De Oliveira DMP, Forde BM, Kidd TJ, Harris PNA, Schembri MA, Beatson SA, et al. Antimicrobial resistance in ESKAPE pathogens. Clin Microbiol Rev 2020; 33(3): e00181–19. https://doi.org/10.1128/CMR.00181-19.

De Oliveira DMP, Forde BM, Kidd TJ, Harris PNA, Schembri MA, Beatson SA, et al. Antimicrobial resistance in ESKAPE pathogens. Clin Microbiol Rev 2020; 33(3): e00181–19. https://doi.org/10.1128/CMR.00181-19.)| false
• Search Google Scholar
• Export Citation

Reynolds D, Kollef M. The epidemiology and pathogenesis and treatment of Pseudomonas aeruginosa infections: an Update. Drugs 2021; 81(18): 2117–31. https://doi.org/10.1007/s40265-021-01635-6.

Reynolds D, Kollef M. The epidemiology and pathogenesis and treatment of Pseudomonas aeruginosa infections: an Update. Drugs 2021; 81(18): 2117–31. https://doi.org/10.1007/s40265-021-01635-6.)| false
• Search Google Scholar
• Export Citation

Behzadi P, Baráth Z, Gajdács M. It’s not easy being green: a narrative review on the microbiology, virulence and therapeutic prospects of multidrug-resistant Pseudomonas aeruginosa. Antibiotics 2021; 10(1): 42. https://doi.org/10.3390/antibiotics10010042.

Behzadi P, Baráth Z, Gajdács M. It’s not easy being green: a narrative review on the microbiology, virulence and therapeutic prospects of multidrug-resistant Pseudomonas aeruginosa. Antibiotics 2021; 10(1): 42. https://doi.org/10.3390/antibiotics10010042.)| false
• Search Google Scholar
• Export Citation

Migiyama Y, Sakata S, Iyama S, Tokunaga K, Saruwatari K, Tomita Y, et al. Airway Pseudomonas aeruginosa density in mechanically ventilated patients: clinical impact and relation to therapeutic efficacy of antibiotics. Crit Care 2021; 25(1): 59. https://doi.org/10.1186/s13054-021-03488-7.

Migiyama Y, Sakata S, Iyama S, Tokunaga K, Saruwatari K, Tomita Y, et al. Airway Pseudomonas aeruginosa density in mechanically ventilated patients: clinical impact and relation to therapeutic efficacy of antibiotics. Crit Care 2021; 25(1): 59. https://doi.org/10.1186/s13054-021-03488-7.)| false
• Search Google Scholar
• Export Citation

Mekonnen SA, El Husseini N, Turdiev A, Carter JA, Belew AT, El-Sayed NM, et al. Catheter-associated urinary tract infection by Pseudomonas aeruginosa progresses through acute and chronic phases of infection. Proc Natl Acad Sci USA 2022; 119(50): e2209383119. https://doi.org/10.1073/pnas.2209383119.

Mekonnen SA, El Husseini N, Turdiev A, Carter JA, Belew AT, El-Sayed NM, et al. Catheter-associated urinary tract infection by Pseudomonas aeruginosa progresses through acute and chronic phases of infection. Proc Natl Acad Sci USA 2022; 119(50): e2209383119. https://doi.org/10.1073/pnas.2209383119.)| false
• Search Google Scholar
• Export Citation

Gomersall J, Mortimer K, Hassan D, Whitehead KA, Slate AJ, Ryder SF, et al. Ten-year analysis of bacterial colonization and outcomes of major burn patients with a focus on Pseudomonas aeruginosa. Microorganisms 2023; 12(1): 42. https://doi.org/10.3390/microorganisms12010042.

Gomersall J, Mortimer K, Hassan D, Whitehead KA, Slate AJ, Ryder SF, et al. Ten-year analysis of bacterial colonization and outcomes of major burn patients with a focus on Pseudomonas aeruginosa. Microorganisms 2023; 12(1): 42. https://doi.org/10.3390/microorganisms12010042.)| false
• Search Google Scholar
• Export Citation

Paprocka P, Durnaś B, Mańkowska A, Król G, Wollny T, Bucki R. Pseudomonas aeruginosa infections in cancer patients. Pathogens 2022; 11(6): 679. https://doi.org/10.3390/pathogens11060679.

