View More View Less
  • 1 Semmelweis University Department of Conservative Dentistry and Endodontics Szentkirályi u. 47 H-1088 Budapest Hungary
  • | 2 Semmelweis University Institute of Medical Microbiology Nagyvárad tér 4 H-1089 Budapest Hungary
  • | 3 Semmelweis University Department of Pedodontics and Orthodontics Szentkirályi u. 47 H-1088 Budapest Hungary
Restricted access

Purchase article

USD  $25.00

1 year subscription (Individual Only)

USD  $784.00

A study was conducted to compare the DNA structure of Streptococcus mutans strains in children with caries-active, caries-free, and gingivitis clinical diagnosis. Twenty-eight Streptococcus mutans strains from 100 children’s plaques were examined by pulsed-field gel electrophoresis (PFGE) method. The classified strains were closely related to one another, though the strains originated from different disease groups. Three identical pairs were found, but the pairs in two cases belonged to different disease groups.The results of the PFGE experiments suggest that there is no correlation between the different DNA patterns of S. mutans strains and their cariogenecity. So the different DNA strains of S. mutans are not the only determining factor in the development of dental caries.

  • Harris, N. O., Garcia-Godoy, F.: Primary Preventive Dentistry. Appleton&Lange, Standford, Connecticut 5 th ed. pp. 26–33 (1999).

  • Edelstein, B., Tinanoff, N.: Screening preschool children for dental caries using a microbial test. Pediatr Dent 11 , 129–132 (1989).

    Tinanoff N. , 'Screening preschool children for dental caries using a microbial test ' (1989 ) 11 Pediatr Dent : 129 -132.

    • Search Google Scholar
  • Krasse, B., de Cárie, Risco: Um guia prático para avaliacao e controle. Sao Paolo: Quintessence (1986).

    Cárie R. , '', in Um guia prático para avaliacao e controle , (1986 ) -.

  • Kristofferson, K., Gröndahl, H. G., Bratthall, D.: The more Streptococcus mutans , the more caries on approximal surfaces. J Dent Res 64 , 58–61 (1985).

    Bratthall D. , 'The more Streptococcus mutans, the more caries on approximal surfaces ' (1985 ) 64 J Dent Res : 58 -61.

    • Search Google Scholar
  • Llena-Puy, M. C., Montanana-Llorens, C., Forner-Navarro, L.: Cariogenic oral flora and its relation to dental caries. J Dent Child 67 , 42–46 (2000).

    Forner-Navarro L. , 'Cariogenic oral flora and its relation to dental caries ' (2000 ) 67 J Dent Child : 42 -46.

    • Search Google Scholar
  • Schlaenhauf, U., Rosendahl, R.: Clinical and microbiological caries-risk parameters at different stages of dental development. J Periodonti 61 , 141–143 (1990).

    Rosendahl R. , 'Clinical and microbiological caries-risk parameters at different stages of dental development ' (1990 ) 61 J Periodonti : 141 -143.

    • Search Google Scholar
  • World Health Organization: Oral Health Surveys: Basic Methods, 4 th edition, Geneva (1997).

  • Loesche, W. J., Rowan, J., Straffon, L. H., Loos, P. J.: Association of Streptococcus mutans with human detal decay. Infect Immun 11 , 1252–1260 (1975).

    Loos P. J. , 'Association of Streptococcus mutans with human detal decay ' (1975 ) 11 Infect Immun : 1252 -1260.

    • Search Google Scholar
  • Loesche, W. J., Straffon, L. H.: Longitudinal investigation the role of Streptococcus mutans in human fissure decay. Infect Immun 26 , 498–507 (1979).

    Straffon L. H. , 'Longitudinal investigation the role of Streptococcus mutans in human fissure decay ' (1979 ) 26 Infect Immun : 498 -507.

    • Search Google Scholar
  • Loesche, W. J.: Role of Streptococcus mutans in human dental decay. Microbiol Rev 50 , 353–380 (1986).

    Loesche W. J. , 'Role of Streptococcus mutans in human dental decay ' (1986 ) 50 Microbiol Rev : 353 -380.

    • Search Google Scholar
  • Loesche, W. J.: Antimicrobials in dentistry:with knowledge comes responsibility. J Dent Res 57 , 1432–1433 (1996).

    Loesche W. J. , 'Antimicrobials in dentistry:with knowledge comes responsibility ' (1996 ) 57 J Dent Res : 1432 -1433.

