Acta Microbiologica et Immunologica Hungarica
Volume/Issue:
Volume 53: Issue 2
Disturbance of Human Immunohomeostasis by Environmental Pollution and Alcohol Consumption
Authors: Birute Kazbariene 1 , Aurelija Krikstaponiene 2 , and Elena Monceviciute-Eringiene 3
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  • 1 Institute of Oncology, Vilnius University Santariskiu 1, LT-08660 Vilnius, Lithuania
  • 2 Institute of Oncology, Vilnius University Santariskiu 1, LT-08660 Vilnius, Lithuania
  • 3 Institute of Oncology, Vilnius University Santariskiu 1, LT-08660 Vilnius, Lithuania
DOI:
https://doi.org/10.1556/amicr.53.2006.2.7
Page Count:
209–218
Publication Date:
01 Jun 2006
Online Publication Date:
20 Jul 2006
Article Category:
Research Article
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Environmental pollution and consumption of alcohol evoke various immunomodulations promoting the progress of different pathologies. The purpose of this study was to evaluate the influence of alcohol consumption intensity on the immune system functions of humans living in ecologically different regions, i.e. in a district polluted with industrial siftings (Trakai, n=270) and in a relatively clean district (Širvintos, n=250). In the Trakai cohort 96% and in Širvintos group 89% of persons consumed alcohol. With regard to alcohol consumption habits the immunohaematological indices were investigated in the following four groups: abstinents, light alcohol users, moderate alcohol users and alcohol abusers. We determined the compensatory mechanisms of immune system functions of moderate alcohol users and alcohol abusers in comparison with abstinents in the relatively clean Širvintos district. In the Trakai district polluted with industrial siftings such compensatory reactions where not found. Thus, damage to the immune system functions is not only an endogenous risk factor for many diseases, but also an indicator of organism injury. This investigation stated, that immunity disturbance in humans depends on alcohol consumption intensity and place of residence.

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Cover Acta Microbiologica et Immunologica Hungarica
Acta Microbiologica et Immunologica Hungarica A Quarterly of the Hungarian Academy of Sciences
Print ISSN:
1217-8950
Online ISSN:
1588-2640
Keywords:
alcohol consumption intensity; environmental contamination; immunity

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