Paprocka P, Durnaś B, Mańkowska A, Król G, Wollny T, Bucki R. Pseudomonas aeruginosa infections in cancer patients. Pathogens 2022; 11(6): 679. https://doi.org/10.3390/pathogens11060679.)| false
• Search Google Scholar
• Export Citation

Yakout MA, Abdelwahab IA. Diabetic foot ulcer infections and Pseudomonas aeruginosa biofilm production during the COVID-19 pandemic. J Pure Appl Microbiol 2022; 16(1): 138–46. https://doi.org/10.22207/JPAM.16.1.02.

Yakout MA, Abdelwahab IA. Diabetic foot ulcer infections and Pseudomonas aeruginosa biofilm production during the COVID-19 pandemic. J Pure Appl Microbiol 2022; 16(1): 138–46. https://doi.org/10.22207/JPAM.16.1.02.)| false
• Search Google Scholar
• Export Citation

Rossi E, La Rosa R, Bartell JA, Marvig RL, Haagensen JAJ, Sommer LM, et al. Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis. Nat Rev Microbiol 2021; 19(5): 331–42. https://doi.org/10.1038/s41579-020-00477-5.

Rossi E, La Rosa R, Bartell JA, Marvig RL, Haagensen JAJ, Sommer LM, et al. Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis. Nat Rev Microbiol 2021; 19(5): 331–42. https://doi.org/10.1038/s41579-020-00477-5.)| false
• Search Google Scholar
• Export Citation

Murray CJL, Ikuta KS, Sharara F, Swetschinski L, Robles Aguilar G, Gray A, et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet 2022; 399(10325): 629–55. https://doi.org/10.1016/S0140-6736(21)02724-0.

Murray CJL, Ikuta KS, Sharara F, Swetschinski L, Robles Aguilar G, Gray A, et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. Lancet 2022; 399(10325): 629–55. https://doi.org/10.1016/S0140-6736(21)02724-0.)| false
• Search Google Scholar
• Export Citation

Jangra V, Sharma N, Chhillar AK. Therapeutic approaches for combating Pseudomonas aeruginosa infections. Microbes Infect 2022; 24(4): 104950. https://doi.org/10.1016/j.micinf.2022.104950.

Jangra V, Sharma N, Chhillar AK. Therapeutic approaches for combating Pseudomonas aeruginosa infections. Microbes Infect 2022; 24(4): 104950. https://doi.org/10.1016/j.micinf.2022.104950.)| false
• Search Google Scholar
• Export Citation

CDC. Antibiotic resistance threats in the United States, 2019. Atlanta, GA: U.S. Department of Health and Human Services, CDC; 2019. Available online: https://www.cdc.gov/drugresistance/biggest-threats.html [Accessed 4 May 2024].

CDC. Antibiotic resistance threats in the United States, 2019. Atlanta, GA: U.S. Department of Health and Human Services, CDC; 2019. Available online: https://www.cdc.gov/drugresistance/biggest-threats.html [Accessed 4 May 2024].)| false
• Search Google Scholar
• Export Citation

Tacconelli E, Carrara E, Savoldi A, Harbarth S, Mendelson M, Monnet DL, et al. Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis. Lancet Infect Dis 2018; 18(3): 318–27. https://doi.org/10.1016/S1473-3099(17)30753-3.

Tacconelli E, Carrara E, Savoldi A, Harbarth S, Mendelson M, Monnet DL, et al. Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis. Lancet Infect Dis 2018; 18(3): 318–27. https://doi.org/10.1016/S1473-3099(17)30753-3.)| false
• Search Google Scholar
• Export Citation

Peykov S, Strateva T. Whole-genome sequencing-based resistome analysis of nosocomial multidrug-resistant non-fermenting Gram-negative pathogens from the Balkans. Microorganisms 2023; 11(3): 651. https://doi.org/10.3390/microorganisms11030651.

Peykov S, Strateva T. Whole-genome sequencing-based resistome analysis of nosocomial multidrug-resistant non-fermenting Gram-negative pathogens from the Balkans. Microorganisms 2023; 11(3): 651. https://doi.org/10.3390/microorganisms11030651.)| false
• Search Google Scholar
• Export Citation

WHO Regional Office for Europe/European Centre for Disease Prevention and Control. Antimicrobial resistance surveillance in Europe 2022 – 2020 data. Copenhagen: WHO Regional Office for Europe; 2022. Available online: https://www.ecdc.europa.eu/en/publications-data/antimicrobial-resistance-surveillance-europe-2022-2020-data [Accessed 3 May 2024].

