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  • 1 Department of Botany, Faculty of Sciences, Central Laboratory, Shahrekord University, Shahrekord, Iran
  • | 2 Medical Plants Research Center, Basic Health Sciences Institute Shahrekord University of Medical Sciences, Shahrekord, Iran
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Belonging to Lamiaceae family, the genus Teucrium L. is a rich source of secondary metabolites used in pharmacology and industrial medicine. This study aimed to investigate the flavonoid contents of methanol extract and the chemical markers of Teucrium at specific and infraspecific levels and identify the chemotypes of its accessions. Nineteen accessions, eight species, and five subspecies were collected from three sections (Teucris, Polium, and Scordium) belonging to the natural habitats in the west, southwest, centre, and south of Iran. Total flavonoid extraction was attained by the air-dried leaf of Teucrium species and 90% methanol. HPLC coupled with triple quadrupole mass analyser was applied to screen and identify the chemical constituents. Multivariate analyses were implemented by cluster and principal component analysis. Chemical investigation specified 148 chemical compounds, of which 135 flavonoids were tentatively identified. The most abundant derivatives belonged to flavones (41 derivatives), flavonols (37 derivatives), and isoflavonoids (22 derivatives). Based on the cluster analysis, 13 groups of chemical markers were formed in sections Teucris and Scordium and five groups in section Polium as chemotaxonomic indicators. The specified chemotypes were represented by ten in the sections Teucris and Scordium and by six in the section Polium. A relationship was suggested between type and flavonoid quantity (number), altitude, and geographical location. The present study provided valuable information for pharmacological research, bioactivity assessment, and chemotaxonomic purposes. This is the first report on the presence of chemotypes, chemical markers, and quality assessments for the genus Teucrium.

  • Ahmed, R. F., Elkhrisy, E. A., El-Kashak, W. A., El Raey, M. A., Nassar, M. I. and Aboutab, E. A. (2019): Structural characterization of polyphenolics in Livistona chinensis using HPLC-PDA-MS. –J. Adv. Pharm. Res. 3: 2329.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Alwahsh, M. A. A., Melati, Kh. and Wong, K. Ch. (2015): Chemical constituents and anti-oxidant activity of Teucrium barbeyanum Aschers. –Rec. Nat. Prod. 9: 159163.

    • Search Google Scholar
    • Export Citation
  • Antunes, T., Sevinate-Pinto, I., Barroso, J. G., Cavaleiro, C. and Salgueiro, L. R. (2004): Micromorphology of trichomes and composition of essential oil of Teucrium capitatum. –Flavour Fragr.J. 19: 336340.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Atay, I., Kirmizibekmez, H., Kaiser, M., Akaydin, G., Yesilada, E. and Tasdemir, D. (2016): Evaluation of in vitro antiprotozoal activity of Ajuga laxmannii and its secondary metabolites. –Pharm. Biol. 54: 18081814.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Bagheri Moghadam, H. and Kharazian, N. (2020): Morphologic and chemotaxonomic studies of some Teucrium L. (Lamiaceae) in Zagros region, Iran.–Iran J. Sci. Technol. Trans. Sci. 44: 933953.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Bezerra, A. G., Negri, G., Duarte-Almeida, J. M., Smaili, S. S. and Carlini, E. A. (2016): Phytochemical analysis of hydroethanolic extract of Turnera diffusa Willd. and evaluation of its effects on astrocyte cell death. –Einstein 14: 5663.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Boumerfeg, S., Baghiani, A., Djarmouni, M., Ameni, D., Adjadj, M., Belkhiri, F., Charef, N., Khennouf, S. and Arrar, L. (2012): Inhibitory activity on xanthine oxidase and antioxidant properties of Teucrium polium L. extracts.–Chinese Med. 3: 3041.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Bukhari, N. A., Al-Otaibi, R. A. and Ibhrahim, M. M. (2015): Biodiversity characteristics of Teucrium polium species in Saudi Arabia. –Saudi J.Biol. Sci. 22: 181185.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Calderon-Montano, J. M., Burgos-Moron, E., Perez-Guerrero, C. and Lopez-Lazaro, M. (2011): A review on the dietary flavonoid kaempferol.–Mini-Rev. Med. Chem. 11: 298344.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Dar, B. A., Lone, S. H., Shah, W. A. and Bhat, K. A. (2016): LC–MS guided isolation of bioactive principles from Iris hookeriana and bio evaluation of isolates for antimicrobial and antioxidant activities.–Drug Res. 66: 427431.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Delazar, A., Delnavazi, M. R., Yassa, N., Parkhideh, Sh., Delazar, N., Nahar, L. and Sarker, S. D. (2012): Essential oil composition and isolation of free radical-scavenging phenolic glycosides from the aerial parts of Ajuga chamaepitys growing in Iran. –Rev. Bras. Farmacogn. Braz. J. Pharm. 22: 299305.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Deng, Y., Li, C., Li, H. and Lu, Sh. (2018): Identification and characterization of flavonoid biosynthetic enzyme genes in Salvia miltiorrhiza (Lamiaceae). –Molecules 23: 14671487.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Dixit, A. K., Vaidya, S. and Devaliya, R. (2012): Agrobacterium rhizogenes MTCC 532 induced hairy root development in Tephrosia purpurea (L) and its effect on production of tephrosin. –J. Sci. Res. 4: 741748.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Elmasri, W. A., Yang, T., Tran, Ph., Hegazy, M. E. F., Hamood, A. N., Mechref, Y. and Pare, P. W. (2015): Teucrium polium phenylethanol and iridoid glycoside characterization and flavonoid inhibition of biofilm-forming Staphylococcus aureus. –J. Nat. Prod. 78: 29.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • El Sayed, M. A., Al-Gendy, A. A., Hamdan, D. I. and El-Shazly, A. M. (2017): Phytoconstituents, LC-ESI-MS profile, antioxidant and antimicrobial activities of Citrus x limon L. Burm. f. cultivar variegated pink Lemon.–J. Pharm. Sci. Res. 9: 375391.

