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  • 1 University of North Bengal Department of Biotechnology, Microbial Biotechnology Laboratory Raja Rammohunpur Siliguri 734013 West Bengal India
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Plasmid content was investigated in hundred copiotrophic Gram-negative river water isolates that exhibited resistance to four or more antibiotics. A total of seventy-seven isolates were found to carry plasmids of varying sizes. These isolates were primarily grouped as Pseudomonads and members of Enterobacteriaceae on the basis of physiological and biochemical tests. Fifty-six isolates that were rifampicin-sensitive and belonged to Enterobacteriaceae family were chosen as donors for the conjugal transfer assay. Eighteen of the isolates successfully transferred conjugable plasmids to the E. coli DH5 α recipient. Countable multiple antibiotic resistant transconjugants arose readily and conjugal transfer frequency was in the range of 3.75 × 10 −6 to 1.0 × 10 −1 . The most common carriage of resistances conferred by transmissible R plasmids was against ampicillin, cefotaxim and cephalexin. The residence of class 1 integrons on conjugative R plasmids was confirmed in only six transconjugants. Gene cassettes borne on the integrons were identified to be dihydrofolate reductases (dhfrs) . The major concern of this study was about the copiotrophs containing self-transmissible R plasmids which may be potential reservoirs of antibiotic-resistance genes and instrumental in dissemination of the same in the environment.

  • Armstrong, J., Shigeno, D. S., Calomiris, J. J., Seidler, R. J.: Antibiotic-resistant bacteria in drinking water. Appl Environ Microbiol 42 , 277–283 (1981).

    Seidler R. J. , 'Antibiotic-resistant bacteria in drinking water ' (1981 ) 42 Appl Environ Microbiol : 277 -283.

    • Search Google Scholar
  • Ash, R. J., Mauck, B., Morgan, M.: Antibiotic resistance of gram-negative bacteria in rivers, United States. Emerg Infect Dis 8 , 713–716 (2002).

    Morgan M. , 'Antibiotic resistance of gram-negative bacteria in rivers, United States ' (2002 ) 8 Emerg Infect Dis : 713 -716.

    • Search Google Scholar
  • Bedenic, B., Randegger, C. C., Stobberingh, E., Hachler, H.: Molecular epidemiology of extended-spectrum beta-lactamases from Klebsiella pneumoniae strains isolated in Zagreb, Croatia. Eur J Clin Microbiol Infect Dis 20 , 505–508 (2001).

    Hachler H. , 'Molecular epidemiology of extended-spectrum beta-lactamases from Klebsiella pneumoniae strains isolated in Zagreb, Croatia ' (2001 ) 20 Eur J Clin Microbiol Infect Dis : 505 -508.

    • Search Google Scholar
  • Bhadra, B., Mukherjee, S., Chakraborty, R., Nanda, A. K.: Physicochemical and bacteriological investigation on the river Torsa of North Bengal. J Environ Biol 24 , 125–133 (2003).

    Nanda A. K. , 'Physicochemical and bacteriological investigation on the river Torsa of North Bengal ' (2003 ) 24 J Environ Biol : 125 -133.

    • Search Google Scholar
  • Birnboim, H. C., Doly, J.: A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acid Res 7 , 1513–1523 (1979).

    Doly J. , 'A rapid alkaline extraction procedure for screening recombinant plasmid DNA ' (1979 ) 7 Nucleic Acid Res : 1513 -1523.

    • Search Google Scholar
  • Biyela, P. T., Lin, J., Bezuidenhout, C. C.: The role of aquatic ecosystems as reservoirs of antibiotic resistant bacteria and antibiotic resistance genes. Water Sci Technol 50 , 45–50 (2004).

    Bezuidenhout C. C. , 'The role of aquatic ecosystems as reservoirs of antibiotic resistant bacteria and antibiotic resistance genes ' (2004 ) 50 Water Sci Technol : 45 -50.

    • Search Google Scholar
  • Blondeau, J. M., Tillotson, G. S.: Antimicrobial susceptibility patterns of respiratory pathogens-a global perspective. Semin Respir Infect 15 , 195–207 (2000).

    Tillotson G. S. , 'Antimicrobial susceptibility patterns of respiratory pathogens-a global perspective ' (2000 ) 15 Semin Respir Infect : 195 -207.

