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  • 1 Microbiological Research Group, Hungarian Academy of Sciences and University of Szeged P.O. Box 533, H-6701 Szeged, Hungary
  • | 2 Microbiological Research Group, Hungarian Academy of Sciences and University of Szeged P.O. Box 533, H-6701 Szeged, Hungary
  • | 3 Department of Microbiology, Faculty of Sciences, University of Szeged P.O. Box 533, H-6701 Szeged, Hungary
  • | 4 Department of Microbiology, Faculty of Sciences, University of Szeged P.O. Box 533, H-6701 Szeged, Hungary
  • | 5 2Department of Microbiology, Faculty of Sciences, University of Szeged P.O. Box 533, H-6701 Szeged, Hungary
  • | 6 Department of Microbiology, Faculty of Sciences, University of Szeged P.O. Box 533, H-6701 Szeged, Hungary
  • | 7 HAS-USZ Microbiology Research Group, Department of Microbiology, University of Szeged Department of Clinical Microbiology P.O. Box 533, H-6701 Szeged, Hungary
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Cellulolytic, xylanolytic, chitinolytic and b-1,3-glucanolytic enzyme systems of species belonging to the filamentous fungal genus Trichoderma have been investigated in details and are well characterised. The ability of Trichoderma strains to produce extracellular proteases has also been known for a long time, however, the proteolytic enzyme system is relatively unknown in this genus. Fortunately, in the recent years more and more attention is focused on the research in this field. The role of Trichoderma proteases in the biological control of plant pathogenic fungi and nematodes has been demonstrated, and it is also suspected that they may be important for the competitive saprophytic ability of green mould isolates and may represent potential virulence factors of Trichoderma strains as emerging fungal pathogens of clinical importance. The aim of this review is to summarize the information available about the extracellular proteases of Trichoderma. Numerous studies are available about the extracellular proteolytic enzyme profiles of Trichoderma strains and about the effect of abiotic environmental factors on protease activities. A number of protease enzymes have been purified to homogeneity and some protease encoding genes have been cloned and characterized. These results will be reviewed and the role of Trichoderma proteases in biological control as well as their advantages and disadvantages in biotechnology will be discussed.

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