Cereal Research Communications
Volume/Issue:
Volume 36: Issue Supplement-6
The wheat response to deoxynivalenol: Does maintenance of hormone homeostasis and alleviation of oxidative stress play an important role in toxin tolerance?
Authors: Fiona Doohan 1 , Chan Arunachalam 1 , Shumei Jiang 1 , Mojibur Khan 1 , Damian Egan 1 , Guillaume Erard 1 , and Stephanie Walter 1
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  • 1 University College Dublin Molecular Plant-Microbe Interactions Group, School of Biology and Environmental Science, College of Life Sciences Belfield, Dublin 4 Ireland
DOI:
https://doi.org/10.1556/crc.36.2008.suppl.b.20
Page Count:
233–237
Publication Date:
01 Sep 2008
Online Publication Date:
12 Sep 2008
Article Category:
Research Article
Restricted access

The Fusarium mycotoxin deoxynivalenol (DON) is a potent inhibitor of eukaryotic protein synthesis and acts as a virulence factor during infection of wheat heads. Some wheat genotypes can tolerate DON and resist its deleterious effects; others cannot. Transcriptome studies identified several genes up-regulated in spikelets of the DON-resistant wheat cultivar CM82036 in response to DON treatment. We will discuss how the finding presented herein and other recent findings contribute to the hypothesis that management of hormone homeostasis and alleviation of oxidative stress in DON-challenged wheat might facilitate cell survival and thereby retard fungal colonisation.

  • Ahlfors, R., Lång, S., Overmyer, K., Jaspers, P., Brosché, M., Tauriainen, A., Kollist, H., Tuominen, H., Belles-Boix, E., Piippo, M., Inzé, D., Palva, E.T., Kangasjärvi, J. 2004. Arabidopsis RADICAL-INDUCED CELL DEATH1 belongs to the WWE protein-protein interaction domain protein family and modulates abscisic acid, ethylene, and methyl jasmonate responses. Plant Cell 16 : 1925–1937.

    Kangasjärvi J. , 'Arabidopsis RADICAL-INDUCED CELL DEATH1 belongs to the WWE protein-protein interaction domain protein family and modulates abscisic acid, ethylene, and methyl jasmonate responses ' (2004 ) 16 Plant Cell : 1925 -1937.

    • Search Google Scholar

  • Amor, Y., Chevion, M., Levine, A. 2000. Anoxia pretreatment protects soybean cells against H 2 O 2 -induced cell death: possible involvement of peroxidases and of alternative oxidase. FEBS Lett. 477 :175–180.

    Levine A. , 'Anoxia pretreatment protects soybean cells against H2O2-induced cell death: possible involvement of peroxidases and of alternative oxidase ' (2000 ) 477 FEBS Lett. : 175 -180.

    • Search Google Scholar

  • Ansari, K.I., Walter, S., Brennan, J.M., Lemmens, M., Kessans, S., McGahern, A., Egan, D., Doohan, F.M. 2007. Retrotransposon and gene activation in wheat in response to mycotoxigenic and nonmycotoxigenic-associated Fusarium stress. Theor. Appl. Genet. 114 : 927–937.

    Doohan F.M. , 'Retrotransposon and gene activation in wheat in response to mycotoxigenic and nonmycotoxigenic-associated Fusarium stress ' (2007 ) 114 Theor. Appl. Genet. : 927 -937.

    • Search Google Scholar

  • Bai, G.H., Desjardins, A.E., Plattner, R.D. 2002. Deoxynivalenol-nonproducing Fusarium graminearum causes initial infection, but does not cause disease spread in wheat spikes. Mycopathol. 153 : 91–98.

    Plattner R.D. , 'Deoxynivalenol-nonproducing Fusarium graminearum causes initial infection, but does not cause disease spread in wheat spikes ' (2002 ) 153 Mycopathol. : 91 -98.

    • Search Google Scholar

  • Boddu, J., Cho, S., Muehlbauer, G.J. 2007. Transcriptome Analysis of Trichothecene-Induced Gene Expression in Barley. Mol. Plant Microbe Interact. 20 : 1364–1375.

    Muehlbauer G.J. , 'Transcriptome Analysis of Trichothecene-Induced Gene Expression in Barley ' (2007 ) 20 Mol. Plant Microbe Interact. : 1364 -1375.

