Authors:
E.E. Sage Department of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor. Malaysia

Search for other papers by E.E. Sage in
Current site
Google Scholar
PubMed
Close
,
Y.X. Chang ProgramAsasiPintar, Pusat Permata Pintar Negara, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor. Malaysia

Search for other papers by Y.X. Chang in
Current site
Google Scholar
PubMed
Close
,
R. Wickneswari Department of Earth Sciences and Environment, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor. Malaysia

Search for other papers by R. Wickneswari in
Current site
Google Scholar
PubMed
Close
, and
M.M. Mackeen Department of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor. Malaysia
Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor. Malaysia

Search for other papers by M.M. Mackeen in
Current site
Google Scholar
PubMed
Close
Restricted access

The neurotransmitter γ-aminobutyric acid (GABA) is a functional food ingredient of growing importance in the preparation of GABA-enriched germinated brown rice (GBR). Quantification of GABA levels during germination in a locally developed high yielding red rice variety (UKMRC-9) was carried out via high-performance liquid chromatography (HPLC) analysis using pre-column chemical derivatisation with 2-hydroxynaphthaldehyde (HN) using a UV detection system. Factors that influence rice germination such as soaking time and temperature were also studied. The results of this study showed that the UKMRC-9 rice variety soaked in water for 6 hours at 35 °C yielded the highest value for both germination percentage (95.4±1.2%) and GABA content (411 μg g-1). This suggests that long soaking times of 1-4 days can be substituted by short soaking times to produce high GABA levels in germinated brown rice.

  • Bhuiyan, M., Narimah, M., Rahim, H.A., Abdullah, M. & Wickneswari, R. (2011): Transgressive variants for red pericarp grain with high yield potential derived from Oryza rufi pogon x Oryza sativa: Field evaluation, screening for blast disease, QTL validation and background marker analysis for agronomic traits. Field Crop Res.,121, 232-239.

    • Search Google Scholar
    • Export Citation
  • Bown, A.W., MacGregor, K.B. & Shelp, B.J. (2006): Gamma-aminobutyrate: Defense against invertebrate pests? Trends Plant Sci., 11, 424-427.

    • Search Google Scholar
    • Export Citation
  • Boy, F., Evans, C.J., Edden, R.A., Singh, K.D., Husain, M. & Sumner, P. (2010): Individual differences in subconscious motor control predicted by GABA concentration in SMA. Curr. Biol., 20, 1779-1785.

    • Search Google Scholar
    • Export Citation
  • Carroll, A.D., Fox, G.G., Laurie, S., Phillips, R., Ratcliffe, R.G. & Stewart, G.R. (1994): Ammonium assimilation and the role of [gamma]-aminobutyric acid in pH homeostasis in carrot cell suspensions. Plant Physiol., 106, 513-520.

    • Search Google Scholar
    • Export Citation
  • Del Rio, R.M. & Caballero, A.L. (1980): Presence of γ-aminobutyric acid in rat ovary. J. Neurochem., 34, 1584-1586.

  • Ding, J., Yang, T., Feng, H., Dong, M., Slavin, M. & Zhao, S. (2016): Enhancing contents of γ-aminobutyric acid (GABA) and other micronutrients in dehulled rice during germination under normoxic and hypoxic conditions. J. Agr. Food Chem., 64(5),1094-1102.

    • Search Google Scholar
    • Export Citation
  • Fasahat, P., Abdullah, A., Muhammad, K., Karupaiah, T.& Ratnam, W. (2012): Red pericarp advanced breeding lines derived from Oryza rufi pogon x Oryza sativa: Physicochemical properties, total antioxidant activity, phenolic compounds and vitamin E content. Adv. J. Food Sci. Technol., 4, 155-165.

    • Search Google Scholar
    • Export Citation
  • Franciosi, E., Carafa, I., Nardin, T., Schiavon, S., Poznanski, E. & Tuohy, K.M. (2015): Biodiversity and γ-aminobutyric acid production by lactic acid bacteria isolated from traditional alpine raw cow's milk cheeses. Biomed Res. Int., 2015, 625740.