    • Search Google Scholar
    • Export Citation
  • El Sayed, A. I., El-hamahmy, M. A. M., Rafudeen, M. S., Mohamed, A. H. and Oma, A. A. (2019): The impact of drought stress on antioxidant responses and accumulation of flavonolignans in milk thistle (Silybum marianum (L.) Gaertn.). –Plants 8: 118.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Ghazouani, N., Abderrabba, M. and Bouajila, J. (2016): Teucrium ramosissimum (Lamiaceae): volatile composition, seasonal variation, and pharmaceutical activity. –Anal. Lett. 49: 12581271.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Gonzales, G. B., Raes, K., Vanhoutte, H., Coelus, S., Smagghe, G. and Van Camp, J. (2015): Liquid chromatography-mass spectrometry coupled with multivariate analysis for the characterization and discrimination of extractable and non-extractable polyphenols and glucosinolates from red cabbage and Brussels sprout waste streams. –J. Chromatogr. A. 1402: 6070.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Grignon-Dubois, M. and Rezzonico, B. (2012): First phytochemical evidence of chemotypes for the seagrass Zostera noltii.–Plants 1(1): 2738

  • Grubešić, R. J., Kremer, D., Vladimir-Knežević, S. and Rodríguez, J. V. (2012): Analysis of polyphenols, phytosterols, and bitter principles in Teucrium L. species. –Cent. Eur. J. Biol. 7: 542550.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Hammer, O., Harper, D. A. T. and Ryan, P. D. (2001): PAST: paleontological statistics software package for education and data analysis. –Palaeontol. Electron. 4: 9.

    • Search Google Scholar
    • Export Citation
  • Hawas, U. W., Sharaf, M. and El-Ansari, M. A. (2008): Phytochemical studies and biological activity of Teucrium pilosum. –Curr. Chem. Biol. 2: 174177.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Hellal, Kh., Maulidiani, M., Ismail, I. S., Tan, Ch. P. and Abas, F. (2020): Antioxidant, α-glucosidase, and nitric oxide inhibitory activities of six Algerian traditional medicinal plant extracts and 1H-NMR-based metabolomics study of the active extract. –Molecules 25: 12471265.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Iwashina, T. (2015): Contribution to flower colors of flavonoids including anthocyanins: A review. –Nat. Prod. Comm. 10: 529544.

