View More View Less
  • 1 University of Pisa, Italy
Restricted access

Purchase article

USD  $25.00

1 year subscription (Individual Only)

USD  $784.00

Enterococci are opportunistic bacteria that cause severe infections in animals and humans, capable to acquire, express, and transfer antimicrobial resistance. Susceptibility to 21 antimicrobial agents was tested by the disk diffusion method in 222 Enterococcus spp. strains isolated from the fecal samples of 287 healthy domestic dogs. Vancomycin and ampicillin minimum inhibitory concentrations (MICs) and high-level aminoglycoside resistance (HLAR) tests were also performed. Isolates showed resistance mainly to streptomycin (88.7%), neomycin (80.6%), and tetracycline (69.4%). Forty-two (18.9%) isolates showed an HLAR to streptomycin and 15 (6.7%) to gentamicin. Vancomycin and ampicillin MIC values showed 1 and 18 resistant strains, respectively. One hundred and thirty-six (61.2%) strains were classified as multidrug resistant and six (2.7%) strains as possibly extensively drug-resistant bacteria. Enterococcus faecium and Enterococcus faecalis were the most prevalent antimicrobial resistant species. Companion animals, which often live in close contact with their owners and share the same environment, represent a serious source of enterococci resistant to several antibiotics; for this reason, they may be a hazard for public health by providing a conduit for the entrance of resistance genes into the community.

  • 1.

    Byappanahalli, M. N., Nevers, M. B., Korajkic, A., Staley, Z. R., Harwood, V. J.: Enterococci in the environment. Microbiol Mol Bio Rev 4, 685706 (2012).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 2.

    Franz, C. M., Huch, M., Abriouel, H., Holzapfel, W., Galvez, A.: Enterococci as probiotics and their implications in food safety. Int J Food Microbiol 151, 125140 (2011).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 3.

    Herczegh, A., Gyurkovics, M., Ghidan, A., Megyesi, M., Lohinai, Z.: Effect of dentin powder on the antimicrobial properties of hyperpure chlorine-dioxide and its comparison to conventional endodontic disinfecting agents. Acta Microbiol Immunol Hung 61, 209220 (2014).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 4.

    Robbins, K. M., Suyemoto, M. M., Lyman, R. L., Martin, M. P., Barnes, H. J., Borst, L. B.: An outbreak and source investigation of enterococcal spondylitis in broiler caused by Enterococcus cecorum. Avian Dis 56, 768773 (2012).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 5.

    Šeputienė, V., Bogdaitė, A., Ružauskas, M., Sužiedėlienė, E.: Antibiotic resistance genes and virulence factors in Enterococcus faecium and Enterococcus faecalis from diseased farm animals: Pigs, cattle and poultry. Pol J Vet Sci 3, 431438 (2012).

    • Search Google Scholar
    • Export Citation
  • 6.

    Abbot, Y., Kirby, B. M., Karczmarczk, M., Markey, B. K., Leonard, F. C., Fitzgerald, S.: High-level gentamicin-resistant and vancomycin-resistant Enterococcus faecium isolated from a wound in a dog. J Small Anim Pract 50, 194197 (2009).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 7.

    Semedo-Lemsaddek, T., Tavares, M., São Braz, B., Tavares, L., Oliveira, M.: Enterococcal infective endocarditis following periodontal disease in dogs. PLoS One 11, e0146860 (2016).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 8.

    Tendolkar, P. M., Baghdayan, A. S., Shankar, N.: Pathogenic enterococci: New developments in the 21st century. Cell Mol Life Sci 60, 26222636 (2003).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 9.

    Hegstad, K., Mikalsenm, T., Coque, T. M., Werner, G., Sundsfjord, A.: Mobile genetics elements and their contribution to the emergence of antimicrobial resistant Enterococcus faecalis and Enterococcus faecium. Clin Microbiol Infect 16, 541554 (2010).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 10.

