Forage plants may become contaminated by mycotoxins already on the cropland as a result of mould infection, the degree of which can be diminished by the use of appropriate agrotechnical methods or resistant plant cultivars. During storage, the main goal is to prevent further mould infection and mycotoxin contamination. In that period, the moisture content of feedstuffs and the mould contamination of storage spaces, which can be minimised by the use of fungicidal products, are the most critical factors. Feed manufacturing processes do not substantially decrease the mycotoxin content of feedstuffs, and the efficiency of the recommended chemical and/or heat treatment procedures is also questionable as they are expensive and may reduce the nutrient content. To minimise the adverse effects of mycotoxins on animals, the use of products capable of binding and biologically transforming mycotoxins is also recommended; however, such products have varying efficacy.
Balzer, A., Tardieu, D., Bailly, J.D. & Guerre, P. (2004): The trichothecenes: the nature of toxins, natural occurrence in foods and feeds and ways of combating their occurrence. Rev. Med. Vet., 155, 299–314.
Guerre P. , 'The trichothecenes: the nature of toxins, natural occurrence in foods and feeds and ways of combating their occurrence ' (2004 ) 155 Rev. Med. Vet. : 299 -314.
Binder, E.M. (2007): Managing the risk of mycotoxins in modern feed production. Anim. Feed Sci. Technol., 133, 149–166.
Binder E.M. , 'Managing the risk of mycotoxins in modern feed production ' (2007 ) 133 Anim. Feed Sci. Technol. : 149 -166.
Bondy, G.S. & Pestka, J.J. (2000): Immunomodulation by fungal toxins. J. Toxicol. Environ. Health part B, 3, 109–143.
Pestka J.J. , 'Immunomodulation by fungal toxins ' (2000 ) 3 J. Toxicol. Environ. Health part B : 109 -143.
Boudra, H. & Morgavi, D.P. (2009): Silage could be a way to detoxify maize contaminated by mycotoxins. Proceedings. ISM Conference 2009. Tulln, p. 106.
Boutrif, E. & Canet, C. (1998): Mycotoxin prevention and control: FAO programmes. Rev. Méd. Vét., 149, 681–694.
Canet C. , 'Mycotoxin prevention and control: FAO programmes ' (1998 ) 149 Rev. Méd. Vét. : 681 -694.
Breinholt, V., Arbogast, D., Loveland, P., Pereira, C., Dashwood, R., Hendricks, J. & Bailey, G. (1999): Chlorophyllin chemoprevention in trout initiated by aflatoxin B1 bath treatment: an evaluation of reduced bioavailability vs. target organ protective mechanisms. Toxicol. Appl. Pharmacol., 158, 141–151.
Bailey G. , 'Chlorophyllin chemoprevention in trout initiated by aflatoxin B1 bath treatment: an evaluation of reduced bioavailability vs. target organ protective mechanisms ' (1999 ) 158 Toxicol. Appl. Pharmacol. : 141 -151.
Cahagnier, B., Melcion, D. & Richard-Molard, D. (1995): Growth of Fusarium moniliforme and its biosynthesis of fumonisin B1 on maize grain as a function of different water activities. Lett. Appl. Microbiol., 20, 247–251.
Richard-Molard D. , 'Growth of Fusarium moniliforme and its biosynthesis of fumonisin B1 on maize grain as a function of different water activities ' (1995 ) 20 Lett. Appl. Microbiol. : 247 -251.
Campbell, B.C., Molyneux, R.J. & Schatzki, T.P. (2003): Current research on reducing pre- and postharvest aflatoxin contamination of US almond, pistachio and walnut. J. Toxicol. Toxin Rev., 22, 225–266.
Schatzki T.P. , 'Current research on reducing pre- and postharvest aflatoxin contamination of US almond, pistachio and walnut ' (2003 ) 22 J. Toxicol. Toxin Rev. : 225 -266.
Ciegler, A., Lillehoj, B., Peterson, R.E. & Hall, H.H. (1966): Microbial detoxification of aflatoxin. Appl. Microbiol., 14, 934–939.
Hall H.H. , 'Microbial detoxification of aflatoxin ' (1966 ) 14 Appl. Microbiol. : 934 -939.
Clevström, G., Möller, T., Göransson, B., Liljensjöö, A. & Ljunggren, H. (1989): Influence of formic acid on fungal flora of barley and on aflatoxin production in Aspergillus flavus Link. Mycopathologia, 107, 101–109.
Ljunggren H. , 'Influence of formic acid on fungal flora of barley and on aflatoxin production in Aspergillus flavus Link ' (1989 ) 107 Mycopathologia : 101 -109.
