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  • 1 University of Medicine and Pharmacy Department of Microbiology Gh. Marinescu 38 540139 Tg. Mures Romania
  • | 2 Mures County University Hospital Clinical Microbiology Tg. Mures Romania
  • | 3 University of Szeged Institute of Clinical Microbiology, Faculty of Medicine Szeged Hungary
  • | 4 University of Medicine and Pharmacy Department of Epidemiology Tg. Mures Romania
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Our aim was to estimate the frequency and characteristics of methicillin-resistant Staphylococcus aureus (MRSA) strains occurring in a Romanian teaching hospital. We retrospectively studied isolates from infected or colonized patients treated at the intensive care and surgical units during January 2004-December 2005. The antibiotic susceptibility of MRSA strains and the presence of mecA gene were determined. Consecutively occurring strains isolated through a three-month period were typed using pulsed field gel electrophoresis. A total of 423 S. aureus strains were identified, methicillin-resistance was detected in 211 (49.9%) strains. Most of them were multiresistant. One of the MRSA genotypes identified by PFGE was commonly recovered from patients treated in the intensive care unit. According to our results. MRSA strains were frequently isolated pathogens in our hospital and there is an urgent need to enhance infection control efforts.

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