    • Search Google Scholar

  • Buerstmayr, H., Steiner, B., Hartl, L., Griesser, M., Angerer, N., Lengauer, D., Miedaner, T., Schneider, B., Lemmens, M. 2003. Molecular mapping of QTLs for Fusarium head blight resistance in spring wheat. II. Resistance to fungal penetration and spread. Theor. Appl. Genet. 107 : 503–508.

    Lemmens M. , 'Molecular mapping of QTLs for Fusarium head blight resistance in spring wheat. II. Resistance to fungal penetration and spread ' (2003 ) 107 Theor. Appl. Genet. : 503 -508.

    • Search Google Scholar

  • Bushnell, W.R., Seeland, T.M. 2006. Effects of DON on barley leaf tissues, summary of results. The Effects of Deoxynivalenol on Barley Leaf Tissue. In: SM Canty, A Clark, D Van Sanford, eds, Proceedings of the National Fusarium Head Blight Forum; 2006 Dec 10–12;Research Triangle Park, North Carolina, USA. pp. 35–36.

  • Bushnell, W.R., Seeland, T.M., Perkins-Veazie, P., Krueger, D.E., Collins, J., Russo, V.M. 2004. The Effects of Deoxynivalenol on Barley Leaf Tissue. In: Tsuyumu S, Leach JE, Shiraishi T and Wolpert T (Editors): Genomic and Genetic Analysis of Plant Parasitism and Defense. APS Press, The American Phytopathological Society, St. Paul, Minnesota: pp. 270–281.

    Russo V.M. , '', in Genomic and Genetic Analysis of Plant Parasitism and Defense , (2004 ) -.

  • Chen, S., Vaghchhipawala, Z., Li, W., Asard, H., Dickman, M.B. 2004. Tomato phospholipid hydroperoxide glutathione peroxidase inhibits cell death induced by Bax and oxidative stresses in yeast and plants. Plant Physiol. 135 : 1630–1641.

    Dickman M.B. , 'Tomato phospholipid hydroperoxide glutathione peroxidase inhibits cell death induced by Bax and oxidative stresses in yeast and plants ' (2004 ) 135 Plant Physiol. : 1630 -1641.

    • Search Google Scholar

  • Desmond, O.J., Manners, J.M., Stephens, A.E., MacLean, D.J., Schenk, P.M., Gardiner, D.M., Munn, A.L., Kazan, K. 2008. The Fusarium mycotoxin deoxynivalenol elicits hydrogen peroxide production, programmed cell death and defence responses in wheat. Mol. Plant Pathol. 9 : 435–445.

    Kazan K. , 'The Fusarium mycotoxin deoxynivalenol elicits hydrogen peroxide production, programmed cell death and defence responses in wheat ' (2008 ) 9 Mol. Plant Pathol. : 435 -445.

    • Search Google Scholar

  • Jones, D.P. 2006. Disruption of mitochondrial redox circuitry in oxidative stress. Chem Biol. Interact. 163 :38–53.

    Jones D.P. , 'Disruption of mitochondrial redox circuitry in oxidative stress ' (2006 ) 163 Chem Biol. Interact. : 38 -53.

    • Search Google Scholar

  • Kampranis, S.C., Damianova, R., Atallah, M., Toby, G., Kondi, G., Tsichlis, P.N., Makris, A.M. 2000. A novel plant glutathione S-transferase/peroxidase suppresses Bax lethality in yeast. J. Biol. Chem. 275 :29207–29216.

    Makris A.M. , 'A novel plant glutathione S-transferase/peroxidase suppresses Bax lethality in yeast ' (2000 ) 275 J. Biol. Chem. : 29207 -29216.

    • Search Google Scholar

  • Katiyar-Agarwal, S., Zhu, J., Kim, K., Agarwal, M., Fu, X., Huang, A., Zhu, J.-K. 2006. The plasma membrane Na + /H + antiporter SOS1 interacts with RCD1 and functions in oxidative stress tolerance in Arabidopsis . Proc. Natl. Acad. Sci. USA 103 : 18816–18821.