    Bauer, A., Kirby, W. M. N., Sherris, J. C., Turk, M.: Antibiotic susceptibility testing by a standardized single disc method. Am J Pathol 45, 493496 (1966).

    • Search Google Scholar
    • Export Citation
  • 11.

    Clinical and Laboratory Standards Institute (CLSI): Performance standards for antimicrobial susceptibility testing, seventeenth informational supplement. Clinical and Laboratory Standards Institute document M100-S17, Clinical and Laboratory Standards Institute, Wayne, PA, USA, 2007.

    • Search Google Scholar
    • Export Citation
  • 12.

    The European Committee on Antimicrobial Susceptibility Testing (EUCAST). Breakpoint tables for interpretation of MICs and zone diameters. Version 3.1, 2013. Retrieved from http://www.eucast.org

    • Search Google Scholar
    • Export Citation
  • 13.

    Clinical and Laboratory Standards Institute (CLSI). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard, Seventh edition. Clinical and Laboratory Standards Institute document M7-A7. Clinical and Laboratory Standards Institute, Wayne, PA, USA, 2006.

    • Search Google Scholar
    • Export Citation
  • 14.

    Magiorakos, A. P., Srinivasan, A., Carey, R. B., Carmeli, Y., Falagas, M. E., Giske, C. G., Harbarth, S., Hindler, J. F., Kahlmeter, G., Olsson-Liljequist, B., Paterson, D. L., Rice, L. B., Stelling, J., Struelens, M. J., Vatopoulos, A., Weber, J. T., Monnet, D. L.: Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: An international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 18, 268281 (2012).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 15.

    Devriese, L. A., Cruz Colque, J. I., De Herdt, P., Haesebrouck, F.: Identification and composition of the tonsillar and anal enterococcal and streptococcal flora of dogs and cats. J Appl Bacteriol 73, 421425 (1992).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 16.

    Ossiprandi, M. C., Bottarelli, E., Cattabiani, F., Bianchi, E.: Susceptibility to vancomycin and other antibiotics of 165 Enterococcus strains isolated from dogs in Italy. Comp Immunol Microbiol Infect Dis 31, 19 (2008).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 17.

    Iseppi, R., Messi, P., Anacarso, I., Bondi, M., Sabia, C., Condò, C., de Niederhausern, S.: Antimicrobial resistance and virulence traits in Enterococcus strains isolated from dogs and cats. New Microbiol 38, 369378 (2015).

    • Search Google Scholar
    • Export Citation
  • 18.

    Hollenbeck, B. L., Rice, L. B.: Intrinsic and acquired resistance mechanisms in Enterococcus. Virulence 5, 421433 (2012).

  • 19.

    Guardabassi, L., Schwarz, S., Lloyd, D. H.: Pet animals as reservoirs of antimicrobial-resistant bacteria. J Antimicrob Chemother 54, 321332 (2004).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 20.

    Sun, Y., Cai, Y., Liu, X., Bai, N., Liang, B., Wang, R.: The emergence of clinical resistance to tigecycline. Int J Antimicrob Agents 41, 110116 (2013).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 21.

    Redgrave, L. S., Sutton, S. B., Webber, M. A., Piddock, L. J. V.: Fluoroquinolone resistance: Mechanism, impact on bacteria, and role in evolutionary success. Trends Microbiol 22, 438445 (2014).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 22.

    Jaglic, Z., Vlkova, H., Bardon, J., Michu, E., Cervinkova, D., Babak, V.: Distribution, characterization and genetic bases of erythromycin resistance in staphylococci and enterococci originating from livestock. Zoonoses Public Health 59, 202211 (2012).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 23.

    Adhikari, L.: High-level aminoglycoside resistance and reduced susceptibility to vancomycin in nosocomial enterococci. J Glob Infect Dis 2, 231235 (2010).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 24.

