Authors:
,
,
,
, and
Dragana Jakovljević
draganajakovljevic@ymail.com
Dragana Jakovljević
Faculty of Science, University of Kragujevac, Radoja Domanovića No. 12, 34000 Kragujevac, Republic of Serbia
Search for other papers by Dragana Jakovljević in
Current site
Google Scholar
PubMed
Search for other papers by Dragana Jakovljević in
Current site
Google Scholar
PubMed
Sava Vasić
Sava Vasić
Faculty of Science, University of Kragujevac, Radoja Domanovića No. 12, 34000 Kragujevac, Republic of Serbia
Search for other papers by Sava Vasić in
Current site
Google Scholar
PubMed
Search for other papers by Sava Vasić in
Current site
Google Scholar
PubMed
Milan Stanković
Milan Stanković
Faculty of Science, University of Kragujevac, Radoja Domanovića No. 12, 34000 Kragujevac, Republic of Serbia
Search for other papers by Milan Stanković in
Current site
Google Scholar
PubMed
Search for other papers by Milan Stanković in
Current site
Google Scholar
PubMed
Ljiljana Čomić
Ljiljana Čomić
Faculty of Science, University of Kragujevac, Radoja Domanovića No. 12, 34000 Kragujevac, Republic of Serbia
Search for other papers by Ljiljana Čomić in
Current site
Google Scholar
PubMed
Search for other papers by Ljiljana Čomić in
Current site
Google Scholar
PubMed
Marina Topuzović
Marina Topuzović
Faculty of Science, University of Kragujevac, Radoja Domanovića No. 12, 34000 Kragujevac, Republic of Serbia
Search for other papers by Marina Topuzović in
Current site
Google Scholar
PubMed
Search for other papers by Marina Topuzović in
Current site
Google Scholar
PubMed
The antioxidant, antimicrobial activity, total phenolic content and flavonoid concentration of Seseli rigidum Waldst. et Kit. were evaluated. Five different extracts of the aboveground plant parts were obtained by extraction with distilled water, methanol, acetone, ethyl acetate and petroleum ether. Total phenols were determined using the Folin-Ciocalteu’s reagent, with the highest values obtained in the acetone extract (102.13 mg GAE/g). The concentration of flavonoids, determined by using a spectrophotometric method with aluminum chloride and expressed in terms of rutin equivalent, was also highest in the acetone extracts (291.58 mg RUE/g). The antioxidant activity was determined in vitro using DPPH reagent. The greatest antioxidant activity was expressed in the aqueous extract (46.15 μg/ml). In vitro antimicrobial activities were determined using a microdilution analysis method; minimum inhibitory concentration (MIC) and minimum microbicidal concentration (MMC) were determined. Methanolic extract had the greatest influence on bacilli (MIC at 0.0391 mg/ml), but the best antimicrobial effect had acetone and ethyl acetate extracts considering their broad impact on bacteria. According to our research, S. rigidum can be regarded as promising candidate for natural plant source with high value of biological compounds.
ProCite
RefWorks
Reference Manager
BibTeX
Zotero
EndNote
-
1.
Andrews, J. M. (2005) BSAC standardized disc susceptibility testing method (version 4). J. Antimicrob. Chemother. 56, 60–76.
-
2.
Ball, P. W. (1968) Seseli. In: Tutin, T. G., Heywood, V. H., Burges, N. A., Moore, D. M., Valentine, D. H., Walters, S. M., Webb, D. A., Flora Europaea II, Cambridge University Press, Cambridge, pp. 334–338.
-
3.
Bulatović, V. M., Šavikin-Fodulović, K. P., Zdunić, G. M., Popović, M. P. (2006) Essential oil of Seseli peucedanoides (MB) Kos.-Pol. J. Essent. Oil Res. 18, 286–287.
-
4.