Codex Alimentarius Comm iss ion (2003): Code of practice for the prevention and reduction of mycotoxin contamination in cereals, including annexes on ochratoxin A, zearalenone, fumonisins and trichothecenes. CAC/RCP 51-2003 — http://www.codexalimentarius.net/download/standards/406/CXC_051e.pdf
Dobolyi, Cs., Sebők, F., Varga, J., Kocsubé, S., Szigeti, Gy., Baranyi, N., Szécsi, Á., Lustyik, Gy., Micsinai, A., Tóth, B., Varga, M., Kriszt, B. & Kukolya, J. (2011): Aflatoxin termelő Aspergillus flavus törzsek előfordulása hazai kukorica szemtermésben. (Occurrence of aflatoxin-producing Aspergillus flavus strains in maize kernels in Hungary.) Növényvédelem, 47, 125–133.
Kukolya J. , 'Aflatoxin termelő Aspergillus flavus törzsek előfordulása hazai kukorica szemtermésben ' (2011 ) 47 Növényvédelem : 125 -133.
Dupuy, J., Le Bars, P., Boudra, H. & Le Bars, J. (1993): Thermostability of fumonisin B1, a mycotoxin from Fusarium moniliforme, in corn. Appl. Environ. Microbiol., 159, 2864–2867.
Bars J. , 'Thermostability of fumonisin B1, a mycotoxin from Fusarium moniliforme, in corn ' (1993 ) 159 Appl. Environ. Microbiol. : 2864 -2867.
EC (2003): Regulation (EC) No 1831/2003 of the European Parliament and of the Council of 22 September 2003 on additives for use in animal nutrition. O.J. L 268.29.
EC (2006): Commission Recommendation of 17 August 2006 on the prevention and reduction of Fusarium toxins in cereals and cereal products (2006/583/EC). O.J. L 234.35.
EC (2009): Commission Regulation (EC) No 386/2009 of 12 May 2009 amending Regulation (EC) No 1831/2003 of the European Parliament and of the Council as regards the establishment of a new functional group of feed additives. O.J. L 118.66.
Farkas, J. & Beczner, J. (2009): A klímaváltozás és a globális felmelegedés várható hatása a mikológiai élelmiszerbiztonságra. (Effect of climate change and global warming on mycological food safety.) “Klíma-21” Füzetek, Klímaváltozás — Hatások — Válaszok. (56), 3–17.
Fazekas, B., Tóthné-Hajdú, E. & Tanyi, J. (2000): MYCO-AD hatása kísérletes T-2 toxikózis során brojlercsirkében. (Effect of MYCO-AD on experimentally-induced T-2 toxicosis in broiler chicken.) Magy. Állatorv. Lapja, 122, 412–416.
Tanyi J. , 'MYCO-AD hatása kísérletes T-2 toxikózis során brojlercsirkében ' (2000 ) 122 Magy. Állatorv. Lapja : 412 -416.
Ghosh, M.K., Chhabra, A., Atreja, P.P. & Chopra, R.C. (1996): Effect of treating with propionic acid, sodium bisulfite and sodium hydroxide on the biosynthesis of aflatoxin on groundnut cake. Anim. Feed Sci. Technol., 60, 43–49.
Chopra R.C. , 'Effect of treating with propionic acid, sodium bisulfite and sodium hydroxide on the biosynthesis of aflatoxin on groundnut cake ' (1996 ) 60 Anim. Feed Sci. Technol. : 43 -49.
Goldblatt, L.A. & Dollear, F.G. (1977): Detoxification of contaminated crops. -in: Rodricks, J.V., Hesseltine, C.W. & Mehlman, M.A. (Eds): Mycotoxins in human and animal health. Pathotox Publishers, Park Forrest South, pp. 139–150.
Dollear F.G. , '', in Mycotoxins in human and animal health , (1977 ) -.
Golob, P. (2007): On-farm mycotoxin control in food and feed grain. Good practices for animal feed and livestock 1. FAO, Rome, 27 pages.
Golob P. , '', in Good practices for animal feed and livestock 1 , (2007 ) -.
Herman, T.J. (2005): Quality assessment practices of feeds and feeding stuffs. American Soybean Association, Brussels, pp. 24–27.
Herman T.J. , '', in Quality assessment practices of feeds and feeding stuffs , (2005 ) -.
HGCA (2004): Drying and cooling grain: an update. Topic Sheet No. 78. Home Cereals Grain Authority, Kehilworth, U.K., p. 12.