    Padmasini, E., Padmaraj, R., Srivani Ramesh, S.: High level aminoglycoside resistance and distribution of aminoglycoside resistant genes among clinical isolates of Enterococcus species in Chennai, India. Sci World J 2014, 329157 (2014).

    • Crossref
    • Search Google Scholar
    • Export Citation
  • 25.

    Jackson, C. R., Fedorka-Cray, P. J., Davis, J. A., Barrett, J. B., Brousse, J. H., Gustafson, J., Kucher, M.: Mechanisms of antimicrobial resistance and genetic relatedness among enterococci isolated from dogs and cats in the United States. J Appl Microbiol 108, 21712179 (2010).

    • Search Google Scholar
    • Export Citation
  • 26.

    Jovanović, M., Milošević, B., Tošić, T., Stevanović, G., Mioljević, V., Indić, N., Velebit, B., Zervos, M.: Molecular typing, pathogenicity factor genes and antimicrobial susceptibility of vancomycin resistant enterococci in Belgrade, Serbia. Acta Microbiol Immunol Hung 62, 147160 (2015).

    • Crossref
    • Search Google Scholar
    • Export Citation

 

The author instruction is available in PDF.
Please, download the file from HERE

Senior editors

Editor-in-Chief: Prof. Dóra Szabó (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Managing Editor: Dr. Béla Kocsis (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Co-editor: Dr. Andrea Horváth (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Editorial Board

  • Prof. Éva ÁDÁM (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Sebastian AMYES (Department of Medical Microbiology, University of Edinburgh, Edinburgh, UK.)
  • Dr. Katalin BURIÁN (Institute of Clinical Microbiology University of Szeged, Szeged, Hungary; Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary.)
  • Dr. Orsolya DOBAY (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Ildikó Rita DUNAY (Institute of Inflammation and Neurodegeneration, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany; Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany)
  • Prof. Levente EMŐDY(Department of Medical Microbiology and Immunology, University of Pécs, Pécs, Hungary.)
  • Prof. Anna ERDEI (Department of Immunology, Eötvös Loránd University, Budapest, Hungary, MTA-ELTE Immunology Research Group, Eötvös Loránd University, Budapest, Hungary.)
  • Prof. Éva Mária FENYŐ (Division of Medical Microbiology, University of Lund, Lund, Sweden)
  • Prof. László FODOR (Department of Microbiology and Infectious Diseases, University of Veterinary Medicine, Budapest, Hungary)
  • Prof. József KÓNYA (Department of Medical Microbiology, University of Debrecen, Debrecen, Hungary)
  • Prof. Yvette MÁNDI (Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary)
  • Prof. Károly MÁRIALIGETI (Department of Microbiology, Eötvös Loránd University, Budapest, Hungary)
  • Prof. János MINÁROVITS (Department of Oral Biology and Experimental Dental Research, University of Szeged, Szeged, Hungary)
  • Prof. Béla NAGY (Centre for Agricultural Research, Institute for Veterinary Medical Research, Budapest, Hungary.)
  • Prof. István NÁSZ (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Kristóf NÉKÁM (Hospital of the Hospitaller Brothers in Buda, Budapest, Hungary.)
  • Dr. Eszter OSTORHÁZI (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Rozália PUSZTAI (Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary)
  • Prof. Peter L. RÁDY (Department of Dermatology, University of Texas, Houston, Texas, USA)
  • Prof. Éva RAJNAVÖLGYI (Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary)
  • Prof. Ferenc ROZGONYI (Institute of Laboratory Medicine, Semmelweis University, Budapest, Hungary)
  • Prof. Zsuzsanna SCHAFF (2nd Department of Pathology, Semmelweis University, Budapest, Hungary)
  • Prof. Joseph G. SINKOVICS (The Cancer Institute, St. Joseph’s Hospital, Tampa, Florida, USA)
  • Prof. Júlia SZEKERES (Department of Medical Biology, University of Pécs, Pécs, Hungary.)
  • Prof. Mária TAKÁCS (National Reference Laboratory for Viral Zoonoses, National Public Health Center, Budapest, Hungary.)
  • Prof. Edit URBÁN (Department of Medical Microbiology and Immunology University of Pécs, Pécs, Hungary; Institute of Translational Medicine, University of Pécs, Pécs, Hungary.)