WHO Regional Office for Europe/European Centre for Disease Prevention and Control. Antimicrobial resistance surveillance in Europe 2022 – 2020 data. Copenhagen: WHO Regional Office for Europe; 2022. Available online: https://www.ecdc.europa.eu/en/publications-data/antimicrobial-resistance-surveillance-europe-2022-2020-data [Accessed 3 May 2024].)| false
• Search Google Scholar
• Export Citation

European Centre for Disease Prevention and Control. Antimicrobial resistance in the EU/EEA (EARS-Net) – annual epidemiological report 2022. Stockholm: ECDC; 2023. Available online: https://www.ecdc.europa.eu/en/publications-data/surveillance-antimicrobial-resistance-europe-2022[Accessed 3 May 2024].

European Centre for Disease Prevention and Control. Antimicrobial resistance in the EU/EEA (EARS-Net) – annual epidemiological report 2022. Stockholm: ECDC; 2023. Available online: https://www.ecdc.europa.eu/en/publications-data/surveillance-antimicrobial-resistance-europe-2022 [Accessed 3 May 2024].)| false
• Search Google Scholar
• Export Citation

Glen KA, Lamont IL. β-lactam resistance in Pseudomonas aeruginosa: current status, future prospects. Pathogens 2021; 10(12): 1638. https://doi.org/10.3390/pathogens10121638.

Glen KA, Lamont IL. β-lactam resistance in Pseudomonas aeruginosa: current status, future prospects. Pathogens 2021; 10(12): 1638. https://doi.org/10.3390/pathogens10121638.)| false
• Search Google Scholar
• Export Citation

Yong D, Toleman MA, Giske CG, Cho HS, Sundman K, Lee K, et al. Characterization of a new metallo-β-Lactamase Gene, blaNDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae Sequence Type 14 from India. Antimicrob Agents Chemother 2009; 53(12): 5046–54. https://doi.org/10.1128/AAC.00774-09.

Yong D, Toleman MA, Giske CG, Cho HS, Sundman K, Lee K, et al. Characterization of a new metallo-β-Lactamase Gene, bla_NDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae Sequence Type 14 from India. Antimicrob Agents Chemother 2009; 53(12): 5046–54. https://doi.org/10.1128/AAC.00774-09.)| false
• Search Google Scholar
• Export Citation

Struelens MJ, Monnet DL, Magiorakos AP, Santos O’Connor F, Giesecke J, the European NDM-1 Survey Participants. New Delhi metallo-beta-lactamase 1–producing Enterobacteriaceae: emergence and response in Europe. Euro Surveill 2010; 15(46): 19716. https://doi.org/10.2807/ese.15.46.19716-en.

Struelens MJ, Monnet DL, Magiorakos AP, Santos O’Connor F, Giesecke J, the European NDM-1 Survey Participants. New Delhi metallo-beta-lactamase 1–producing Enterobacteriaceae: emergence and response in Europe. Euro Surveill 2010; 15(46): 19716. https://doi.org/10.2807/ese.15.46.19716-en.)| false
• Search Google Scholar
• Export Citation

Jovcic B, Lepsanovic Z, Suljagic V, Rackov G, Begovic J, Topisirovic L, et al. Emergence of NDM-1 metallo-β-lactamase in Pseudomonas aeruginosa clinical isolates from Serbia. Antimicrob Agents Chemother 2011; 55(8): 3929–31. https://doi.org/10.1128/AAC.00226-11.

Jovcic B, Lepsanovic Z, Suljagic V, Rackov G, Begovic J, Topisirovic L, et al. Emergence of NDM-1 metallo-β-lactamase in Pseudomonas aeruginosa clinical isolates from Serbia. Antimicrob Agents Chemother 2011; 55(8): 3929–31. https://doi.org/10.1128/AAC.00226-11.)| false
• Search Google Scholar
• Export Citation

Tsilipounidaki K, Gkountinoudis CG, Florou Z, Fthenakis GC, Miriagou V, Petinaki E. First detection and molecular characterization of Pseudomonas aeruginosa blaNDM-1 ST308 in Greece. Microorganisms 2023; 11(9): 2159. https://doi.org/10.3390/microorganisms11092159.