    • Search Google Scholar
  • Boon, P. I., Cattanach, M.: Antibiotic resistance of native and fecal bacteria isolated from rivers, reservoirs and sewage treatment facilities in Victoria, south-eastern Australia. Lett Appl Microbiol 28 , 164–168 (1999).

    Cattanach M. , 'Antibiotic resistance of native and fecal bacteria isolated from rivers, reservoirs and sewage treatment facilities in Victoria, south-eastern Australia ' (1999 ) 28 Lett Appl Microbiol : 164 -168.

    • Search Google Scholar
  • Cernat, R., Lazar, V., Balotescu, C., Cotar, A., Coipan, E., Cojocaru, C.: Distribution and diversity of conjugative plasmids among some multiple antibiotic resistant E. coli strains isolated from river waters. Bacteriol Virusol Parazitol Epidemiol 47 , 147–153 (2002).

    Cojocaru C. , 'Distribution and diversity of conjugative plasmids among some multiple antibiotic resistant E. coli strains isolated from river waters ' (2002 ) 47 Bacteriol Virusol Parazitol Epidemiol : 147 -153.

    • Search Google Scholar
  • Chang, B. J., Bolton, S. M.: Plasmids and resistance to antimicrobial agents in Aeromonas sobria and Aeromonas hydrophila clinical isolates. Antimicrob Agents Chemother 31 , 1281–1282 (1987).

    Bolton S. M. , 'Plasmids and resistance to antimicrobial agents in Aeromonas sobria and Aeromonas hydrophila clinical isolates ' (1987 ) 31 Antimicrob Agents Chemother : 1281 -1282.

    • Search Google Scholar
  • Chang, C. Y., Chang, L. L., Chang, Y. H., Lee, T. M., Chang, S. F.: Characterisation of drug resistance gene cassettes associated with class 1 integrons in clinical isolates of Escherichia coli from Taiwan, ROC. J Med Microbiol 49 , 1097–1102 (2000).

    Chang S. F. , 'Characterisation of drug resistance gene cassettes associated with class 1 integrons in clinical isolates of Escherichia coli from Taiwan, ROC ' (2000 ) 49 J Med Microbiol : 1097 -1102.

    • Search Google Scholar
  • Chaurasia, S.: Water pollution from mass bathing in river Mandakini during Chitrakoot Deepawali Mela 1993. Indian J Environ Prot 14 , 758–765 (1994).

    Chaurasia S. , 'Water pollution from mass bathing in river Mandakini during Chitrakoot Deepawali Mela 1993 ' (1994 ) 14 Indian J Environ Prot : 758 -765.

    • Search Google Scholar
  • Chen, S., Zhao, S., White, D. G., Shroeder, C. M., Lu, R., Yang, H., McDermott, P. F., Ayers, S., Meng, J.: Characterization of multiple-antimicrobial-resistant Salmonella serovars isolated from retail meats. Appl Environ Microbiol 70 , 1–7 (2004).

    Meng J. , 'Characterization of multiple-antimicrobial-resistant Salmonella serovars isolated from retail meats ' (2004 ) 70 Appl Environ Microbiol : 1 -7.

    • Search Google Scholar
  • Davison, J.: Genetic exchange between bacteria in the environment. Plasmid 42 , 73–91 (1999).

    Davison J. , 'Genetic exchange between bacteria in the environment ' (1999 ) 42 Plasmid : 73 -91.

    • Search Google Scholar
  • Fluit, A. C., Wielders, C. L., Verhoef, J., Schmitz, F. J.: Epidemiology and susceptibility of 3,051 Staphylococcus aureus isolates from 25 university hospitals participating in the European SENTRY study. J Clin Microbiol 39 , 3727–3732 (2001).

    Schmitz F. J. , 'Epidemiology and susceptibility of 3,051 Staphylococcus aureus isolates from 25 university hospitals participating in the European SENTRY study ' (2001 ) 39 J Clin Microbiol : 3727 -3732.

    • Search Google Scholar
  • Fluit, A. C., Schmitz, F.-J.: Resistance integrons and super integrons. Clin Microbiol Infect 10 , 272–288 (2004).

    Schmitz F.-J. , 'Resistance integrons and super integrons ' (2004 ) 10 Clin Microbiol Infect : 272 -288.

