermentation ' (2011 ) 49 J. Microbiol. : 130 -140.

    • Search Google Scholar
  • El-Sayed, A. S. A., Shindia, A. A., Zaher, Y. (2012) L-Amino acid oxidase from filamentous fungi: screening and optimization. Ann. Microbiol. 62, 773–784.

    Zaher Y. , 'L-Amino acid oxidase from filamentous fungi: screening and optimization ' (2012 ) 62 Ann. Microbiol. : 773 -784.

    • Search Google Scholar
  • Endres, W., Wuttge, B. (1978) Occurrence of secondary cystathioninuria in children with inherited metabolic disorders, liver diseases, neoplasms, cystic fibrosis and celiac disease. Eur. J. Pediatr. 129, 29–35.

    Wuttge B. , 'Occurrence of secondary cystathioninuria in children with inherited metabolic disorders, liver diseases, neoplasms, cystic fibrosis and celiac disease ' (1978 ) 129 Eur. J. Pediatr. : 29 -35.

    • Search Google Scholar
  • Fang, X., Yano, S., Inoue, H., Sawayama, S. (2009) Strain improvement of Acremonium cellulolyticus for cellulase production by mutation. J. Biosci. Bioeng. 107, 256–261.

    Sawayama S. , 'Strain improvement of Acremonium cellulolyticus for cellulase production by mutation ' (2009 ) 107 J. Biosci. Bioeng. : 256 -261.

    • Search Google Scholar
  • Flavin, M. (1975) Metabolism of Sulfur Compounds. Academic Press, New York.

    Flavin M. , '', in Metabolism of Sulfur Compounds , (1975 ) -.

  • Florez, A. B., Alvarez-Martin, P., Lopez-Diaz, T. M. Mayo, B. (2007) Morphotypic and molecular identification of filamentous fungi from Spanish blue-veined cabrales cheese, and typing of Penicillium requeforti and Geotrichum candidum isolates. Inter. Dairy J. 17, 350–357.

    Mayo B. , 'Morphotypic and molecular identification of filamentous fungi from Spanish blue-veined cabrales cheese, and typing of Penicillium requeforti and Geotrichum candidum isolates ' (2007 ) 17 Inter. Dairy J. : 350 -357.

    • Search Google Scholar
  • Gadgil, N. J., Daginawala, H. F., Chakakrabarti, T., Khanna, P. (1995) Enhanced cellulase production by mutant of Trichoderma reesei. Enzyme Microb. Technol. 17, 942–946.

    Khanna P. , 'Enhanced cellulase production by mutant of Trichoderma reesei ' (1995 ) 17 Enzyme Microb. Technol. : 942 -946.

    • Search Google Scholar
  • Gente, S., La Carbona, S. Guéguen, M. (2007) Levels of cystathionine γ-lyase production by Geotrichum candidum in synthetic media and correlation with the presence of sulphur flavours in cheese. Int. J. Food Microbiol. 114, 136–142.

    Guéguen M. , 'Levels of cystathionine γ-lyase production by Geotrichum candidum in synthetic media and correlation with the presence of sulphur flavours in cheese ' (2007 ) 114 Int. J. Food Microbiol. : 136 -142.

    • Search Google Scholar
  • Harris, H., Penrose, L. S., Thomas, D. H. H. (1959) Cystathioninuria. Ann. Hum. Genet. 23, 442–453.

    Thomas D. H. H. , 'Cystathioninuria ' (1959 ) 23 Ann. Hum. Genet. : 442 -453.

  • Henry, T., Iwen, P. C., Hinrichs, S. H. (2000) Identification of Aspergillus species using internal transcribed spacer regions 1 and 2. J. Clin. Microbiol. 38, 1510–1515.

    Hinrichs S. H. , 'Identification of Aspergillus species using internal transcribed spacer regions 1 and 2 ' (2000 ) 38 J. Clin. Microbiol. : 1510 -1515.

    • Search Google Scholar
  • Hiraishi, H., Tsuyoshi Miyake, T., Ono, B. I. (2008) Transcriptional regulation of Saccharomyces cerevisiae CYS3 encoding cystathionine γ-lyase, Curr. Genet. 53, 225–234.

    Ono B. I. , 'Transcriptional regulation of Saccharomyces cerevisiae CYS3 encoding cystathionine γ-lyase, Curr ' (2008 ) 53 Genet. : 225 -234.

    • Search Google Scholar
  • Irmler, S., Raboud, S., Beisert, B., Rauhut, D., Berthoud, H. (2008) Cloning and characterization of two Lactobacillus casei genes encoding a cystathionine lyase. Appl. Environ. Microbiol. 74, 99.