Tsilipounidaki K, Gkountinoudis CG, Florou Z, Fthenakis GC, Miriagou V, Petinaki E. First detection and molecular characterization of Pseudomonas aeruginosa bla_NDM-1 ST308 in Greece. Microorganisms 2023; 11(9): 2159. https://doi.org/10.3390/microorganisms11092159.)| false
• Search Google Scholar
• Export Citation

Rodriguez-R LM, Gunturu S, Harvey WT, Rosselló-Mora R, Tiedje JM, Cole JR, et al. The Microbial Genomes Atlas (MiGA) webserver: taxonomic and gene diversity analysis of Archaea and Bacteria at the whole genome level. Nucleic Acids Res 2018; 46(W1): W282–8. https://doi.org/10.1093/nar/gky467.

Rodriguez-R LM, Gunturu S, Harvey WT, Rosselló-Mora R, Tiedje JM, Cole JR, et al. The Microbial Genomes Atlas (MiGA) webserver: taxonomic and gene diversity analysis of Archaea and Bacteria at the whole genome level. Nucleic Acids Res 2018; 46(W1): W282–8. https://doi.org/10.1093/nar/gky467.)| false
• Search Google Scholar
• Export Citation

The European Committee on Antimicrobial Susceptibility Testing (EUCAST). Breakpoint tables for interpretation of MICs and zone diameters, Version 14.0., 2024. Available online: https://eucast.org [Accessed 8 May 2024].

The European Committee on Antimicrobial Susceptibility Testing (EUCAST). Breakpoint tables for interpretation of MICs and zone diameters, Version 14.0., 2024. Available online: https://eucast.org [Accessed 8 May 2024].)| false
• Search Google Scholar
• Export Citation

Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 2012;18(3): 268–81. https://doi.org/10.1111/j.1469-0691.2011.03570.x.

Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 2012;18(3): 268–81. https://doi.org/10.1111/j.1469-0691.2011.03570.x.)| false
• Search Google Scholar
• Export Citation

Kadri SS, Adjemian J, Lai YL, Spaulding AB, Ricotta E, Prevots DR, et al. Difficult-to-treat resistance in Gram-negative bacteremia at 173 US hospitals: retrospective cohort analysis of prevalence, predictors, and outcome of resistance to all first-line agents. Clin Infect Dis 2018; 67(12): 1803–14. https://doi.org/10.1093/cid/ciy378.

Kadri SS, Adjemian J, Lai YL, Spaulding AB, Ricotta E, Prevots DR, et al. Difficult-to-treat resistance in Gram-negative bacteremia at 173 US hospitals: retrospective cohort analysis of prevalence, predictors, and outcome of resistance to all first-line agents. Clin Infect Dis 2018; 67(12): 1803–14. https://doi.org/10.1093/cid/ciy378.)| false
• Search Google Scholar
• Export Citation

Lixandru BE, Cotar AI, Straut M, Usein CR, Cristea D, Ciontea S, et al. Carbapenemase-producing Klebsiella pneumoniae in Romania: a six-month survey. PLoS ONE 2015; 10(11): e0143214. https://doi.org/10.1371/journal.pone.0143214.

Lixandru BE, Cotar AI, Straut M, Usein CR, Cristea D, Ciontea S, et al. Carbapenemase-producing Klebsiella pneumoniae in Romania: a six-month survey. PLoS ONE 2015; 10(11): e0143214. https://doi.org/10.1371/journal.pone.0143214.)| false
• Search Google Scholar
• Export Citation

Poirel L, Nordmann P. Acquired carbapenem-hydrolyzing beta-lactamases and their genetic support. Curr Pharm Biotechnol 2002; 3(2): 117–27. https://doi.org/10.2174/1389201023378427.

Poirel L, Nordmann P. Acquired carbapenem-hydrolyzing beta-lactamases and their genetic support. Curr Pharm Biotechnol 2002; 3(2): 117–27. https://doi.org/10.2174/1389201023378427.)| false
• Search Google Scholar
• Export Citation

Afgan E, Nekrutenko A, Grüning BA, Blankenberg D, Goecks J, Schatz MC, et al. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update. Nucleic Acids Res 2022; 50(W1): W345–51. https://doi.org/10.1093/nar/gkac247.

