Among a wide range of cytokines, the Interleukin 12 (IL-12) family has its unique structural, functional, and immunological characteristics that have made this family as important immunological playmakers. Because of the importance of IL-12 heterodimeric cytokines in microbial infections, autoimmune diseases, and cancers, the authors of this literature discuss about the general characteristics of IL-12 family members, the interactions between IL-12 cytokines and pathogenic microorganisms, the interleukins receptors and their strategies for selecting different signalling pathways. IL-12 and IL-23 are similar in p40 subunits and both are involved in proinflammatory responses while, IL-27 and IL-35 contribute to anti-inflammatory activities; however, IL-27 is also involved in pro-inflammatory responses. There are some similarities and dissimilarities among IL-12 family members which make them a unique bridge between innate and adaptive immune systems. The bioactivities of IL-12 family indicate a brilliant promise for their applications in different fields of medicine. The members of IL-12 family are candidate for several therapeutics including gene therapy, cancer therapy, tumour therapy, and vaccination. To have an accurate diagnostic technique and definite treatment regarding to infectious diseases, the playmakers of IL-12 family as effective criteria together with microarray technology are the best choices for current and future applications.
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- Science Citation Index Expanded
| 2021 | |
|---|---|
| Web of Science | |
| Total Cites WoS |
696 |
| Journal Impact Factor | 2,298 |
| Rank by Impact Factor | Immunology 141/161 Microbiology 118/136 |
| Impact Factor without Journal Self Cites |
2,143 |
| 5 Year Impact Factor |
1,925 |
| Journal Citation Indicator | 0,39 |
| Rank by Journal Citation Indicator | Immunology 146/177 Microbiology 129/157 |
| Scimago | |
| Scimago H-index |
29 |
| Scimago Journal Rank |
0,362 |
| Scimago Quartile Score | Immunology and Microbiology (miscellaneous) (Q3) Medicine (miscellaneous) (Q3) |
| Scopus | |
| Scopus Cite Score |
3,6 |
| Scopus CIte Score Rank |
General Immunology and Microbiology 26/56 (Q2) Infectious Diseases 149/295 (Q3) Microbiology (medical) 66/118 (Q3) |
| Scopus SNIP |
0,598 |
| 2020 | |
| Total Cites | 662 |
| WoS | |
| Journal Impact Factor |
2,048 |
| Rank by | Immunology 145/162(Q4) |
| Impact Factor | Microbiology 118/137 (Q4) |
| Impact Factor | 1,904 |
| without | |
| Journal Self Cites | |
| 5 Year | 0,671 |
| Impact Factor | |
| Journal | 0,38 |
| Citation Indicator | |
| Rank by Journal | Immunology 146/174 (Q4) |
| Citation Indicator | Microbiology 120/142 (Q4) |
| Citable | 42 |
| Items | |
| Total | 40 |
| Articles | |
| Total | 2 |
| Reviews | |
| Scimago | 28 |
| H-index | |
| Scimago | 0,439 |
| Journal Rank | |
| Scimago | Immunology and Microbiology (miscellaneous) Q4 |
| Quartile Score | Medicine (miscellaneous) Q3 |
| Scopus | 438/167=2,6 |
| Scite Score | |
| Scopus | General Immunology and Microbiology 31/45 (Q3) |
| Scite Score Rank | |
| Scopus | 0,760 |
| SNIP | |
| Days from | 225 |
| submission | |
| to acceptance | |
| Days from | 118 |
| acceptance | |
| to publication | |
| Acceptance | 19% |
| Rate |
| 2019 | |
|---|---|
| Total Cites WoS |
485 |
| Impact Factor | 1,086 |
| Impact Factor without Journal Self Cites |
0,864 |
| 5 Year Impact Factor |
1,233 |
| Immediacy Index |
0,286 |
| Citable Items |
42 |
| Total Articles |
40 |
| Total Reviews |
2 |
| Cited Half-Life |
5,8 |
| Citing Half-Life |
7,7 |
| Eigenfactor Score |
0,00059 |
| Article Influence Score |
0,246 |
| % Articles in Citable Items |
95,24 |
| Normalized Eigenfactor |
0,07317 |
| Average IF Percentile |
7,690 |
| Scimago H-index |
27 |
| Scimago Journal Rank |
0,352 |
| Scopus Scite Score |
320/161=2 |
| Scopus Scite Score Rank |
General Immunology and Microbiology 35/45 (Q4) |
| Scopus SNIP |
0,492 |
| Acceptance Rate |
16% |
| Acta Microbiologica et Immunologica Hungarica | |
|---|---|
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| Acta Microbiologica et Immunologica Hungarica | |
|---|---|
| Language | English |
| Size | A4 |
| Year of Foundation |
1954 |
| Volumes per Year |
1 |
| Issues per Year |
4 |
| Founder | Magyar Tudományos Akadémia |
| Founder's Address |
H-1051 Budapest, Hungary, Széchenyi István tér 9. |
| Publisher | Akadémiai Kiadó |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 1217-8950 (Print) |
| ISSN | 1588-2640 (Online) |
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