  • Jafari Dehkordi, F., Kharazian, N. and Lorigooini, Z. (2020): Characterization of flavonoid components in Scutellaria L. species (Lamiaceae) using fingerprinting analysis. –Acta Biol.Carcov. Bot. 62: 7996.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Jamzad, Z. (2012): Lamiaceae. – In: Asadi, M., Masoumi, A. A., Mozafarian, V. (eds): Flora Iran. Vol. 76. Research Institute of Forest and Rangelands, Tehran, pp. 4385.

    • Search Google Scholar
    • Export Citation
  • Jang, G. H., Kim, H. W., Lee, M. K., Jeong, S. Y., Bak, A. R., Lee, D. J. and Kim, J. B. (2018): Characterization and quantification of flavonoid glycosides in the Prunus genus by UPLC-DADQTOF/MS. –Saudi J.Biol. Sci. 25: 16221631.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Kontogiorgis, Ch., Ntella, M., Mpompou, L., Karallaki, F., Athanasios, P., Hadjipavlou-Litina, D. and Lazari, D. (2016): Study of the antioxidant activity of Thymus sibthorpii Bentham (Lamiaceae). –J. Enzyme Inhib. Med. Chem. 31(suppl. 4): 154159.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Kotta, S., Ansari, Sh. H. and Ali, J. (2013): Exploring scientifically proven herbal aphrodisiacs. –Pharmacogn. Rev. 7: 110.

  • Krauze-Baranowska, M., Głód, D., Kula, M., Majdan, M., Hałasa, R., Matkowski, A., Kozlowska, W. and Kawiak, A. (2014): Chemical composition and biological activity of Rubus idaeus shoots, a traditional herbal remedy of Eastern Europe. –BMC. Complement. Altern. Med. 14: 112.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Kumar, V., Sood, H. and Chauhan, R. S. (2016): Optimization of a preparative RP-HPLC method for isolation and purification of picrosides in Picrorhiza kurroa. –J. Plant Biochem. Biotech. 25: 208214.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Lee, J. (2016): Anthocyanin analyses of Vaccinium fruit dietary supplements. –Food Sci.Nutr. 4: 742752.

  • Lu, Q., Lv, S., Peng, Y., Zhu, Ch. and Pan, S. (2018): Characterization of phenolics and anti-oxidant abilities of red novel orange “Cara Cara” harvested from five regions of China. –Int. J. Food Prop. 21: 11071116.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Marin, P. D., Veitch, N. C., Grayer, R. J., Kite, G. C., Soković, M. and Janacković, P. (2007): Flavonoids from Phlomis fruticosa (Lamiaceae) growing in Montenegro. –Biochem. Syst. Ecol. 35: 462466.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Marwat, S. K., UR-Rehman, F., Shoaib Khan, M., Ghulam, S., Anwar, N., Mustafa, G. H. and Usman, K. H. (2011): Phytochemical constituents and pharmacological activities of sweet basil, Ocimum basilicum L. (Lamiaceae).–Asian J. Chem. 23: 37733782.

    • Search Google Scholar
    • Export Citation
  • Mena, P., Cirlini, M., Tassotti, M., Herrlinger, K. A., Dall’Asta, C. and Del Rio, D. (2016): Phytochemical profiling of flavonoids, phenolic acids, terpenoids, and volatile fraction of a rosemary (Rosmarinus officinalis L.) extract. –Molecules 21: 115.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Mihailović, V., Katanić Stanković, J. S. and Mihailović, N. (2020): Phenolic compounds diversity of Teucrium species. – In: Stanković, M. (ed.): Teucrium species: biology and applications. Springer Nature, Switzerland, pp. 143177.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Milošević-Djordjević, O., Radović Jakovljević, M., Marković, A., Stanković, M., Ćirić, A., Marinković, D. and Grujičić, D. (2018): Polyphenolic contents of Teucrium polium L. and Teucrium scordium L. associated with their protective effects against MMC-induced chromosomal damage in cultured human peripheral blood lymphocytes. –Turk. J. Biol. 42: 152162.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Mitreski, I., Stanoeva, J. P., Stefova, M., Stefkov, G. and Kulevanova, S. (2014): Polyphenols in representative Teucrium species in the flora of R. Macedonia: LC/DAD/ESI-MSn profile and content.–Nat. Prod. Comm. 9: 175180.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Napoli, E., Siracusa, L. and Ruberto, G. (2020): New tricks for old guys: recent developments in the chemistry, biochemistry, applications and exploitation of selected species from the Lamiaceae family. –Chem. Biodiv. 17: 153.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Nastić, N., Švarc-Gajić, J., Delerue-Matos, C., Morais, S., Barroso, M. F. and Moreira, M. M. (2018): Subcritical water extraction of antioxidants from mountain germander (Teucrium montanum L.). –J. Supercrit. Fluids 138: 200206.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Navarro, T. (2020). Systematic and biogeography of the genus Teucrium (Lamiaceae). – In: Stanković, M. (ed.): Teucrium species: biology and applications. Springer Nature, Switzerland, pp. 138.