'', in Drying and cooling grain: an update. Topic Sheet No. 78 , (2004 ) -.
Hofstetter, U., Schatzmayr, D. & Binder, E.M. (2005): Biotransformation — A successful way to deactivate T-2 toxin in growing broiler chickens. Proceedings 15th European Symposium on Poultry Nutrition. Balatonfüred, pp. 618–620.
House, J.D., Nyachoti, C.M. & Abramson, D. (2003): Deoxynivalenol removal from barley intended as swine feed through the use of and abrasive pearling procedure. J. Agric. Fd Chem., 51, 5172–5175.
Abramson D. , 'Deoxynivalenol removal from barley intended as swine feed through the use of and abrasive pearling procedure ' (2003 ) 51 J. Agric. Fd Chem. : 5172 -5175.
Hua, S.S.T., Brandl, M.T., Hernlem, B., Eng, J.G. & Sarreal, S.B.L. (2010): Fluorescent viability stains to probe the metabolic status of aflatoxigenic fungus in dual culture of Aspergillus flavus and Pichia anomala. Mycopathologia, 171, 133–138.
Sarreal S.B.L. , 'Fluorescent viability stains to probe the metabolic status of aflatoxigenic fungus in dual culture of Aspergillus flavus and Pichia anomala ' (2010 ) 171 Mycopathologia : 133 -138.
Jackson, L.S. & Bullerman, L.B. (1999): Effect of processing on Fusarium mycotoxins. Adv. Expl Med. Biol., 459, 243–261.
Bullerman L.B. , 'Effect of processing on Fusarium mycotoxins ' (1999 ) 459 Adv. Expl Med. Biol. : 243 -261.
Jouany, J.-P. (2007): Methods for preventing, decontaminating and minimizing the toxicity of mycotoxins in feeds. Anim. Feed Sci. Technol., 137, 342–362.
Jouany J.-P. , 'Methods for preventing, decontaminating and minimizing the toxicity of mycotoxins in feeds ' (2007 ) 137 Anim. Feed Sci. Technol. : 342 -362.
Kabak, B., Dobson, A.D. & Var, I. (2006): Strategies to prevent mycotoxin contamination of food and animal feed: a review. Crit. Rev. Fd Sci. Nutr., 46, 593–619.
Var I. , 'Strategies to prevent mycotoxin contamination of food and animal feed: a review ' (2006 ) 46 Crit. Rev. Fd Sci. Nutr. : 593 -619.
Kamimura, H. (1989): Removal of mycotoxins in food processing. -in: Natori, S., Hashimoto, K. & Ueno, Y. (Eds): Mycotoxins and phycotoxins. Elsevier, Amsterdam, pp. 234–245.
Kamimura H. , '', in Mycotoxins and phycotoxins , (1989 ) -.
Krifaton, C., Kriszt, B., Szoboszlay, S., Cserháti, M., Szűcs, Á. & Kukolya, J. (2011): Analysis of aflatoxin-B1-degrading microbes by use of combined toxicity-profiling method. Mutat. Res., 726, 1–7.
Kukolya J. , 'Analysis of aflatoxin-B1-degrading microbes by use of combined toxicity-profiling method ' (2011 ) 726 Mutat. Res. : 1 -7.
Lawlor, P.G. & Lynch, P.B. (2005): Mycotoxin management. Afr. Farm. Fd Process., 46, 12–13.
Lynch P.B. , 'Mycotoxin management ' (2005 ) 46 Afr. Farm. Fd Process. : 12 -13.
László, E., Varga, B. & Veisz, O. (2011): Composition of Fusarium species causing natural spike infection in wheat. Acta Agron. Hung., 59, 255–260.
Veisz O. , 'Composition of Fusarium species causing natural spike infection in wheat ' (2011 ) 59 Acta Agron. Hung. : 255 -260.
Magan, N. & Aldred, D. (2007): Post-harvest control strategies: minimizing mycotoxins in the food chain. Int. J. Fd Microbiol., 119, 131–139.
Aldred D. , 'Post-harvest control strategies: minimizing mycotoxins in the food chain ' (2007 ) 119 Int. J. Fd Microbiol. : 131 -139.
Magan, N. & Baxter, E.S. (1996): Effects of elevated CO2 and temperature on the phyllosphere mycoflora of winter wheat flag leaves during ripening. Ann. Appl. Biol., 129, 189–195.
Baxter E.S. , 'Effects of elevated CO2 and temperature on the phyllosphere mycoflora of winter wheat flag leaves during ripening ' (1996 ) 129 Ann. Appl. Biol. : 189 -195.
