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  • 1 Department of Nutrition, Szent István University H-2103 Gödöllő, Páter K. u. 1, Hungary
  • | 2 “Szent István” University, Department of Nutrition Gödöllő, Hungary
  • | 3 Institute for Small Animal Breeding and Nutrition Gödöllő, Hungary
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Glutathione peroxidase enzyme superfamily plays significant role in the elimination of reactive oxygen free radicals in the animals. Many characteristics of these proteins have been revealed already, but their regulation is still not known. Several data suggest that some environmental factors have certain regulatory effect, while others propose strict genetic regulation.In this report we present four different environmental induction models in which New Zealand white rabbits were used as experimental animals. In three models, free radical load of different origin, lipidperoxide load, application of a glutathione depletor or a prooxidant agent, was introduced. Beside these negative models a positive model was also constructed in which additive selenium was supplied.Glutathione peroxidase activity was measured in blood serum, erythrocyte haemolysate and liver. Reduced glutathione, and malondialdehyde concentration in the liver were also determined.According to the results, the established models are capable for analysing the enzyme activity´environmental interactions.

  • Toronsco P, Smok G, Videla LA: Potentation of ischemia-reperfusion liver injury by hyperthyroidism in rat. Free Radic. Bio. Med. 23, 19-25 (1997)

    'Potentation of ischemia-reperfusion liver injury by hyperthyroidism in rat ' () 23 Free Radic. Bio. Med. : 19 -25.

    • Search Google Scholar
  • Weichselbaum TE: An accurate and rapid method for the determination of protein in small amounts of serum and plasma. Am. J. Clin. Pathol. 16, 40-43 (1946)

    'An accurate and rapid method for the determination of protein in small amounts of serum and plasma ' () 16 Am. J. Clin. Pathol. : 40 -43.

    • Search Google Scholar
  • Whanger P, Vendeland S, Park YC, Xia Y: Metabolism of subtoxic levels of selenium in animals and humans. Ann. Clin. Lab. Sci. 26, 88-113 (1996)

    'Metabolism of subtoxic levels of selenium in animals and humans ' () 26 Ann. Clin. Lab. Sci. : 88 -113.

    • Search Google Scholar
  • Zamorski R, Borowska K, Kopper J (1995): Selenium, zinc and magnesium content and glutathione peroxidase activity in blood of humans and some animal species. In: Proc. Mengen- und Spurenelementen 15. Arbeitstagung, Friedrich Schiller Universitat, Jena, pp. 421-427.

    Selenium, zinc and magnesium content and glutathione peroxidase activity in blood of humans and some animal species , () 421 -427.

    • Search Google Scholar
  • Placer ZA, Cusham LL, Johnson BC: Estimation of product of lipid peroxidation (malonyl dialdehyde) in biochemical systems. Anal. Biochem. 16, 359-364 (1966)

    'Estimation of product of lipid peroxidation (malonyl dialdehyde) in biochemical systems ' () 16 Anal. Biochem. : 359 -364.

    • Search Google Scholar
  • Sedlak J, Lindsay RHC: Estimation of total, protein bound and non-protein sulfhydryl groups in tissue with Ellmann's reagent. Anal. Biochem. 25, 192-205 (1968)

    'Estimation of total, protein bound and non-protein sulfhydryl groups in tissue with Ellmann's reagent ' () 25 Anal. Biochem. : 192 -205.

    • Search Google Scholar
  • Suchocka Z, Kobylinska K, Pachecka J: Activity of glutathione-dependent enzymes in long term diabetes. I. Activity of glutathione-S-transferase and glutathione peroxidase in the liver of alloxan induced diabetic rats. Acta Pol. Pharm. 52, 207-211 (1995)

    'Activity of glutathione-dependent enzymes in long term diabetes. I. Activity of glutathione-S-transferase and glutathione peroxidase in the liver of alloxan induced diabetic rats ' () 52 Acta Pol. Pharm. : 207 -211.

    • Search Google Scholar
  • Clausen J, Nielsen SA: Comparison of whole blood selenium values and erythrocyte glutathione peroxidase activities of normal individuals on supplementation with selenate, selenite, L-methionine and high selenium yeast. Biol. Trace Elem. Res. 15, 125-138 (1988)

    'Comparison of whole blood selenium values and erythrocyte glutathione peroxidase activities of normal individuals on supplementation with selenate, selenite, L-methionine and high selenium yeast ' () 15 Biol. Trace Elem. Res. : 125 -138.

    • Search Google Scholar
  • Gaál T (1998): Glutathione peroxidase activity and selenium status. In: Role of selenium in the environment and health, eds: Cser M, Sziklainé László I (In Hungarian) FRAG Bt. Budapest

    Glutathione peroxidase activity and selenium status , ().

  • Humaloja T, Mykkanen HM: Intestinal absorption of 75Se-labeled sodium selenite and selenomethionine in chicks: effects of time, segment, selenium concentration and method of measurement. J. Nutr. 116, 142-148 (1986)

    'Intestinal absorption of 75Se-labeled sodium selenite and selenomethionine in chicks: effects of time, segment, selenium concentration and method of measurement ' () 116 J. Nutr. : 142 -148.