Afgan E, Nekrutenko A, Grüning BA, Blankenberg D, Goecks J, Schatz MC, et al. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update. Nucleic Acids Res 2022; 50(W1): W345–51. https://doi.org/10.1093/nar/gkac247.)| false
• Search Google Scholar
• Export Citation

Curran B, Jonas D, Grundmann H, Pitt T, Dowson CG. Development of a multilocus sequence typing scheme for the opportunistic pathogen Pseudomonas aeruginosa. J Clin Microbiol 2004; 42(12): 5644–9. https://doi.org/10.1128/JCM.42.12.5644-5649.2004.

Curran B, Jonas D, Grundmann H, Pitt T, Dowson CG. Development of a multilocus sequence typing scheme for the opportunistic pathogen Pseudomonas aeruginosa. J Clin Microbiol 2004; 42(12): 5644–9. https://doi.org/10.1128/JCM.42.12.5644-5649.2004.)| false
• Search Google Scholar
• Export Citation

Thrane SW, Taylor VL, Lund O, Lam JS, Jelsbak L. Application of whole-genome sequencing data for O-specific antigen analysis and in silico serotyping of Pseudomonas aeruginosa isolates. J Clin Microbiol 2016; 54(7): 1782–8. https://doi.org/10.1128/JCM.00349-16.

Thrane SW, Taylor VL, Lund O, Lam JS, Jelsbak L. Application of whole-genome sequencing data for O-specific antigen analysis and in silico serotyping of Pseudomonas aeruginosa isolates. J Clin Microbiol 2016; 54(7): 1782–8. https://doi.org/10.1128/JCM.00349-16.)| false
• Search Google Scholar
• Export Citation

Russel J, Pinilla-Redondo R, Mayo-Muñoz D, Shah SA, Sørensen SJ. CRISPRCasTyper: automated identification, annotation, and classification of CRISPR-Cas loci. CRISPR J 2020; 3(6): 462–9. https://doi.org/10.1089/crispr.2020.0059.

Russel J, Pinilla-Redondo R, Mayo-Muñoz D, Shah SA, Sørensen SJ. CRISPRCasTyper: automated identification, annotation, and classification of CRISPR-Cas loci. CRISPR J 2020; 3(6): 462–9. https://doi.org/10.1089/crispr.2020.0059.)| false
• Search Google Scholar
• Export Citation

Tafaj S, Gona F, Rodrigues CF, Kapisyzi P, Caushi F, Rossen JW, et al. Whole-genome sequences of two NDM-1-producing Pseudomonas aeruginosa strains isolated in a clinical setting in Albania in 2018. Microbiol Resour Announc 2020; 9(1): e01291–19. https://doi.org/10.1128/MRA.01291-19.

Tafaj S, Gona F, Rodrigues CF, Kapisyzi P, Caushi F, Rossen JW, et al. Whole-genome sequences of two NDM-1-producing Pseudomonas aeruginosa strains isolated in a clinical setting in Albania in 2018. Microbiol Resour Announc 2020; 9(1): e01291–19. https://doi.org/10.1128/MRA.01291-19.)| false
• Search Google Scholar
• Export Citation

Kostyanev T, Nguyen MN, Markovska R, Stankova P, Xavier BB, Lammens C, et al. Emergence of ST654 Pseudomonas aeruginosa co-harbouring blaNDM-1 and blaGES-5 in novel class I integron In1884 from Bulgaria. J Glob Antimicrob Resist 2020; 22: 672–3. https://doi.org/10.1016/j.jgar.2020.06.008.

Kostyanev T, Nguyen MN, Markovska R, Stankova P, Xavier BB, Lammens C, et al. Emergence of ST654 Pseudomonas aeruginosa co-harbouring bla_NDM-1 and bla_GES-5 in novel class I integron In1884 from Bulgaria. J Glob Antimicrob Resist 2020; 22: 672–3. https://doi.org/10.1016/j.jgar.2020.06.008.)| false
• Search Google Scholar
• Export Citation

Kabic J, Fortunato G, Vaz-Moreira I, Kekic D, Jovicevic M, Pesovic J, et al. Dissemination of metallo-β-lactamase-producing Pseudomonas aeruginosa in Serbian hospital settings: expansion of ST235 and ST654 clones. Int J Mol Sci 2023; 24(2): 1519. https://doi.org/10.3390/ijms24021519.