    • Search Google Scholar
  • Girlich, D., Poirel, L., Leelaporn, A., Karim, A., Tribuddharat, C.: Molecular epidemiology of the integron-located VEB-1 extended spectrum beta-lactamase in nosocomial enterobacterial isolates in Bangkok, Thailand. J Clin Microbiol 39 , 175–182 (2001).

    Tribuddharat C. , 'Molecular epidemiology of the integron-located VEB-1 extended spectrum beta-lactamase in nosocomial enterobacterial isolates in Bangkok, Thailand ' (2001 ) 39 J Clin Microbiol : 175 -182.

    • Search Google Scholar
  • Goni-Urizza, M., Capdepuy, M., Arpin, C., Raymond, N., Caumette, P., Quentin, C.: Impact of an urban effluent on antibiotic resistance of riverine Enterobacteriaceae and Aeromonas spp. Appl Environ Microbiol 66 , 125–132 (2000).

    Quentin C. , 'Impact of an urban effluent on antibiotic resistance of riverine Enterobacteriaceae and Aeromonas spp ' (2000 ) 66 Appl Environ Microbiol : 125 -132.

    • Search Google Scholar
  • Gotz, A., Pukall, R., Smit, E., Tietze, E., Prager, R., Tschape, H., van Elsas, J. D., Smalla, K.: Detection and characterization of broad-host-range plasmids in environmental bacteria by PCR. Appl Environ Microbiol 62 , 2621–2628 (1996).

    Smalla K. , 'Detection and characterization of broad-host-range plasmids in environmental bacteria by PCR ' (1996 ) 62 Appl Environ Microbiol : 2621 -2628.

    • Search Google Scholar
  • Harbarth, S., Albrich, W., Goldmann, D. A., Huebner, J.: Control of multiply resistant cocci: do international comparisons help? Lancet Infect Dis 1 , 251–261 (2001).

    Huebner J. , 'Control of multiply resistant cocci: do international comparisons help? ' (2001 ) 1 Lancet Infect Dis : 251 -261.

    • Search Google Scholar
  • Hinnebusch, B. J., Rosso, M. L., Schwan, T. G., Carniel, E.: High frequency conjugative transfer of antibiotic resistance genes to Yersinia pestis in the flea midgut. Mol Microbiol 46 , 349–354 (2002).

    Carniel E. , 'High frequency conjugative transfer of antibiotic resistance genes to Yersinia pestis in the flea midgut ' (2002 ) 46 Mol Microbiol : 349 -354.

    • Search Google Scholar
  • Hsu, C. H., Hwang, S. C., Liu, J. K.: Succession of bacterial drug resistance as an indicator of antibiotic application in aquaculture. J Fish Soc Taiwan 19 , 55–64 (1992).

    Liu J. K. , 'Succession of bacterial drug resistance as an indicator of antibiotic application in aquaculture ' (1992 ) 19 J Fish Soc Taiwan : 55 -64.

    • Search Google Scholar
  • Kelch, W. J., Lee, J. S.: Antibiotic resistance patterns of gram negative bacteria isolated from environmental sources. Appl Environ Microbiol 36 , 450–456 (1978).

    Lee J. S. , 'Antibiotic resistance patterns of gram negative bacteria isolated from environmental sources ' (1978 ) 36 Appl Environ Microbiol : 450 -456.

    • Search Google Scholar
  • Kruse, H., Sorum, H.: Transfer of multiple drug resistance plasmids between bacteria of diverse origins in natural microenvironments. Appl Environ Microbiol 60 , 4015–4021 (1994).

    Sorum H. , 'Transfer of multiple drug resistance plasmids between bacteria of diverse origins in natural microenvironments ' (1994 ) 60 Appl Environ Microbiol : 4015 -4021.

    • Search Google Scholar
  • Leverstein van Hall, M. A., Box, A. T. A., Blok, H. E. M., Paauw, A., Fluit, A. C., Verhoef, J.: Evidence of extensive interspecies transfer of integron-mediated antimicrobial resistance genes among multidrug-resistant enterobacteriaceae in a clinical setting. J Infect Dis 186 , 49–56 (2002).

    Verhoef J. , 'Evidence of extensive interspecies transfer of integron-mediated antimicrobial resistance genes among multidrug-resistant enterobacteriaceae in a clinical setting ' (2002 ) 186 J Infect Dis : 49 -56.