    Berthoud H. , 'Cloning and characterization of two Lactobacillus casei genes encoding a cystathionine lyase ' (2008 ) 74 Appl. Environ. Microbiol. : 99 -.

    • Search Google Scholar
  • Kebeish, R., El-Sayed, A. S. A. (2012) Morphological and molecular characterization of L-methioninase producing Aspergillus species. Af. J. Microbiol. 11, 15280–15290.

    El-Sayed A. S. A. , 'Morphological and molecular characterization of L-methioninase producing Aspergillus species ' (2012 ) 11 Af. J. Microbiol. : 15280 -15290.

    • Search Google Scholar
  • Khalaf, S., El-Sayed, A. S. A. (2009) L-Methioninase production by filamentous fungi: screening and optimization under submerged conditions. Curr. Microbiol. 58, 219–226.

    El-Sayed A. S. A. , 'L-Methioninase production by filamentous fungi: screening and optimization under submerged conditions ' (2009 ) 58 Curr. Microbiol. : 219 -226.

    • Search Google Scholar
  • Klich, M. A., Pitt, J. I. (1992) A Laboratory Guide to the Common Aspergillus Species and their Teleomorphs. Common Wealth Scientific and Industrial Research Organization, Division of Food Processing, North Ryde, Australia.

    Pitt J. I. , '', in A Laboratory Guide to the Common Aspergillus Species and their Teleomorphs , (1992 ) -.

  • Latifian, M., Hamidin-Esfahani, Z., Barzegar, M. (2007) Evaluation of culture conditions for cellulos production by two Trichoderma reesei mutants under solid-state fermentation conditions. Bioresour. Technol. 98, 1–4.

    Barzegar M. , 'Evaluation of culture conditions for cellulos production by two Trichoderma reesei mutants under solid-state fermentation conditions ' (2007 ) 98 Bioresour. Technol. : 1 -4.

    • Search Google Scholar
  • Lowry, O. H., Rosenrough, N. J., Farr, A. L., Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265–275.

    Randall R. J. , 'Protein measurement with the Folin phenol reagent ' (1951 ) 193 J. Biol. Chem. : 265 -275.

    • Search Google Scholar
  • Mansouri-Bauly, H., Sýkorová, Z., Scheerer, U., Kopriva, S. (2006) Sulfur uptake in the ectomycorrhizal fungus Laccaria bicolor S238N. Mycorrhiza 16, 421–427.

    Kopriva S. , 'Sulfur uptake in the ectomycorrhizal fungus Laccaria bicolor S238N ' (2006 ) 16 Mycorrhiza : 421 -427.

    • Search Google Scholar
  • Nagasawa, T., Kansaki, H., Yamada, H. (1984) Cystathionine γ-lyase of Streptomyces phaeochromogenes. J. Biol. Chem. 259, 10393–10403.

    Yamada H. , 'Cystathionine γ-lyase of Streptomyces phaeochromogenes ' (1984 ) 259 J. Biol. Chem. : 10393 -10403.

    • Search Google Scholar
  • Paszewski, A., Grabski, J. (1973) Studies on β-cystathionase and O-acetylhomoserine sulfhydrylase as the enzymes of alternative methionine biosynthetic pathways. Acta Biochim. Pol. 20, 159–168.

    Grabski J. , 'Studies on β-cystathionase and O-acetylhomoserine sulfhydrylase as the enzymes of alternative methionine biosynthetic pathways ' (1973 ) 20 Acta Biochim. Pol. : 159 -168.

    • Search Google Scholar
  • Perry, T. L., Robinson, G. C., Teasdale, J. M., Hansen, S. (1967) Concurrence of cystathioninuria, nephrogenic diabetes insipidus and severe anemia. N. Engl. J. Med. 276, 721–725.

    Hansen S. , 'Concurrence of cystathioninuria, nephrogenic diabetes insipidus and severe anemia ' (1967 ) 276 N. Engl. J. Med. : 721 -725.

    • Search Google Scholar
  • Pitt, Q. W. (1979) The Genus Penicillium and its Teleomorphic States Eupenicillium and Talaromyces. Academic Press, London.

    Pitt Q. W. , '', in The Genus Penicillium and its Teleomorphic States Eupenicillium and Talaromyces , (1979 ) -.

  • Rajoka, M. I. (2005) Double mutants of Cellulomonas biazotea for production of cellulases and hemicellulases following growth on straw of a perennial grass. World J. Microbiol. Biotechnol. 21, 1063–1066.

    Rajoka M. I. , 'Double mutants of Cellulomonas biazotea for production of cellulases and hemicellulases following growth on straw of a perennial grass ' (2005 ) 21 World J. Microbiol. Biotechnol. : 1063 -1066.

