Authors:
C. Bal Oguzeli Vocational School, University of Gaziantep, Gaziantep, Türkiye

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M. Sevindik Department of Biology, Faculty of Engineering and Natural Sciences, University of Osmaniye Korkut Ata, Osmaniye, 80000, Türkiye

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T. Krupodorova Department of Plant Food Products and Biofortification, Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine, Kyiv, 04123, Ukraine

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E.C. Eraslan Department of Biology, Faculty of Engineering and Natural Sciences, University of Osmaniye Korkut Ata, Osmaniye, 80000, Türkiye

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Abstract

Mushrooms gained significant attention in the field of health due to their rich biochemical composition and strong antioxidant potential. In this study, the biological activities of Macrolepiota mastoidea mushroom were investigated. The total carbohydrate and protein contents of the mushroom and its antioxidant, enzyme inhibition, and antiproliferative properties were evaluated. According to the obtained data, the total carbohydrate and total protein contents of M. mastoidea were determined as an important indicator for the biological activities of the mushroom. In addition, the high levels of phenolic and flavonoid compounds revealed that the mushroom exhibited strong antioxidant activity. The results obtained in tests such as DPPH and FRAP show that M. mastoidea has a high capacity to neutralise free radicals. In enzyme inhibition tests, significant effects were observed on acetylcholinesterase, butyrylcholinesterase, amylase, and glucosidase, suggesting that the mushroom may provide potential benefits in the treatment of neurological diseases and diabetes. In addition, it was determined that the antiproliferative effect against A549 lung cancer cell line was dose-dependent. These findings indicate that M. mastoidea is a valuable biological resource that can be used in health areas such as antioxidant defense, enzyme modulation, and cancer treatment. Advanced molecular and cellular studies are recommended to better understand the mechanisms of this effect.

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  • Akata, I., Zengin, G., Picot, C.M.N., and Mahomoodally, M.F. (2019). Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family. South African Journal of Botany, 120: 9599.

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  • Gürgen, A. and Sevindik, M. (2025). Single and multi-objective optimization of the red pine mushroom Lactarius deliciosus (Agaricomycetes) extraction conditions using artificial ıntelligence methods and biological activities of optimized extracts. International Journal of Medicinal Mushrooms, 27(2): 5973.

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  • Gürgen, A., Unal, O., and Sevindik, M. (2024). Biological activities of the golden chantarelle mushroom Cantharellus cibarius (Agaricomycetes) extracts obtained as a result of single and multi-objective optimization studies. International Journal of Medicinal Mushrooms, 26(12): 6374.

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  • Im, K.H., Nguyen, T.K., Kim, J.K., Choi, J., and Lee, T.S. (2016). Evaluation of anticholinesterase and inflammation inhibitory activity of medicinal mushroom Phellinus pini (Basidiomycetes) fruiting bodies. International Journal of Medicinal Mushrooms, 18(11): 10111022.

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  • Korkmaz, A.I., Akgul, H., Sevindik, M., and Selamoglu, Z. (2018). Study on determination of bioactive potentials of certain lichens. Acta Alimentaria, 47(1): 8087.

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  • Krüzselyi, D., Kovács, D., and Vetter, J. (2016). Chemical analysis of king oyster mushroom (Pleurotus eryngii) fruitbodies. Acta Alimentaria, 45(1): 2027.

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  • Mohammed, F.S., Sevindik, M., and Uysal, I. (2023). Total phenolic, flavonoid, protein contents and biological activities of wild mustard. Acta Alimentaria, 52(3): 449457.

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  • Savran, A., Zengin, G., Aktumsek, A., Mocan, A., Glamoćlija, J., Ćirić, A., and Soković, M. (2016). Phenolic compounds and biological effects of edible Rumex scutatus and Pseudosempervivum sempervivum: potential sources of natural agents with health benefits. Food & Function, 7(7): 32523262.

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  • Sevindik, M. (2019). The novel biological tests on various extracts of Cerioporus varius. Fresenius Environmental Bulletin, 28(5): 37133717.

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  • Sevindik, M., Akgul, H., Akata, I., Alli, H., and Selamoglu, Z. (2017). Fomitopsis pinicola in healthful dietary approach and their therapeutic potentials. Acta Alimentaria, 46(4): 464469.

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  • Sevindik, M., Gürgen, A., Khassanov, V.T., and Bal, C. (2024). Biological activities of ethanol extracts of Hericium erinaceus obtained as a result of optimization analysis. Foods, 13(10): 1560.

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  • Stajić, M., Vukojević, J., and Ćilerdžić, J. (2019). Mushrooms as potential natural cytostatics. In: Agrawal, D.C. and Dhanasekaran, M. (Eds.), Medicinal mushrooms: recent progress in research and development. Springer International Publishing, Switzerland, pp. 143168.