    • Search Google Scholar
    • Export Citation
  • Noor Hashim, N. H., Maulidiani, M., Mediani, A. and Abas, F. (2018): Chemical profile of xanthine oxidase inhibitor fraction of Persicaria hydropiper. –Int. Food Res. J. 25: 10881094.

    • Search Google Scholar
    • Export Citation
  • Ordaz, J. J., Hernandez, J. M., Ramirez-Godinez, J., Castaneda-Ovando, A., Gonzalez-Olivares, L. G. and Contreras-Lopez, E. (2018): Bioactive compounds in aqueous extracts of lemon balm (Melissa officinalis) cultivated in Mexico. –Arch. Latinoamer. Nutr. 68: 268279.

    • Search Google Scholar
    • Export Citation
  • Ozcan, T. (2020). Morphological characteristics of Teucrium species: vegetative morphology. – In: Stanković, M. (ed.): Teucrium species: biology and applications. Springer Nature, Switzerland, pp. 3951.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Özer, Z., Kılıç, T., Çarıkçı, S. and Yilmaz, H. (2018): Investigation of phenolic compounds and antioxidant activity of Teucrium polium L. decoction and infusion. –J. BAUN Inst. Sci. Technol. 20: 212218.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Patonay, K., Korózs, M., Murányi, Z. and Pénzesné Kónya, E. (2017): Polyphenols in northern Hungarian Mentha longifolia (L.) L. treated with ultrasonic extraction for potential oenological uses. –Turk. J. Agr. For. 41: 208217.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Pereira, V. V., da Fonseca, F. A., Bento, C. S. O., Oliveira, P. M., Rocha, L. L., Augusti, R., Mendonca Filho, C. V. and Silva, R. R. (2015): Electrospray ionization mass spec-trometry fingerprint of the Byrsonima species. –Rev. Virtual Quim. 7: 25392548.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Pourhosseini, S. H., Mirjalili, M. H., Nejad Ebrahimi, S. and Sonboli, A. (2018): Essential oil quantity and quality of different plant organs from Perovskia abrotanoides Karel in natural habitat of north Khorasan province.–Plant Prod. 40: 5364.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Pratima, N. A. and Gadikar, R. (2018): Liquid chromatography-mass spectrometry and its applications: a brief review. –Arch. Org. Inorg. Chem. Sci. 1: 2634.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Quesadaa, L., Arecheb, C., Astudilloa, L., Gutierreza, M., Sepulvedac, B. and San-Martin, A. (2012): Biological activity of isoflavonoids from Azorella madreporica. –Nat. Prod. Comm. 7: 11871188.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Rechinger, K. H. (1982): Teucrium L. – In: Rechinger, K. H. (ed): Flora Iranica. Vol. 150. Akademische Druck-U. Verlagsanstalt, Graz, pp. 2344.

    • Search Google Scholar
    • Export Citation
  • Reed, K. A. (2009): Identification of phenolic compounds from peanut skin using HPLC-MSn. – Dissertation, Virginia Polytechnic Institute and State University, 390 pp.