Chebil, L., Humeau, C., Anthoni, J., Dehez, F., Engasser, J., Ghoul, M. (2007) Solubility of flavonoids in organic solvents. J. Chem. Eng. Data 52, 1552–1556.
-
5.
Ćurčić, M., Stanković, M. S., Radojević, I., Stefanović, O., Čomić, Lj., Topuzović, M., Djačić, D., Marković, S. (2012) Biological effects, total phenolic content and flavonoid concentrations of fragrant yellow onion (Allium flavum L.). Med. Chem. 8, 46–51.
-
6.
El-Agbar, Z., Shakya, A., Khalaf, N., Al-Haroon, M. (2008) Comparative antioxidant activity of some edible plants. Turk. J. Biol. 32, 193–196.
-
7.
Jakovljević, D., Stanković, M. S., Topuzović, M. (2013) Seasonal variability of Chelidonium majus L. secondary metabolites content and antioxidant activity. EXCLI J. 12, 260–268.
-
8.
Khan, S., Ullah, F., Mahmood, T. (2013) In vitro antimicrobial and cytotoxic activity of Tamarix dioica Roxb. leaves. Turk. J. Biol. 37, 329–335.
-
9.
Koksal, E., Bursal, E., Dikici, E., Tozoglu, F., Gulcin, I. (2011) Antioxidant activity of Melissa officinalis leaves. J. Med. Plant. Res. 5, 217–222.
-
10.
Kukula-Koch, W., Aligiannis, N., Halabalaki, M., Skaltsounis, A. L., Glowniak, K., Kalpoutzakis, E. (2013) Influence of extraction procedures on phenolic content and antioxidant activity of Cretan barberry herb. Food Chem. 138, 406–413.
-
11.
Kumarasamy, Y., Byres, M., Cox, P. J., Jasapars, M., Nahar, L., Sarker, S. D. (2007) Screening seeds of some Scottish plants for free-radical scavenging activity. Phytother. Res. 21, 615–621.
-
12.
Küpeli, E., Tosun, A., Yesilada, E. (2006) Anti-inflammatory and antinociceptive activities of Seseli L. species (Apiaceae) growing in Turkey. J. Ethnopharmacol. 104, 310–314.
-
13.
Lee, S. E., Hwang, H. J., Ha, J. S., Jeong, H. S., Kim, J. H. (2003) Screening of medicinal plant extracts for antioxidant activity. Life Sci. 73, 167–179.
-
14.
Marčetić, M. D., Lakušić, B. S., Lakušić, D. V., Kovačević, N. N. (2013) Variability of the root essential oils of Seseli rigidum Waldst. et Kit. (Apiaceae) from different populations in Serbia. Chem. Biodivers. 10, 1653–1666.
-
15.
Marčetić, M., Božić, D., Milenković, M., Lakušić, B., Kovačević, N. (2012) Chemical composition and antimicrobial activity of essential oil of different parts of Seseli rigidum. Nat. Prod. Commun. 7, 1091–1094.
-
16.
Matejić, J. S., Džamić, A. M., Mihajilov-Krstev, T., Ranđelović, V. N., Krivošej, Z. Đ., Marin, P. D. (2012) Total phenolic content, flavonoid concentration, antioxidant and antimicrobial activity of methanol extracts from three Seseli L. taxa. Centr. Eur. J. Biol. 7, 1116–1122.
-
17.
Milosavljević, S., Tešević, V., Vučković, I., Jadranin, M., Vajs, V., Soković, M., Janačković, P., Jovanović, A. (2007) Composition and antifungal activity of the essential oil of Seseli annuum wildgrowing in Serbia. Fitoterapia 78, 319–322.
-
18.
Nikolić, V. (1973) Seseli. In: Josifović, M. (ed.) Flora of Republic of Serbia. SANU, Belgrade. pp. 241–249.
-
19.
Ozturk, S., Ercisli, S. (2006) Chemical composition and in vitro antibacterial activity of Seseli libanotis. World J. Microb. Biot. 22, 261–265.