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  • Vetter, J. (2019). Biological values of cultivated mushrooms – a review. Acta Alimentaria, 48(2): 229240.

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Senior editors

Editor(s)-in-Chief: András Salgó, Budapest University of Technology and Economics, Budapest, Hungary

Co-ordinating Editor(s) Marianna Tóth-Markus, Budapest, Hungary

Co-editor(s): A. Halász, Budapest, Hungary

       Editorial Board

  • László Abrankó, Hungarian University of Agriculture and Life Sciences, Budapest, Hungary
  • Tamás Antal, University of Nyíregyháza, Nyíregyháza, Hungary
  • Diána Bánáti, University of Szeged, Szeged, Hungary
  • József Baranyi, Institute of Food Research, Norwich, UK
  • Ildikó Bata-Vidács, Eszterházy Károly Catholic University, Eger, Hungary
  • Ferenc Békés, FBFD PTY LTD, Sydney, NSW Australia
  • György Biró, Budapest, Hungary
  • Anna Blázovics, Semmelweis University, Budapest, Hungary
  • Francesco Capozzi, University of Bologna, Bologna, Italy
  • Marina Carcea, Research Centre for Food and Nutrition, Council for Agricultural Research and Economics Rome, Italy
  • Zsuzsanna Cserhalmi, Budapest, Hungary
  • Marco Dalla Rosa, University of Bologna, Bologna, Italy
  • István Dalmadi, Hungarian University of Agriculture and Life Sciences, Budapest, Hungary
  • Katarina Demnerova, University of Chemistry and Technology, Prague, Czech Republic
  • Mária Dobozi King, Texas A&M University, Texas, USA
  • Muying Du, Southwest University in Chongqing, Chongqing, China
  • Sedef Nehir El, Ege University, Izmir, Turkey
  • Søren Balling Engelsen, University of Copenhagen, Copenhagen, Denmark
  • Éva Gelencsér, Budapest, Hungary
  • Vicente Manuel Gómez-López, Universidad Católica San Antonio de Murcia, Murcia, Spain
  • Jovica Hardi, University of Osijek, Osijek, Croatia
  • Hongju He, Henan Institute of Science and Technology, Xinxiang, China
  • Károly Héberger, Research Centre for Natural Sciences, ELKH, Budapest, Hungary
  • Nebojsa Ilić, University of Novi Sad, Novi Sad, Serbia
  • Dietrich Knorr, Technische Universität Berlin, Berlin, Germany
  • Hamit Köksel, Hacettepe University, Ankara, Turkey
  • Katia Liburdi, Tuscia University, Viterbo, Italy
  • Meinolf Lindhauer, Max Rubner Institute, Detmold, Germany
  • Min-Tze Liong, Universiti Sains Malaysia, Penang, Malaysia
  • Marena Manley, Stellenbosch University, Stellenbosch, South Africa
  • Miklós Mézes, Hungarian University of Agriculture and Life Sciences, Gödöllő, Hungary
  • Áron Németh, Budapest University of Technology and Economics, Budapest, Hungary
  • Perry Ng, Michigan State University,  Michigan, USA
  • Quang Duc Nguyen, Hungarian University of Agriculture and Life Sciences, Budapest, Hungary
  • Laura Nyström, ETH Zürich, Switzerland
  • Lola Perez, University of Cordoba, Cordoba, Spain
  • Vieno Piironen, University of Helsinki, Finland
  • Alessandra Pino, University of Catania, Catania, Italy
  • Mojmir Rychtera, University of Chemistry and Technology, Prague, Czech Republic
  • Katharina Scherf, Technical University, Munich, Germany
  • Regine Schönlechner, University of Natural Resources and Life Sciences, Vienna, Austria
  • Arun Kumar Sharma, Department of Atomic Energy, Delhi, India
  • András Szarka, Budapest University of Technology and Economics, Budapest, Hungary
  • Mária Szeitzné Szabó, Budapest, Hungary
  • Sándor Tömösközi, Budapest University of Technology and Economics, Budapest, Hungary
  • László Varga, Széchenyi István University, Mosonmagyaróvár, Hungary
  • Rimantas Venskutonis, Kaunas University of Technology, Kaunas, Lithuania
  • Barbara Wróblewska, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences Olsztyn, Poland

 

Acta Alimentaria
E-mail: Acta.Alimentaria@uni-mate.hu

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Acta Alimentaria
Language English
Size B5
Year of
Foundation
1972
Volumes
per Year
1
Issues
per Year
4
Founder Magyar Tudományos Akadémia    
Founder's
Address
H-1051 Budapest, Hungary, Széchenyi István tér 9.
Publisher Akadémiai Kiadó
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
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Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0139-3006 (Print)
ISSN 1588-2535 (Online)

 

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