Kabic J, Fortunato G, Vaz-Moreira I, Kekic D, Jovicevic M, Pesovic J, et al. Dissemination of metallo-β-lactamase-producing Pseudomonas aeruginosa in Serbian hospital settings: expansion of ST235 and ST654 clones. Int J Mol Sci 2023; 24(2): 1519. https://doi.org/10.3390/ijms24021519.)| false
• Search Google Scholar
• Export Citation

Seemann T. Prokka: rapid prokaryotic genome annotation. Bioinformatics 2014; 30(14): 2068–9. https://doi.org/10.1093/bioinformatics/btu153.

Seemann T. Prokka: rapid prokaryotic genome annotation. Bioinformatics 2014; 30(14): 2068–9. https://doi.org/10.1093/bioinformatics/btu153.)| false
• Search Google Scholar
• Export Citation

Page AJ, Cummins CA, Hunt M, Wong VK, Reuter S, Holden MTG, et al. Roary: rapid large-scale prokaryote pan genome analysis. Bioinformatics 2015; 31(22): 3691–3. https://doi.org/10.1093/bioinformatics/btv421.

Page AJ, Cummins CA, Hunt M, Wong VK, Reuter S, Holden MTG, et al. Roary: rapid large-scale prokaryote pan genome analysis. Bioinformatics 2015; 31(22): 3691–3. https://doi.org/10.1093/bioinformatics/btv421.)| false
• Search Google Scholar
• Export Citation

Stamatakis A. RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. Bioinformatics 2014; 30(9): 1312–3. https://doi.org/10.1093/bioinformatics/btu033.

Stamatakis A. RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. Bioinformatics 2014; 30(9): 1312–3. https://doi.org/10.1093/bioinformatics/btu033.)| false
• Search Google Scholar
• Export Citation

Letunic I, Bork P. Interactive Tree of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation. Nucleic Acids Res 2021; 49(W1): W293–6. https://doi.org/10.1093/nar/gkab301.

Letunic I, Bork P. Interactive Tree of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation. Nucleic Acids Res 2021; 49(W1): W293–6. https://doi.org/10.1093/nar/gkab301.)| false
• Search Google Scholar
• Export Citation

European Centre for Disease Prevention and Control. Healthcare-associated infections acquired in intensive care units. In: ECDC. Annual epidemiological report for 2020. Stockholm: ECDC; 2024. Available online: https://www.ecdc.europa.eu/en/publications-data/healthcare-associated-infections-acquired-intensive-care-units-annual [Accessed 8 May 2024].

European Centre for Disease Prevention and Control. Healthcare-associated infections acquired in intensive care units. In: ECDC. Annual epidemiological report for 2020. Stockholm: ECDC; 2024. Available online: https://www.ecdc.europa.eu/en/publications-data/healthcare-associated-infections-acquired-intensive-care-units-annual [Accessed 8 May 2024].)| false
• Search Google Scholar
• Export Citation

Malisova L, Vrbova I, Pomorska K, Jakubu V, Zemlickova H. In vitro activity of cefiderocol against carbapenem-resistant Enterobacterales and Pseudomonas aeruginosa. Microb Drug Resist 2023; 29(10): 485–91. https://doi.org/10.1089/mdr.2023.0090.

Malisova L, Vrbova I, Pomorska K, Jakubu V, Zemlickova H. In vitro activity of cefiderocol against carbapenem-resistant Enterobacterales and Pseudomonas aeruginosa. Microb Drug Resist 2023; 29(10): 485–91. https://doi.org/10.1089/mdr.2023.0090.)| false
• Search Google Scholar
• Export Citation

Karakonstantis S, Rousaki M, Kritsotakis EI. Cefiderocol: systematic review of mechanisms of resistance, heteroresistance and in vivo emergence of resistance. Antibiotics 2022; 11(6): 723. https://doi.org/10.3390/antibiotics11060723.