-
20.
Sarker, S. D., Nahar, L., Kumarasamy, Y. (2007) Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals. Methods 42, 321–324.
-
21.
Šiljegović, J., Glamočlija, J., Soković, M., Vučković, I., Tešević, V., Milosavljević, S., Stešević, D. (2011) Composition and antimicrobial activity of Seseli montanum subsp. tommasinii essential oil. N.P.C. 6, 263–266.
-
22.
Stanković, M. S., Nićiforović, N., Topuzović, M., Solujić, S. (2011) Total phenolic content, flavonoid concentrations and antioxidant activity of the whole plant and plant parts extracts from Teucrium montanum L. var. montanum, f. supinum (L.) Reichenb. Biotechnol. Biotec. Eq. 25, 2222–2227.
-
23.
Stojković, S., Petrović, S., Kukić, J., Džamić, A., Ristić, M., Milenković, M., Glamočlija, J., Soković, M., Stojković, D. (2009) Chemical composition and antimicrobial and antioxidant activity of Seseli rigidum flower essential oil. Chem. Nat. Comp. 45, 253–256.
-
24.
Sultana, B., Anwar, F., Ashraf, M. (2009) Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Molecules 14, 2167–2180.
-
25.
Tosun, A., Kürkçüoglu, M., Dogan, E., Duman, H., Başer, K. H. C. (2006) Essential oil composition of Seseli petraeum M. Bieb. and Seseli andronakii Woron. growing in Turkey. Flavour Frag. J. 21, 257–259.
-
26.
Turkoglu, S., Turkoglu, I., Kahyaoglu M., Celık, S. (2010) Determination of antimicrobial and antioxidant activities of Turkish endemic Ajuga chamaepitys (L.) Schreber subsp. euphratica P.H. Davis (Lamiaceae). J. Med. Plant. Res. 4, 1260–1268.
-
27.
Wink, M. (2012) Medicinal plants: a source of anti-parasitic secondary metabolites. Molecules 17, 12771–12791.
Acta Biologica Hungarica
P.O. Box 35
H-8237 Tihany, Hungary
Phone: (36 87) 448 244 ext. 103
Fax: (36 87) 448 006
E-mail: elekes@tres.blki.hu
Indexing and Abstracting Services:
- Biological Abstracts
- BIOSIS Previews
- CAB Abstracts
- Chemical Abstracts
- Current Contents: Agriculture
- Biology and Environmental Sciences
- Elsevier BIOBASE
- Global Health
- Index Medicus
- Index Veterinarius
- Medline
- Referativnyi Zhurnal
- Science Citation Index
- Science Citation Index Expanded (SciSearch)
- SCOPUS
- The ISI Alerting Services
- Zoological Abstracts
| Acta Biologica Hungarica | |
|---|---|
| Language | English |
| Size | |
| Year of Foundation |
1950 |
| Publication Programme |
changed title |
| Volumes per Year |
|
| Issues per Year |
|
| Founder | Magyar Tudományos Akadémia |
| Founder's Address |
H-1051 Budapest, Hungary, Széchenyi István tér 9. |
| Publisher | Akadémiai Kiadó |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 0236-5383 (Print) |
| ISSN | 1588-256X (Online) |
Monthly Content Usage
| Abstract Views | Full Text Views | PDF Downloads | |
|---|---|---|---|
| Dec 2024 | 20 | 0 | 0 |
| Jan 2025 | 28 | 0 | 0 |
| Feb 2025 | 53 | 0 | 0 |
| Mar 2025 | 38 | 0 | 0 |
| Apr 2025 | 34 | 0 | 0 |
| May 2025 | 7 | 0 | 0 |
| Jun 2025 | 0 | 0 | 0 |
Copyright Akadémiai Kiadó AKJournals is the trademark of Akadémiai Kiadó's journal publishing business branch.
Powered by PubFactory