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  • 1 Bács-Kiskun County Teaching Hospital Department of Hospital Hygiene Kecskemét Hungary
  • | 2 Bács-Kiskun County Teaching Hospital Department of Pathology Kecskemét Hungary
  • | 3 Bács-Kiskun County Teaching Hospital Department of Oral and Maxillofacial Surgery and Otorhinolaryngology Kecskemét Hungary
  • | 4 Bács-Kiskun County Teaching Hospital Central Intensive Care Unit Kecskemét Hungary
  • | 5 Semmelweis University Clinical Microbiology Diagnostic Laboratory, Institute of Laboratory Medicine Budapest Hungary
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In polymorbid or anaemic patients who receive preoperative radiotherapy or undergo long duration surgery involving potentially infectious sites, perioperative antibiotic prophylaxis (PAP) that is effective against normal oral bacterial flora is mandatory and plays an important role in preventing postoperative infection. In a four-year retrospective analysis, the incidence, outcome, and the efficacy of PAP were evaluated in patients treated at the Department of Oral and Maxillofacial Surgery and Otorhinolaryngology at Kecskemét Hospital. The results were compared with data from the literature to determine if the use of PAP was adequate at the Department.During the study period (between 01/09/2007 and 31/01/2011) 108 patients were evaluated. The mean duration of prophylactic antibiotic treatment was 8.3 ± 5.2 days, with cefotaxime+metronidazole being the most commonly used combination. Surgical site infection occurred in 8 patients (7.5%) in the clean-contaminated category.Our results showed that the perioperative antibiotic prophylaxis administered at our Department was efficient and effective against the oral bacterial flora of patients. Its use is recommended in head and neck microsurgery. To avoid development of antibiotic resistance and to reduce costs, it seems that the duration of antibiotic regimen for primary surgery can be reduced from 8.3 ± 5.2 days to 3 days.

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