    • Search Google Scholar
    • Export Citation
  • Rios, L. J., Francini, F. and Schinella, G. R. (2015): Natural products for the treatment of type 2 diabetes mellitus.–Planta Med. 81: 975994.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Sadeghi, H., Jamalpoor, S. and Shirzadi, M. H. (2014): Variability in essential oil of Teucrium polium L. of different latitudinal populations. –Ind. Crops Prod. 54: 130134.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Santos, R. T., Hiramoto, L. L., Lago, J. H. G., Sartorelli, P., Tempone, A. G., Pinto, E. G. and Lorenzi, H. (2012): Anti-trypanosomal activity of 1,2,3,4,6-penta-O-galloyl-b-Dglucose isolated from Plectranthus barbatus Andrews (Lamiaceae). –Quim. Nova. 35: 22292232.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Sena Filho, J. G., Barreto, I. C., Soares Filho, A. O., Nogueira, P. C. L., Teodoro, A. V., Cruz da Silva, A. V., Xavier, H. S., Rabbani, A. R. C., Spakowicz, D. J. and Duringer, J. M. (2017): Volatile metabolomic composition of Vitex species: chemodiversity insights and acaricidal activity. –Front. Plant Sci. 8: 19 (Art. 1931)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Shin, H. S., Bae, M.-J., Jung, S. Y. and Shon, D.-H. (2013): Inhibitory effect of skullcap (Scutellaria baicalensis) extract on ovalbumin permeation in vitro and in vivo.–Food Chem. 140: 2230.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Singh, B., Singh, D. and Goel, R. K. (2012): Dual protective effect of Passiflora incarnate in epilepsy and associated postictal depression. –J. Ethnopharmacol. 139: 273279.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Sobeh, M., ElHawary, E., Peixoto, H., Labib, R. M., Handoussa, H., Swilam, N., El-Khatib, A. A., Sharapov, F., Mohamed, T., Krstin, S., Linscheid, M. W., Singab, A. N., Wink, M. and Ayoub, N. (2016): Identification of phenolic secondary metabolites from Schotia brachypetala Sond. (Fabaceae) and demonstration of their antioxidant activities in Caenorhabditis elegans.–PeerJ 4:e2404

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Stefkov, G., Karapandzova, M., Stefova, M., Bankova, V. and Kulevanova, S. (2012): HPLC and UV-spectrophotometry analysis of flavonoids in spray-dried and freeze-dried extracts of Teucrium polium L. (Lamiaceae). –Maced. Pharm. Bull. 58: 3944.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Štulíková, K., Karabin, M., Nešpor, J. and Dostálek, P. (2018): Therapeutic perspectives of 8-prenylnaringenin, a potent phytoestrogen from hops.–Molecules 23: 113 (Art. 660) .

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Szymborska-Sandhu, I., Przybył, J. L., Pióro-Jabrucka, E., Jędrzejuk, A., Węglarz, Z. and Bączek, K. (2020): Effect of shading on development, yield and quality of bastard balm herb (Melittis melissophyllum L.).–Molecules 25: 213 (Art. 2142)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Taamalli, A., Arráez-Román, D., Abaza, L., Iswaldi, I., Fernandez-Gutiérrez, A., Zarrouka, M. and Segura-Carretero, A. (2015): LC-MS-based metabolite profiling of methanolic extracts from the medicinal and aromatic species Mentha pulegium and Origanum majorana. –Phytochem. Anal. 26: 320330.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Tykheev, Zh. A., Zhigzhitzhapova, S. V., Zhang, F., Taraskin, V. V., Anenkhonov, O. A., Radnaeva, L. D. and Chen, Sh. (2018): Constituents of essential oil and lipid fraction from the aerial part of Bupleurum scorzonerifolium Willd. (Apiaceae) from different habitats.–Molecules. 23: 116 (Art. 1496)

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Tzima, K., Brunton, N. P. and Rai, D. K. (2018): Qualitative and quantitative analysis of polyphenols in Lamiaceae plants: a review. –Plants 7: 2555.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Uritu, C. M., Mihai, C. T., Stanciu, G. D., Dodi, G., Alexa-Stratulat, T., Luca, A., Leon-Constantin, M. M., Stefanescu, R., Bild, V., Melnic, S. and Tamb, B. I. (2018): Medicinal plants of the family Lamiaceae in pain therapy: a review. –Pain Res.Manage. 2018: 145.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Ur Rehman, N., Al Sahai, J. M. S., Hussain, H., Khan, A. L., Gilan, S. A., Abbas, G., Hussain, J., Sabahi, J. N. and Al-Harrasi, A. (2014): Phytochemical and pharmacological investigation of Teucrium muscatense. –Int. J. Phytomed. 8: 567579.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Van Wyk, B.-E. and Gorelik, B. (2017): The history and ethnobotany of Cape herbal teas. –S. Afr. J. Bot. 110: 1838.