Magan, N., Medina, A. & Aldred, D. (2011): Possible climate-change effects on mycotoxin contamination of food crops pre- and postharvest. Pl. Pathol., 60, 150–163.
Aldred D. , 'Possible climate-change effects on mycotoxin contamination of food crops pre- and postharvest ' (2011 ) 60 Pl. Pathol. : 150 -163.
Magnusson, J., Ström, K., Roos, S., Sjögren, J. & Schnürer, J. (2003): Broad and complex antifungal activity among environmental isolates of lactic acid bacteria. FEMS Microbiol. Lett., 219, 129–135.
Schnürer J. , 'Broad and complex antifungal activity among environmental isolates of lactic acid bacteria ' (2003 ) 219 FEMS Microbiol. Lett. : 129 -135.
Masimango, N., Remacle, J. & Ramaut, J. (1979): Elimination of aflatoxin B1 by clays from contaminated substances. Ann. Nutr. Aliment., 33, 137–147.
Ramaut J. , 'Elimination of aflatoxin B1 by clays from contaminated substances ' (1979 ) 33 Ann. Nutr. Aliment. : 137 -147.
Mesterházy, Á. (2010): A mikotoxinok táplálékláncból való kiiktatásának lehetőségei, a rezisztencianemesítés, a fajtaelismerés és az agrotechnika területén. (Possibilities of the elimination of mycotoxins in the field of resistance breeding, variety approval and agrotechnique.) -in: Kovács, M. (Ed.): Aktualitások a mikotoxin kutatásban. (Recent progress in mycotoxin research.) Agroinform, Budapest, pp. 119–140.
Mézes, M., Balogh, K. & Tóth, K. (2010): Preventive and therapeutic methods against the toxic effects of mycotoxins. — A review. Acta Vet. Hung., 58, 1–17.
Tóth K. , 'Preventive and therapeutic methods against the toxic effects of mycotoxins. — A review ' (2010 ) 58 Acta Vet. Hung. : 1 -17.
Molnar, O., Schatzmayr, G., Fuchs, E. & Prillinger, H. (2004): Trichosporon mycotoxinovorans sp. nov. A new yeast species useful in biological detoxification of various mycotoxins. Syst. Appl. Microbiol., 27, 661–671.
Prillinger H. , 'Trichosporon mycotoxinovorans sp ' (2004 ) 27 nov. A new yeast species useful in biological detoxification of various mycotoxins. Syst. Appl. Microbiol. : 661 -671.
Nagy, Z., Kölber, M. & Mézes, M. (2009): Adszorbensek a mikotoxin-szennyezett takarmányok kedvezőtlen hatásainak a csökkentésére. (Irodalmi összefoglalás). (Adsorbents for the reduction of undesirable effects of mycotoxin contaminated feeds.) Állattenyésztés és Takarmányozás, 58, 477–488.
Mézes M. , 'Adszorbensek a mikotoxin-szennyezett takarmányok kedvezőtlen hatásainak a csökkentésére ' (2009 ) 58 Állattenyésztés és Takarmányozás : 477 -488.
Pasteiner, S. (1997): Coping with mycotoxin contaminated feedstuffs. Feed Int., 18, 12–16.
Pasteiner S. , 'Coping with mycotoxin contaminated feedstuffs ' (1997 ) 18 Feed Int. : 12 -16.
Paster, N., Bartov, I. & Perelman, A. (1985): Studies of the fungistatic activity of antifungal compounds in mash and pelleted feeds. Poult. Sci., 64, 1673–1677.
Perelman A. , 'Studies of the fungistatic activity of antifungal compounds in mash and pelleted feeds ' (1985 ) 64 Poult. Sci. : 1673 -1677.
Paul, S.K., Halder, G., Mondal, M.K. & Samanta, G. (2007): Effect of organic acid salt on the performance and gut health of broiler chicken. J. Poult. Sci., 44, 389–395.
Samanta G. , 'Effect of organic acid salt on the performance and gut health of broiler chicken ' (2007 ) 44 J. Poult. Sci. : 389 -395.
Raju, M.V.L.N. & Devegowda, G. (2000): Influence of esterified glucomannan on performance and organ morphology, serum biochemistry and haematology in broilers exposed to individual and combined mycotoxicosis (aflatoxin, ochratoxin, and T-2 toxin). Br. Poult. Sci., 41, 640–650.
Devegowda G. , 'Influence of esterified glucomannan on performance and organ morphology, serum biochemistry and haematology in broilers exposed to individual and combined mycotoxicosis (aflatoxin, ochratoxin, and T-2 toxin) ' (2000 ) 41 Br. Poult. Sci. : 640 -650.
