Anthocyanin composition and profile were analysed in skin extracts from red grapes and wines of the autochthonous Croatian cultivars of Babić and Plavac mali by HPLC-DAD-MS method. Higher relative abundance of malvidin-3-monoglucoside and lower relative abundance of peonidin-3-monoglucoside and cyanidin-3-monoglucoside were identified in wine in relation to their earlier abundance in grapes. Using principal component analysis (PCA), the wine samples showed differences between wine types, although the grape samples did not show any considerable differences concerning the anthocyanin composition. The main differences between Babić and Plavac mali wines were detected in a monoglucoside acetate (malvidin-3-monoglucoside acetate), a monoglucoside-caffeoate (malvidin-3-monoglucoside caffeoate) and a group of monoglucosides (malvidin-3-monoglucoside, delphinidin-3-monoglucoside, petunidin-3-monoglucoside and peonidin-3-monoglucoside).