Authors:
Kaliyaperumal Rekha Tamil University, Thanjavur – 613005, Tamil Nadu, India

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Chandran Sivasubramanian Tamil University, Thanjavur – 613005, Tamil Nadu, India

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Muthu Thiruvengadam Konkuk University, Seoul – 143 701,, South Korea

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Phenolic contents, antioxidant and antimicrobial activities were determined by two samples from summer (June) and winter (December) seasons of Ligularia fischeri var. spiciformis Nakai. A total of 24 phenolic compounds were identified by ultra-performance liquid chromatography (UPLC) analysis. Myricetin (1964.35 and 1829.12 μg/g) was the most dominant flavonol compared to quercetin and kaempferol. Salicylic acid (222.80 and 215.25 μg/g) was the most important phenolic compound compared to pyrogallol, caffeic acid, gentisic acid, o-coumaric acid, gallic acid, protocatechuic acid and ferulic acid in summer (June) and winter (December) seasons. Phenolic contents and antioxidant capacities were estimated for the various solvent extracts (petroleum ether, butanol, ethyl acetate, methanol and water). Ethyl acetate extract exhibited the highest phenolic (332.64 and 299.44 mg/g gallic acid equivalent) and flavonoid contents (5.72 and 5.29 mg/g quercetin equivalent) and also the strongest antioxidant activity in summer and winter seasons. Due to these metabolic variations, the antioxidant and antimicrobial activities were increased with summer seasons compared to winter seasons. Our study shows that the samples collected in June had higher phenolic compounds, stronger antioxidative and antimicrobial activity than the samples of L. fischeri leaf extracts collected in December.

  • 1.

    Bae, J. H., Yu, S. O., Kim, Y. M., Chon, S. U., Kim, B. W., Heo, B. G. (2009) Physiological activity of methanol extracts from Ligularia fischeri and their hyperplasia inhibition activity of cancer cell. J. Biol. Environ. Cont. 18, 6773.

    • Search Google Scholar
    • Export Citation
  • 2.

    Boyle, S. P., Dobson, V. L., Duthie, S. J., Kyle, J. A., Collins, A. R. (2000) Absorption and DNA protective effects of flavonoid glycosides from an onion meal. Euro. J. Nutr. 39, 213223.

    • Search Google Scholar
    • Export Citation
  • 3.

    Carvalho, I. S., Cavaco, T., Brodelius, M. (2011) Phenolic composition and antioxidant capacity of six Artemisia species. Industrial Crops Prod. 33, 382388.

    • Search Google Scholar
    • Export Citation
  • 4.

    Choi, E. M., Ding, Y., Nguyen, H. T., Park, S. H., Kim, Y. H. (2007) Antioxidant activity of gomchi (Ligularia fischeri) leaves. Food Sci. Biotechnol. 16, 710714.

    • Search Google Scholar
    • Export Citation
  • 5.

    Choi, E. M., Kim, Y. H. A. (2008) Preliminary study of the effects of an extract of Ligularia fischeri leaves on type II collagen-induced arthritis in DBA/1J mice. Food Chem. Toxicol. 46, 375379.

    • Search Google Scholar
    • Export Citation
  • 6.

    Elzaawely, A. A., Xuan, T. D., Tawata, S. (2005) Antioxidant and antibacterial activities of Rumex japonicus HOUTT. aerial parts. Biol. Pharm. Bull. 28, 22252230.

    • Search Google Scholar
    • Export Citation
  • 7.

    Ham, S. S., Lee, S. Y., Oh, D. H., Jung, S. W., Kim, S. H., Jeong, C. H., Kang, I. J. (1998) Cytotoxicity of Ligularia fischeri extracts. Kor. Soc. Food Sci. Nutr. 27, 987992.

    • Search Google Scholar
    • Export Citation
  • 8.

    Hilton, P. J., Palmer-Jones, R., Ellis, R. T. (1973) Effects of season and nitrogen fertilizer upon the flavanol composition and tea making quality of fresh shoots of tea (Camellia sinensis L.) in central Africa. J. Sci. Food Agri. 24, 819826.

    • Search Google Scholar
    • Export Citation
  • 9.

    Janssen, K., Mensink, R., Cox, F., Harryvan, J., Hovenior, R., Hollman, P., Katan, M. (1998) Effects of the flavonoids quercetin and apigenin on hemostasis in healthy volunteers: results from an in vitro and a dietary supplement study. Am. J. Clinic. Nutr. 2, 255262.

    • Search Google Scholar
    • Export Citation
  • 10.

    Jayanthi, P., Lalitha, P. (2011) Reducing power of the solvent extracts of Eichhornia crassipes (Mart.) Solms. Int. J. Pharm. Pharmaceutical Sci. 3, 126128.

    • Search Google Scholar
    • Export Citation
  • 11.

    Jeong, S. W., Kim, E. J., Hwangbo, H. J., Ham, S. S. (1998) Effects of Ligularia fischeri extracts on oxidation of low density lipoprotein. Kor. J. Food Sci. Tech. 30, 12141221.

    • Search Google Scholar
    • Export Citation
  • 12.

    Kim, S. M., Jeon, J. S., Kang, S. W., Jung, Y. J., Ly, L. N., Um, B. H. (2012) Content of antioxidative caffeoylquinic acid derivatives in field-grown Ligularia fischeri (Ledeb.) Turcz and responses to sunlight. J. Agric. Food Chem. 60, 55975603.

    • Search Google Scholar
    • Export Citation
  • 13.

    Lee, K. T., Koo, S. J., Jung, S. H., Choi, J. W., Jung, H. J., Park, H. J. (2002) Structure of three new terpenoids, spiciformisins a and b, and monocyclosqualene, isolated from the herbs of Ligulariafischeri var. spiciformis and cytotoxicity. Arch. Pharm. Res. 25, 820823.