    • Search Google Scholar
  • Longo, P. L., Mattos-Graner, R. O., Mayer, M. P. A.: Determination of mutacin activity and detection of mutA genes in Streptococcus mutans genotypes from caries-free and caries-active children. Oral Microbiol Immunol 18 , 144–149 (2003).

    Mayer M. P. A. , 'Determination of mutacin activity and detection of mutA genes in Streptococcus mutans genotypes from caries-free and caries-active children ' (2003 ) 18 Oral Microbiol Immunol : 144 -149.

    • Search Google Scholar
  • Moss, J. S., Sarnat, H., Hector, M. P., Koch, G., Modeer, T., Peretz, B.: Insights into the Mouth. New Pathways to Prevention. United Kingdom, p. 27 (1999).

  • Köhler, B., Krasse, B.: Human strains of mutans streptococci show different cariogenic potential in the hamster model. Oral Microbial Immunol 5 , 177–180 (1990).

    Krasse B. , 'Human strains of mutans streptococci show different cariogenic potential in the hamster model ' (1990 ) 5 Oral Microbial Immunol : 177 -180.

    • Search Google Scholar
  • Caufield, P. W., Ratanapridakul, K., Allen, D. N., Cutter, G. R.: Plasmid-contaning strains of Streptococcus mutans cluster within family and racial cohorts: implications for natural transmission. Infect Immun 56 , 3216–3220 (1988).

    Cutter G. R. , 'Plasmid-contaning strains of Streptococcus mutans cluster within family and racial cohorts: implications for natural transmission ' (1988 ) 56 Infect Immun : 3216 -3220.

    • Search Google Scholar
  • Loe, H., Sillness, J.: Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odont Scand 21 , 533–551 (1963).

    Sillness J. , 'Periodontal disease in pregnancy. I. Prevalence and severity ' (1963 ) 21 Acta Odont Scand : 533 -551.

    • Search Google Scholar
  • Patterson, J. E., Kelly, C. C.: Pulsed-field gel electrophoresis as an epidemiologic tool for enterococci and streptococci. In: Fives-Taylor, P. M., Leblanc, D. J. (eds): Methods for Studying the Genetics, Molecular Biology, Physiology and Pathogenesis of the Streptococci. Dordrecht, the Netherlands: Kluwer Academic Publisher, pp. 233–239 (1998).

    Kelly C. C. , '', in Methods for Studying the Genetics, Molecular Biology, Physiology and Pathogenesis of the Streptococci , (1998 ) -.

  • Murchan, S., Kaufmann, M. E., Deplano, A., Cookson, B.: Harmonization of pulsed-field gel electrophoresis protocol for epidemiological typing of strains of methicillin-resistant Staphylococcus aureus: single approach developed by consensus in 10 European laboratories and its application for tracing the spread of related strains. J Clin Microbiol 41 , 15–85 (2003).

    Cookson B. , 'Harmonization of pulsed-field gel electrophoresis protocol for epidemiological typing of strains of methicillin-resistant Staphylococcus aureus: single approach developed by consensus in 10 European laboratories and its application for tracing the spread of related strains ' (2003 ) 41 J Clin Microbiol : 15 -85.

    • Search Google Scholar
  • Tenover, F. C., Arbeit, R. D., Goering, R. V., Swaminathan, B. et al.: Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: Criteria for bacterial strain typing. J Clinical Microbiology 33 , 2233–2239 (1995).

    Swaminathan B. , 'Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: Criteria for bacterial strain typing ' (1995 ) 33 J Clinical Microbiology : 2233 -2239.

    • Search Google Scholar
  • Li, Y, Caufield, P. W., Redmo, E. I., Thornqvist, E.: Differentiation of Streptococcus mutans and Streptococcus sobrinus via genotypic and phenotypic profiles from three different populations. Oral Microbiol Immunol 16 , 16–23 (2001).

    Thornqvist E. , 'Differentiation of Streptococcus mutans and Streptococcus sobrinus via genotypic and phenotypic profiles from three different populations ' (2001 ) 16 Oral Microbiol Immunol : 16 -23.

    • Search Google Scholar
  • Jordan, C., LeBlanc, D. J.: Influences of orthodontic appliances on oral populations of mutans streptococci. Oral Microbiol Immunol 17 , 65–71 (2002).

    LeBlanc D. J. , 'Influences of orthodontic appliances on oral populations of mutans streptococci ' (2002 ) 17 Oral Microbiol Immunol : 65 -71.

    • Search Google Scholar

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Jan 2021 9 0 0
Feb 2021 3 0 0
Mar 2021 10 0 0
Apr 2021 2 0 0
May 2021 9 0 0
Jun 2021 3 0 0
Jul 2021 0 0 0