 

Editorial Office:
Akadémiai Kiadó Zrt.
Budafoki út 187-187, A/3, H-1117 Budapest, Hungary

Editorial Correspondence:
Acta Microbiologica et Immunologica Hungarica
Institute of Medical Microbiology
Semmelweis University
P.O. Box 370
H-1445 Budapest, Hungary
Phone: + 36 1 459 1500 ext. 56101
Fax: (36 1) 210 2959
E-mail: amih@med.semmelweis-univ.hu

 Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • Chemical Abstracts
  • Global Health
  • Index Medicus
  • Index Veterinarius
  • Medline
  • Referativnyi Zhurnal
  • SCOPUS
  • Science Citation Index Expanded
2020  
Total Cites 662
WoS
Journal
Impact Factor
2,048
Rank by Immunology 145/162(Q4)
Impact Factor Microbiology 118/137 (Q4)
Impact Factor 1,904
without
Journal Self Cites
5 Year 0,671
Impact Factor
Journal  0,38
Citation Indicator  
Rank by Journal  Immunology 146/174 (Q4)
Citation Indicator  Microbiology 120/142 (Q4)
Citable 42
Items
Total 40
Articles
Total 2
Reviews
Scimago 28
H-index
Scimago 0,439
Journal Rank
Scimago Immunology and Microbiology (miscellaneous) Q4
Quartile Score Medicine (miscellaneous) Q3
Scopus 438/167=2,6
Scite Score  
Scopus General Immunology and Microbiology 31/45 (Q3)
Scite Score Rank  
Scopus 0,760
SNIP
Days from  225
submission
to acceptance
Days from  118
acceptance
to publication
Acceptance 19%
Rate

2019  
Total Cites
WoS
485
Impact Factor 1,086
Impact Factor
without
Journal Self Cites
0,864
5 Year
Impact Factor
1,233
Immediacy
Index
0,286
Citable
Items
42
Total
Articles
40
Total
Reviews
2
Cited
Half-Life
5,8
Citing
Half-Life
7,7
Eigenfactor
Score
0,00059
Article Influence
Score
0,246
% Articles
in
Citable Items
95,24
Normalized
Eigenfactor
0,07317
Average
IF
Percentile
7,690
Scimago
H-index
27
Scimago
Journal Rank
0,352
Scopus
Scite Score
320/161=2
Scopus
Scite Score Rank
General Immunology and Microbiology 35/45 (Q4)
Scopus
SNIP
0,492
Acceptance
Rate
16%

 

Acta Microbiologica et Immunologica Hungarica
Publication Model Online only Hybrid
Submission Fee none
Article Processing Charge 1100 EUR/article
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription fee 2021 Online subsscription: 652 EUR / 812 USD
Subscription fee 2022 Online subsscription: 662 EUR / 832 USD
Print + online subscription: 740 EUR / 930 USD
Subscription Information Online subscribers are entitled access to all back issues published by Akadémiai Kiadó for each title for the duration of the subscription, as well as Online First content for the subscribed content.
Purchase per Title Individual articles are sold on the displayed price.

Acta Microbiologica et Immunologica Hungarica
Language English
Size A4
Year of
Foundation
1954
Publication
Programme
2021 Volume 68
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1217-8950 (Print)
ISSN 1588-2640 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Jun 2021 34 0 0
Jul 2021 2 0 0
Aug 2021 2 0 0
Sep 2021 5 2 3
Oct 2021 20 1 1
Nov 2021 11 0 0
Dec 2021 0 0 0