In this article, an attempt has been made to present the life, extraordinary professional carrier and ramifying activity of Mihail Lomonosov, one of the most brilliant encyclopedic minds of the eighteenth-century Europe. The study is primarily focused on the research activity of Lomonosov but it also gives account of his personality and behavior. The author emphasizes Lomonosov's outstanding achievements in various branches of sciences and humanities. The present publication is specially relevant due to the two hundred fiftieth anniversary of the Moscow State University which is the most durable and fascinating creation of Lomonosov. In the final paragraphs, the author indicates those contemporaneous Hungarian scholars who were familiar with Lomonosov's works published in Latin and German.