    • Search Google Scholar
  • Leverstein-van Hall, M. A., Blok, H. E. M., Donders, A. R., Paauw, A., Fluit, A. C., Verhoef, J.: Multidrug resistance among enterobacteriaceae is strongly associated with the presence of integrons and is independent of species and isolate origin. J Infect Dis 187 , 251–259 (2003).

    Verhoef J. , 'Multidrug resistance among enterobacteriaceae is strongly associated with the presence of integrons and is independent of species and isolate origin ' (2003 ) 187 J Infect Dis : 251 -259.

    • Search Google Scholar
  • Lin, J., Biyela, P. T., Puckree, T.: Antibiotic resistance profiles of environmental isolates from Mhlathuze River, KwaZulu Natal (RSA). Water SA 30 , 23–28 (2004).

    Puckree T. , 'Antibiotic resistance profiles of environmental isolates from Mhlathuze River, KwaZulu Natal (RSA) ' (2004 ) 30 Water SA : 23 -28.

    • Search Google Scholar
  • Marcinek, H., Wirth, R., Muscholl-Silberhorn, A., Gauer, M.: Enterococcus faecalis gene transfer under natural conditions in municipal sewage water treatment plants. Appl Environ Microbiol 64 , 626–632 (1998).

    Gauer M. , 'Enterococcus faecalis gene transfer under natural conditions in municipal sewage water treatment plants ' (1998 ) 64 Appl Environ Microbiol : 626 -632.

    • Search Google Scholar
  • Mukherjee, S., Bhadra, B., Chakraborty, R., Gurung, A., Some, S., Chakraborty, R.: Unregulated use of antibiotics in Siliguri city vis-à-vis occurrence of MAR bacteria in community waste water and river Mahananda, and their potential for resistance gene transfer. J Environ Biol 26 , 229–238 (2005).

    Chakraborty R. , 'Unregulated use of antibiotics in Siliguri city vis-à-vis occurrence of MAR bacteria in community waste water and river Mahananda, and their potential for resistance gene transfer ' (2005 ) 26 J Environ Biol : 229 -238.

    • Search Google Scholar
  • Mukherjee, S., Chakraborty, R.: Incidence of class 1 integrons in multiple antibiotic-resistant Gram-negative bacteria from the River Torsa in India. Res Microbiol 157 , 220–226 (2006).

    Chakraborty R. , 'Incidence of class 1 integrons in multiple antibiotic-resistant Gram-negative bacteria from the River Torsa in India ' (2006 ) 157 Res Microbiol : 220 -226.

    • Search Google Scholar
  • Pathak, S. P., Kumar, S., Ramteke, P. W., Murthy, R. C., Singh, K. P., Bhattacharjee, J. W., Ray, P. K.: Riverine pollution in some northern and north eastern states in India. Environ Monitor Ass 22 , 227–236 (1992).

    Ray P. K. , 'Riverine pollution in some northern and north eastern states in India ' (1992 ) 22 Environ Monitor Ass : 227 -236.

    • Search Google Scholar
  • Rowe-Magnus, D. A., Mazel, D.: Resistance gene capture. Curr Opinion Microbiol 2 , 483–488 (1999).

    Mazel D. , 'Resistance gene capture ' (1999 ) 2 Curr Opinion Microbiol : 483 -488.

  • Rudneva, S. N., Stoliarova, L. G., Ershov, A. A., Pantiukhova, V. V.: Spread and transfer of plasmid resistance in Escherichia coli . Antibiotiki 25 , 429–432 (1980).

    Pantiukhova V. V. , 'Spread and transfer of plasmid resistance in Escherichia coli ' (1980 ) 25 Antibiotiki : 429 -432.

    • Search Google Scholar
  • Salyers, A. A., Amiable-Cuevas, C. F.: Why are antibiotic resistance genes so resistant to elimination? Antimicrob Agents Chemother 41 , 2321–2325 (1997).

    Amiable-Cuevas C. F. , 'Why are antibiotic resistance genes so resistant to elimination? ' (1997 ) 41 Antimicrob Agents Chemother : 2321 -2325.

    • Search Google Scholar
  • Son, R., Rusul, G., Karim, M. I. A.: Conjugal transfer of plasmids and antibiotic resistance among Escherichia coli isolated from animals in a rural area in Sarawak (Malaysia). J Appl Microbiol 82 , 240–244 (1997).