Ramos, A.J. & Hernandez, E. (1996): In vitro aflatoxin adsorption by means of a montmorillonite silicate. A study of adsorption isotherms. Anim. Feed Sci. Technol., 62, 263–269.
Hernandez E. , 'In vitro aflatoxin adsorption by means of a montmorillonite silicate. A study of adsorption isotherms ' (1996 ) 62 Anim. Feed Sci. Technol. : 263 -269.
Rankin, M. & Grau, C. (2002): Agronomic considerations for molds and mycotoxins in corn silage. Focus on Forage, 4,(1) 1–4.
Grau C. , 'Agronomic considerations for molds and mycotoxins in corn silage ' (2002 ) 4 Focus on Forage : 1 -4.
Richard, E., Heutte, N., Sage, L., Pottier, D., Bouchart, V., Lebailly, P. & Garon, D. (2007): Toxigenic fungi and mycotoxins in mature corn silage. Fd Chem. Toxicol., 45, 2420–2425.
Garon D. , 'Toxigenic fungi and mycotoxins in mature corn silage ' (2007 ) 45 Fd Chem. Toxicol. : 2420 -2425.
Russell, R., Paterson, M. & Lima, N. (2010): How will climate change affect mycotoxins in food? Fd Res. Internat., 43, 1902–1914.
Lima N. , 'How will climate change affect mycotoxins in food? ' (2010 ) 43 Fd Res. Internat. : 1902 -1914.
Sanchis, V. & Magan, N. (2004): Environmental profiles for growth and mycotoxin production. -in: Magan, N. & Olsen, M. (Eds): Mycotoxins in food: Detection and control. Woodhead, Cambridge, pp. 174–189.
Magan N. , '', in Mycotoxins in food: Detection and control , (2004 ) -.
Scudamore, K.A., Guy, R.C.E., Kelleher, B. & MacDonald, S.J. (2008): Fate of the Fusarium mycotoxins, deoxynivalenol, nivalenol and zearalenone, during extrusion of wholemeal wheat grain. Fd Addit. Contam., 25, 331–337.
MacDonald S.J. , 'Fate of the Fusarium mycotoxins, deoxynivalenol, nivalenol and zearalenone, during extrusion of wholemeal wheat grain ' (2008 ) 25 Fd Addit. Contam. : 331 -337.
Skládanka, J., Nedelnik, J., Adam, V., Golezal, P., Moravcová, H. & Dohnal, V. (2011): Forage as a primary source of mycotoxins in animal diets. Int. J. Environ. Res. Publ. Health, 8, 37–50.
Dohnal V. , 'Forage as a primary source of mycotoxins in animal diets ' (2011 ) 8 Int. J. Environ. Res. Publ. Health : 37 -50.
Sobrova, P., Adam, V., Vasatkova, A., Beklova, M., Zeman, L. & Vizek, K. (2010): Deoxynivalenol and its toxicity. Interdiscipl. Toxicol., 3, 101–106.
Vizek K. , 'Deoxynivalenol and its toxicity ' (2010 ) 3 Interdiscipl. Toxicol. : 101 -106.
Yiannikuris, A. & Jouany, J.-P. (2002): Mycotoxins in feeds and their fate in animals: a review. Anim. Res., 51, 81–99.
Jouany J.-P. , 'Mycotoxins in feeds and their fate in animals: a review ' (2002 ) 51 Anim. Res. : 81 -99.
Varga, J., Tóth, B. & Téren, J. (2005): Mycotoxin producing fungi and mycotoxins in foods in Hungary in the period 1994–2002. Acta Alimentaria, 34, 267–275.
Téren J. , 'Mycotoxin producing fungi and mycotoxins in foods in Hungary in the period 1994–2002 ' (2005 ) 34 Acta Alimentaria : 267 -275.
Van Rensburg, J.C., Van Rensburg, C.E.J., Van Ryssen, J.B.J., Casey, N.H. & Rottinghaus, G.E. (2006): In vitro and in vivo assessment of humic acid as an aflatoxin binder in broiler chickens. Biomin World Nutrition Forum. Vienna (Abstr. 12).
Von Boberfeld, W.O. & Banzhaf, K. (2006): Yield and forage quality of different ×Festulolium cultivars in winter. J. Agron. Crop Sci., 192, 239–247.
Banzhaf K. , 'Yield and forage quality of different ×Festulolium cultivars in winter ' (2006 ) 192 J. Agron. Crop Sci. : 239 -247.