The principal component analysis is a practical method for multivariate statistical analyses. It can eliminate the correlation between sample indexes, and on the premise of keeping the main information of samples, extract a few representative principal components. This article adopts the input—output method and principal component analysis. It carries on the transverse comparison research on the effective utilization situation of human resources in China in 2008 and reveals the actual situation of efficient use of human resources in the provinces in China. The degree of effective use of human resources in Beijing is the highest, while in Ningxia is the lowest. It is closely related to the economic development. Finally, it puts forward the thoughts and suggestions of improving the effective use of human resources in China.