  • Vlase, L., Benedec, D., Hanganu, D., Damian, G., Csillag, I., Sevastre, B., Mot, A. C., SilaghiDumitrescu, R. and Tilea, L. (2014): Evaluation of antioxidant and antimicrobial activities and phenolic profile for Hyssopus officinalis, Ocimum basilicum and Teucrium chamaedrys.–Molecules 19: 54905507.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Venditti, A., Frezza, C., Majd Zadeh, S. M., Foddai, S., Serafini, M. and Bianco, A. (2017): Secondary metabolites from Teucrium polium L. collected in Southern Iran. –Arab. J. Med. Aromat. Plants 3: 108123.

    • Search Google Scholar
    • Export Citation
  • Yang, R., Yuan, B. Ch., Ma, Y. Sh., Zhou, Sh. and Liu, Y. (2017): The anti-inflammatory activity of licorice, a widely used Chinese herb. –Pharm. Biol. 55: 518.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • Zhang, H., Wang, K., Wua, J., Chena, Y. and Hea, P. (2011): A new flavonoid glycoside from Vaccaria hispanica. –Nat. Prod. Comm. 6: 15991602.

    • Crossref
    • Search Google Scholar
    • Export Citation
  • http://mona.fiehnlab.ucdavis.edu. Accessed 12 December 2018

  • http://massbank.eu. Accessed 27 November 2012

  • http://pubchem.ncbi.nlm.nih.gov. Accessed 22 September 2015

 

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Botta-Dukát, Zoltán
E-mail: botta-dukat.zoltan@okologia.mta.hu

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Lőkös, László
E-mail: acta@bot.nhmus.hu
Institute: Botanical Department, Hungarian Natural History Museum
Address: Könyves K. krt. 40. H-1097 Budapest, Hungary

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Scimago  
Scimago
H-index
23
Scimago
Journal Rank
0,392
Scimago Quartile Score Plant Science (Q2)
Ecology, Evolution, Behavior and Systematics (Q3)
Scopus  
Scopus
Cite Score
2,5
Scopus
CIte Score Rank
Plant Science 205/482 (Q2)
Ecology, Evolution, Behavior and Systematics 322/687 (Q2)
Scopus
SNIP
1,046

2020  
Scimago
H-index
19
Scimago
Journal Rank
0,417
Scimago
Quartile Score
Plant Science Q2
Ecology, Evolution, Behavior and Systematics Q3
Scopus
Cite Score
155/89=1,7
Scopus
Cite Score Rank
Plant Science 221/445 (Q2)
Ecology, Evolution, Behavior and Systematics 374/647 (Q3)
Scopus
SNIP
0,838
Scopus
Cites
260
Scopus
Documents
22
Days from submission to acceptance 127
Days from acceptance to publication 132
Acceptance
Rate
36%

 

2019  
Scimago
H-index
17
Scimago
Journal Rank
0,404
Scimago
Quartile Score
Plant Science Q2
Ecology, Evolution, Behavior and Systematics Q3
Scopus
Cite Score
164/91=1,8
Scopus
Cite Score Rank
Plant Science 209/431 (Q2)
Ecology, Evolution, Behavior and Systematics 358/629 (Q3)
Scopus
SNIP
0,699
Scopus
Cites
215
Scopus
Documents
23
Acceptance
Rate
30%

 

Acta Botanica Hungarica
Publication Model Hybrid
Submission Fee none
Article Processing Charge 900EUR/article
Printed Color Illustrations 40 EUR (or 10 000 HUF) + VAT / piece
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription fee 2022 Online subsscription: 594 EUR / 740 USD
Print + online subscription: 676 EUR / 844 USD
Subscription fee 2023 Online subsscription: 612 EUR / 740 USD
Print + online subscription: 696 EUR / 844 USD
Subscription Information Online subscribers are entitled access to all back issues published by Akadémiai Kiadó for each title for the duration of the subscription, as well as Online First content for the subscribed content.
Purchase per Title Individual articles are sold on the displayed price.

Acta Botanica Hungarica
Language English
French
German
Russian
Spanish
Size B5
Year of
Foundation
1954
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-6495 (Print)
ISSN 1588-2578 (Online)

 

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