Ganoderma is a worldwide distributed genus of polyporoid fungi causing white-rot. The sporocarps of these species are popular drug in the traditional medicine of the Far East. Although several species are proven to contain chemicals of different biological activities, only Ganoderma lucidum is cultivated on the large scale. It is an important goal of mushroom growing to involve genetically diverse strains in this field of industry (e.g. for Agaricus, Pleurotus), thus the range of cultivated Ganoderma species should also be broadened in the future. Within the Carpathian Basin, we have the possibility to isolate strains from 6 species beside G. lucidum: G. adspersum, G. applanatum (syn. G. lipsiense), G. carnosum (syn. G. atkinsonii), G. cupreolaccatum (G. pfeifferi), G. resinaceum and G. valesiacum. In the present review, by describing the taxonomical status and the ecological characteristic of the species, we depict the biological background of the medicinal potential, as well as the cultivation possibilities (both sporocarp production and liquid mycelia cultures) of these species.