Abstract
Poliomyelitis was a disease feared worldwide, striking suddenly and paralysing mainly children for life. Monitoring of suspected cases of poliomyelitis is carried out with Acute Flaccid Paralysis (AFP) surveillance in Turkey. This study examines national data of AFP surveillance and the epidemiology of enteroviruses (EV) in Turkey from 2000 to 2019 and gives an overview of the detected serotypes of EVs. A total of 13,640 samples collected from patients with 5216 AFP pre-diagnosed cases (2 samples from each patient) and 3,208 contacts, during a 20-year period (2000–2019) were investigated. All isolated polioviruses were tested for their wild or vaccine origin according to the WHO recommended protocol by PCR and sequencing analysis were performed. Enterovirus positivity was detected in a total of 915 cases, which were identified as 204 Sabin-like polio virus (SLPV) and 711 non-polio enterovirus (NPEV). Of the 204 SLPV, 141 (69.1%) AFP were detected in patients and 63 (30.9%) were detected in samples taken from their contacts. Of the 711 NPEVs, 516 (72.5%) were from AFP cases and 195 (27.5%) were detected in samples taken from their contacts. It is concluded that the reason for the higher detection rate of NPEV in samples from AFP pre-diagnosed cases is attributed to the polio vaccination rates reaching 97% between 2008 and 2019 in Turkey. The most frequently detected NPEV serotypes were Coxackie A24, B3, and Echo 30. This retrospective study is the first comprehensive study in Turkey to evaluate the results of the AFP surveillance in the last 20 years.
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-
1.
https://talk.ictvonline.org/ictv-reports/ictv_online_report/positive-sense-rna-viruses/picornavirales/w/picornaviridae/681/genus-enterovirus at available: 13.01.2021.
-
2.
Pallansch MA, Oberste MS. Coxsackievirus, echovirus, and other enteroviruses. In: Gorbach SL, Bartlett JG, Blacklow NR, editors. Infectious diseases. Philadelphia, PA: Lippincott Williams & Wilkins; 2004. pp. 2047–53.
-
3.
Sawyer MH. Enterovirus infections: diagnosis and treatment. Semin Ped Infect Dis. 2002; 13: 40–7.
-
4.
Rotbart HA. Meningitis and encephalitis. In: Rotbart NR editor. Human enterovirus infections. Washington, DC: American Society for Microbiology; 1995. pp. 271–89.
-
5.
Jorba J, Diop OM, Iber J, . Update on vaccine-derived polioviruses — worldwide, January 2016–June 2017. Weekly/November 3 2017; 66: 1185–91.
-
6.
Enterovirus surveillance guidelines. Guidelines for enterovirus surveillance in support of the Polio Eradication Initiative; 2015. ISBN 978 92 890 5081 4. http://www.euro.who.int/__data/assets/pdf_file/0020/272810/EnterovirusSurveillanceGuidelines.pdf?ua=1.
-
7.
Taniuchi M, Begum S, Uddin MJ, . Kinetics of poliovirus shedding following oral vaccination as measured by quantitative reverse transcription-PCR versus culture. Loeffelholz MJ, ed. J Clin Microbiol 2015; 53: 206–11.
-
8.
Türkiye Cumhuriyeti, Sağlık Bakanlığı, Temel Sağlık Hizmetleri Genel Müdürlüğü, Genişletilmiş Bağışıklama Programı Genelgesi (2009). (Republic of Turkey, Ministry of Health, Ministry of Health, General Directorate of Primary Health Care Services, Circular on Extended Immunization Program). 2009/17. Ankara 2009.
-
9.
Nayir T, Nazlıcan E, Şahin M, Kara F, Alp Meşe E. Effects of immunization program on morbidity and mortality rates ofvaccine-preventable diseases in Turkey. Turk J Med Sci 2020; 50(8): 1909–15.
-
10.
WHO/IVB/04.10. Polio Manual; 2004, pp. 82–5.
-
11.
Poliovirus rRT-PCR ITD Kit, Programme on Immunisation, CDC. http://www.wpro.who.int/immunization/meetings/2012/polio_rtpcr_training_2012_meeting_report_annex6_7.pdf.
-
12.
Leading causes of mortality on the United States – Mexico border. Epidemiological Bull/PAHO 1999; 20(2).
-
13.
http://polioeradication.org/polio-today/polio-now/surveillance-indicators/.
-
14.
Soji OB, Olayinka OA, Tekena HO, Baba MM, Bukbuk DN, Olayinka OO. Non-polio enteroviruses implicated in acute flaccid paralysis in northern Nigeria. Res J Med Sci 2007; 2: 25–8.
-
15.
Shahmahmoodi S, Parvaneh N, Burns C, . Isolation of a type 3 vaccine-derived poliovirus (VDPV) from an Iranian child with X-linked agammaglobulinemia. Virus Res 2008; 137: 168–72.
-
16.
Chaves SS, Lobo S, Kennett M, . Coxsackie virus A24 infection presenting as acute flaccid paralysis. Lancet 2001; 357: 605.
-
17.
Antona D, Lévêque N, Chomel JJ, Dubrou S, Lévy-Bruhl D, Lina B. Surveillance of enteroviruses in France, 2000–2004. Eur J Clin Microbiol Infect Dis 2007; 26: 403–12.
-
18.
Bahri O, Rezig D, Nejma-Oueslati BB, . Enteroviruses in Tunisia: virological surveillance over 12 years (1992–2003). J Med Microbiol 2005; 54: 63–9.
-
19.
Mehrabi Z, Shahmahmoodi S, Eshraghian MR, . Molecular detection of different types of non-polio enteroviruses in acute flaccid paralysis cases and healthy children, a pilot study. J Clin Virol 2011; 50: 181–2.
-
20.
Ma JT, Chen H, Yuan F, Ma XM, Guan, GY, Zhan J. Typing and identification of non-polio enterovirus from acute flaccid paralysis cases in Ningxia, 1997–2011. Zhonghua Liu Xing Bing Xue Za Zhi 2012; 33: 1163–6.
-
21.
Bendig JW, Franklin OM, Hebden AK, . Coxsackievirus B3 sequences in the blood of a neonate with congenital myocarditis, plus serological evidence of maternal infection. J Med Virol 2003; 70: 606–9.
-
22.
Spanakis N, Manolis EN, Tsakris A, . Coxsackievirus B3 sequences in the myocardium of fatal cases in a cluster of acute myocarditis in Greece. J Clin Pathol 2005; 58: 357–60.
-
23.
Mistchenko AS, Viegas M, Latta MP, Barrero PR. Barrero PR. Molecular and epidemiologic analysis of enterovirus B neurological infection in Argentine children. J Clin Virol 2006; 37: 293–9.
-
24.
Roberts JA, Hobday LK, Ibrahim A, Aitken T, Thorley BR. Australian national enterovirus reference laboratory annual report, 2015. Commun Dis Intell (2018)2020 Apr 15; 44.
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