View More View Less
  • 1 Budapest University of Technology and Economics Budapest
  • | 2 Széchenyi University of Győr Győr, Hungary
  • | 3 Budapest University of Technology and Economics Budapest
  • | 4 Department of Control Engineering and Information Technology, Budapest University of Technology and Economics H-1117 Budapest, Magyar Tudósok krt. 2, Hungary
Restricted access

Purchase article

USD  $25.00

1 year subscription (Individual Only)

USD  $752.00

In this case study a fully symbolic design and modeling method are presented for blood glucose control of diabetic patients under intensive care using Mathematica. The analysis is based on a modified two-compartment model proposed by Bergman et al. (2). The applied feedback control law decoupling even the nonlinear model leads to a fully symbolic solution of the closed loop equations. The effectivity of the applied symbolic procedures being mostly built-in the new version of Control System Professional Suite (CSPS) Application of Mathematica have been demonstrated for controller design in case of a glucose control for treatment of diabetes mellitus and also presented for a numerical situation described in Juhász (8). The results are in good agreement with the earlier presented symbolic-numeric analysis by Benyó et al. (1).

  • Benyó Z, Paláncz B, Juhász Cs, Várady P: Design of Glucose Control via Symbolic Computation. Proc. of the 20th Ann. Internat. Conf. of the IEEE Eng. in Medicine and Biology Society. 20/6, 3116-3119 (1998)

    'Design of Glucose Control via Symbolic Computation ' () 20/6 Proc. of the 20th Ann. Internat. Conf. of the IEEE Eng. in Medicine and Biology Society : 3116 -3119.

    • Search Google Scholar
  • Bergman BN, Ider YZ, Bowden CR, Cobelli C: Quantitive estimation of insulin sensitivity. Am. J. Physiol. 236, 667-677 (1979)

    'Quantitive estimation of insulin sensitivity ' () 236 Am. J. Physiol. : 667 -677.

  • Sano A: Adaptive and optimal schemes for control of blood glucose levels. Biomedical Measurements, Informatics and Control. 1/1, 16-22 (1986)

    'Adaptive and optimal schemes for control of blood glucose levels ' () 1/1 Biomedical Measurements, Informatics and Control. : 16 -22.

    • Search Google Scholar
  • Juhász CS: Medical Application of Adaptive Control, Supporting Insulin-Therapy in case of Diabetes Mellitus. PhD thesis, Budapest (1993)

  • Benett DL, Gourley SA: Asymptotic properties of a delay differential equation for the interaction of glucose with plasma and interstitial insulin. Elsevier, Applied Mathematics and Computation, In Press (2003)

    Asymptotic properties of a delay differential equation for the interaction of glucose with plasma and interstitial insulin , ().

    • Search Google Scholar
  • Mukhopadhyay A, De Gaetano A, Arino O: Modelling the Intra-Venous Glucose Tolerance Test: a global study for a single-distributed-delay model. American Institute of Mathematical Sciences, Discrete and Continuous Dynamical Systems-Series B, 4/2, 407-417 (2004)

    'Modelling the Intra-Venous Glucose Tolerance Test: a global study for a single-distributed-delay model ' () 4/2 American Institute of Mathematical Sciences, Discrete and Continuous Dynamical Systems-Series B : 407 -417.

    • Search Google Scholar
  • Candas B, Radziuk J: An adaptive controller of glycemia based on a physiological model of insulin-dependent glucose removal. Ann. Internat Conf. of the IEEE Eng. in Medicine and Biology Society. 13/5, 2285-2286 (1991)

    'An adaptive controller of glycemia based on a physiological model of insulin-dependent glucose removal ' () 13/5 Ann. Internat Conf. of the IEEE Eng. in Medicine and Biology Society : 2285 -2286.

    • Search Google Scholar
  • Fischer ME, Teo KL: Optimal Insulin Infusion Resulting from a Mathematical Model of Blood Glucose Dynamics. IEEE Transactions on Biomedical Engineering, 36, No. 3, 479-486 (1989)

    'Optimal Insulin Infusion Resulting from a Mathematical Model of Blood Glucose Dynamics ' () 36 IEEE Transactions on Biomedical Engineering : 479 -486.