    Zhu J.-K. , 'The plasma membrane Na+/H+ antiporter SOS1 interacts with RCD1 and functions in oxidative stress tolerance in Arabidopsis ' (2006 ) 103 Proc. Natl. Acad. Sci. USA : 18816 -18821.

    • Search Google Scholar

  • Kilili, K.G., Atanassova, N., Vardanyan, A., Clatot, N., Al-Sabarna, K., Kanellopoulos, P.N., Makris, A.M., Kampranis, S.C. 2004. Differential Roles of Tau Class Glutathione S -Transferases in Oxidative Stress. J. Biol. Chem. 279 : 24540–24551.

    Kampranis S.C. , 'Differential Roles of Tau Class Glutathione S-Transferases in Oxidative Stress ' (2004 ) 279 J. Biol. Chem. : 24540 -24551.

    • Search Google Scholar

  • Lemmens, M., Scholz, U., Berthiller, F., Dall’Asta, C., Koutnik, A., Schuhmacher, R., Adam, G., Buerstmayr, H., Mesterházy, Á., Krska, R., Ruckenbauer, P. 2005. The ability to detoxify the mycotoxin deoxynivalenol co-localizes with a major QTL for Fusarium head blight resistance in wheat. Mol. Plant-Microbe Interact. 18 : 1318–1324.

    Ruckenbauer P. , 'The ability to detoxify the mycotoxin deoxynivalenol co-localizes with a major QTL for Fusarium head blight resistance in wheat ' (2005 ) 18 Mol. Plant-Microbe Interact. : 1318 -1324.

    • Search Google Scholar

  • Masuda, D., Ishida, M., Yamaguchi, K., Yamaguchi, I., Kimura, M., Nishiuchi, T. 2007. Phytotoxic effects of trichothecenes on the growth and morphology of Arabidopsis thaliana . J. Exp. Bot. 58 : 1617–1626.

    Nishiuchi T. , 'Phytotoxic effects of trichothecenes on the growth and morphology of Arabidopsis thaliana ' (2007 ) 58 J. Exp. Bot. : 1617 -1626.

    • Search Google Scholar

  • Noctor, G., De Paepe, R., Foyer, C.H. 2007. Mitochondrial redox biology and homeostasis in plants. Trends Plant Sci. 12 : 125–134.

    Foyer C.H. , 'Mitochondrial redox biology and homeostasis in plants ' (2007 ) 12 Trends Plant Sci. : 125 -134.

    • Search Google Scholar

  • Ordog, S.H., Higgins, V.J., Vanlerberghe, G.C. 2002. Mitochondrial Alternative Oxidase Is Not a Critical Component of Plant Viral Resistance But May Play a Role in the Hypersensitive Response. Plant Physiol. 129 : 1858–1865.

    Vanlerberghe G.C. , 'Mitochondrial Alternative Oxidase Is Not a Critical Component of Plant Viral Resistance But May Play a Role in the Hypersensitive Response ' (2002 ) 129 Plant Physiol. : 1858 -1865.

    • Search Google Scholar

  • Overmyer, K. 2002. Hormonal regulation of radical-induced programmed cell death in ozone-sensitive mutants of Arabidopsis thaliana . Academic dissertation, Institute of Biotechnology and Department of Biosciences, Division of Genetics, University of Helsinki, Finland, ISBN 952-10-0326-X.

    Overmyer K. , '', in Hormonal regulation of radical-induced programmed cell death in ozone-sensitive mutants of Arabidopsis thaliana , (2002 ) -.

  • Pan, L., Kawai, M., Yu, L.H., Kim, K.M., Hirata, A., Umeda, M., Uchimiya, H. 2001. The Arabidopsis thaliana ethylene-responsive element binding protein ( At EBP) can function as a dominant suppressor of Bax-induced cell death of yeast. FEBS Lett. 508 : 375–378.

    Uchimiya H. , 'The Arabidopsis thaliana ethylene-responsive element binding protein (AtEBP) can function as a dominant suppressor of Bax-induced cell death of yeast ' (2001 ) 508 FEBS Lett. : 375 -378.

    • Search Google Scholar

  • Poppenberger, B., Berthiller, F., Lucyshyn, D., Sieberer, T., Schuhmacher, R., Krska, R., Kuchler, K., Glossl, J., Luschnig, C., Adam, G, 2003. Detoxification of the Fusarium mycotoxin deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana . J. Biol. Chem. 278 : 47905–47914.