    • Search Google Scholar
    • Export Citation
  • 14.

    Lee, Y. J., Thiruvengadam, M., Chung, I. M., Nagella, P. (2013) Polyphenol composition and antioxidant activity from the vegetable plant Artemisia absinthium L. Aust. J. Crop Sci. 7, 19211926.

    • Search Google Scholar
    • Export Citation
  • 15.

    Nagella, P., Thiruvengadam, M., Ahmad, A., Chung, I. M. (2014) UHPLC analysis of polyphenol composition and antioxidant activity from different solvent extracts of Coriandrum sativum seeds cultivated in Korea. Asian J. Chem. 26, 63516356.

    • Search Google Scholar
    • Export Citation
  • 16.

    Pai, S. R., Masingraj, S., Nimbalkar, Pawar, N. V., Patil, R. P., Dixit, G. B. (2010) Seasonal discrepancy in phenolic content and antioxidant properties from bark of Nothapodytes nimmoniana (Grah.) Mabb. Int. J. Pharma Bio Sci. 1, 117.

    • Search Google Scholar
    • Export Citation
  • 17.

    Pattison, D. J., Silman, A. J., Goodson, N. J., Lunt, M., Bunn, D., Luben, R., Welch, A., Bingham, S., Khaw, K. T., Day, N., Symmons, D. P. (2004) Vitamin C and the risk of developing inflammatory polyarthritis: Prospective nested case-control study. Ann. Rheumatic Diseases 63, 843847.

    • Search Google Scholar
    • Export Citation
  • 18.

    Ross, J., Kasum, C. (2002) Dietary flavonoids: Bioavailability, metabolic effects, and safety. Ann. Rev. Nutr. 22, 1934.

  • 19.

    Thiruvengadam, M., Chung, I. M. (2015) Selenium, putrescine, and cadmium influence health-promoting phytochemicals and molecular-level effects on turnip (Brassica rapa ssp. rapa). Food Chem. 173, 185193.

    • Search Google Scholar
    • Export Citation
  • 20.

    Thiruvengadam, M., Praveen, N., Maria John, K. M., Yang, Y. S., Kim, S. H., Chung, I. M. (2014a) Establishment of Momordica charantia hairy root cultures for the production of phenolic compounds and determination of their biological activities. Plant Cell Tissue Org. Cult. 118, 545557.

    • Search Google Scholar
    • Export Citation
  • 21.

    Thiruvengadam, M., Praveen, N., Yu, B. R., Kim, S. H., Chung, I. M. (2014b) Polyphenol composition and antioxidant capacity from different extracts of Aster scaber. Acta Biol. Hung. 65, 144155.

    • Search Google Scholar
    • Export Citation
  • 22.

    Waladkhani, A., Clemens, M. R. (1998) Effect of dietary phytochemicals on cancer development. International J. Molecular Med. 1, 747753.

    • Search Google Scholar
    • Export Citation
  • 23.

    Wong, P. Y. Y., Kitts, D. D. (2006) Studies on the dual antioxidant and antibacterial properties of parsley (Petroselinum crispum) and cilantro (Coriandrum sativum) extracts. Food Chem. 97, 505515.

    • Search Google Scholar
    • Export Citation
  • 24.

    Yao, L., Caffin, N., D’Arcy, B., Jiang, Y., Shi, J., Sinaganusong, R., Liu, X., Datta, N., Kakuda, Y., Xu, Y. (2005) Seasonal variations of phenolic compounds in Australia-grown tea (Camellia sinensis). J . Agric. Food Chem. 53, 64776483.

    • Search Google Scholar
    • Export Citation
  • 25.

    Zhang, W. J., Qi, H. Y., Shi, Y. P. (2010) Norsesquiterpene derivatives from the roots of Ligularia fischeri. Planta Med. 76, 159164.

    • Search Google Scholar
    • Export Citation
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Editorial Board

    1. Csányi, Vilmos (Göd)
    1. Dudits, Dénes (Szeged)
    1. Falus, András (Budapest)
    1. Fischer, Ernő (Pécs)
    1. Gábriel, Róbert (Pécs)
    1. Gulya, Károly (Szeged)
    1. Gulyás, Balázs (Stockholm)
    1. Hajós, Ferenc (Budapest)
    1. Hámori, József (Budapest)
    1. Heszky, László (Gödöllő)
    1. Hideg, Éva (Szeged)
    1. E. Ito (Sanuki)
    1. Janda, Tibor (Martonvásár)
    1. Kavanaugh, Michael P. (Missoula)
    1. Kása, Péter (Szeged)
    1. Klein, Éva (Stockholm)
    1. Kovács, János (Budapest)
    1. Brigitte Mauch-Mani (Neuchâtel)
    1. Nässel, Dick R. (Stockholm)
    1. Nemcsók, János (Szeged)
    1. Péczely, Péter (Gödöllő)
    1. Roberts, D. F. (Newcastle-upon-Tyne)
    1. Sakharov, Dimitri A. (Moscow)
    1. Singh, Meharvan (Fort Worth)
    1. Sipiczky, Mátyás (Debrecen)
    1. Szeberényi, József (Pécs)
    1. Székely, György (Debrecen)
    1. Tari, Irma (Szeged)
    1. Vágvölgyi, Csaba (Szeged),
    1. L. Zaborszky (Newark)

 

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Acta Biologica Hungarica
Language English
Size  
Year of
Foundation
1950
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Magyar Tudományos Akadémia
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Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
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H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
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Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5383 (Print)
ISSN 1588-256X (Online)