Karakonstantis S, Rousaki M, Kritsotakis EI. Cefiderocol: systematic review of mechanisms of resistance, heteroresistance and in vivo emergence of resistance. Antibiotics 2022; 11(6): 723. https://doi.org/10.3390/antibiotics11060723.)| false
• Search Google Scholar
• Export Citation

Nurjadi D, Kocer K, Chanthalangsy Q, Klein S, Heeg K, Boutin S. New Delhi metallo-beta-lactamase facilitates the emergence of cefiderocol resistance in Enterobacter cloacae. Antimicrob Agents Chemother 2022; 66(2): e02011–21. https://doi.org/10.1128/AAC.02011-21.

Nurjadi D, Kocer K, Chanthalangsy Q, Klein S, Heeg K, Boutin S. New Delhi metallo-beta-lactamase facilitates the emergence of cefiderocol resistance in Enterobacter cloacae. Antimicrob Agents Chemother 2022; 66(2): e02011–21. https://doi.org/10.1128/AAC.02011-21.)| false
• Search Google Scholar
• Export Citation

Schneider I, Keuleyan E, Rasshofer R, Markovska R, Queenan AM, Bauernfeind A. VIM-15 and VIM-16, two new VIM-2-Like metallo-β-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. Antimicrob Agents Chemother 2008; 52(8): 2977–9. https://doi.org/10.1128/AAC.00175-08.

Schneider I, Keuleyan E, Rasshofer R, Markovska R, Queenan AM, Bauernfeind A. VIM-15 and VIM-16, two new VIM-2-Like metallo-β-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany. Antimicrob Agents Chemother 2008; 52(8): 2977–9. https://doi.org/10.1128/AAC.00175-08.)| false
• Search Google Scholar
• Export Citation

Strateva T, Setchanova L, Peykov S. Characterization of a Bulgarian VIM-2 metallo-β-lactamase-producing Pseudomonas aeruginosa clinical isolate belonging to the high-risk sequence type 111. Infect Dis (Lond) 2021; 53(11): 883–7. https://doi.org/10.1080/23744235.2021.1934531.

Strateva T, Setchanova L, Peykov S. Characterization of a Bulgarian VIM-2 metallo-β-lactamase-producing Pseudomonas aeruginosa clinical isolate belonging to the high-risk sequence type 111. Infect Dis (Lond) 2021; 53(11): 883–7. https://doi.org/10.1080/23744235.2021.1934531.)| false
• Search Google Scholar
• Export Citation

Stoikov I, Ivanov IN, Donchev D, Teneva D, Dobreva E, Hristova R, et al. Genomic characterization of IMP-producing Pseudomonas aeruginosa in Bulgaria reveals the emergence of IMP-100, a novel plasmid-mediated variant coexisting with a chromosomal VIM-4. Microorganisms 2023; 11(9): 2270. https://doi.org/10.3390/microorganisms11092270.

Stoikov I, Ivanov IN, Donchev D, Teneva D, Dobreva E, Hristova R, et al. Genomic characterization of IMP-producing Pseudomonas aeruginosa in Bulgaria reveals the emergence of IMP-100, a novel plasmid-mediated variant coexisting with a chromosomal VIM-4. Microorganisms 2023; 11(9): 2270. https://doi.org/10.3390/microorganisms11092270.)| false
• Search Google Scholar
• Export Citation

Oliver A, Rojo-Molinero E, Arca-Suarez J, Beşli Y, Bogaerts P, Cantón R, et al. Pseudomonas aeruginosa antimicrobial susceptibility profiles, resistance mechanisms and international clonal lineages: update from ESGARS-ESCMID/ISARPAE Group. Clin Microbiol Infect 2024; 30(4): 469–80. https://doi.org/10.1016/j.cmi.2023.12.026.

Oliver A, Rojo-Molinero E, Arca-Suarez J, Beşli Y, Bogaerts P, Cantón R, et al. Pseudomonas aeruginosa antimicrobial susceptibility profiles, resistance mechanisms and international clonal lineages: update from ESGARS-ESCMID/ISARPAE Group. Clin Microbiol Infect 2024; 30(4): 469–80. https://doi.org/10.1016/j.cmi.2023.12.026.)| false
• Search Google Scholar
• Export Citation

Opazo-Capurro A, Morales-León F, Jerez C, Olivares-Pacheco J, Alcalde-Rico M, González-Muñoz P, et al. Isolation of an extensively drug-resistant Pseudomonas aeruginosa exoS+/O4 strain belonging to the “high-risk” clone ST654 and coproducer of NDM-1 and the novel VIM-80. Microbiol Spectr 2022; 10(5): e01439–22. https://doi.org/10.1128/spectrum.01439-22.

