Authors:
Zouha Megdich Charles Nicolle Hospital, Laboratory of Microbiology, 1006, Tunis, Tunisia

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Asma Ferjani Charles Nicolle Hospital, Laboratory of Microbiology, 1006, Tunis, Tunisia
University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09, Research Laboratory «Antimicrobial Resistance», 1007, Tunis, Tunisia

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Sana Ferjani Charles Nicolle Hospital, Laboratory of Microbiology, 1006, Tunis, Tunisia
University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09, Research Laboratory «Antimicrobial Resistance», 1007, Tunis, Tunisia

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Lamia Kanzari Charles Nicolle Hospital, Laboratory of Microbiology, 1006, Tunis, Tunisia
University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09, Research Laboratory «Antimicrobial Resistance», 1007, Tunis, Tunisia

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Ahmed Fakhfakh Charles Nicolle Hospital, Laboratory of Microbiology, 1006, Tunis, Tunisia
University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09, Research Laboratory «Antimicrobial Resistance», 1007, Tunis, Tunisia

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Amel Rehaiem Charles Nicolle Hospital, Laboratory of Microbiology, 1006, Tunis, Tunisia
University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09, Research Laboratory «Antimicrobial Resistance», 1007, Tunis, Tunisia

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https://orcid.org/0000-0001-7245-1976
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I. Boutiba-Ben Boubaker Charles Nicolle Hospital, Laboratory of Microbiology, 1006, Tunis, Tunisia
University of Tunis El Manar, Faculty of Medicine of Tunis, LR99ES09, Research Laboratory «Antimicrobial Resistance», 1007, Tunis, Tunisia

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Abstract

Often dismissed as contaminants in blood cultures, Corynebacterium species can also cause infective endocarditis, a severe condition. We report an unusual case of Corynebacterium propinquum endocarditis in a non-immunocompromised individual on a native valve. Conflicting clinical and microbiological data led to 16S ribosomal sequencing to confirm the causative agent. Our case illustrates C. propinquum as a cause of infective endocarditis, and it demonstrates the utility of ancillary molecular diagnostic techniques to identify etiologic agents in difficult cases of infective endocarditis. C. propinquum should be recognized as a potential cause of infective endocarditis even on a native valve.

  • 1.

    Mylonakis E, Calderwood SB. Infective endocarditis in adults. N Engl J Med 2001; 345(18): 131830.

  • 2.

    Baddour LM, Wilson WR, Bayer AS, Fowler VG, Tleyjeh IM, Rybak MJ, et al. Infective endocarditis in adults: diagnosis, antimicrobial therapy,and management of complications: a scientific statement for healthcare professionals from the American Heart Association. Circulation 2015; 132: 143586.

    • Search Google Scholar
    • Export Citation
  • 3.

    Belmares J, Detterline S, Pak JB, Parada JP. Corynebacterium endocarditis species specific risk factors and outcomes. BMC Infect Dis 2007; 7: 4.

    • Search Google Scholar
    • Export Citation
  • 4.

    Funke G, von Graevenitz A, Clarridge JE, Bernard KA. Clinical microbiology of coryneform bacteria. Clin Microbiol Rev 1997; 10(1): 12559.

    • Search Google Scholar
    • Export Citation
  • 5.

    Bernard K.. The genus Corynebacterium and other medically relevant coryneform-like bacteria. J Clin Microbiol 2012; 50(10): 31528.

  • 6.

    Díez-Aguilar M, Ruiz-Garbajosa P, Fernández-Olmos A, Guisado P, Del Campo R, Quereda C, et al. Non-diphtheriae Corynebacterium species: an emerging respiratory pathogen. Eur J Clin Microbiol Infect Dis 2013; 32(6): 76972.

    • Search Google Scholar
    • Export Citation
  • 7.

    Otsuka Y, Ohkusu K, Kawamura Y, Baba S, Ezaki T, Kimura S. Emergence of multidrug-resistant Corynebacterium striatum as a nosocomial pathogen in longterm hospitalized patients with underlying diseases. Diagn Microbiol Infect Dis 2006; 54(2): 10914.

    • Search Google Scholar
    • Export Citation
  • 8.

    Todokoro D, Eguchi H, Yamada N, Sodeyama H, Hosoya R, Kishi S. Contact lensrelated infectious keratitis with white plaque formation caused by Corynebacteriumpropinquum. J Clin Microbiol 2015; 53(9): 30925.

    • Search Google Scholar
    • Export Citation
  • 9.

    Petit PL, Bok JW, Thompson J, Buiting AG, Coyle MB. Native-valve endocarditis due to CDC coryneform group ANF-3: report of a case and review of corynebacterial endocarditis. Clin Infect Dis 1994; 19(5): 897901.

    • Search Google Scholar
    • Export Citation
  • 10.

    Kawasaki Y, Matsubara K, Ishihara H, Nigami H, Iwata A, Kawaguchi K, et al. Corynebacterium propinquum as the first cause of infective endocarditis in childhood. J Infect Chemother 2014; 20(5): 3179.

    • Search Google Scholar
    • Export Citation
  • 11.

    Jangda U, Upadhyay A, Bagheri F, Patel NR, Mendelson RI. Corynebacterium propinquum: a rare cause of prosthetic valve endocarditis. Case Rep Med 2016; 2016: 1391789.

    • Search Google Scholar
    • Export Citation
  • 12.