    • Search Google Scholar
    • Export Citation
  • ICH Guideline (2005): Validation of analytical procedures: Text and methodology Q2 (R1). -in: I nternational Conference On Harmonization, Geneva, Switzerland, pp. 11-12.

    • Search Google Scholar
    • Export Citation
  • Hayat, A., Jahangir, T.M., Khuhawar, M.Y., Alamgir, M., Siddiqui, A.J. & Musharraf, S.G. (2014): Simultaneous HPLC determination of gamma-aminobutyric acid (GABA) and lysine in selected Pakistani rice varieties by pre-column derivatization with 2-hydroxynaphthaldehyde. J. Cereal Sci., 60(2), 356-360.

    • Search Google Scholar
    • Export Citation
  • Kanai, T., Atomi, H., Umemura, K., Ueno, H., Teranishi, Y.& Tanaka, A. (1996): A novel heterologous gene expression system in Saccharomyces cerevisiae using the isocitrate lyase gene promoter from Candida tropicalis. Appl. Microbiol. Biot., 44, 759-765.

    • Search Google Scholar
    • Export Citation
  • Khuhawar, M.Y. & Rajper, A.D. (2003): Liquid chromatographic determination of gamma-aminobutyric acid in cerebrospinal fluid using 2-hydroxynaphthaldehyde as derivatizing reagent. J. Chromatogr. B, 788, 413-418.

    • Search Google Scholar
    • Export Citation
  • Komatsuzaki, N., Tsukahara, K., Toyoshima, H., Suzuki, T., Shimizu, N. & Kimura, T. (2007): Effect of soaking and gaseous treatment on GABA content in germinated brown rice. J. Food Eng., 78, 556-560.

    • Search Google Scholar
    • Export Citation
  • Obata, K. (2013): Synaptic inhibition and γ-aminobutyric acid in the mammalian central nervous system. 89, 139-156.

  • Patterson, E., Rya.n, P.M., Wiley, N., Carafa, I., Sherwin, E. & Ross, R.P (2019): Gamma-aminobutyric acid producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome. Sci. Rep., 9(1), 1-15.

    • Search Google Scholar
    • Export Citation
  • Plokhov, A.Y., Gusyatiner, M., Yampolskayv, T., Kaluzhsky, V., Sukhareva, B. & Schulga, A. (2000): Preparation of γ-aminobutyric acid using E. coli cells with high activity of glutamate decarboxylase. Appl Biochem. Biotech., 88, 257-265.

    • Search Google Scholar
    • Export Citation
  • Roberts, E. & Frankel, S. (1950): γ-Aminobutyric acid in brain: its formation from glutamic acid. J. Biol. Chem., 187, 55-63.

  • Roohinejad, S., Mirhosseini, H., Saari, N., Mustafa, S., Alias, I. & Manap, M.Y. (2009): Evaluation of GABA, crude protein and amino acid composition from different varieties of Malaysian's brown rice. Aust. J. Crop Sci., 3, 184.

    • Search Google Scholar
    • Export Citation
  • Roohinejad, S., Omidizadeh, A., Mirhosseini, H., Saari, N., Mustafa, S. & Abd Manap, M.Y. (2011): Effect of pre-germination time on amino acid profile and gamma aminobutyric acid (GABA) contents in different varieties of Malaysian brown rice. Int. J. Food Prop., 14, 1386-1399.

    • Search Google Scholar
    • Export Citation
  • Sabu, K.K., Abdullah, M.Z., Lim, L.S. & Ratnam, W. (2006): Development and evaluation of advanced backcross families of rice for agronomically important traits. Commun. Biometry Crop Sci., 1, 111-123.

    • Search Google Scholar
    • Export Citation
  • Saikusa, T., Horino, T. & Mori, Y. (1994): Accumulation of γ-aminobutyric acid (GABA) in the rice germ during water soaking. Biosci. Biotech. Bioch., 58, 2291-2292.