    • Search Google Scholar
  • Lawrence RA, Burk RF: Glutathione peroxidase activity in selenium deficient rat liver. Biochem. Biophys. Res. Comm. 71, 952 (1976)

    'Glutathione peroxidase activity in selenium deficient rat liver ' () 71 Biochem. Biophys. Res. Comm. : 952.

    • Search Google Scholar
  • Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275 (1951)

    'Protein measurement with the Folin phenol reagent ' () 193 J. Biol. Chem. : 265 -275.

  • Meister A, Anderson ME: Glutathione. Annu. Rev. Biochem. 52, 711-760 (1983)

    'Glutathione ' () 52 Annu. Rev. Biochem. : 711 -760.

  • Mézes M, Virág Gy, Barta M, Abouzeid AD: Effect of lipid peroxide loading on lipid peroxidation and on the glutathione and cytochrome systems in rabbits. Acta Vet. Hung. 44, 443-450 (1996)

    'Effect of lipid peroxide loading on lipid peroxidation and on the glutathione and cytochrome systems in rabbits ' () 44 Acta Vet. Hung. : 443 -450.

    • Search Google Scholar
  • Mézes M, Virág Gy, Barta M, Erdélyi M: Effect of nutritional and genetic factors on glutathione peroxidase in rabbit. Curr. Top. Biophys. 22, 154-157 (1998)

    'Effect of nutritional and genetic factors on glutathione peroxidase in rabbit ' () 22 Curr. Top. Biophys. : 154 -157.

    • Search Google Scholar
  • Monks TJ, Lau SS: Activation and detoxification of bromobenzene in extrahepatic tissues. Life Sci. 35, 561-568 (1984)

    'Activation and detoxification of bromobenzene in extrahepatic tissues ' () 35 Life Sci. : 561 -568.

    • Search Google Scholar
  • Avissar N, Slemmon JR, Palmer IS, Cohen HJ: Partial sequence of human plasma glutathione peroxidase and immunologic identification of milk glutathione peroxidase as the plasma enzyme. J.Nutr. 121, 1243-1249(1991)

    'Partial sequence of human plasma glutathione peroxidase and immunologic identification of milk glutathione peroxidase as the plasma enzyme ' () 121 J.Nutr. : 1243 -1249.

    • Search Google Scholar
  • Arai T, Sugawara M, Sako T, Motoyoshi S, Shimura T, Tsutsui N. Konno T: Glutathione peroxidase activity in tissues of chickens supplemented with dietary selenium. Comp. Biochem. Physiol. 107A, 245-248 (1994)

    'Glutathione peroxidase activity in tissues of chickens supplemented with dietary selenium ' () 107A Comp. Biochem. Physiol. : 245 -248.

    • Search Google Scholar

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Senior editors

Editor(s)-in-Chief: Rosivall, László

Honorary Editor(s)-in-Chief): Monos, Emil

Managing Editor(s): Bartha, Jenő; Berhidi, Anna

Co-editor(s): Koller, Ákos; Lénárd, László; Szénási, Gábor

Assistant Editor(s): G. Dörnyei (Budapest), Zs. Miklós (Budapest), Gy. Nádasy (Budapest)

Hungarian Editorial Board

      Benedek, György (Szeged)
      Benyó, Zoltán (Budapest)
      Boros, Mihály (Szeged)
      Chernoch, László (Debrecen)
      Détári, László (Budapest)
      Hamar, János (Budapest)
      Hantos, Zoltán (Szeged)
      Hunyady, László (Budapest)
      Imre, Sándor (Debrecen)
      Jancsó, Gábor (Szeged)
      Karádi, Zoltán (Pécs)
      Kovács, László (Debrecen)
      Palkovits, Miklós (Budapest)
      Papp, Gyula (Szeged)
      Pavlik, Gábor (Budapest)
      Spät, András (Budapest)
      Szabó, Gyula (Szeged)
      Szelényi, Zoltán (Pécs)
      Szolcsányi, János (Pécs)
      Szollár, Lajos (Budapest)
      Szücs, Géza (Debrecen)
      Telegdy, Gyula (Szeged)
      Toldi, József (Szeged)
      Tósaki, Árpád (Debrecen)

International Editorial Board

      R. Bauer (Jena)
      W. Benjelloun (Rabat)
      A. W. Cowley Jr. (Milwaukee)
      D. Djuric (Belgrade)
      C. Fry (London)
      S. Greenwald (London)
      O. Hänninen (Kuopio)
      H. G. Hinghofer-Szalkay (Graz)
      Th. Kenner (Graz)
      Gy. Kunos (Richmond)
      M. Mahmoudian (Tehran)
      T. Mano (Seki, Gifu)
      G. Navar (New Orleans)
      H. Nishino (Nagoya)
      O. Petersen (Liverpool)
      U. Pohl (Münich)
      R. S. Reneman (Maastricht)
      A. Romanovsky (Phoenix)
      G. M. Rubanyi (Richmond)
      T. Sakata (Oita)
      A. Siddiqui (Karachi)
      Cs. Szabo (Beverly)
      E. Vicaut (Paris)
      N. Westerhof (Amsterdam)
      L. F. Zhang (Xi'an)

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Editorial Correspondence:
Acta Physiologica Hungarica
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Acta Physiologica Hungarica
Language English
Size  
Year of
Foundation
1950
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0231-424X (Print)
ISSN 1588-2683 (Online)

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