Opazo-Capurro A, Morales-León F, Jerez C, Olivares-Pacheco J, Alcalde-Rico M, González-Muñoz P, et al. Isolation of an extensively drug-resistant Pseudomonas aeruginosa exoS⁺/O4 strain belonging to the “high-risk” clone ST654 and coproducer of NDM-1 and the novel VIM-80. Microbiol Spectr 2022; 10(5): e01439–22. https://doi.org/10.1128/spectrum.01439-22.)| false
• Search Google Scholar
• Export Citation

Bai Y, Gong Y e, Shen F, Li H, Cheng Y, Guo J, et al. Molecular epidemiological characteristics of carbapenem-resistant Pseudomonas aeruginosa clinical isolates in southeast Shanxi, China. J Glob Antimicrob Resist 2024; 36: 301–6. https://doi.org/10.1016/j.jgar.2023.12.029.

Bai Y, Gong Y e, Shen F, Li H, Cheng Y, Guo J, et al. Molecular epidemiological characteristics of carbapenem-resistant Pseudomonas aeruginosa clinical isolates in southeast Shanxi, China. J Glob Antimicrob Resist 2024; 36: 301–6. https://doi.org/10.1016/j.jgar.2023.12.029.)| false
• Search Google Scholar
• Export Citation

Zhao Y, Chen D, Ji B, Zhang X, Anbo M, Jelsbak L. Whole-genome sequencing reveals high-risk clones of Pseudomonas aeruginosa in Guangdong, China. Front Microbiol 2023; 14: 1117017. https://doi.org/10.3389/fmicb.2023.1117017.

Zhao Y, Chen D, Ji B, Zhang X, Anbo M, Jelsbak L. Whole-genome sequencing reveals high-risk clones of Pseudomonas aeruginosa in Guangdong, China. Front Microbiol 2023; 14: 1117017. https://doi.org/10.3389/fmicb.2023.1117017.)| false
• Search Google Scholar
• Export Citation

Botelho J, Tüffers L, Fuss J, Buchholz F, Utpatel C, Klockgether J, et al. Phylogroup-specific variation shapes the clustering of antimicrobial resistance genes and defence systems across regions of genome plasticity in Pseudomonas aeruginosa. EBioMedicine 2023; 90: 104532. https://doi.org/10.1016/j.ebiom.2023.104532.

Botelho J, Tüffers L, Fuss J, Buchholz F, Utpatel C, Klockgether J, et al. Phylogroup-specific variation shapes the clustering of antimicrobial resistance genes and defence systems across regions of genome plasticity in Pseudomonas aeruginosa. EBioMedicine 2023; 90: 104532. https://doi.org/10.1016/j.ebiom.2023.104532.)| false
• Search Google Scholar
• Export Citation

Wheatley RM, MacLean RC. CRISPR-Cas systems restrict horizontal gene transfer in Pseudomonas aeruginosa. ISME J 2021; 15(5): 1420–33. https://doi.org/10.1038/s41396-020-00860-3.

Wheatley RM, MacLean RC. CRISPR-Cas systems restrict horizontal gene transfer in Pseudomonas aeruginosa. ISME J 2021; 15(5): 1420–33. https://doi.org/10.1038/s41396-020-00860-3.)| false
• Search Google Scholar
• Export Citation

Fortunato G, Vaz-Moreira I, Gajic I, Manaia CM. Insight into phylogenomic bias of blaVIM-2 or blaNDM-1 dissemination amongst carbapenem-resistant Pseudomonas aeruginosa. Int J Antimicrob Agents 2023; 61(5): 106788. https://doi.org/10.1016/j.ijantimicag.2023.106788.

Fortunato G, Vaz-Moreira I, Gajic I, Manaia CM. Insight into phylogenomic bias of bla_VIM-2 or bla_NDM-1 dissemination amongst carbapenem-resistant Pseudomonas aeruginosa. Int J Antimicrob Agents 2023; 61(5): 106788. https://doi.org/10.1016/j.ijantimicag.2023.106788.)| false
• Search Google Scholar
• Export Citation