    • Search Google Scholar
  • Juhász C, Asztalos B, Adasdi M: An Adaptive Control Approach to Diabetic Management. Innovation et Technologie, Biologie et Medicine. 17/1 (1996)

    'An Adaptive Control Approach to Diabetic Management ' () 17/1 Innovation et Technologie, Biologie et Medicine .

    • Search Google Scholar
  • Ogunye AB: Process Control and Symbolic Computation: An Overview with Maple V. Maple Tech. 3/1, 94-103 (1996)

    'Process Control and Symbolic Computation: An Overview with Maple V ' () 3/1 Maple Tech. : 94 -103.

    • Search Google Scholar

The author instruction is available in PDF.

Please, download the file from HERE

Senior editors

Editor(s)-in-Chief: Rosivall, László

Honorary Editor(s)-in-Chief): Monos, Emil

Managing Editor(s): Bartha, Jenő; Berhidi, Anna

Co-editor(s): Koller, Ákos; Lénárd, László; Szénási, Gábor

Assistant Editor(s): G. Dörnyei (Budapest), Zs. Miklós (Budapest), Gy. Nádasy (Budapest)

Hungarian Editorial Board

      Benedek, György (Szeged)
      Benyó, Zoltán (Budapest)
      Boros, Mihály (Szeged)
      Chernoch, László (Debrecen)
      Détári, László (Budapest)
      Hamar, János (Budapest)
      Hantos, Zoltán (Szeged)
      Hunyady, László (Budapest)
      Imre, Sándor (Debrecen)
      Jancsó, Gábor (Szeged)
      Karádi, Zoltán (Pécs)
      Kovács, László (Debrecen)
      Palkovits, Miklós (Budapest)
      Papp, Gyula (Szeged)
      Pavlik, Gábor (Budapest)
      Spät, András (Budapest)
      Szabó, Gyula (Szeged)
      Szelényi, Zoltán (Pécs)
      Szolcsányi, János (Pécs)
      Szollár, Lajos (Budapest)
      Szücs, Géza (Debrecen)
      Telegdy, Gyula (Szeged)
      Toldi, József (Szeged)
      Tósaki, Árpád (Debrecen)

International Editorial Board

      R. Bauer (Jena)
      W. Benjelloun (Rabat)
      A. W. Cowley Jr. (Milwaukee)
      D. Djuric (Belgrade)
      C. Fry (London)
      S. Greenwald (London)
      O. Hänninen (Kuopio)
      H. G. Hinghofer-Szalkay (Graz)
      Th. Kenner (Graz)
      Gy. Kunos (Richmond)
      M. Mahmoudian (Tehran)
      T. Mano (Seki, Gifu)
      G. Navar (New Orleans)
      H. Nishino (Nagoya)
      O. Petersen (Liverpool)
      U. Pohl (Münich)
      R. S. Reneman (Maastricht)
      A. Romanovsky (Phoenix)
      G. M. Rubanyi (Richmond)
      T. Sakata (Oita)
      A. Siddiqui (Karachi)
      Cs. Szabo (Beverly)
      E. Vicaut (Paris)
      N. Westerhof (Amsterdam)
      L. F. Zhang (Xi'an)

Editorial Office:
Akadémiai Kiadó Zrt.
Prielle Kornélia u. 21–35, H-1117 Budapest, Hungary

Editorial Correspondence:
Acta Physiologica Hungarica
Semmelweis University, Faculty of Medicine Institute of Pathophysiology
Nagyvárad tér 4, H-1089 Budapest, Hungary
Phone/Fax: +36-1-2100-100
E-mail: aph@semmelweis-univ.hu

Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • Chemical Abstracts
  • EMBASE/Excerpta Medica
  • Global Health
  • Index Copernicus
  • Index Medicus
  • Medline
  • Referativnyi Zhurnal
  • Science Citation Index Expanded
  • SCOPUS

 

Acta Physiologica Hungarica
Language English
Size  
Year of
Foundation
1950
Publication
Programme
changed title
Volumes
per Year
 
Issues
per Year
 
Founder Magyar Tudományos Akadémia
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0231-424X (Print)
ISSN 1588-2683 (Online)

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Feb 2021 0 1 1
Mar 2021 7 0 0
Apr 2021 5 0 0
May 2021 2 0 0
Jun 2021 0 0 0
Jul 2021 2 2 2
Aug 2021 0 0 0