    Karim M. I. A. , 'Conjugal transfer of plasmids and antibiotic resistance among Escherichia coli isolated from animals in a rural area in Sarawak (Malaysia) ' (1997 ) 82 J Appl Microbiol : 240 -244.

    • Search Google Scholar
  • Thungapathra, M., Amita, Sinha, K. K., Ray Chaudhuri, S., Garg, P., Ramamurthy, T., Nair, G. B., Ghosh, A.: Occurrence of antibiotic resistance gene cassettes aac (6′)- Ib , dfr A5, dfr A12 , and ereA2 in class I integrons in Non-O1, Non-O139 Vibrio cholerae strains in India. Antimicrob Agents Chemother 46 , 2948–2955 (2002).

    Ghosh A. , 'Occurrence of antibiotic resistance gene cassettes aac(6′)-Ib, dfr A5, dfr A12, and ereA2 in class I integrons in Non-O1, Non-O139 Vibrio cholerae strains in India ' (2002 ) 46 Antimicrob Agents Chemother : 2948 -2955.

    • Search Google Scholar
  • Voss, A., Milatovic, D., Wallrauch-Schwarz, C., Rosdahl, V. T., Braveny, I.: Methicillin-resistant Staphylococcus aureus in Europe. Eur J Clin Microbiol Infect Dis 13 , 50–55 (1994).

    Braveny I. , 'Methicillin-resistant Staphylococcus aureus in Europe ' (1994 ) 13 Eur J Clin Microbiol Infect Dis : 50 -55.

    • Search Google Scholar
  • Walia, S. K., Kaiser, A., Parkash, M., Chaudhury, G. R.: Self-transmissible antibiotic resistance to ampicillin, streptomycin, and tetracycline found in Escherichia coli isolates from contaminated drinking water. J Environ Sci Health A. Tox Hazard Subst Environ Eng 39 , 651–662 (2004).

    Chaudhury G. R. , 'Self-transmissible antibiotic resistance to ampicillin, streptomycin, and tetracycline found in Escherichia coli isolates from contaminated drinking water ' (2004 ) 39 J Environ Sci Health A. Tox Hazard Subst Environ Eng : 651 -662.

    • Search Google Scholar
  • White, P. A., McIver, C. J., Rawlinson, W. D.: Integrons and gene cassettes in the enterobacteriaceae. Antimicrob Agents Chemother 45 , 2658–2661 (2001).

    Rawlinson W. D. , 'Integrons and gene cassettes in the enterobacteriaceae ' (2001 ) 45 Antimicrob Agents Chemother : 2658 -2661.

    • Search Google Scholar
  • Yates, C. M., Pearce, N. C., Woolhouse, M. E. J., Amyes, S. G. B.: High frequency transfer and horizontal spread of apramycin resistance in calf fecal Escherichia coli . J Antimicrob Chemother 54 , 534–537 (2004).

    Amyes S. G. B. , 'High frequency transfer and horizontal spread of apramycin resistance in calf fecal Escherichia coli ' (2004 ) 54 J Antimicrob Chemother : 534 -537.

    • Search Google Scholar
  • Yu, H. S., Lee, J. C., Kang, H. Y., Jeong, Y. S., Lee, E. Y., Choi, C. H., Tae, S. H., Lee, Y. C., Seol, S. Y., Cho, D. T.: Prevalence of dfr genes associated with integron and dissemination of dfrA17 among urinary isolates of Escherichia coli in Korea. J Antimicrob Chemother 53 , 445–450 (2004).

    Cho D. T. , 'Prevalence of dfr genes associated with integron and dissemination of dfrA17 among urinary isolates of Escherichia coli in Korea ' (2004 ) 53 J Antimicrob Chemother : 445 -450.

    • Search Google Scholar

 

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Senior editors

Editor-in-Chief: Prof. Dóra Szabó (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Managing Editor: Dr. Béla Kocsis (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Co-editor: Dr. Andrea Horváth (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Editorial Board

