The commercial cultivation of Phyllanthus amarus (Schum and Thonn) has led to the outbreak of stem blight caused by Corynespora cassiicola (Berk and Curt) Wei. Infection of C. cassiicola is reported on P. amarus for the first time. C. cassiicola produced glycoproteinaceous toxin responsible for the symptoms simirlarly produced by the pathogen. B. subtilis (CBE4), P. chlororaphis (PA23), endophytic P. fluorescens (ENPF1) and T. viride (Tv-MNT7) degraded the toxin of C. cassiicola.