    Rea B, Hawkins J, Min H, Maniglia R, Talati N. Laurel Glaser Corynebacterium propinquum endocarditis: a confounding presentation of a rare entity. https://doi.org/10.1016/j.carpath.2017.03.006.

    • Search Google Scholar
    • Export Citation
  • 13.

    Abdolrasouli A, Roushan A. Corynebacterium propinquum associated with acute, Nongonococcal urethritis. Sex Transm Dis 2013; 40(10): 829831.

    • Search Google Scholar
    • Export Citation
  • 14.

    Bernard K, Pacheco AL, Cunningham I, Gill N, Burdz T, Wiebe D. Emendation of the description of the species Corynebacterium propinquum to include strains which produce urease. Int J Syst Evol Microbiol 2013; 63(Pt 6): 214654.

    • Search Google Scholar
    • Export Citation
  • 15.

    Janda JM, Abbott SL. 16S rRNA gene sequencing for bacterial identification in the diagnostic laboratory: pluses, perils, and pitfalls. J Clin Microbiol Sept. 2007; 45(9): 27612764. https://doi.org/10.1128/JCM.01228-07.

    • Search Google Scholar
    • Export Citation
  • 16.

    Rovery C, Greub G, Lepidi H, Casalta JP, Habib G, Collart F, et al. PCR detection of bacteria on cardiac valves of patients with treated bacterial endocarditis. J Clin Microbiol 2005; 43(1): 1637.

    • Search Google Scholar
    • Export Citation
  • 17.

    Miller RJ, Chow B, Pillai D, Church D. Development and evaluation of a novel fast broad-range 16S ribosomal DNA PCR and sequencing assay for diagnosis of bacterial infective endocarditis: multi-year experience in a large Canadian healthcare zone and a literature review. BMC Infect Dis 2016; 16: 146.

    • Search Google Scholar
    • Export Citation
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Senior editors

Editor-in-Chief: Prof. Dóra Szabó (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Managing Editor: Dr. Béla Kocsis (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Co-editor: Dr. Andrea Horváth (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)

Editorial Board

  • Prof. Éva ÁDÁM (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Sebastian AMYES (Department of Medical Microbiology, University of Edinburgh, Edinburgh, UK.)
  • Dr. Katalin BURIÁN (Institute of Clinical Microbiology University of Szeged, Szeged, Hungary; Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary.)
  • Dr. Orsolya DOBAY (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Ildikó Rita DUNAY (Institute of Inflammation and Neurodegeneration, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany; Center for Behavioral Brain Sciences (CBBS), Magdeburg, Germany)
  • Prof. Levente EMŐDY(Department of Medical Microbiology and Immunology, University of Pécs, Pécs, Hungary.)
  • Prof. Anna ERDEI (Department of Immunology, Eötvös Loránd University, Budapest, Hungary, MTA-ELTE Immunology Research Group, Eötvös Loránd University, Budapest, Hungary.)
  • Prof. Éva Mária FENYŐ (Division of Medical Microbiology, University of Lund, Lund, Sweden)
  • Prof. László FODOR (Department of Microbiology and Infectious Diseases, University of Veterinary Medicine, Budapest, Hungary)
  • Prof. József KÓNYA (Department of Medical Microbiology, University of Debrecen, Debrecen, Hungary)
  • Prof. Yvette MÁNDI (Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary)
  • Prof. Károly MÁRIALIGETI (Department of Microbiology, Eötvös Loránd University, Budapest, Hungary)
  • Prof. János MINÁROVITS (Department of Oral Biology and Experimental Dental Research, University of Szeged, Szeged, Hungary)
  • Prof. Béla NAGY (Centre for Agricultural Research, Institute for Veterinary Medical Research, Budapest, Hungary.)
  • Prof. István NÁSZ (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Kristóf NÉKÁM (Hospital of the Hospitaller Brothers in Buda, Budapest, Hungary.)
  • Dr. Eszter OSTORHÁZI (Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary)
  • Prof. Rozália PUSZTAI (Department of Medical Microbiology and Immunobiology, University of Szeged, Szeged, Hungary)
  • Prof. Peter L. RÁDY (Department of Dermatology, University of Texas, Houston, Texas, USA)
  • Prof. Éva RAJNAVÖLGYI (Department of Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary)
  • Prof. Ferenc ROZGONYI (Institute of Laboratory Medicine, Semmelweis University, Budapest, Hungary)
  • Prof. Joseph G. SINKOVICS (The Cancer Institute, St. Joseph’s Hospital, Tampa, Florida, USA)
  • Prof. Júlia SZEKERES (Department of Medical Biology, University of Pécs, Pécs, Hungary.)
  • Prof. Mária TAKÁCS (National Reference Laboratory for Viral Zoonoses, National Public Health Center, Budapest, Hungary.)
  • Prof. Edit URBÁN (Department of Medical Microbiology and Immunology University of Pécs, Pécs, Hungary; Institute of Translational Medicine, University of Pécs, Pécs, Hungary.)

 

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Acta Microbiologica et Immunologica Hungarica
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Semmelweis University
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E-mail: amih@med.semmelweis-univ.hu

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Acta Microbiologica et Immunologica Hungarica
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Acta Microbiologica et Immunologica Hungarica
Language English
Size A4
Year of
Foundation
1954
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 1217-8950 (Print)
ISSN 1588-2640 (Online)

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