    • Search Google Scholar
  • Raper, K. B., Fennell, D. I. (1965) The Genus Aspergillus. The Williams and Wilkins Company, Baltimore.

    Fennell D. I. , '', in The Genus Aspergillus , (1965 ) -.

  • Rifai, M. A. (1969) A Revision of the Genus Trichoderma. Commonwealth Mycological Institute, Kew.

    Rifai M. A. , '', in A Revision of the Genus Trichoderma , (1969 ) -.

  • Rolland, S. G., Bruel, C. A. (2008) Sulfur and nitrogen regulation of the protease-encoding ACP1 gene in the fungus Botrytis cinerea: correlation with a phospholipase D activity. Microbiology 154, 1464–1473.

    Bruel C. A. , 'Sulfur and nitrogen regulation of the protease-encoding ACP1 gene in the fungus Botrytis cinerea: correlation with a phospholipase D activity ' (2008 ) 154 Microbiology : 1464 -1473.

    • Search Google Scholar
  • Smacchi, E., Gobbetti, M. (1998) Purification and characterization of cystathionine gamma lyase from Lactobacillus fermentum DT41. FEMS Microbiol. Lett. 166, 197–202.

    Gobbetti M. , 'Purification and characterization of cystathionine gamma lyase from Lactobacillus fermentum DT41 ' (1998 ) 166 FEMS Microbiol. Lett. : 197 -202.

    • Search Google Scholar
  • Uren, J. R. (1987) Cystathionine γ-lyase from Escherichia coli. Methods Enzymol. 143, 483–486.

    Uren J. R. , 'Cystathionine γ-lyase from Escherichia coli ' (1987 ) 143 Methods Enzymol. : 483 -486.

    • Search Google Scholar
  • Yang, G. (2011) Hydrogen sulfide in cell survival: a double-edged sword. Expert Rev. Clin. Pharmacol. 4, 33–47.

    Yang G. , 'Hydrogen sulfide in cell survival: a double-edged sword ' (2011 ) 4 Expert Rev. Clin. Pharmacol. : 33 -47.

    • Search Google Scholar
  • Yang, G., Wu, L., Bryan, S., Khaper, N., Mani, S. Wang, R. (2010) Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells. Cardiovasc Res. 86, 487–495.

    Wang R. , 'Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells ' (2010 ) 86 Cardiovasc Res. : 487 -495.

    • Search Google Scholar

Editorial Board

      Csányi, Vilmos (Göd)
      Dudits, Dénes (Szeged)
      Falus, András (Budapest)
      Fischer, Ernő (Pécs)
      Gábriel, Róbert (Pécs)
      Gulya, Károly (Szeged)
      Gulyás, Balázs (Stockholm)
      Hajós, Ferenc (Budapest)
      Hámori, József (Budapest)
      Heszky, László (Gödöllő)
      Hideg, Éva (Szeged)
      E. Ito (Sanuki)
      Janda, Tibor (Martonvásár)
      Kavanaugh, Michael P. (Missoula)
      Kása, Péter (Szeged)
      Klein, Éva (Stockholm)
      Kovács, János (Budapest)
      Brigitte Mauch-Mani (Neuchâtel)
      Nässel, Dick R. (Stockholm)
      Nemcsók, János (Szeged)
      Péczely, Péter (Gödöllő)
      Roberts, D. F. (Newcastle-upon-Tyne)
      Sakharov, Dimitri A. (Moscow)
      Singh, Meharvan (Fort Worth)
      Sipiczky, Mátyás (Debrecen)
      Szeberényi, József (Pécs)
      Székely, György (Debrecen)
      Tari, Irma (Szeged)
      Vágvölgyi, Csaba (Szeged),
      L. Zaborszky (Newark)

 

Acta Biologica Hungarica
P.O. Box 35
H-8237 Tihany, Hungary
Phone: (36 87) 448 244 ext. 103
Fax: (36 87) 448 006
E-mail: elekes@tres.blki.hu

Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • Chemical Abstracts
  • Current Contents: Agriculture
  • Biology and Environmental Sciences
  • Elsevier BIOBASE
  • Global Health
  • Index Medicus
  • Index Veterinarius
  • Medline
  • Referativnyi Zhurnal
  • Science Citation Index
  • Science Citation Index Expanded (SciSearch)
  • SCOPUS
  • The ISI Alerting Services
  • Zoological Abstracts

 

Acta Biologica Hungarica
Language English
Size  
Year of
Foundation
1950
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5383 (Print)
ISSN 1588-256X (Online)