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  • 1 Virginia Commonwealth University Department of Internal Medicine, Division of Cardiology Richmond VA 23298-0281 USA
  • 2 University of Mary Washington Department of Biology Fredericksburg VA 22401 USA
  • 3 Virginia Commonwealth University Division of Cardiology Box 980281 1101 East Marshall Street, Room 7-046 Richmond VA 23298 USA
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Myocyte loss due to ischemia/reperfusion injury leads to cardiac dysfunction and heart failure, and the concentration of current therapy is limited on preventing the progression. Recent interest has focused on transplantation of stem cells to differentiate and replenish the loss of myocytes. Adipose tissue represents an alternative and abundant source of adult stem cells with the ability to differentiate along multiple lineage pathways. Recent studies have demonstrated the potential of adipose tissue-derived stem cells for treatment of acute myocardial infarction. The aim of this review is to discuss the potential therapeutic benefits of adipose tissue-derived stem cells in improving cardiac function post-injury.

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