  • Prof. Éva ÁDÁM (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Sebastian AMYES (Department of Medical Microbiology, University of Edinburgh, Edinburgh, UK.)
  • Dr. Katalin BURIÁN (Institute of Clinical Microbiology University of Szeged, Szeged, Hungary; Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary.)
  • Dr. Orsolya DOBAY (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Ildikó Rita DUNAY (Institute of Inflammation and Neurodegeneration, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany; Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany)
  • Prof. Levente EMŐDY(Department of Medical Microbiology and Immunology, University of Pécs, Pécs, Hungary.)
  • Prof. Anna ERDEI (Department of Immunology, Eötvös Loránd University, Budapest, Hungary, MTA-ELTE Immunology Research Group, Eötvös Loránd University, Budapest, Hungary.)
  • Prof. Éva Mária FENYŐ (Division of Medical Microbiology, University of Lund, Lund, Sweden)
  • Prof. László FODOR (Department of Microbiology and Infectious Diseases, University of Veterinary Medicine, Budapest, Hungary)
  • Prof. József KÓNYA (Department of Medical Microbiology, University of Debrecen, Debrecen, Hungary)
  • Prof. Yvette MÁNDI (Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary)
  • Prof. Károly MÁRIALIGETI (Department of Microbiology, Eötvös Loránd University, Budapest, Hungary)
  • Prof. János MINÁROVITS (Department of Oral Biology and Experimental Dental Research, University of Szeged, Szeged, Hungary)
  • Prof. Béla NAGY (Centre for Agricultural Research, Institute for Veterinary Medical Research, Budapest, Hungary.)
  • Prof. István NÁSZ (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Kristóf NÉKÁM (Hospital of the Hospitaller Brothers in Buda, Budapest, Hungary.)
  • Dr. Eszter OSTORHÁZI (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Rozália PUSZTAI (Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary)
  • Prof. Peter L. RÁDY (Department of Dermatology, University of Texas, Houston, Texas, USA)
  • Prof. Éva RAJNAVÖLGYI (Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary)
  • Prof. Ferenc ROZGONYI (Institute of Laboratory Medicine, Semmelweis University, Budapest, Hungary)
  • Prof. Zsuzsanna SCHAFF (2nd Department of Pathology, Semmelweis University, Budapest, Hungary)
  • Prof. Joseph G. SINKOVICS (The Cancer Institute, St. Joseph’s Hospital, Tampa, Florida, USA)
  • Prof. Júlia SZEKERES (Department of Medical Biology, University of Pécs, Pécs, Hungary.)
  • Prof. Mária TAKÁCS (National Reference Laboratory for Viral Zoonoses, National Public Health Center, Budapest, Hungary.)
  • Prof. Edit URBÁN (Department of Medical Microbiology and Immunology University of Pécs, Pécs, Hungary; Institute of Translational Medicine, University of Pécs, Pécs, Hungary.)

 

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2020  
Total Cites 662
WoS
Journal
Impact Factor
2,048
Rank by Immunology 145/162(Q4)
Impact Factor Microbiology 118/137 (Q4)
Impact Factor 1,904
without
Journal Self Cites
5 Year 0,671
Impact Factor
Journal  0,38
Citation Indicator  
Rank by Journal  Immunology 146/174 (Q4)
Citation Indicator  Microbiology 120/142 (Q4)
Citable 42
Items
Total 40
Articles
Total 2
Reviews
Scimago 28
H-index
Scimago 0,439
Journal Rank
Scimago Immunology and Microbiology (miscellaneous) Q4
Quartile Score Medicine (miscellaneous) Q3
Scopus 438/167=2,6
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Scopus General Immunology and Microbiology 31/45 (Q3)
Scite Score Rank  
Scopus 0,760
SNIP
Days from  225
submission
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Days from  118
acceptance
to publication
Acceptance 19%
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2019  
Total Cites
WoS
485
Impact Factor 1,086
Impact Factor
without
Journal Self Cites
0,864
5 Year
Impact Factor
1,233
Immediacy
Index
0,286
Citable
Items
42
Total
Articles
40
Total
Reviews
2
Cited
Half-Life
5,8
Citing
Half-Life
7,7
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0,00059
Article Influence
Score
0,246
% Articles
in
Citable Items
95,24
Normalized
Eigenfactor
0,07317
Average
IF
Percentile
7,690
Scimago
H-index
27
Scimago
Journal Rank
0,352
Scopus
Scite Score
320/161=2
Scopus
Scite Score Rank
General Immunology and Microbiology 35/45 (Q4)
Scopus
SNIP
0,492
Acceptance
Rate
16%

 

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Acta Microbiologica et Immunologica Hungarica
Language English
Size A4
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Foundation
1954
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per Year
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Issues
per Year
4
Founder Magyar Tudományos Akadémia
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Address
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ISSN 1217-8950 (Print)
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