Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disease, affecting phagocytic blood cells, which predispose patients to recurrent infectious complications. Herein, an 11-year-old girl is described who presented with liver abscess at the age of 9 years. Positive dihydrorhodamine (DHR) and nitrobluetetrazolium (NBT) tests confirmed the diagnosis of CGD for the patient. Anti-tuberculosis drugs and parenteral antibiotic therapy were started. Unusual visceral abscess and recurrent infections should be considered as an alarm for primary immunodeficiency diseases, while early diagnosis and appropriate treatment could prevent severe complications and even death in this group of patients.
Seger, R. A.: Modern management of chronic granulomatous disease. Br. J. Haematol. 140, 55–66 (2008).
Seger R. A., 'Modern management of chronic granulomatous disease' (2008) 140Br. J. Haematol.: 55-66.
Seger R. A.Modern management of chronic granulomatous diseaseBr. J. Haematol.20081405566)| false
Movahedi, M., Aghamohammadi, A., Rezaei, N. et al.: Chronic granulomatous disease: a clinical survey of 41 patients from the Iranian primary immunodeficiency registry. Int. Arch. Allergy Immunol. 134, 253–259 (2004).
Rezaei N., 'Chronic granulomatous disease: a clinical survey of 41 patients from the Iranian primary immunodeficiency registry' (2004) 134Int. Arch. Allergy Immunol.: 253-259.
Rezaei N.Chronic granulomatous disease: a clinical survey of 41 patients from the Iranian primary immunodeficiency registryInt. Arch. Allergy Immunol.2004134253259)| false