    • Search Google Scholar
    • Export Citation
  • Se, C.H., Chuah, K.-A., Mishra, A., Ratnam, W. & Karupaiah, T. (2016): Evaluating crossbred red rice variants for postprandial glucometabolic responses: A comparison with commercial varieties. Nutrients, 8, 308. (16 pages).

    • Search Google Scholar
    • Export Citation
  • Se, C.H., Khor, B.H. & Karupaiah, T. (2015): Prospects in development of quality rice for human nutrition. Malays. Appl. Biol., 44, 1-31.

    • Search Google Scholar
    • Export Citation
  • Snedden, W.A., Arazi, T., Fromm, H. & Shelp, B.J. (1995): Calcium/calmodulin activation of soybean glutamate decarboxylase. Plant Physiol., 108, 543-549.

    • Search Google Scholar
    • Export Citation
  • Stagg, C.J., Bachtiar, V. & Johansen-Berg, H. (2011): The role of GABA in human motor learning. Curr. Biol., 21, 480-484.

  • Woodrow, P., Ciarmiello, L.F., Annunziata, M.G., Pacifico, S., Iannuzzi, F. & Carillo, P (2017): Durum wheat seedling responses to simultaneous high light and salinity involve a fine reconfiguration of amino acids and carbohydrate metabolism. Physiol. Plant., 159, 290-312.

    • Search Google Scholar
    • Export Citation
  • Zhao, M., Lin, Y. & Chen, H. (2020): Improving nutritional quality of rice for human health. Theor. Appl Genet., 8, 1-17.

  • Collapse
  • Expand

Senior editors

Editor(s)-in-Chief: András Salgó, Budapest University of Technology and Economics, Budapest, Hungary

Co-ordinating Editor(s) Marianna Tóth-Markus, Budapest, Hungary

Co-editor(s): A. Halász, Budapest, Hungary

       Editorial Board

  • László Abrankó, Hungarian University of Agriculture and Life Sciences, Budapest, Hungary
  • Tamás Antal, University of Nyíregyháza, Nyíregyháza, Hungary
  • Diána Bánáti, University of Szeged, Szeged, Hungary
  • József Baranyi, Institute of Food Research, Norwich, UK
  • Ildikó Bata-Vidács, Eszterházy Károly Catholic University, Eger, Hungary
  • Ferenc Békés, FBFD PTY LTD, Sydney, NSW Australia
  • György Biró, Budapest, Hungary
  • Anna Blázovics, Semmelweis University, Budapest, Hungary
  • Francesco Capozzi, University of Bologna, Bologna, Italy
  • Marina Carcea, Research Centre for Food and Nutrition, Council for Agricultural Research and Economics Rome, Italy
  • Zsuzsanna Cserhalmi, Budapest, Hungary
  • Marco Dalla Rosa, University of Bologna, Bologna, Italy
  • István Dalmadi, Hungarian University of Agriculture and Life Sciences, Budapest, Hungary
  • Katarina Demnerova, University of Chemistry and Technology, Prague, Czech Republic
  • Mária Dobozi King, Texas A&M University, Texas, USA
  • Muying Du, Southwest University in Chongqing, Chongqing, China
  • Sedef Nehir El, Ege University, Izmir, Turkey
  • Søren Balling Engelsen, University of Copenhagen, Copenhagen, Denmark
  • Éva Gelencsér, Budapest, Hungary
  • Vicente Manuel Gómez-López, Universidad Católica San Antonio de Murcia, Murcia, Spain
  • Jovica Hardi, University of Osijek, Osijek, Croatia
  • Hongju He, Henan Institute of Science and Technology, Xinxiang, China
  • Károly Héberger, Research Centre for Natural Sciences, ELKH, Budapest, Hungary
  • Nebojsa Ilić, University of Novi Sad, Novi Sad, Serbia
  • Dietrich Knorr, Technische Universität Berlin, Berlin, Germany
  • Hamit Köksel, Hacettepe University, Ankara, Turkey
  • Katia Liburdi, Tuscia University, Viterbo, Italy
  • Meinolf Lindhauer, Max Rubner Institute, Detmold, Germany
  • Min-Tze Liong, Universiti Sains Malaysia, Penang, Malaysia
  • Marena Manley, Stellenbosch University, Stellenbosch, South Africa
  • Miklós Mézes, Hungarian University of Agriculture and Life Sciences, Gödöllő, Hungary
  • Áron Németh, Budapest University of Technology and Economics, Budapest, Hungary
  • Perry Ng, Michigan State University,  Michigan, USA
  • Quang Duc Nguyen, Hungarian University of Agriculture and Life Sciences, Budapest, Hungary
  • Laura Nyström, ETH Zürich, Switzerland
  • Lola Perez, University of Cordoba, Cordoba, Spain
  • Vieno Piironen, University of Helsinki, Finland
  • Alessandra Pino, University of Catania, Catania, Italy
  • Mojmir Rychtera, University of Chemistry and Technology, Prague, Czech Republic
  • Katharina Scherf, Technical University, Munich, Germany
  • Regine Schönlechner, University of Natural Resources and Life Sciences, Vienna, Austria
  • Arun Kumar Sharma, Department of Atomic Energy, Delhi, India
  • András Szarka, Budapest University of Technology and Economics, Budapest, Hungary
  • Mária Szeitzné Szabó, Budapest, Hungary
  • Sándor Tömösközi, Budapest University of Technology and Economics, Budapest, Hungary
  • László Varga, Széchenyi István University, Mosonmagyaróvár, Hungary
  • Rimantas Venskutonis, Kaunas University of Technology, Kaunas, Lithuania
  • Barbara Wróblewska, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences Olsztyn, Poland