    Adam G. , 'Detoxification of the Fusarium mycotoxin deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana ' (2003 ) 278 J. Biol. Chem. : 47905 -47914.

    • Search Google Scholar

  • Poppenberger, B., Adam, G,, Berthiller, F., Krska, R., Kuchler, K., Luschnig, C., Glossl, J., Lucyshyn, D., Schuhmacher, R., Sieberer, T. 2006. Method for the detoxification of mycotoxins. United States Patent Application Publication No. US2006/0183202 A1.

  • Robson, C.A., Vanlerberghe, G.C. 2002. Transgenic Plant Cells Lacking Mitochondrial Alternative Oxidase Have Increased Susceptibility to Mitochondria-Dependent and-Independent Pathways of Programmed Cell Death. Plant Physiol. 129 : 1908–1920.

    Vanlerberghe G.C. , 'Transgenic Plant Cells Lacking Mitochondrial Alternative Oxidase Have Increased Susceptibility to Mitochondria-Dependent and-Independent Pathways of Programmed Cell Death ' (2002 ) 129 Plant Physiol. : 1908 -1920.

    • Search Google Scholar

  • Sugie, A., Naydenov, N., Mizuno, N., Nakamura, C., Takumi, S. 2006. Overexpression of wheat alternative oxidase gene Waox1a alters respiration capacity and response to reactive oxygen species under low temperature in transgenic Arabidopsis. Genes Genet Syst 81 : 349–354.

    Takumi S. , 'Overexpression of wheat alternative oxidase gene Waox1a alters respiration capacity and response to reactive oxygen species under low temperature in transgenic Arabidopsis ' (2006 ) 81 Genes Genet Syst : 349 -354.

    • Search Google Scholar

  • Sugimoto, M., Sakamoto, W. 1997. Putative phospholipid hydroperoxide glutathione peroxidase gene from Arabidopsis thaliana induced by oxidative stress. Genes Genet. Syst. 72 : 311–316.

    Sakamoto W. , 'Putative phospholipid hydroperoxide glutathione peroxidase gene from Arabidopsis thaliana induced by oxidative stress ' (1997 ) 72 Genes Genet. Syst. : 311 -316.

    • Search Google Scholar

  • Takabatake, R., Hata, S., Taniguchi, M., Kouchi, H., Sugiyama, T., Izui, K. 1999. Isolation and characterization of cDNAs encoding mitochondrial phosphate transporters in soybean, maize, rice, and Arabidopsis. Plant Mol. Biol. 40 : 479–486.

    Izui K. , 'Isolation and characterization of cDNAs encoding mitochondrial phosphate transporters in soybean, maize, rice, and Arabidopsis ' (1999 ) 40 Plant Mol. Biol. : 479 -486.

    • Search Google Scholar

  • Torres, M.A., Jones, J.D.G., Dangl, J.L. 2006. Reactive oxygen species signaling in response to plant pathogens. Plant Physiol. 141 : 373–378.

    Dangl J.L. , 'Reactive oxygen species signaling in response to plant pathogens ' (2006 ) 141 Plant Physiol. : 373 -378.

    • Search Google Scholar

  • Walter, S. Brennan, J.M., Arunachalam, C., Ansari, K.I., Hu, X., Khan, M.R., Trognitz, F., Trognitz, B., Leonard, G., Egan, D., Doohan, F.M. 2008. — Components of the gene network associated with genotype-dependent response of wheat to the Fusarium mycotoxin deoxynivalenol. Func. Integ. Gen. in press (DOI-10.1007/s10142-008-0089-4).
Cover Cereal Research Communications
Cereal Research Communications A Quarterly of the Cereal Research Non-Profit Ltd. Company
Print ISSN:
0133-3720
Online ISSN:
1788-9170
Keywords:
alternative oxidase; adenosine triphosphatase; CEO; cytochrome P450; Fhb1 ; glutathione peroxidase; glutathione transferase; glycosyltransferase; mitochondrial phosphate transporter; multidrug resistance protein; programmed cell death; reactive oxygen species

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