 

Acta Alimentaria
E-mail: Acta.Alimentaria@uni-mate.hu

Indexing and Abstracting Services:

  • Biological Abstracts
  • BIOSIS Previews
  • CAB Abstracts
  • CABELLS Journalytics
  • Chemical Abstracts
  • Current Contents: Agriculture, Biology and Environmental Sciences
  • Elsevier Science Navigator
  • Essential Science Indicators
  • Global Health
  • Index Veterinarius
  • Science Citation Index
  • Science Citation Index Expanded (SciSearch)
  • SCOPUS
  • The ISI Alerting Services

2023  
Web of Science  
Journal Impact Factor 0,8
Rank by Impact Factor Q4 (Food Science & Technology)
Journal Citation Indicator 0.19
Scopus  
CiteScore 1.8
CiteScore rank Q3 (Food Science)
SNIP 0.323
Scimago  
SJR index 0.235
SJR Q rank Q3

Acta Alimentaria
Publication Model Hybrid
Submission Fee none
Article Processing Charge 450 EUR/article (only for OA publications)
Printed Color Illustrations 40 EUR (or 10 000 HUF) + VAT / piece
Regional discounts on country of the funding agency World Bank Lower-middle-income economies: 50%
World Bank Low-income economies: 100%
Further Discounts Editorial Board / Advisory Board members: 50%
Corresponding authors, affiliated to an EISZ member institution subscribing to the journal package of Akadémiai Kiadó: 100%
Subscription fee 2025 Online subsscription: 880 EUR / 968 USD
Print + online subscription: 1016 EUR / 1116 USD
Subscription Information Online subscribers are entitled access to all back issues published by Akadémiai Kiadó for each title for the duration of the subscription, as well as Online First content for the subscribed content.
Purchase per Title Individual articles are sold on the displayed price.

Acta Alimentaria
Language English
Size B5
Year of
Foundation
1972
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia    
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0139-3006 (Print)
ISSN 1588-2535 (Online)

 

Monthly Content Usage

Abstract Views Full Text Views PDF Downloads
Oct 2024 270 0 0
Nov 2024 92 0 0
Dec 2024 58 0 0
Jan 2025 129 0 0
Feb 2025 143 0 0
Mar 2025 115 0 0
Apr 2025 0 0 0